Muscular Atrophy, Fatigue & Hypothyroidism: Causes & Reasons

Possible Causes for Muscular Atrophy, Fatigue & Hypothyroidism

Health Diseases Adrenal Fatigue Addison’s Disease and Adrenal Fatigue Adrenal insufficiency, also known as Addison’s disease, is an autoimmune condition. [dummies.com]

Spontaneous resolution is rare, and the disease may be aggressive with soft-tissue sclerosis and muscular atrophy, bone involvement with resorptive osteolysis, or loss of [dermatologyadvisor.com]

A 57-year-old Caucasian woman with known autoimmune hypothyroidism diagnosed in 2006 presented to hospital with flu-like symptoms and circulatory collapse. [ncbi.nlm.nih.gov]

Dermatomyositis

Muscle weakness versus fatigue It may be easy to confuse muscle weakness with the general feeling of tiredness and weariness caused by fatigue. [dmpmandyou.com]

atrophy). [ncbi.nlm.nih.gov]

Hypothyroidism: like dermatomyositis, hypothyroidism can present with proximal weakness and elevated muscle enzymes. [ncbi.nlm.nih.gov]

Hyperthyroidism

If you have been diagnosed with hyperthyroidism, then you may have noticed some changes in your body, from unexplained weight loss to fatigue and tremors. [healthhub.sg]

Google Scholar Goolden AWG, Davidson M, Hoffenberg R: Myxedema preceding hyperthyroidism. [bmcresnotes.biomedcentral.com]

We report the case of a 33-year-old euthyroid woman who presented to our hospital with palpitation, hand tremor, fatigue, and excessive sweating after HSG. [ncbi.nlm.nih.gov]

Myasthenia Gravis

We quantified their fatigue using the modified fatigue impact scale (MFIS), the visual analogue fatigue scale (VAFS) and the fatigue severity scale (FSS) at the start of the [ncbi.nlm.nih.gov]

MDA addresses the muscular dystrophies, spinal muscular atrophy, ALS, Charcot-Marie-Tooth disease, myasthenia gravis, Friedreich's ataxia, metabolic diseases of muscle, and [brainfacts.org]

[…] predominance and a late peak in the 6th to the 8th decade with a male predominance.2 Myasthenia gravis is commonly associated with several other autoimmune disorders, including hypothyroidism [mdedge.com]

Graves Disease

Increased energy (hyperactivity) Fatigue Unexplained weight loss Trouble sleeping Inability to tolerate heat Trouble concentrating in school Diarrhea Fast, pounding heartbeat [cincinnatichildrens.org]

[…] wasting and disuse atrophy, not elsewhere classified 728.89 Other disorders of muscle, ligament, and fascia 729.9 Other and unspecified disorders of soft tissue 781.2 Abnormality [accessphysiotherapy.mhmedical.com]

Although conversion of Hashimoto's hypothyroidism into Graves' disease is exceptional in pregnancy, pregnant women with autoimmune hypothyroidism should ideally have their [ncbi.nlm.nih.gov]

Amyloidosis

After one year, her symptoms of fatigue became worse, and her proteinuria increased. [ncbi.nlm.nih.gov]

Differential diagnostics of an amiloidoz of heart is carried out with a hereditary dystonic lipidoz ( Fabri's disease ), a miksedematozny cardiomyopathy at a hypothyroidism [medicine-for-you.com]

Neoplasia - lymphangioma, hypothyroidism, acromegaly. [patient.info]

Steroid Myopathy

We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition. Last updated: May 12, 2019 [patientslikeme.com]

Palpation revealed symmetric muscular atrophy at the pelvic and shoulder girdles. No signs of effusion or ecchymosis were present. [jaoa.org]

Introduction: Major categories of endocrine myopathy include those associated with: Adrenal dysfunction (as in Cushing's disease or steroid myopathy); thyroid dysfunction (as in myxedema [annalsofian.org]

Myopathy, Endocrine

Adrenal insufficiency produces generalized weakness, muscle cramping, and fatigue in 50 per cent of patients. Some patients also develop hyperkalemic paralysis. [ncbi.nlm.nih.gov]

