Muscular Atrophy: Causes & Reasons

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Possible Causes for Muscular Atrophy

Muscular Dystrophy

Spinal muscular atrophies: Amyotrophic lateral sclerosis (ALS), or motor neuron disease Infantile progressive spinal muscular atrophy Intermediate spinal muscular atrophy [urmc.rochester.edu]

Spinal muscular atrophies Amyotrophic lateral sclerosis (ALS), or motor neuron disease Infantile progressive spinal muscular atrophy Intermediate spinal muscular atrophy Juvenile [hopkinsmedicine.org]

Distal muscular dystrophies are a group of inherited primary muscle disorders showing progressive weakness and atrophy preferentially in the hands, forearm, lower legs, or [ncbi.nlm.nih.gov]

Progressive Muscular Atrophy

The name "spinal muscular atrophy" is ambiguous as it refers to any of various spinal muscular atrophies, including the autosomal recessive spinal muscular atrophy caused [en.wikipedia.org]

[…] in weakness and muscular atrophy, usually without evidence of injury to the corticospinal tracts Applies To Duchenne-Aran muscular atrophy Progressive muscular atrophy (pure [icd9data.com]

KEYWORDS: Lower motor neuron syndrome; Lower motor neuron-onset ALS; PMA; Progressive muscular atrophy [ncbi.nlm.nih.gov]

Motor Neuron Disease

Some MNDs, such as ALS and some forms of spinal muscular atrophy, are fatal. [ninds.nih.gov]

A somewhat better prognosis is seen in progressive muscular atrophy, where patients live up to 25 years. [symptoma.com]

The Repository also banks subjects with MNDs that have known genetic causes, including Spinal Bulbar Muscular Atrophy (Kennedy’s Disease) and Spinal Muscular Atrophy. [coriell.org]

Primary Lateral Sclerosis

This locus had not been implicated in ALS or in hereditary spastic parapareses, spinal muscular atrophy, or spinal and bulbar muscular atrophy. [7] A genetically mediated [emedicine.com]

atrophy (PMA) and spinal muscular atrophies (SMAs) Upper and lower motor neurons - ALS ALS is the most common of the MNDs. [emedicine.com]

The traditional classification of MNDs is according to the affected cell types, as follows: Upper motor neurons alone - PLS Lower motor neurons alone - Progressive muscular [emedicine.com]

Amyotrophic Lateral Sclerosis

atrophy and related syndromes G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman] G12.1 Other inherited spinal muscular atrophy G12.2 Motor neuron disease G12.21 [icd10data.com]

Excluding lower motor neuron FA and FL cases, progressive muscular atrophy comprised 4% of the sample and had a prognosis similar to typical limb onset ALS. [ncbi.nlm.nih.gov]

Disorders of the lower motor neurone: the spinal muscular atrophies. In: Dubowitz V (Ed). [doi.org]

Multifocal Motor Neuropathy

In the first patient the symptoms were slowly progressive with bulbar muscle impairment, generalized weakness, muscular atrophy with cramps and fasciculations. [moh-it.pure.elsevier.com]

Control groups included CIDP, sporadic progressive spinal muscular atrophy (PSMA), and chronic idiopathic axonal polyneuropathy (CIAP). [doi.org]

atrophy. [doi.org]

Erb Muscular Dystrophy

At that time, the differentiation between the spinal muscular atrophies and weakness associated with central nervous system disorders and primary muscle disease had not been [emedicine.medscape.com]

A heterogeneous group of genetic disorders characterized by progressive muscular atrophy and muscle weakness beginning in the hands, the legs, or the feet. [icd10data.com]

atrophy • proximal weakness • onset of weakness is earlier in childhood • absent deep tendon reflexes and fasciculations • CPK levels are normal • pseudohypertrophy is absent [orthobullets.com]

Charcot-Marie-Tooth Disease

atrophy Peroneal muscular atrophy Charcot-Marie-Tooth disease、C-M-T [wikidata.org]

muscular atrophy muscular atrophy due to lesion of the spinal cord, as in spinal muscular atrophy. olivopontocerebellar atrophy any of a group of progressive hereditary disorders [medical-dictionary.thefreedictionary.com]

