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93 Possible Causes for Muscular Atrophy, Weakness of the Intrinsic Hand Muscles

  • Motor Neuron Disease

    Some MNDs, such as ALS and some forms of spinal muscular atrophy, are fatal.[ninds.nih.gov] Muscle tone was normal throughout his body. Intrinsic hand muscles were atrophic.[jamanetwork.com] NTE-MND subjects exhibited progressive lower extremity spastic weakness that began in childhood and was later associated with atrophy of distal leg and intrinsic hand muscles[ncbi.nlm.nih.gov]

  • Cervical Spondylosis

    We found 19 patients with weakness and atrophy of the intrinsic hand muscles, and 13 patients with weakness proximal to the hand muscles to serve as a control group.[ncbi.nlm.nih.gov] The main clinical features are localized wasting and weakness of the extrinsic and intrinsic hand muscles, but not accompanied by either sensory loss or spastic quadriparesis[ncbi.nlm.nih.gov] The clinical and radiological findings were compared to a control group of patients with weakness of the arm or forearm muscles and similar mid-cervical spondylosis.[ncbi.nlm.nih.gov]

  • Primary Lateral Sclerosis

    This locus had not been implicated in ALS or in hereditary spastic parapareses, spinal muscular atrophy, or spinal and bulbar muscular atrophy. [7] A genetically mediated[emedicine.com] Patients may also notice a change in the appearance of their hands (due to wasting of the intrinsic muscles).[patient.info] atrophy (PMA) and spinal muscular atrophies (SMAs) Upper and lower motor neurons - ALS ALS is the most common of the MNDs.[emedicine.com]

  • Amyotrophic Lateral Sclerosis

    The patients were a 54-year-old man with progressive muscular atrophy who underwent removal of internal fixators in the arm and leg, and a 66-year-old woman with amyotrophic[ncbi.nlm.nih.gov] Or, the patient may find reduced finger dexterity, cramping, stiffness, and weakness or wasting of intrinsic hand muscles.[emedicine.com] BACKGROUND: Informal caregivers of patients with Amyotrophic Lateral Sclerosis (ALS) or Progressive Muscular Atrophy (PMA) face stressful demands due to severe impairments[ncbi.nlm.nih.gov]

  • Syringomyelia

    It results in neurological deficits that generally consist of segmental muscular weakness and atrophy accompanied by a dissociated sensory loss (loss of pain and temperature[medical-dictionary.thefreedictionary.com] Areflexia, muscle weakness, and atrophy results, commonly involving the hand intrinsics.[medscape.com] Syringomyelia is marked clinically by pain and PARESTHESIA, muscular atrophy of the hands, and analgesia with thermoanesthesia of the hands and arms, but with the tactile[fpnotebook.com]

  • Upper Motor Neuron Disease

    atrophy(PMA), Progressive bulbar palsy(PBP), MEPs were recorded from abductor pollicis brevis and abductor hallucis.[e-acn.org] O'Sullivan-McLeod syndrome (see this term), considered to be a variant of MA, presents with weakness in the intrinsic hand muscles.[orpha.net] atrophy and related syndromes G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman] G12.1 Other inherited spinal muscular atrophy G12.2 Motor neuron disease G12.21[icd10data.com]

  • Monomelic Amyotrophy

    Since its original description by Keizo Hirayama in 1959, "juvenile muscular atrophy of the unilateral upper extremity" has been described under many nomenclatures from the[ncbi.nlm.nih.gov] O'Sullivan-McLeod syndrome (see this term), considered to be a variant of MA, presents with weakness in the intrinsic hand muscles.[orpha.net] atrophy, predominantly on the left).[ncbi.nlm.nih.gov]

  • Progressive Bulbar Palsy

    […] term(s): Adult form spinal muscular atrophy Childhood form, type II spinal muscular atrophy Distal spinal muscular atrophy Juvenile form, type III spinal muscular atrophy[icd10coded.com] Patients may also notice a change in the appearance of their hands (due to wasting of the intrinsic muscles).[patient.info] Progressive muscular atrophy is a variety of ALS in which the neuron degeneration is most pronounced in the spinal cord.[britannica.com]

  • Myoadenylate Deaminase Deficiency

    The diagnoses in the 13 patients were: polyneuropathy (n 5), infantile spinal muscular atrophy (n 3), congenital myopathy with type 2 fibre atrophy, facioscapulohumeral myopathy[ncbi.nlm.nih.gov] The myopathy can also have different forms: (1) adult onset distal myopathy (distal leg weakness and intrinsic hand muscles); (2) subacute myopathy of the respiratory muscles[neuroweb.us] He is currently involved in multiple clinical trials of novel genetic interventions for the treatment of spinal muscular atrophy and Duchenne muscular dystrophy.[books.google.com]

  • Distal Hereditary Motor Neuropathy

    The syndrome in this family may be allelic to the juvenile distal spinal muscular atrophy first reported at this locus.[ncbi.nlm.nih.gov] […] peroneal then other muscle groups, milder weakness of hand intrinsics and eventually abnormal grip.[now.aapmr.org] atrophies (SMA).[ncbi.nlm.nih.gov]

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