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572 Possible Causes for Mutation in the Hereditary Hemochromatosis Gene, Nocturnal Paroxysmal Dyspnea

  • Congestive Heart Failure

    Features due to left heart failure: Dyspnea, orthopnea and paroxysmal nocturnal dyspnea: These symptoms develop due to congestion of the lungs.[symptoma.com] The actuarial survival rates of persons who are homozygous for the mutation of the hemochromatosis gene C282Y have been reported to be 95%, 93%, and 66%, at 5, 10, and 20[doi.org] Major criteria: · Paroxysmal nocturnal dyspnea · Neck vein distention · Rales · Radiographic cardiomegaly (increasing heart size on chest radiography) · Acute pulmonary edema[medicalcriteria.com]

  • Heart Failure

    Major criteria: · Paroxysmal nocturnal dyspnea · Neck vein distention · Rales · Radiographic cardiomegaly (increasing heart size on chest radiography) · Acute pulmonary edema[medicalcriteria.com] The actuarial survival rates of persons who are homozygous for the mutation of the hemochromatosis gene C282Y have been reported to be 95%, 93%, and 66%, at 5, 10, and 20[doi.org] When the legs are elevated at night, the fluid redistributes centrally, causing pulmonary edema that results in orthopnea (dyspnea while laying flat) or paroxysmal nocturnal[healio.com]

  • Pulmonary Edema

    […] or comorbid paroxysmal nocturnal dyspnea and orthopnea are present, even in patients with preeclampsia.[ncbi.nlm.nih.gov] nocturnal dyspnea" if it causes you to wake up 1 to 2 hours after falling asleep and struggle to catch your breath.)[medlineplus.gov] In some patients, extreme edema may result in paroxysmal nocturnal dyspnea, although the pathogenesis of this conditions is not well-understood.[pathwaymedicine.org]

    Missing: Mutation in the Hereditary Hemochromatosis Gene
  • Cardiomyopathy

    Symptoms: Patients with cardiomyopathy will typically present with dyspnea, orthopnea, paroxysmal nocturnal dyspnea, bilateral edema, and fatigue.[symptoma.com] These symptoms of heart failure most commonly include dyspnea , orthopnea , paroxysmal nocturnal dyspnea , and fluid retention. How Is Postpartum Cardiomyopathy Treated?[verywellhealth.com] nocturnal dyspnea, and edema.[aafp.org]

    Missing: Mutation in the Hereditary Hemochromatosis Gene
  • Coronary Atherosclerosis

    Coronary artery disease (CAD) exhibits the rules of the multifactorial hereditary. Notwithstanding, the role of genetic factors in the prevalence of CAD is estimated very high. SIRT1 plays an athero-protective role and alterations in its expression have some important consequence in the metabolism, cholesterol, and[…][ncbi.nlm.nih.gov]

    Missing: Mutation in the Hereditary Hemochromatosis Gene
  • High Output Heart Failure

    Attacks of breathlessness severe enough to wake the patient frequently occur during sleep ( paroxysmal nocturnal dyspnea ).[medical-dictionary.thefreedictionary.com] Symptoms like dyspnea (difficulty in breathing), orthopnea (shortness of breath when lying flat) and paroxysmal nocturnal dyspnea (a severe increase in shortness of breath[ausmed.com] […] on exertion orthopnea paroxysmal nocturnal dyspnea fatigue pulmonary edema Physical exam cardiovascular exam pitting lower extremity edema jugular venous distention S3 sound[medbullets.com]

    Missing: Mutation in the Hereditary Hemochromatosis Gene
  • Aortic Valve Stenosis

    Other symptoms associated with AS are related to cardiac failure, such as paroxysmal nocturnal dyspnea, orthopnea, and dyspnea on exertion.[symptoma.com] The patient also presented dyspnea on minimal exertion, orthopnea, paroxysmal nocturnal dyspnea and edema of lower limbs. The patient denied fever.[web.archive.org] The clinical picture consists of the SAD triad: syncope upon physical exertion, angina and dyspnea.[symptoma.com]

    Missing: Mutation in the Hereditary Hemochromatosis Gene
  • Dilated Cardiomyopathy

    The following are the symptoms with which a patient may present: fatigue, orthopnea, dyspnea on exertion, paroxysmal nocturnal dyspnea, increasing edema, weight gain, or an[symptoma.com] At presentation she had dyspnea at rest, orthopnea and paroxysmal nocturnal dyspnea.[doi.org] nocturnal dyspnea) and/or reduced cardiac output (fatigue, shortness of breath, dyspnea, on exertion); arrhythmia and/or conduction system disease (CSD), including syncope[nature.com]

    Missing: Mutation in the Hereditary Hemochromatosis Gene
  • Mitral Valve Insufficiency

    Patients may be asymptomatic or may have manifestations like fatigue caused by reduced cardiac output, tachypnea or dyspnea, orthopnea, paroxysmal nocturnal dyspnea and hemoptysis[symptoma.com] nocturnal dyspnea), as well as symptoms of cardiogenic shock (i.e., shortness of breath at rest).[en.wikipedia.org] When the legs are elevated at night, the fluid redistributes centrally, causing pulmonary edema and resulting in orthopnea (dyspnea while lying flat) or paroxysmal nocturnal[healio.com]

    Missing: Mutation in the Hereditary Hemochromatosis Gene
  • Ischemic Cardiomyopathy

    Pulmonary congestion reduces when the patient is in erect position, it results in improvement in symptoms. [1],[2],[5] Paroxysmal nocturnal dyspnea Paroxysmal nocturnal dyspnea[explainmedicine.com] nocturnal dyspnea) Chest pain or pressure may be present along with the above symptoms Fatigue and weakness are commonly associated with cardiomyopathy Dizziness and lightheadedness[dovemed.com] […] patients in whom the additional volume cannot be pumped out by the left ventricle, there is a significant reduction in vital capacity and pulmonary compliance with resultant dyspnea[explainmedicine.com]

    Missing: Mutation in the Hereditary Hemochromatosis Gene

Further symptoms