Muscle Weakness: Causes & Reasons

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Possible Causes for Muscle Weakness

Vitamin D Deficiency

Apart from the well-known effects on bone metabolism, this condition is also associated with muscle weakness, predominantly of the proximal muscle groups. [ncbi.nlm.nih.gov]

All had generalized bone pain and tenderness, muscle weakness, stooping posture, difficulty walking, and waddling gait due to severe proximal muscle weakness for a period [ncbi.nlm.nih.gov]

We report a four-year-old African boy referred for proximal muscle weakness, fatigability and episodic limb pain. [ncbi.nlm.nih.gov]

Hyperkalemia

Muscle weakness Other names Myasthenia Specialty Neurology Muscle weakness is a lack of muscle strength. [en.wikipedia.org]

Careful monitoring of electrocardiogram changes and muscle weakness in hyperkalemia is important to determine its functional consequences. [acls.com]

However, if symptoms do exist, they typically are muscle weakness, irregular heartbeat, or a slow, weak, or absent pulse. [my.clevelandclinic.org]

Hyponatremia

A 52-year-old Sri Lankan man presented with anorexia, nausea, fatigue, generalized muscle weakness, and cramps for 1 week. [ncbi.nlm.nih.gov]

weakness, coma, and even seizures! [youtube.com]

Other symptoms include: Fatigue Convulsions Headache Muscle weakness or spasms Nausea and vomiting Restlessness Confusion Decreased consciousness Treatment of Hyponatremia [sportsinjuryclinic.net]

Hypothyroidism

Here we describe a 3-year-old Caucasian girl who was admitted to our Clinic due to pericardial effusion, muscle weakness and weight gain. [ncbi.nlm.nih.gov]

People with hypothyroidism-induced myopathy often complain of muscle pain and stiffness, along with proximal muscle weakness that can make simple activities like rising from [verywellhealth.com]

These include: sluggishness depression dry skin or hair loss feeling cold muscle weakness poor memory or trouble concentrating constipation facial puffiness weight gain (even [kidshealth.org]

Muscle Strain

The case was considered to have moderate muscle strain, because he had modest muscle weakness with a negative lift-off test. [ncbi.nlm.nih.gov]

[…] or unable to move at all Muscle weakness Muscle spasms (result of scar tissue forming) Uneven or deformed surface of the skin A muscle strain can seem like a minor nuisance [bermanchiropractic.com]

Quadriceps tears are generally caused from sudden overload, muscle fatigue, muscle weakness, an imbalance between quadriceps and hamstring strength, a poor training program [psmgroup.com.au]

Neuropathy

It is manifested with pain, tingling, numbness, and muscle weakness. [fpnotebook.com]

This syndrome is associated with myokymia, muscle cramps and stiffness, delayed muscle relaxation after contraction, muscle weakness, and hyperhydrosis. [go.gale.com]

weakness especially in the feet. [imedpub.com]

Chronic Kidney Insufficiency

weakness. [emedicine.medscape.com]

Severe muscle weakness. To check your heart rate, see the instructions for taking a pulse. [uwhealth.org]

Reduced albumin synthesis Lack of adaptation to a low-protein diet Hence, metabolic acidosis is associated with protein-energy malnutrition, loss of lean body mass, and muscle [emedicine.medscape.com]

Acute Kidney Injury

Muscle weakness. When your body's fluids and electrolytes — your body's blood chemistry — are out of balance, muscle weakness can result. Permanent kidney damage. [mayoclinic.org]

weakness, paralysis and heart rhythm problems fluid in the lungs (pulmonary oedema ) acidic blood (metabolic acidosis) – which can cause nausea, vomiting, drowsiness and [nhs.uk]

Complications of acute kidney injury The most serious complications of acute kidney injury are: high levels of potassium in the blood – in severe cases, this can lead to muscle [nhs.uk]

Peripheral Neuropathy

A 55-year-old woman with consanguineous parents developed slowly progressive, asymmetric muscle weakness and atrophy in her forearms, while her ability to walk remained unaffected [ncbi.nlm.nih.gov]

We present a 70-year-old male patient of Greek origin with choreatic movements of the tongue and face, lower limb muscle weakness, peripheral neuropathy, elevated creatinephosphokinase [ncbi.nlm.nih.gov]

It is manifested with pain, tingling, numbness, and muscle weakness. [fpnotebook.com]

Hyperthyroidism

She presented with muscle weakness, nausea, vomiting, and diarrhea since one week. The initial diagnosis was TPP. [ncbi.nlm.nih.gov]

Muscle weakness was more severe in the proximal site than in the distal site. [ncbi.nlm.nih.gov]

However, in the longer term, less desirable symptoms, such as muscle weakness, insomnia and trembling can also result. [thyroid-info.com]