Muscular atrophy was more expressed than at TM patients. [scirp.org]

Hypothyroid myopathy What is hypothyroid myopathy? Hypothyroid myopathy is a muscle disease caused by deficient hormone production from the thyroid gland. [mda.org]

Late-Onset Pompe Disease

It is not uncommon for patients to experience muscle aches and cramps, as well as headaches and fatigue. [pompediseasenews.com]

Common misdiagnoses include adult-onset spinal muscular atrophy (SMA) and certain muscular dystrophies because of the selective involvement of the lower limbs. [ncbi.nlm.nih.gov]

Hypothyroidism in late-onset Pompe disease. [ncbi.nlm.nih.gov]

Myopathy and Diabetes mellitus

Fatigue is an abnormal feeling of weariness, tiredness, weakness, exhaustion or low energy. [diabeteshealthysolutions.com]

ATROPHIES & MOTOR NEURON DISEASES Spinal muscular atrophy, type I-IV (SMN1) Spinal muscular atrophy, autosomal dominant, proximal, adult-onset (VAPB) Spinal muscular atrophy [meduniwien.ac.at]

Possible causes of metabolic myopathy include: thyroid disease: hyperthyroidism hypothyroidism corticosteroid excess iatrogenic Cushing's disease Conn's syndrome biochemical [gpnotebook.co.uk]

Polyneuropathy

[…] often presents with symptoms that include tingling or numbness (beginning in the toes and fingers), weakness of the arms and legs, loss of deep tendon reflexes (areflexia), fatigue [ninds.nih.gov]

Neurologic examinations revealed diffuse muscular atrophy in his trunk, shoulders, upper limbs, thenar eminence and pelvic girdle. [jmedicalcasereports.biomedcentral.com]

[…] polyneuropathy a progressive lower motor neuron disease associated with hypothyroidism. idiopathic polyneuropathy immune-mediated polyneuropathy may occur in association [medical-dictionary.thefreedictionary.com]

Postpoliomyelitis Syndrome

My motivation is lower when I am fatigued. 2. Exercise brings on my fatigue. 3. I am easily fatigued. 4. Fatigue interferes with my physical functioning. 5. [books.google.com]

The rate of progression of post-poliomyelitis muscular atrophy is quite variable. [nejm.org]

[…] definition but to encourage polio survivors and their medical professionals to work together to find the causes of any symptom and provide treatment, i.e., medication for hypothyroidism [post-polio.org]

Pituitary Cushing Syndrome

Prognosis Untreated Cushing's disease can lead to severe complications such as excessive fatigue, intolerable headaches, nausea and vomiting, pathological bone fractures, [skullbaseinstitute.com]

RESULTS: Hirsutism, plethora facial, muscular weakness and muscular atrophy were more frequent in the MIC patients. [ncbi.nlm.nih.gov]

Detailed examinations revealed no disorders that could explain the pain other than concomitant Cushing's disease and central hypothyroidism. [ncbi.nlm.nih.gov]

Neonatal Hypotonia

[…] conditions that gradually cause the muscles to weaken, leading to increasing but variable levels of disability myasthenia gravis – a condition that causes weakness and increased fatigue [nhs.uk]

Peripheral (neuromuscular) causes were mainly represented by spinal muscular atrophy (6%) and myotonic dystrophy (4%). [ncbi.nlm.nih.gov]

[…] syndrome Spinal muscular atrophy Prader-Willi syndrome Tay-Sachs disease Trisomy 13 Other disorders that can lead to the condition include: Achondroplasia Being born with hypothyroidism [nlm.nih.gov]

Polymyositis

Muscle weakness versus fatigue It may be easy to confuse muscle weakness with the general feeling of tiredness and weariness caused by fatigue. [dmpmandyou.com]

Kennedy disease or X-linked spinobulbar muscular atrophy is a rare X-linked recessive disorder with clinical features of slowly progressive atrophy and weakness of limb and [ncbi.nlm.nih.gov]

In addition to raised creatinine phosphokinase (CPK) levels, his biochemical profile showed hypothyroidism. [ncbi.nlm.nih.gov]

Myoadenylate Deaminase Deficiency

The individuals with MDD fatigued after performing only 28% as much work as their non-MDD counterparts. [doi.org]

