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1,313 Possible Causes for mutagenic

  • Insect Bite

    To date, no cases of human toxicity, carcinogenicity, or mutagenicity have been reported.[travmed.com]

  • Malignant Neoplasm

    These secondary cancers may result (individually or in combination) from increased genetic susceptibility, the mutagenic effects of chemotherapy and/or radiation therapy,[ncbi.nlm.nih.gov] Causes of cancer Three major type of carcinogens Chemical carcinogenesis • Mutagens • Chemical carcinogenesis and their metabolism Physical carcinogenesis (radiation) • Ultraviolet[slideshare.net] Ionizing radiation is not a particularly strong mutagen. Residential exposure to radon gas, for example, has similar cancer risks as passive smoking.[en.wikipedia.org]

  • Pipobroman

    In order to avoid the mutagenic effects of radioactive phosphorous and alkylating agents, various European clinicians use pipobroman rather than hydroxyurea as single chemotherapeutic[ncbi.nlm.nih.gov] It could be used as an antineoplastic agent, but it might be very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions.[ebi.ac.uk] Alkylating agents form covalent cross-links with DNA thereby resulting in cytotoxic, mutagenic, and carcinogenic effects.[imed.rahnuma.com]

  • Radiation Therapy

    In select scenarios, this may result in the underprediction of acute and late toxicity risk (such as azoospermia, ovarian dysfunction, or increased lifetime mutagenic risk[ncbi.nlm.nih.gov] […] cumulative central-axis CBCT effective dose can approach or supersede the amount of radiation absorbed from a single treatment fraction, a theoretical increase of 3% to 5% in mutagenic[ncbi.nlm.nih.gov]

  • Human Immunodeficiency Virus

    Roche pioneered the dual target approach for HIV-1 viral load monitoring and continuously works to ensure assays can stay ahead of their highly mutagenic targets.[diagnostics.roche.com]

  • Trypanosoma Brucei

    To explore the function of this protein, we used a novel approach to make and screen numerous conditional null T. brucei bloodstream form cell lines that express randomly mutagenized[ncbi.nlm.nih.gov]

  • Tobacco

    Many of these compounds are found to have good absorption, solubility and permeability along with mutagenic and toxic properties.[ncbi.nlm.nih.gov] Areca nut, having aercoline (the major alkaloid) causes carcinogenicity, mutagenicity, and genotoxicity of oral mucosa through increased production of growth factors and corticotrophin-releasing[ncbi.nlm.nih.gov] Aldehydes are major TS carcinogens exerting dominant effect: Aldehydes induce mutagenic PdG adducts, impair DNA repair functions, and inhibit many procarcinogens in TS from[ncbi.nlm.nih.gov]

  • Eucommia

    The mutagenicity of urine from the Tochu tea-drinking group was much lower.[ncbi.nlm.nih.gov] Thus, the ingestion of Tochu tea may reduce human exposure to dietary mutagens.[ncbi.nlm.nih.gov] Again, the mutagenicity of urine collected from the Tochu tea-drinking group was much lower.[ncbi.nlm.nih.gov]

  • Alkylating Agent

    Thus, the killing and mutagenic actions of dacabazine can be dissociated by manipulating actions of these gene products.[ncbi.nlm.nih.gov] ‘Super-mutagens’, Nauka, Moscow (in Russian). Google Scholar 27. Bautz, E. and Freese, E. (1960), ‘On the mutagenic effect of alkylating agents’, Proc. Nat. Acad. Sci.[link.springer.com] […] seco-5alpha-androstan-17-oic-13,17-lactam-p-bis(2-chloro-ethyl)amino phenylacetate (AzaSteroidalEster, NSC-71964), is an alkylating agent with antineoplastic activity and mutagenic[ncbi.nlm.nih.gov]

  • Adenosine

    Furthermore, in vitro toxicity studies on compounds 5 and 6 did not reveal any mutagenicity (up to 100 μM), hepatotoxicity (up to 30 μM) or cardiotoxicity (up to 30 μM).[ncbi.nlm.nih.gov]

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