Polymyalgia Rheumatica

Polymyalgia rheumatica (PMR) is classified as diffuse soft tissue rheumatism with characteristic pain and stiffness of proximal extremities/muscles without muscle weakness [youtube.com]

There is no true muscle weakness nor evidence of muscle disease on electromyography (EMG) or on biopsy. [healthcentral.com]

weakness. [youtube.com]

Chronic Fatigue Syndrome

In all three groups, a majority of patients exhibited muscle weakness in the lower limbs, and significant numbers of patients had absent or abnormal reflexes. [ncbi.nlm.nih.gov]

Other symptoms include sore throat, fever, muscle weakness, headache, and joint pain A syndrome characterized by persistent or recurrent fatigue, diffuse musculoskeletal pain [icd9data.com]

Other common symptoms include: Joint pain without swelling or redness, muscle aches, muscle weakness all over, or headaches that differ from those you have had in the past [nlm.nih.gov]

Cushing Syndrome

The clinical sign indicative for CS leading to referral to the endocrinologist was muscle weakness in the man and plethora in the woman. [ncbi.nlm.nih.gov]

Symptoms include a round face, thin arms and legs, severe fatigue and muscle weakness, high blood pressure and high blood sugar, purple or pink stretch marks on the skin, [icd10data.com]

Cushing syndrome is characterized by truncal obesity, growth deceleration, skin changes, muscle weakness, and hypertension. [ncbi.nlm.nih.gov]

Lumbar Disk Herniation

Common symptoms of lumbar disc protrusion include: Chronic low back pain Pain, numbness and tingling in the legs, feet and toes Back stiffness or soreness Muscle weakness [laserspineinstitute.com]

Although age is the most common risk, physical inactivity can cause weak back and abdominal muscles, which may not support the spine properly. [hopkinsmedicine.org]

[…] and travels down the leg to the calf or into the foot Muscle weakness in the legs Numbness in the leg or foot Decreased reflexes at the knee or ankle Changes in bladder or [hopkinsmedicine.org]

Polyneuropathy

After eliminating possible factors, septic shock-induced respiratory muscle weakness was suspected. [ncbi.nlm.nih.gov]

[…] syndrome: burning pain, tingling, pins-and-needles sensation, or formication. hyperhidrosis Atrophy and paresis of muscles: e.g., “stork legs” in the case of HMSN type I [amboss.com]

Clinically, they manifest as limb and respiratory muscle weakness. [ncbi.nlm.nih.gov]

Muscular Dystrophy

It causes progressive weakness in muscles of the face, arms, legs, and around the shoulders and chest. [ninds.nih.gov]

Weakness of the back muscles can cause scoliosis, while weakness of the abdominal muscles can be the cause of a sagging belly. [nlm.nih.gov]

Occasionally, however, females who carry a DMD gene mutation may have muscle weakness and cramping. [web.archive.org]

Duchenne Muscular Dystrophy

Muscle weakness Other names Myasthenia Specialty Neurology Muscle weakness is a lack of muscle strength. [en.wikipedia.org]

Occasionally, however, females who carry a DMD gene mutation may have muscle weakness and cramping. [ghr.nlm.nih.gov]

Proximal muscle weakness affects muscles closest to the body's midline, while distal muscle weakness affects muscles further out on the limbs. [en.wikipedia.org]

Graves Disease

On neurological examination the patient was presented with muscle weakness, muscle atrophy (in face and sternocleidomastoid muscles), features of myotonia and apocamnosis [ncbi.nlm.nih.gov]

Flajani–Basedow–Graves disease The classic finding of exophthalmos and lid retraction in Graves' disease Specialty Endocrinology Symptoms Enlarged thyroid, irritability, muscle [en.wikipedia.org]

This case emphasises the importance of considering TPP in patients with acute muscle weakness and the importance of promptly initiating treatment and preventing relapse of [ncbi.nlm.nih.gov]

Addison Disease

The physical examination was completely normal except for muscle weakness, hyperpigmentation on labial mucosa and skin in a patient. [ncbi.nlm.nih.gov]

Symptoms & Causes The most common symptoms are fatigue, muscle weakness, loss of appetite, weight loss, and abdominal pain. [niddk.nih.gov]

A medical condition in which the adrenal glands do not produce enough cortisol or, in some cases, aldosterone, causing such problems as weight loss, muscle weakness, fatigue [diabetesselfmanagement.com]

Rheumatoid Arthritis

Fatigue, muscle weakness, and weight loss are common symptoms. [britannica.com]

weakness and thinning of the skin. [nhsinform.scot]

It can cause arthralgias and weakness in intrinsic muscles of the hand. [ncbi.nlm.nih.gov]

Rhabdomyolysis

A 71-year-old man was hospitalized because of muscle weakness of the lower limbs that persisted for 1 month. [ncbi.nlm.nih.gov]

