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398 Possible Causes for Muscle Weakness - Upper and Lower Limbs

  • Urticarial Vasculitis

    During the course of her hospitalization, she was also found to have profound proximal muscle weakness in both upper and lower limbs associated with raised creatinine kinase[ncbi.nlm.nih.gov] A muscle biopsy was performed, which demonstrated evidence of an inflammatory myositis with vasculitis, which had returned despite on-going immunosuppression.[ncbi.nlm.nih.gov]

  • Autosomal Dominant Limb-Girdle Muscular Dystrophy Type 1A

    Symptoms - Muscular dystrophy- limb-girdle- type 1A Nasal voice Achilles tendon contractures Upper limb girdle muscle weakness Upper limb girdle muscle wasting Lower limb[checkorphan.org] Overview An autosomal dominant form of limb-girdle muscular dystrophy where muscle weakness and atrophy is caused by mutations of the myotilin gene.[checkorphan.org] […] muscle weakness Lower limb muscle wasting Causes - Muscular dystrophy- limb-girdle- type 1A Muscular dystrophy is caused by various genetic mechanisms.[checkorphan.org]

  • Bethlem Myopathy

    She had proximal muscle weakness of both upper and lower limbs and was ambulant till the age of 9 years.[neurologyindia.com]

  • Autosomal Recessive Progressive External Ophthalmoplegia

    Whole-exome sequencing using next-generation technologies has been previously demonstrated to be able to detect rare disease-causing variants. Progressive external ophthalmoplegia (PEO) is an inherited mitochondrial disease that follows either autosomal dominant or recessive forms of inheritance (adPEO or arPEO).[…][ncbi.nlm.nih.gov]

  • Primary CD59 Deficiency

    Abstract Background. CD59 encodes a 77-amino acid glycosylphosphatidylinositol (GPI)-anchored cell surface glycoprotein synthesized as a 128-amino acid protein that includes a signal sequence and the sequence for a GPI anchor replacement. The CD59 protein inhibits the final and most important step of membrane[…][bloodjournal.org]

  • Chorea

    Intensive propulsion, involuntary muscle movements (limbs and face), muscle weakness of left upper and lower limbs, and “walk dance” were observed ( Video ).[wwwnc.cdc.gov] Video Intensive propulsion, involuntary muscle movements (limbs and face), muscle weakness of left upper and lower limbs, and “walk dance” in 38-year-old man with tick-borne[wwwnc.cdc.gov] Physical examination revealed palsy in the seventh facial nerve, tremor in the facial muscles on the left side, muscle weakness in the left upper and lower limbs, and positive[wwwnc.cdc.gov]

  • Muscular Atrophy

    A 62-year-old man presented with progressive muscle weakness, fasciculations in upper and lower limbs and dysesthesia predominantly in the distal regions.[ncbi.nlm.nih.gov]

  • Lyme Disease

    A 64-year-old man presented with a 1-month history of rapidly progressive weakness involving bulbar, upper limb and lower limb muscles.[ncbi.nlm.nih.gov] The physical examination showed widespread weakness, atrophy, fasciculation, and brisk reflexes.[ncbi.nlm.nih.gov]

  • Hyperventilation

    A five-months-pregnant female of the age 25 years presented with sudden onset flaccid weakness of both lower limbs associated with thigh muscle pain followed by weakness of[ncbi.nlm.nih.gov] […] both upper limbs within three days.[ncbi.nlm.nih.gov]

  • Respiratory Alkalosis

    A five-months-pregnant female of the age 25 years presented with sudden onset flaccid weakness of both lower limbs associated with thigh muscle pain followed by weakness of[ncbi.nlm.nih.gov] […] both upper limbs within three days.[ncbi.nlm.nih.gov]

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