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310 Possible Causes for Muscle Weakness - Upper and Lower Limbs

  • Primary CD59 Deficiency

    Kumar & Clark s Clinical Medicine 8 builds on the prize-winning formula that won the first prize in the BMA Book Awards Medicine Category in 2010 (7th edition) and 2006 (6th edition). This book is comprehensive, student friendly (if still intimidating in size!) and covers such a vast breadth of knowledge. It still[…][]

  • Autosomal Dominant Limb-Girdle Muscular Dystrophy Type 1H

    LGMD1H is a form of muscular dystrophy characterized by a slow progression of proximal muscle weakness in both upper and lower limbs affecting several members of a four generations[] Five subjects presented with a slowly progressive proximal muscle weakness, in both upper and lower limbs, with onset during the fourth-fifth decade of life, which fulfilled[] […] both the upper and lower limbs (Bisceglia et al., 2010).[]

  • Hyperventilation

    A five-months-pregnant female of the age 25 years presented with sudden onset flaccid weakness of both lower limbs associated with thigh muscle pain followed by weakness of[] […] both upper limbs within three days.[]

  • Stroke

    The second patient is a 42-year-old man who had spasticity and hemiplegia in both upper and lower limbs on the right side 32 months after a left cerebral hemorrhage.[] The first patient is a 57-year-old man who experienced permanent muscle weakness in his left leg after a right cerebral infarction.[]

  • Squamous Cell Carcinoma of the Lung

    Dehydration and lower limb muscle weakness were noted, as were laboratory findings of coagulation abnormalities and renal dysfunction.[] Computed tomography helped confirm a 21-mm peripheral nodule in the upper left lobe of the lung, with associated swollen lymph nodes in the bilateral hilar, mediastinal, and[]

  • Whiplash Injury

    Numbness, weakness, paraesthesia, sphincter disturbance and increase in relexes in upper limbs and lower limbs in cases of cord injury Retropharyngeal [behind the pharynx][] The symptoms may include: Pain in neck and jaw with or without decrease in range of movements Tightness in paraspinal muscles muscle tightness and spasm Interscapular pain[]

  • Diabetic Autonomic Neuropathy

    The main clinical feature of HSN I is a reduction of sensation sense, mainly distributed around the distal parts of the upper and lower limbs.[] Variable distal muscle weakness and wasting, and chronic skin ulcers are characteristic. Autonomic features (usually sweating disturbances) are invariably observed.[]

  • Hyperthyroidism

    Neurological examination showed weakness in the muscles of the bilateral upper and lower limbs.[] Muscle weakness was more severe in the proximal site than in the distal site.[]

  • Spinal Stenosis

    Signs and symptoms of cervical stenosis include a spastic gait, upper extremity numbness, upper extremity and lower extremity weakness, radicular pain in the upper limbs,[] Symptoms and Treatment of Stenosis Symptoms of cervical (neck) stenosis can include reflex abnormalities, weakness of the upper or lower limbs, radicular pain in the arms,[] […] urinary incontinence, fecal incontinence, muscle wasting, sensory deficits, and reflex abnormalities.[]

  • Narrow Cervical Spinal Canal

    Symptoms and Treatment of Stenosis Symptoms of cervical (neck) stenosis can include reflex abnormalities, weakness of the upper or lower limbs, radicular pain in the arms,[] […] sensory deficits, and possible wasting of the muscles.[] Symptoms of lumbar (lower back) stenosis may include loss of deep tendon reflexes (DTR), leg pain, and weakness in the legs.[]

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