Muscle Weakness: Causes & Reasons

Warning: Do not use in emergencies, if pregnant, if under 18, or as a substitute for a doctor’s advice or diagnosis. Learn more

Possible Causes for Muscle Weakness

Vitamin D Deficiency

Apart from the well-known effects on bone metabolism, this condition is also associated with muscle weakness, predominantly of the proximal muscle groups. [ncbi.nlm.nih.gov]

All had generalized bone pain and tenderness, muscle weakness, stooping posture, difficulty walking, and waddling gait due to severe proximal muscle weakness for a period [ncbi.nlm.nih.gov]

We report a four-year-old African boy referred for proximal muscle weakness, fatigability and episodic limb pain. [ncbi.nlm.nih.gov]

Hyperkalemia

Careful monitoring of electrocardiogram changes and muscle weakness in hyperkalemia is important to determine its functional consequences. [acls.com]

However, if symptoms do exist, they typically are muscle weakness, irregular heartbeat, or a slow, weak, or absent pulse. [my.clevelandclinic.org]

Signs and symptoms include muscle weakness, paralysis, hypothermia, and cardiac abnormalities (irregular conduction and arrhythmias). [visualdx.com]

Hyperthyroidism

Muscle weakness was more severe in the proximal site than in the distal site. [ncbi.nlm.nih.gov]

She presented with muscle weakness, nausea, vomiting, and diarrhea since one week. The initial diagnosis was TPP. [ncbi.nlm.nih.gov]

These include: Increased heart rate Hand tremor Brisk response to tapping with a reflex hammer Excessive sweating Muscle weakness Protruding eyes If your doctor suspects hyperthyroidism [drugs.com]

Hyponatremia

A 52-year-old Sri Lankan man presented with anorexia, nausea, fatigue, generalized muscle weakness, and cramps for 1 week. [ncbi.nlm.nih.gov]

Other symptoms include: Fatigue Convulsions Headache Muscle weakness or spasms Nausea and vomiting Restlessness Confusion Decreased consciousness Treatment of Hyponatremia [sportsinjuryclinic.net]

weakness, coma, and even seizures! [youtube.com]

Cushing Syndrome

The clinical sign indicative for CS leading to referral to the endocrinologist was muscle weakness in the man and plethora in the woman. [ncbi.nlm.nih.gov]

Symptoms include a round face, thin arms and legs, severe fatigue and muscle weakness, high blood pressure and high blood sugar, purple or pink stretch marks on the skin, [icd10data.com]

Cushing syndrome is characterized by truncal obesity, growth deceleration, skin changes, muscle weakness, and hypertension. [ncbi.nlm.nih.gov]

Muscular Dystrophy

It causes progressive weakness in muscles of the face, arms, legs, and around the shoulders and chest. [ninds.nih.gov]

Weakness of the back muscles can cause scoliosis, while weakness of the abdominal muscles can be the cause of a sagging belly. [nlm.nih.gov]

From Wikidata Jump to navigation Jump to search myopathy characterized by progressive skeletal muscle weakness degeneration edit English muscular dystrophy myopathy characterized [wikidata.org]

Duchenne Muscular Dystrophy

Occasionally, however, females who carry a DMD gene mutation may have muscle weakness and cramping. [ghr.nlm.nih.gov]

Generally, proximal muscle weakness is noticed earlier followed by distal muscle weakness. [symptoma.com]

Muscular dystrophies are a group of genetic conditions characterized by progressive muscle weakness and wasting (atrophy). [ghr.nlm.nih.gov]

Graves Disease

On neurological examination the patient was presented with muscle weakness, muscle atrophy (in face and sternocleidomastoid muscles), features of myotonia and apocamnosis [ncbi.nlm.nih.gov]

weakness and myopathy • Increased DTR • Increased motor activity • Fatigue Cardiovascular • Tachycardia • Palpitations • Repiratory muscle weakness • Increased RR and HR [physio-pedia.com]

Symptoms of hyperthyroidis m include rapid heartbeat, muscle weakness, disturbed sleep, and irritability. [quidel.com]

Polymyalgia Rheumatica

Polymyalgia rheumatica (PMR) is classified as diffuse soft tissue rheumatism with characteristic pain and stiffness of proximal extremities/muscles without muscle weakness [youtube.com]

There is no true muscle weakness nor evidence of muscle disease on electromyography (EMG) or on biopsy. [healthcentral.com]

weakness. [youtube.com]

Addison Disease

The physical examination was completely normal except for muscle weakness, hyperpigmentation on labial mucosa and skin in a patient. [ncbi.nlm.nih.gov]

A medical condition in which the adrenal glands do not produce enough cortisol or, in some cases, aldosterone, causing such problems as weight loss, muscle weakness, fatigue [diabetesselfmanagement.com]