He is currently involved in multiple clinical trials of novel genetic interventions for the treatment of spinal muscular atrophy and Duchenne muscular dystrophy. [books.google.com]

Acute exertional rhabdomyolysis in hypothyroidism: the result of a reversible defect in glycogenolysis. Militar Med 1990;155:171-172. [pathology.leedsth.nhs.uk]

Dilated Cardiomyopathy Type 1J

He experienced fatigue with even minor activities such as walking up a flight of stairs, holding a clipboard, and filling a coffee pot with water. [bcmj.org]

atrophy type 1 Proximal spinal muscular atrophy type 2 Proximal spinal muscular atrophy type 3 Schizencephaly Senior-Loken syndrome Walker-Warburg syndrome WHIM syndrome [csbg.cnb.csic.es]

Alström's syndrome may also be associated with: [ 5 ] Hypothyroidism. Liver dysfunction. [patient.info]

Secondary Myopathy

1 Selected causes of asthenia and fatigue are listed in Table 1. 1 View/Print Table TABLE 1 Causes of Asthenia and Fatigue Addison’s disease Anemia Anxiety Chemotherapy [aafp.org]

[…] dystrophy, spinal muscular atrophy, and normal subjects. [link.springer.com]

Refractory Acute Kidney Injury Secondary to Hypothyroid-Induced Myopathy: A Contemporary Case Report Abstract This is a case report elucidating how severe hypothyroid-induced [journalmc.org]

Autoimmune Polyendocrine Syndrome

Addison disease can cause fatigue, muscle weakness, weight loss, low blood pressure, and changes in skin coloration. [counsyl.com]

In addition, the patient developed progressive muscular atrophy of unknown etiology at the beginning of the third decade, and is bedridden at the present time. [ncbi.nlm.nih.gov]

Moreover, analysis of the family tree showed direct transmission of the hypothyroid autoimmune thyroiditis/polyendocrinopathy-candidiasis-ectodermal dystrophy phenotype to [ncbi.nlm.nih.gov]

Proximal Myopathy with Extrapyramidal Signs

Fatigue Fatigue can be a nightmare; it is rarely used in the medical sense of an excessive failure of strength on repeated contraction. [jnnp.bmj.com]

Spinal muscular atrophy The clinical picture of spinal muscular atrophy (SMA) is highly variable and represents a continuum. [emedicine.medscape.com]

Play USMLE Audio MP3 10 05 Neonatal Hypothyroidism Below Begin 10 05 Neonatal Hypothyroidism Transcription What is another term for Neonatal hypothyroidism, starting with [boardprep.net]

Hoffmann Syndrome

We hereby present the case of a young male who presented with long-standing weakness and fatigue in the lower limb. [go.gale.com]

Related Medscape Drugs & Diseases topics: Focal Muscular Atrophies Spinal Muscle Atrophy Spinal Muscular Atrophy Related Medscape resource: Resource Center Spinal Disorders [emedicine.medscape.com]

This form of thyroid myopathy is rare and usually accompanies patients with severe and long-evolving hypothyroidism. [pesquisa.bvsalud.org]

Fatty Liver

Researchers also speculate that changes in brain chemistry and hormone production contribute to feelings of fatigue and exhaustion. [activebeat.com]

Patients with a previous diagnosis of hypothyroidism who are currently on synthetic T4 replacement were considered to be “hypothyroid”. [doi.org]

CASE SUMMARY: A 61-year-old obese man presented with jaundice, nausea, fatigue, and an unintentional weight loss 2 weeks following initiation of metformin. [ncbi.nlm.nih.gov]

Carcinomatous Myopathic Syndrome

There was no fatiguability/ptosis/opthalmoplegia to suggest myaesthenia gravis. [medicaleducationleeds.com]

atrophy, infantile Juvenile spinal muscle atrophy (Kugelberg-Welander) Kennedy Muscular atrophy disease Mitochondrial myopathy/MERRF Myhre Syndrome Distal muscular dystrophy [medchrome.com]