[…] slowly progressive degeneration of the muscles of the foot, lower leg, hand and forearm Charcot-Marie-Tooth disease CMT - Charcot-Marie-Tooth disease Charcot Marie Tooth muscular [wikidata.org]

Spinal Muscular Atrophy

[…] muscle atrophy survival motor neuron spinal muscular atrophy spinal muscular atrophies of childhood Spinal muscular atrophy Statements spinal-muscular-atrophy-pro Identifiers [wikidata.org]

Therapeutics development for spinal muscular atrophy. NeuroRx. 2006 ;3(2): 235 – 245. Google Scholar | Crossref | Medline 9. [doi.org]

Related Medscape Reference topics: Focal Muscular Atrophies Spinal Muscle Atrophy Spinal Muscular Atrophy Related Medscape resource: Resource Center Spinal Disorders Pathophysiology [emedicine.medscape.com]

Becker Muscular Dystrophy

BACKGROUND/PURPOSE: The purpose of this study was to explore the prevalence, nature and scope of pain in adolescents with spinal muscular atrophy and Duchenne and Becker muscular [ncbi.nlm.nih.gov]

Two other patients with a deletion of exon 47 showed progressive muscular atrophy and weakness; they were considered to be typical BMD in both clinical features and the type [ncbi.nlm.nih.gov]

muscular atrophy (SMA). [ncbi.nlm.nih.gov]

Adult Spinal Muscular Atrophy

[…] spinal muscular atrophy and juvenile asymmetric segmental spinal muscular atrophy. [symptoma.com]

[…] childhood Spinal muscular atrophies of childhood Spinal muscular atrophy Spinal muscular atrophy Spinal muscular atrophy Spinal muscular atrophy Spinal muscular atrophy Spinal [medical-dictionary.thefreedictionary.com]

Spinal muscular atrophy type 4, SMA type 4 Overview Adult-onset spinal muscular atrophy atrophy ( also known as Spinal muscular atrophy type 4, SMA type 4) is a disorder that [checkorphan.org]

Myotonic Dystrophy

New contributions to the theory of muscular atrophy in supranuclear paralysis especially in cerebral hemiplegia (Habilitationsschrift). [doi.org]

atrophy (most frequently involving the hands, forearms, and face), myotonia, frontal baldness, lenticular opacities, and testicular atrophy. [curlie.org]

By comparing symptoms, he was able to rule out Dejerine–Sottas syndrome and other spinal muscular atrophies that had already been classified. [doi.org]

Limb-Girdle Muscular Dystrophy

[…] by Duchenne.1,2 Other descriptions followed: familial atrophy of the pelvic girdle muscles (Leyden in 1876), scapulohumeral muscular atrophy (Erb in 1884), and myopathy with [dash.harvard.edu]

atrophy. [ncbi.nlm.nih.gov]

Spinal muscular atrophy. [patient.info]

Spinal Muscular Atrophy Type 3

spinal muscular atrophy treatment market, by disease type, 2015 - 2025 (USD Million) TABLE 7 U.S. spinal muscular atrophy treatment market, by treatment, 2015 - 2025 (USD [giikorea.co.kr]

17th October 2018 Conditions : Spinal Muscular Atrophy; Spinal Muscular Atrophy Type II; Spinal Muscular Atrophy Type 3 Intervention : Other: Observational study to examine [treat-nmd.eu]

atrophy. 3,4 In individuals with spinal muscular atrophy, degeneration of motor neurons in the spinal cord results in skeletal muscular atrophy and weakness commonly involving [togetherinsma-hcp.com]

Spinal Muscular Atrophy Type 1

atrophy type 1 with paradoxical breathing were placed on high-span PIP+PEEP when sleeping from the point of diagnosis of spinal muscular atrophy. [ncbi.nlm.nih.gov]