Symptoms & Causes The most common symptoms are fatigue, muscle weakness, loss of appetite, weight loss, and abdominal pain. [niddk.nih.gov]

Rhabdomyolysis

A 71-year-old man was hospitalized because of muscle weakness of the lower limbs that persisted for 1 month. [ncbi.nlm.nih.gov]

Examination revealed proximal symmetrical muscle weakness and arthralgia. The immunological study, electromyography and muscle biopsy confirmed polymyositis. [ncbi.nlm.nih.gov]

Abstract A 91-year-old male was admitted to the hospital for worsening muscle weakness, muscle pain, and unexplained soreness for the past 10 days. [ncbi.nlm.nih.gov]

Motor Neuron Disease

[…] wasting and weakness, absent reflexes, loss of weight and muscle twitching. [mndnsw.asn.au]

Onset was in the second to fourth decade with finger extension weakness, progressing to other distal and sometimes more proximal muscles. [ncbi.nlm.nih.gov]

He developed gait disturbance and weakness of lower limbs at age 52 years. Because of progressive muscle weakness and atrophy, he became bed-ridden at age 65. [ncbi.nlm.nih.gov]

Multifocal Motor Neuropathy

Her disease was difficult to manage with various immunosuppressants, and the muscle weakness eventually progressed to involve the respiratory muscles, necessitating mechanical [ncbi.nlm.nih.gov]

The main symptom is progressive muscle weakness of the arms and legs. [rarediseases.org]

Muscle imbalance and weakness can become so severe that the involved extremity can be rendered nonfunctional. [ncbi.nlm.nih.gov]

Porphyria

Besides having abdominal and nerve pain, the patient may suffer rapid heartbeat, mania, muscle cramps, muscle weakness, breathing problems, hallucinations, and coma. [rxlist.com]

Acute porphyria can also affect the nervous system causing numbness and muscle weakness. [recordatirarediseases.com]

Other symptoms include: Muscle pain Muscle weakness or paralysis Numbness or tingling Pain in the arms or legs Pain in the back Personality changes Attacks can sometimes be [nlm.nih.gov]

Hypokalemia

Eleven patients had a history of recurring muscle weakness. All patients had quadraparesis (muscle weakness in all four limbs); in 10 patients the weakness was severe. [acutecaretesting.org]

Proximal muscle weakness is observed most commonly in lower extremities; cranial muscles are normal, but constipation and distention are prominent. [dovepress.com]

Careful monitoring of electrocardiogram changes and muscle weakness in hyperkalemia is important to determine its functional consequences. [acls.com]

Acute Exertional Rhabdomyolysis

A 62-year-old man was brought to the hospital with back pain and muscle weakness accompanied by myalgia. [blog.goo.ne.jp]

Two patients who demonstrated increased muscle mass, muscle stiffness with variable degrees of muscle weakness and low levels of serum thyroxine (Hoffmann's syndrome) are [scinapse.io]

[…] of SK muscle weakness begins in face muscles (bilat or unil) diplopia, ptosis, difficult chewing, dysphagia, nasal timbre in voice limb and torso weakness may develop resp [quizlet.com]

Acute Hepatic Porphyria

Symptoms that impact the nervous system include: Pain in arms, legs, chest, back, neck, or head Muscle weakness Mental symptoms like agitation, confusion, depression, and/ [iffgd.org]

It’s also important to address the other symptoms of AIP, like a racing heart (tachycardia) and muscle weakness, because they can lead to complications. [verywellhealth.com]

Muscle weakness. Nausea and vomiting. Constipation. Hypertensive crises. Increased heart rate. Do you have any of these symptoms? [cun.es]

Guillain-Barré Syndrome

But weakness that increases over several days is also common. Muscle weakness or loss of muscle function (paralysis) affects both sides of the body. [nlm.nih.gov]

This leads to nerve inflammation that causes muscle weakness or paralysis and other symptoms. The exact cause of GBS is unknown. [medlineplus.gov]

A medical exam may show muscle weakness. There may also be problems with blood pressure and heart rate. [nlm.nih.gov]

Chronic Inflammatory Demyelinating Polyneuropathy

[…] of the muscle weakness. [ncbi.nlm.nih.gov]

The article presents a boy with progressive generalized muscle weakness and areflexia since the age of two, developed after viral infection. [ncbi.nlm.nih.gov]

Although the patient noticed little muscle weakness, an electrophysiological study demonstrated slow conduction velocities and prolonged distal latencies, with definite conduction [ncbi.nlm.nih.gov]

Leigh's Disease

NARP is characterized by proximal neurogenic muscle weakness with sensory neuropathy, ataxia, and pigmentary retinopathy. [ncbi.nlm.nih.gov]

weakness hypotonia (loss of muscle tone) muscle spasms twitching stiffness in the muscles and joints delayed neurological progress respiratory problems, most notably apnoea [medic8.com]

