Muscle Weakness: Causes & Reasons

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Possible Causes for Muscle Weakness

Vitamin D Deficiency

Apart from the well-known effects on bone metabolism, this condition is also associated with muscle weakness, predominantly of the proximal muscle groups. [ncbi.nlm.nih.gov]

All had generalized bone pain and tenderness, muscle weakness, stooping posture, difficulty walking, and waddling gait due to severe proximal muscle weakness for a period [ncbi.nlm.nih.gov]

We report a four-year-old African boy referred for proximal muscle weakness, fatigability and episodic limb pain. [ncbi.nlm.nih.gov]

Hyperkalemia

Muscle weakness Other names Myasthenia Specialty Neurology Muscle weakness is a lack of muscle strength. [en.wikipedia.org]

Careful monitoring of electrocardiogram changes and muscle weakness in hyperkalemia is important to determine its functional consequences. [acls.com]

However, if symptoms do exist, they typically are muscle weakness, irregular heartbeat, or a slow, weak, or absent pulse. [my.clevelandclinic.org]

Hyperthyroidism

Muscle weakness was more severe in the proximal site than in the distal site. [ncbi.nlm.nih.gov]

She presented with muscle weakness, nausea, vomiting, and diarrhea since one week. The initial diagnosis was TPP. [ncbi.nlm.nih.gov]

These include: Increased heart rate Hand tremor Brisk response to tapping with a reflex hammer Excessive sweating Muscle weakness Protruding eyes If your doctor suspects hyperthyroidism [drugs.com]

Cushing Syndrome

The clinical sign indicative for CS leading to referral to the endocrinologist was muscle weakness in the man and plethora in the woman. [ncbi.nlm.nih.gov]

Symptoms include a round face, thin arms and legs, severe fatigue and muscle weakness, high blood pressure and high blood sugar, purple or pink stretch marks on the skin, [icd10data.com]

Cushing syndrome is characterized by truncal obesity, growth deceleration, skin changes, muscle weakness, and hypertension. [ncbi.nlm.nih.gov]

Muscular Dystrophy

It causes progressive weakness in muscles of the face, arms, legs, and around the shoulders and chest. [ninds.nih.gov]

Weakness of the back muscles can cause scoliosis, while weakness of the abdominal muscles can be the cause of a sagging belly. [nlm.nih.gov]

[…] disorders characterized by muscle weakness and eventual death of the muscle tissues. [icd9data.com]

Duchenne Muscular Dystrophy

Muscle weakness Other names Myasthenia Specialty Neurology Muscle weakness is a lack of muscle strength. [en.wikipedia.org]

Occasionally, however, females who carry a DMD gene mutation may have muscle weakness and cramping. [ghr.nlm.nih.gov]

Proximal muscle weakness affects muscles closest to the body's midline, while distal muscle weakness affects muscles further out on the limbs. [en.wikipedia.org]

Graves Disease

On neurological examination the patient was presented with muscle weakness, muscle atrophy (in face and sternocleidomastoid muscles), features of myotonia and apocamnosis [ncbi.nlm.nih.gov]

weakness and myopathy • Increased DTR • Increased motor activity • Fatigue Cardiovascular • Tachycardia • Palpitations • Repiratory muscle weakness • Increased RR and HR [physio-pedia.com]

Symptoms of hyperthyroidis m include rapid heartbeat, muscle weakness, disturbed sleep, and irritability. [quidel.com]

Rhabdomyolysis

A 71-year-old man was hospitalized because of muscle weakness of the lower limbs that persisted for 1 month. [ncbi.nlm.nih.gov]

Examination revealed proximal symmetrical muscle weakness and arthralgia. The immunological study, electromyography and muscle biopsy confirmed polymyositis. [ncbi.nlm.nih.gov]

Abstract A 91-year-old male was admitted to the hospital for worsening muscle weakness, muscle pain, and unexplained soreness for the past 10 days. [ncbi.nlm.nih.gov]

Motor Neuron Disease

[…] wasting and weakness, absent reflexes, loss of weight and muscle twitching. [mndnsw.asn.au]

Onset was in the second to fourth decade with finger extension weakness, progressing to other distal and sometimes more proximal muscles. [ncbi.nlm.nih.gov]

He developed gait disturbance and weakness of lower limbs at age 52 years. Because of progressive muscle weakness and atrophy, he became bed-ridden at age 65. [ncbi.nlm.nih.gov]

Multifocal Motor Neuropathy

Her disease was difficult to manage with various immunosuppressants, and the muscle weakness eventually progressed to involve the respiratory muscles, necessitating mechanical [ncbi.nlm.nih.gov]

The main symptom is progressive muscle weakness of the arms and legs. [rarediseases.org]

Muscle imbalance and weakness can become so severe that the involved extremity can be rendered nonfunctional. [ncbi.nlm.nih.gov]