[…] storage myopathies: carnitine deficiency, carnitine palmityltransferase deficiency *The periodic paralyses *Myositis ossificans: generalized and local *Endocrine myopathies: hypothyroidism [itsmyositis.blogspot.com]

Multifocal Motor Neuropathy

This study is the first to show that activity-dependent conduction block plays a role in human disease by causing muscle fatigue. [ncbi.nlm.nih.gov]

Abstract Multifocal motor neuropathy (MMN) and progressive muscular atrophy (PMA) are associated with IgM monoclonal gammopathy or the presence IgM anti-GM1-antibodies. [ncbi.nlm.nih.gov]

Association of motor neuropathies or neuronopathies with thyroid disorders, such as hyperthyroidism, hypothyroidism or thyroid neoplasms has been rarely described. [ncbi.nlm.nih.gov]

Non-Dystrophic Myotonia

Usually this begins as tiredness or fatigue. It can progress to permanent changes if the medicines are not stopped. [patient.info]

View abstract Spinal muscular atrophy functional composite score: A functional measure in spinal muscular atrophy. Muscle Nerve. 2015 Dec; 52(6):942-7. [childrenshospital.org]

Sansone V Griggs RC Moxley III, RT Hypothyroidism unmasking proximal myotonic myopathy. [thelancet.com]

Hemochromatosis

When asked a series of questions to quantify level of fatigue 38.4% of patients had a fatigue severity score >36. [isge.ie]

The following genes are required for Invitae carrier screening and will be added to your order, CFTR (cystic fibrosis), SMN1 (spinal muscular atrophy), FMR1 (fragile X syndrome [invitae.com]

Irregular heart beat or heart attack Arthritis (osteoarthritis, osteoporosis) Cirrhosis of the liver or liver cancer Gall bladder disease Depression Impotence Infertility Hypothyroidism [hemochromatosis.org]

Celiac Disease

Bilateral non traumatic femoral neck fatigue fracture is a rare condition usually occurring secondary to medical conditions such as pregnancy, pelvic irradiation, corticosteroid [ncbi.nlm.nih.gov]

atrophy Headache Hypertransaminasemia Anemia Pubertal delay Extraintestinal symptoms A tendency towards lower clinical manifestations can be observed as age increases[ 4 [doi.org]

The presence of primary autoimmune hypothyroidism makes this case specific, since the inability for optimal substitution therapy with a high daily dose of levothyroxine provoked [ncbi.nlm.nih.gov]

Cystinosis

We ask about general symptoms (anxious mood, depressed mood, fatigue, pain, and stress) regardless of condition. Last updated: May 13, 2019 [patientslikeme.com]

The following genes are required for Invitae carrier screening and will be added to your order, CFTR (cystic fibrosis), SMN1 (spinal muscular atrophy), FMR1 (fragile X syndrome [invitae.com]

RESULTS: Eighteen (85.7%) had short stature, out of nine patients who reached pubertal age, five (55.5%) had pubertal delay, five patients (23.8%) had overt hypothyroidism [ncbi.nlm.nih.gov]

Menorrhagia

Treatment Principle Herb Formulas Points Clinical Manifestations Pale-red to normal Blood color Thin and watery Blood with clots Irregular menstruation Sallow complexion Fatigue [americandragon.com]

atrophy Spinal stenosis Spinocerebellar ataxia Spleen Splenic rupture Splenomegaly Spondylolisthesis Sports injuries Staphylococcal diseases Staphylococcal scalded skin syndrome [amboss.com]

@article{Ding2004HypovolaemicSC, title={Hypovolaemic shock caused by hypermenorrhoea with primary hypothyroidism.}, author={Dah-Ching Ding and T. [semanticscholar.org]

Thalassemia

In beta-thalassemia major (sometimes called Cooley anemia), people have severe symptoms of anemia, such as fatigue, weakness, and shortness of breath, and they may also have [merckmanuals.com]

atrophy, as well as a complete blood count and screening for thalassemias and hemoglobinopathies. [web.archive.org]

After exclusion of familial triglyceridemia and secondary causes (hypothyroidism, nephrotic syndrome, drugs etc.), a diagnosis of hypertriglyceridemia thalassemia syndrome [ncbi.nlm.nih.gov]