Affected children may experience delayed development, muscle weakness, problems with movement, or difficulty breathing. [ghr.nlm.nih.gov]

Hypercalcemia

She had nausea, vomiting, leg pain, polyuria, polydipsia, and muscle weakness. At the time of relapse, the ionized calcium level was 1.99 mmol/L. [ncbi.nlm.nih.gov]

weakness, depression, anorexia, nausea, and constipation High level of calcium in the blood Higher than normal levels of calcium in the blood. [icd9data.com]

weakness, and weight loss. [ncbi.nlm.nih.gov]

Secondary Myopathy

In infants, myopathy is evident from muscle weakness and hypotonia. 2 Adults may present with predominant proximal muscle weakness with difficulty in getting up from squatting [chanrejournals.com]

Muscle weakness is usually most severe in muscles of the face, neck and proximal muscles. [rarediseases.org]

weakness Critical illness neuropathy Failure to wean off ventilation Amyloid myopathy Rare Proximal > distal muscle weakness Pseudohypertrophy of muscles Palpable muscle [clevelandclinicmeded.com]

MELAS Syndrome

Early symptoms may include muscle weakness and pain, recurrent headaches, loss of appetite, vomiting, and seizures. [sites.google.com]

Increased acidity in the blood can lead to vomiting, abdominal pain, extreme tiredness (fatigue), muscle weakness, and difficulty breathing. [ghr.nlm.nih.gov]

In most cases, the signs and symptoms of this disorder appear in childhood following a period of normal development. [3] Early symptoms may include muscle weakness and pain [en.wikipedia.org]

Acute Intermittent Porphyria

weakness. [ncbi.nlm.nih.gov]

Following metoclopramide and diclofenac treatment, she became hyponatremic (serum Na 120 meq/l) and quadriparetic with respiratory muscle weakness. [endocrine-abstracts.org]

weakness, or mental symptoms, in the absence of other obvious causes. [ncbi.nlm.nih.gov]

Polymyositis

Some cases of polymyositis have manifestations of muscle weakness in the orbital muscles. Rare cases also have weaknesses in facial and bulbar muscles. [symptoma.com]

Abstract Polymyositis is an idiopathic inflammatory myopathy of unknown aetiology that affect skeletal muscles causing symmetrical, proximal muscle weakness, and also other [ncbi.nlm.nih.gov]

Polymyositis-like syndrome in hypothyroidism is a rare condition characterised by proximal muscle weakness and elevated muscle enzymes. [ncbi.nlm.nih.gov]

Limb-Girdle Muscular Dystrophy

In addition to proximal muscle weakness, there may or may not be: Distal muscle weakness. Muscle hypertrophy. Contractures. [patient.info]

Progressive proximal muscle weakness began again at age 8 years. Serum CK was 14,910 IU/L. She was wheelchair-bound by age 12. [ncbi.nlm.nih.gov]

She was brought to medical attention at age 12, not because of muscle weakness, but due to episodes of tachycardia caused by Wolff-Parkinson-White syndrome. [ncbi.nlm.nih.gov]

Facioscapulohumeral Muscular Dystrophy

BACKGROUND: Although muscle weakness is a hallmark of facioscapulohumeral muscular dystrophy (FSHD), the molecular mechanisms that lead to weakness in FSHD remain largely [ncbi.nlm.nih.gov]

Weakness of the back muscles can cause scoliosis, while weakness of the abdominal muscles can be the cause of a sagging belly. [nlm.nih.gov]

Patients present with muscle weakness in these anatomic areas. The muscle weakness eventually spreads to other skeletal muscles as well. [wikidata.org]

Erb Muscular Dystrophy

Muscle weakness may spread from the proximal muscles to affect distal muscles. [rarediseases.org]

It causes progressive weakness in muscles of the face, arms, legs, and around the shoulders and chest. [ninds.nih.gov]

muscle biopsy (examination of a sample of the weak muscle tissue under a microscope), and genetic testing. [msdmanuals.com]

Hypokalemic Nephropathy

Careful monitoring of electrocardiogram changes and muscle weakness in hyperkalemia is important to determine its functional consequences. [acls.com]

Due to muscle weakness and cramping, exercise is not effective during the state of hypokalemia. [physio-pedia.com]

There is generalized muscle weakness, characterized by ventroflexion of the neck; other signs include weight loss, chronic vomiting and constipation. [medical-dictionary.thefreedictionary.com]

Congenital Muscular Dystrophy

Congenital muscular dystrophy related to lamin A/C is rare and characterized by early-onset hypotonia with axial muscle weakness typically presenting with a loss in motor [ncbi.nlm.nih.gov]

Congenital muscular dystrophy (CMD) comprises a heterogeneous group of disorders with muscle weakness, hypotonia and contractures present at birth. [ncbi.nlm.nih.gov]

[…] tone (hypotonia) and muscle weakness at birth. [rarediseases.org]