Hypokalemia

Eleven patients had a history of recurring muscle weakness. All patients had quadraparesis (muscle weakness in all four limbs); in 10 patients the weakness was severe. [acutecaretesting.org]

Proximal muscle weakness is observed most commonly in lower extremities; cranial muscles are normal, but constipation and distention are prominent. [dovepress.com]

Careful monitoring of electrocardiogram changes and muscle weakness in hyperkalemia is important to determine its functional consequences. [acls.com]

Addison Disease

The physical examination was completely normal except for muscle weakness, hyperpigmentation on labial mucosa and skin in a patient. [ncbi.nlm.nih.gov]

A medical condition in which the adrenal glands do not produce enough cortisol or, in some cases, aldosterone, causing such problems as weight loss, muscle weakness, fatigue [diabetesselfmanagement.com]

Symptoms & Causes The most common symptoms are fatigue, muscle weakness, loss of appetite, weight loss, and abdominal pain. [niddk.nih.gov]

Porphyria

Besides having abdominal and nerve pain, the patient may suffer rapid heartbeat, mania, muscle cramps, muscle weakness, breathing problems, hallucinations, and coma. [rxlist.com]

Acute porphyria can also affect the nervous system causing numbness and muscle weakness. [recordatirarediseases.com]

Other symptoms include: Muscle pain Muscle weakness or paralysis Numbness or tingling Pain in the arms or legs Pain in the back Personality changes Attacks can sometimes be [nlm.nih.gov]

Acute Hepatic Porphyria

It’s also important to address the other symptoms of AIP, like a racing heart (tachycardia) and muscle weakness, because they can lead to complications. [verywellhealth.com]

Muscle weakness. Nausea and vomiting. Constipation. Hypertensive crises. Increased heart rate. Do you have any of these symptoms? [cun.es]

Consider AIP if typical clinical features are seen in the absence of other causes (e.g., unexplained severe abdominal pain accompanied by muscle weakness and dark urine). [amboss.com]

Guillain-Barré Syndrome

But weakness that increases over several days is also common. Muscle weakness or loss of muscle function (paralysis) affects both sides of the body. [nlm.nih.gov]

This leads to nerve inflammation that causes muscle weakness or paralysis and other symptoms. The exact cause of GBS is unknown. [medlineplus.gov]

A medical exam may show muscle weakness. There may also be problems with blood pressure and heart rate. [nlm.nih.gov]

Acute Exertional Rhabdomyolysis

A 62-year-old man was brought to the hospital with back pain and muscle weakness accompanied by myalgia. [blog.goo.ne.jp]

Two patients who demonstrated increased muscle mass, muscle stiffness with variable degrees of muscle weakness and low levels of serum thyroxine (Hoffmann's syndrome) are [scinapse.io]

[…] of SK muscle weakness begins in face muscles (bilat or unil) diplopia, ptosis, difficult chewing, dysphagia, nasal timbre in voice limb and torso weakness may develop resp [quizlet.com]

Secondary Myopathy

Muscle weakness is a common complaint among patients presenting to family physicians. [aafp.org]

In infants, myopathy is evident from muscle weakness and hypotonia. 2 Adults may present with predominant proximal muscle weakness with difficulty in getting up from squatting [chanrejournals.com]

Muscle weakness is usually most severe in muscles of the face, neck and proximal muscles. [rarediseases.org]

Hyponatremia

A 52-year-old Sri Lankan man presented with anorexia, nausea, fatigue, generalized muscle weakness, and cramps for 1 week. [ncbi.nlm.nih.gov]

Other symptoms include: Fatigue Convulsions Headache Muscle weakness or spasms Nausea and vomiting Restlessness Confusion Decreased consciousness Treatment of Hyponatremia [sportsinjuryclinic.net]

weakness, coma, and even seizures! [youtube.com]

Hypercalcemia

She had nausea, vomiting, leg pain, polyuria, polydipsia, and muscle weakness. At the time of relapse, the ionized calcium level was 1.99 mmol/L. [ncbi.nlm.nih.gov]

weakness, depression, anorexia, nausea, and constipation High level of calcium in the blood Higher than normal levels of calcium in the blood. [icd9data.com]

weakness, and weight loss. [ncbi.nlm.nih.gov]

MELAS Syndrome

Most people with MELAS have a build up of lactic acid in the blood above the normal upper limit, which can lead to vomiting, muscle weakness, abdominal pain, fatigue, and [khondrion.com]

Early symptoms may include muscle weakness and pain, recurrent headaches, loss of appetite, vomiting, and seizures. [medlineplus.gov]

This can result in temporary muscle weakness on one side of the body (hemiparesis), altered consciousness, vision and hearing loss, loss of motor skills and intellectual disability [khondrion.com]

Polymyositis

Some cases of polymyositis have manifestations of muscle weakness in the orbital muscles. Rare cases also have weaknesses in facial and bulbar muscles. [symptoma.com]