DESIGN: This study was a retrospective chart review of 16 patients with spinal muscular atrophy type 1 under 3 yrs of age consecutively referred for respiratory decompensations [ncbi.nlm.nih.gov]

Three children with spinal muscular atrophy type 1 underwent multiple intrathecal and intravenous infusions of mesenchymal stem cells. [ncbi.nlm.nih.gov]

Diabetic Amyotrophy

SMN1 and NAIP genes deletions in different types of spinal muscular atrophy in Khuzestan province, Iran. [connection.ebscohost.com]

Nerve conduction and EMG is used to rule out other conditions and diagnose diabetes muscular atrophy. [whydiabetes.blogspot.com]

Biros I, Forrest S (1999) Spinal muscular atrophy: Untangling the knot? J Med Genet 36: 1-8. [omicsonline.org]

Amyotrophic Lateral Sclerosis Type 5

[…] are affected before the distal parts. [6] Thus the pattern of muscular atrophy in our patient differed from that of typical ALS or progressive spinal muscular atrophy in that [neurologyindia.com]

Spinal Muscular Atrophy. A Timely Review. Arch Neurol. 2011;68:979-984. PubMed. Harding BN, Kariya S, Monani UR, et al. [neuropathology-web.org]

Amyotrophic Lateral Sclerosis Type 6

Progressive Muscular Atrophy (PMA) A progressive neurological disease in which the lower motor neurons deteriorate. [my.clevelandclinic.org]

Study of 962 patients indicates progressive muscular atrophy is a form of ALS. Neurology (2009). doi:10.1212/WNL.0b013e3181c1dea3 Visser, J. et al. [mda.org]

ALS Juvenile Spinal Muscular Atrophy, Included Kugelberg-Welander Disease Primary Lateral Sclerosis Progressive Bulbar Palsy, Included Spinal Muscular Atrophy, Type ALS Upper [rarediseases.org]

Amyotrophic Lateral Sclerosis Type 3

atrophy type IV) 등)이나 중금속 중독으로 인한 운동신경원질환으로 진단 받은 자 12) 본 임상시험 참여 4주 이내에 타 임상시험용 의약품을 투여 받거나 임상시험용 의료기기를 시술받은 자 13) 임신부, 수유부, 임신계획이 있거나 의학적으로 적절한 피임방법 외 경구용 (피임약,호르몬 이식, [cris.nih.go.kr]

Atrophy) 증상 뇌의 신경세포 특히 운동 신경원의 퇴행, 손발의 마비에 의한 운동장애, 근육쇠약, 호흡부전, 연하곤란(Dysphagia), 구음장애 관련 클리닉 질환정보 자세히 보기 [raredisease.snuh.org]

[…] are affected before the distal parts.[6] Thus the pattern of muscular atrophy in our patient differed from that of typical ALS or progressive spinal muscular atrophy in that [neurologyindia.com]

Postpoliomyelitis Syndrome

The rate of progression of post-poliomyelitis muscular atrophy is quite variable. [nejm.org]

atrophy, and poliomyelitis. [ncbi.nlm.nih.gov]

The symptoms and signs of PPS include new muscle weakness and atrophy (post-poliomyelitis progressive muscular atrophy; PPMA),as well as other musculoskeletal symptoms such [ci.nii.ac.jp]

Amyotrophic Lateral Sclerosis Type 9

muscular atrophy with pyramidal signs and some forms of hereditary distal motor neuropathy. [scielo.br]

Congenital Muscular Dystrophy

The objectives of this study were to determine the effects that routine daily home air-stacking maneuvers have on pulmonary function in patients with spinal muscular atrophy [ncbi.nlm.nih.gov]

atrophy, forms of Ehlers-Danlos syndrome, and Marfan syndrome (see these terms). [orpha.net]

Dystrophy - som.unm.edu/programs/opmd Spinal Muscular Atrophy - smaregistry.iu.edu [cmdir.org]