Examination revealed proximal symmetrical muscle weakness and arthralgia. The immunological study, electromyography and muscle biopsy confirmed polymyositis. [ncbi.nlm.nih.gov]

Abstract A 91-year-old male was admitted to the hospital for worsening muscle weakness, muscle pain, and unexplained soreness for the past 10 days. [ncbi.nlm.nih.gov]

Electrolyte Imbalance

Hypernatremia Muscle weakness, leg cramps, fatigue, lethargy, anorexia, nosia, vomiting, decreased bowel sounds/motility, arrhythmia, depressed deep-tendon reflexes, weak [memorize.com]

Once again, your muscles are affected. You will have cramps, muscle weakness and even constipation. [livestrong.com]

Hypokalemia GI hyperactivity, diarrhea, irritability, apathy, confusion, muscle weakness/ areflexia, irregular pulse, decreased h.r, paresthesias, extremity numbness. [memorize.com]

Motor Neuron Disease

[…] wasting and weakness, absent reflexes, loss of weight and muscle twitching. [mndnsw.asn.au]

Onset was in the second to fourth decade with finger extension weakness, progressing to other distal and sometimes more proximal muscles. [ncbi.nlm.nih.gov]

He developed gait disturbance and weakness of lower limbs at age 52 years. Because of progressive muscle weakness and atrophy, he became bed-ridden at age 65. [ncbi.nlm.nih.gov]

Entrapment Neuropathy

Typical symptoms include muscle weakness, pain, numbness and tingling. [epainassist.com]

Manual muscle-strength testing revealed weakness in several muscles and deep tendon reflexes were absent in the upper extremities. [touchneurology.com]

This leads to altered sensation in the foot and toes such as numbness, tingling and burning sensation and weakness of the foot muscles. [epainassist.com]

Multifocal Motor Neuropathy

Her disease was difficult to manage with various immunosuppressants, and the muscle weakness eventually progressed to involve the respiratory muscles, necessitating mechanical [ncbi.nlm.nih.gov]

The main symptom is progressive muscle weakness of the arms and legs. [rarediseases.org]

The initial high-dose intravenous immunoglobulin treatment significantly improved left upper limb muscle weakness. [ncbi.nlm.nih.gov]

Porphyria

Besides having abdominal and nerve pain, the patient may suffer rapid heartbeat, mania, muscle cramps, muscle weakness, breathing problems, hallucinations, and coma. [rxlist.com]

It is therefore advisable to hospitalize the patient, particularly if there is muscle weakness. [cghjournal.org]

Other symptoms include: Muscle pain Muscle weakness or paralysis Numbness or tingling Pain in the arms or legs Pain in the back Personality changes Attacks can sometimes be [nlm.nih.gov]

Hypokalemia

Neurological examination showed a lower extremity muscle weakness with three-fifths muscular strength of the quadriceps and tibialis anterior muscle on both sides. [ncbi.nlm.nih.gov]

Eleven patients had a history of recurring muscle weakness. All patients had quadraparesis (muscle weakness in all four limbs); in 10 patients the weakness was severe. [acutecaretesting.org]

Clinical features include transient periods of muscle weakness and tetany, dizziness, abdominal pains and constipation. [ncbi.nlm.nih.gov]

Talipes Cavus

Although it is a relatively common disorder affecting the foot and ankle, little is known about the distribution of muscle weakness, severity of orthopaedic deformities, or [cvbuilder.hft.org.uk]

A hypothetical model proposed by various authors describes a relationship whereby weak evertor muscles are overpowered by stronger invertor muscles causing an adducted forefoot [teitelbaum-cped.com]

An agonist and antagonist model for the muscles determines the deformity. In CMT, the anterior tibialis muscle and the peroneus muscle develop weaknesses. [physio-pedia.com]

Leptomeningeal Metastasis

Cranial nerve symptoms including visual loss, diplopia, hearing loss, dysphagia, ocular muscle weakness, facial weakness and facial pain are also seen. [adventhealthcancerinstitute.com]

Physical examination also revealed mild paresis of the upper arm muscles and the muscles involved in dorsiflexion of the left foot. [bloodjournal.org]

[…] bright light, difficulty moving upper eyelid Trochlear nerve: Double vision Trigeminal nerve: Facial pain Abducens: Double vision (sixth nerve palsy) Facial nerve: Facial muscle [verywellhealth.com]

Guillain-Barré Syndrome

But weakness that increases over several days is also common. Muscle weakness or loss of muscle function (paralysis) affects both sides of the body. [nlm.nih.gov]

This leads to nerve inflammation that causes muscle weakness or paralysis and other symptoms. The exact cause of GBS is unknown. [medlineplus.gov]

A medical exam may show muscle weakness. There may also be problems with blood pressure and heart rate. [nlm.nih.gov]