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1,515 Possible Causes for Muscle Spasticity, Peripheral Neuropathy

  • Gaucher Disease

    […] manifestations of GD, such as scoliosis caused by muscle spasticity and respiratory function.[] Comorbidities for peripheral neuropathy were excluded.[] Affected infants may lose previously acquired motor skills and exhibit low muscle tone (hypotonia), involuntary muscle spasms (spasticity) that result in slow, stiff movements[]

  • AMACR Deficiency

    Other features of AMACR deficiency may include weakness and loss of sensation in the limbs due to nerve damage (sensorimotor neuropathy), muscle stiffness (spasticity), and[] Peripheral neuropathy was diagnosed age 57.[] […] stiffness (spasticity), and difficulty coordinating movements (ataxia).[]

  • Adult Krabbe Disease

    neuropathy, abnormal MRI 0.0 0.015 11 p.[] Psychomotor regression, abnormal MRI, abnormal NCVs – 0.0 217 p.I250T (c.749T C)/p.I250T (c.749T C) 15 M 7 years 37 years Spastic paraparesis, optic atrophy, demyelinating peripheral[]

  • Spastic Paraplegia

    It is accompanied by irritability and spastic contractions of the leg muscles. spastic paraplegia Paralysis of both lower limbs with muscle spasm.[] The aim of this study was to identify the genetic cause of the disease in an Italian family with spastic paraplegia and peripheral neuropathy.[] We herein report the first case of Klinefelter syndrome with a rare mosaic form of 47, XXY and 48, XXXY, combined with both spastic paraplegia and peripheral motor neuropathy[]

  • Hereditary Spastic Paraplegia

    Firstly, chronic spasticity might be a risk factor for histopathological muscle alterations.[] This study adds to the evidence associating the known occurrence of mild peripheral neuropathy in the adult onset SPG10 type of AD-HSP.[] Most patients with an SPG3A mutation present with a pure phenotype and early-onset disease, although complicated forms with peripheral neuropathy are also reported.[]

  • Vitamin B12 Deficiency

    […] of muscles, incontinence, paralysis, vision changes, damage to optic nerve (optic neuritis).[] Participation included measuring vitamin B12 levels and assessing peripheral neuropathy using Neuropathy Total Symptom Score-6 (NTSS-6) questionnaire.[] Ataxia (shaky movements and unsteady gait), muscle weakness, spasticity, incontinence, hypotension, vision problems, dementia, psychoses, and mood disturbances are but a few[]

  • Paraplegia

    Firstly, chronic spasticity might be a risk factor for histopathological muscle alterations.[] For example, someone with uncomplicated HSP may have peripheral neuropathy caused by diabetes.[] neuropathy in hereditary spastic paraplegia caused by REEP1 variants. ( 30637453 ) Toft A...Svenstrup K 2019 22 Management of Hereditary Spastic Paraplegia: A Systematic[]

  • Median Neuropathy

    Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology ... cerebellar dysfunction, including dystonia, muscle[] […] concomitant peripheral neuropathy.[] INTRODUCTION: Focal peripheral neuropathy of the median nerve is mainly caused by a traumatic event or pressure, but it may also be produced by systemic illnesses.[]

  • Neuropathy

    Deep tendon reflexes are usually brisk, and muscle tone is spastic.[] […] management of generic peripheral neuropathy.[] Nerve damage caused by injury can also be classified as peripheral neuropathy.[]

  • Parkinson's Disease Type 3

    The drugs L- dopa and baclofen may relieve muscle rigidity and spasticity.[] However, classically, atypical features, including pyramidal and cerebellar signs, peripheral neuropathy, and/or anterior horn cell dysfunction, are also seen.[] , or peripheral neuropathy.[]

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