Abstract Polymyositis is an idiopathic inflammatory myopathy of unknown aetiology that affect skeletal muscles causing symmetrical, proximal muscle weakness, and also other [ncbi.nlm.nih.gov]

Polymyositis-like syndrome in hypothyroidism is a rare condition characterised by proximal muscle weakness and elevated muscle enzymes. [ncbi.nlm.nih.gov]

Limb-Girdle Muscular Dystrophy

However, most patients in the current family showed distal as well as proximal limb weakness rather than weakness of toe and finger flexor muscles that were typical features [ncbi.nlm.nih.gov]

In addition to proximal muscle weakness, there may or may not be: Distal muscle weakness. Muscle hypertrophy. Contractures. [patient.info]

Progressive proximal muscle weakness began again at age 8 years. Serum CK was 14,910 IU/L. She was wheelchair-bound by age 12. [ncbi.nlm.nih.gov]

Facioscapulohumeral Muscular Dystrophy

BACKGROUND: Although muscle weakness is a hallmark of facioscapulohumeral muscular dystrophy (FSHD), the molecular mechanisms that lead to weakness in FSHD remain largely [ncbi.nlm.nih.gov]

Weakness of the back muscles can cause scoliosis, while weakness of the abdominal muscles can be the cause of a sagging belly. [nlm.nih.gov]

Patients present with muscle weakness in these anatomic areas. The muscle weakness eventually spreads to other skeletal muscles as well. [wikidata.org]

Erb Muscular Dystrophy

Muscle weakness may spread from the proximal muscles to affect distal muscles. [rarediseases.org]

It causes progressive weakness in muscles of the face, arms, legs, and around the shoulders and chest. [ninds.nih.gov]

muscle biopsy (examination of a sample of the weak muscle tissue under a microscope), and genetic testing. [msdmanuals.com]

Chronic Inflammatory Demyelinating Polyneuropathy

[…] of the muscle weakness. [ncbi.nlm.nih.gov]

The article presents a boy with progressive generalized muscle weakness and areflexia since the age of two, developed after viral infection. [ncbi.nlm.nih.gov]

Although the patient noticed little muscle weakness, an electrophysiological study demonstrated slow conduction velocities and prolonged distal latencies, with definite conduction [ncbi.nlm.nih.gov]

Leigh's Disease

NARP is characterized by proximal neurogenic muscle weakness with sensory neuropathy, ataxia, and pigmentary retinopathy. [ncbi.nlm.nih.gov]

weakness hypotonia (loss of muscle tone) muscle spasms twitching stiffness in the muscles and joints delayed neurological progress respiratory problems, most notably apnoea [medic8.com]

Affected children may experience delayed development, muscle weakness, problems with movement, or difficulty breathing. [ghr.nlm.nih.gov]

Congenital Muscular Dystrophy

KEYWORDS: Collagen; Fibrosis; IGF-1; Mesenchymal; Mouse; Muscular dystrophy; Skeletal muscles; Weakness [ncbi.nlm.nih.gov]

Congenital muscular dystrophy related to lamin A/C is rare and characterized by early-onset hypotonia with axial muscle weakness typically presenting with a loss in motor [ncbi.nlm.nih.gov]

Congenital muscular dystrophy (CMD) comprises a heterogeneous group of disorders with muscle weakness, hypotonia and contractures present at birth. [ncbi.nlm.nih.gov]

Dermatomyositis

Symptoms may include: Muscle weakness, stiffness, or soreness Problems swallowing Purple color to the upper eyelids Purple-red skin rash Shortness of breath The muscle weakness [nlm.nih.gov]

Later she developed progressive, symmetrical proximal muscle weakness. [ncbi.nlm.nih.gov]

Patient had no muscle weakness and his rash was characteristic of classic dermatomyositis. Skin biopsy was suggestive of dermatomyositis but muscle enzymes were normal. [ncbi.nlm.nih.gov]

Hypokalemic Nephropathy

Careful monitoring of electrocardiogram changes and muscle weakness in hyperkalemia is important to determine its functional consequences. [acls.com]

Due to muscle weakness and cramping, exercise is not effective during the state of hypokalemia. [physio-pedia.com]

There is generalized muscle weakness, characterized by ventroflexion of the neck; other signs include weight loss, chronic vomiting and constipation. [medical-dictionary.thefreedictionary.com]

Brachial Plexus Neuritis

Brachial plexus neuritis is thought to be an immune mediated inflammatory reaction resulting in acute onset of shoulder pain followed by muscle weakness and wasting. [ncbi.nlm.nih.gov]

Within a few hours or days of the condition’s onset, affected individuals may experience muscle weakness, wasting (atrophy), numbness (hyperesthesia), and paralysis of the [diseasesatoz.com]

Pain and muscle weakness occur simultaneously. [aafp.org]