Amyotrophic Lateral Sclerosis Type 11

Generalized fasciculations were observed with no muscular atrophy or muscle weakness. Tendon reflexes were increased with bilateral Jacobson sign. [journals.lww.com]

muscular atrophy with pyramidal signs and some forms of hereditary distal motor neuropathy. [scielo.br]

atrophy (PMA) cannot be diagnosed as ALS until a minimum of 2 body regions are affected, but relevant genetic testing to rule out other motor neuron diseases should also [ajmc.com]

Myoadenylate Deaminase Deficiency

The diagnoses in the 13 patients were: polyneuropathy (n = 5), infantile spinal muscular atrophy (n = 3), congenital myopathy with type 2 fibre atrophy, facioscapulohumeral [ncbi.nlm.nih.gov]

He is currently involved in multiple clinical trials of novel genetic interventions for the treatment of spinal muscular atrophy and Duchenne muscular dystrophy. [books.google.com]

Myopathy, Endocrine

Muscular atrophy was more expressed than at TM patients. [scirp.org]

The muscular dystrophies The muscular dystrophies are a group of hereditary disorders characterized by progressive muscular atrophy and weakness. [britannica.com]

Electromyography Excludes primarily neurogenic processes (for example, spinal muscular atrophy). [patient.info]

Tay-Sachs Disease

atrophy. [ncbi.nlm.nih.gov]

They were first diagnosed as having atypical spinal muscular atrophy and, subsequently, spinocerebellar ataxia, but, recently, the diagnosis of late-onset Tay-Sachs disease [ncbi.nlm.nih.gov]

Other symptoms can include ataxia, progressive dementia, psychosis, a vegetative state in some cases, muscular atrophy, and muscular denervation. [molecularbasisdisease.pbworks.com]

Singleton Merten Syndrome

Atrophy, Scapuloperoneal OMIM:183020 Spinal Muscular Atrophy, Segmental OMIM:253400 Spinal Muscular Atrophy, Type III; SMA3 OMIM:253550 Spinal Muscular Atrophy, Type II; [informatics.jax.org]

Spinal muscular atrophy 1 Spinal muscular atrophy Ryukyuan type Spinal muscular atrophy type 1 with congenital bone fractures Spinal muscular atrophy type 2 Spinal muscular [personalizedcause.com]

Absent speech Lower limb spasticity Muscular hypotonia of the trunk Developmental regression Skin rash Irritability Spastic paraplegia Abnormality of the cerebral white matter [mendelian.co]

Triple A Syndrome

We present a 28 year-old woman with classical systemic features of triple A syndrome with prominent neurological dysfunctions/deficits, including distal muscular atrophy, [ncbi.nlm.nih.gov]

We report a 22-year-old female who presented with distal muscular atrophy and weakness in all limbs for two years. [ncbi.nlm.nih.gov]

CONCLUSIONS: The most consistent neurological manifestation of triple A syndrome in Japanese patients was progressive bulbospinal muscular atrophy with both upper and lower [ncbi.nlm.nih.gov]

Polyneuropathy

Neurologic examinations revealed diffuse muscular atrophy in his trunk, shoulders, upper limbs, thenar eminence and pelvic girdle. [jmedicalcasereports.biomedcentral.com]

Neuronal Peroneal Muscular Atrophy (HMSN II) Autosomal dominant inheritance is also the case with HMSN II. [lecturio.com]

atrophy & Responds to IVIg Infection Varicella Zoster ; Poliomyelitis ; Leprosy ; Lyme Disease Autoimmune Etiology Polyarteritis Nodosa Rheumatoid Arthritis Other Vasculitis [enotes.tripod.com]

Polymyositis

Kennedy disease or X-linked spinobulbar muscular atrophy is a rare X-linked recessive disorder with clinical features of slowly progressive atrophy and weakness of limb and [ncbi.nlm.nih.gov]

atrophy). [ncbi.nlm.nih.gov]

MDA addresses the muscular dystrophies, spinal muscular atrophy, ALS, Charcot-Marie-Tooth disease, myasthenia gravis, Friedreich's ataxia, metabolic diseases of muscle, and [brainfacts.org]