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31 Possible Causes for Muscle Twitch, Nystagmus, Onset of Dysarthria in Third Decade of Life

  • Spinocerebellar Ataxia Type 1

    (atrophy); and muscle twitches (fasciculations).[ghr.nlm.nih.gov] […] in third to fifth decade of life Pure cerebellar ataxia, nystagmus, dysarthria, dysphagia, hypotonia, and generalized and/or complex partial epilepsy Spinocerebellar ataxia[emedicine.com] All patients underwent a video‐oculographic recording of fixation abnormalities, gaze‐evoked nystagmus, positional and head‐shaking nystagmus, and dysmetric saccades.[doi.org]

  • Hallervorden-Spatz Syndrome

    They may experience involuntary muscle contractions (dystonia) of the head and neck, resulting in repetitive movements and contortions.[ghr.nlm.nih.gov] Clinical features Dystonia Dysarthria Spasticity Choreoathetosis Parkinsonism Hyperreflexia Extensor toe signs Onset in first to third decade of life Gait change / loss of[ncbi.nlm.nih.gov] Nystagmus is often present. These signs usually follow systemic signs such as difficulties in locomotion.[disorders.eyes.arizona.edu]

  • Spinocerebellar Ataxia Type 13

    […] jerks or twitches (myoclonic jerks). [1] [2] [3] [4] Other symptoms may include speech difficulty ( dysarthria ), difficulty eating ( dysphagia ), slowness of movements ([rarediseases.info.nih.gov] […] in third to fifth decade of life Pure cerebellar ataxia, nystagmus, dysarthria, dysphagia, hypotonia, and generalized and/or complex partial epilepsy Spinocerebellar ataxia[emedicine.com] Spinocerebellar ataxia type 13 (SCA13) is a rare autosomal dominant disorder, which, like other types of SCA, is characterized by dysarthria, nystagmus, and ataxia of gait[en.wikipedia.org]

  • Episodic Ataxia

    This abnormality can cause muscle cramping, stiffness, and continuous, fine muscle twitching that appears as rippling under the skin.[ghr.nlm.nih.gov] […] in third to fifth decade of life Pure cerebellar ataxia, nystagmus, dysarthria, dysphagia, hypotonia, and generalized and/or complex partial epilepsy Spinocerebellar ataxia[emedicine.com] Between attacks they have nystagmus and dysarthria. These patients are responsive to acetazolamide.[en.wikipedia.org]

  • Autosomal Dominant Sensory Ataxia

    The episodes are triggered by stress, being startled, or sudden movement and are often associated with muscle twitching.[disabled-world.com] […] in third to fifth decade of life Pure cerebellar ataxia, nystagmus, dysarthria, dysphagia, hypotonia, and generalized and/or complex partial epilepsy Spinocerebellar ataxia[emedicine.medscape.com] […] more bizzare forms of nystagmus can also be seen eg. periodic alternating nystagmus, pendular nystagmus, divergent nystagmus, pure torsional nystagmus on vertical gaze (*[lifeinthefastlane.com]

  • Spinocerebellar Ataxia Type 5

    Those with SCA will also often experience numbness, tingling or pain in their limbs, uncontrolled muscle tensing, muscle wasting and muscle twitching.[indycann.org] The onset of symptoms is usually in the third or fourth decade of life; however, more subtle clinical manifestations can start in early childhood.[ncbi.nlm.nih.gov] The phenotype is characterized by a purely cerebellar syndrome with a downbeat nystagmus occurring prior to the development of other features.[ncbi.nlm.nih.gov]

  • Ataxia

    The episodes are triggered by stress, being startled or sudden movement, and often are associated with muscle twitching.[mayoclinic.org] […] in third to fifth decade of life Pure cerebellar ataxia, nystagmus, dysarthria, dysphagia, hypotonia, and generalized and/or complex partial epilepsy Spinocerebellar ataxia[emedicine.medscape.com] Jittery eye movements - nystagmus . Sensory (Proprioceptive) Ataxia This results from dysfunction to position sensing (proprioceptive) nerve inputs.[mult-sclerosis.org]

  • Autosomal Recessive Spinocerebellar Ataxia 8

    […] of muscles or parts of muscles, without any rhythm or pattern, occurring in various brain disorders) 19q SCA16 39 yrs (20-66) 1-40 years Head and hand tremor 8q SCA17 ( TBP[psychology.wikia.com] […] in third to fifth decade of life Pure cerebellar ataxia, nystagmus, dysarthria, dysphagia, hypotonia, and generalized and/or complex partial epilepsy Spinocerebellar ataxia[emedicine.medscape.com] Findings on examination include spastic and ataxic dysarthria, gaze-evoked nystagmus, limb and gait ataxia, limb spasticity, and diminished vibratory sensation.[ataxia.uchicago.edu]

  • Spastic Ataxia with Congenital Miosis

    Muscle findings of only fasiculations and the workup of such* Definition Muscle twitching is caused by minor muscle contractions in the area, or uncontrollable twitching of[flashcardmachine.com] […] in third to fifth decade of life Pure cerebellar ataxia, nystagmus, dysarthria, dysphagia, hypotonia, and generalized and/or complex partial epilepsy Spinocerebellar ataxia[emedicine.medscape.com] Frequency HPO Source Accession 1 dysarthria 60 33 hallmark (90%) Very frequent (99-80%) HP:0001260 2 congenital miosis 60 33 hallmark (90%) Very frequent (99-80%) HP:0007728 3 nystagmus[malacards.org]

  • Cerebellar Ataxia with Peripheral Neuropathy Type 2

    The episodes are triggered by stress, being startled or sudden movement, and often are associated with muscle twitching.[mayoclinic.org] […] in third to fifth decade of life Pure cerebellar ataxia, nystagmus, dysarthria, dysphagia, hypotonia, and generalized and/or complex partial epilepsy Spinocerebellar ataxia[emedicine.medscape.com] Also observed were moderate incidences of horizontal eye dysmetria, rebound nystagmus, vertical positional nystagmus and visual suppression.[tinnitusjournal.com]

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