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5,634 Possible Causes for Mutation in the PROK2 Gene, Small Testicular Volume, Weight Gain

  • Hypogonadotropic Hypogonadism

    gain or weight loss) Long-term (chronic) medical diseases, including chronic inflammation or infections Drug use, such as heroin or use or abuse of prescription opiate medicines[medlineplus.gov] Cryptorchid or maldescended testes and small testicular volume are clinical hallmarks of congenital hypogonadotropic hypogonadism (CHH) [ 1 ].[ijpeonline.biomedcentral.com] Homozygous loss-of function mutation in the PROK2 gene cause IHH and Kallmann syndrome [ 8 ].[omicsonline.org]

  • Kallmann Syndrome Type 4

    Rapid weight gain continues into adulthood; stature remains short and may be caused by growth hormone deficiency.[msdmanuals.com] Cryptorchid or maldescended testes and small testicular volume are clinical hallmarks of congenital hypogonadotropic hypogonadism (CHH) [ 1 ].[ijpeonline.biomedcentral.com] Homozygous loss-of function mutation in the PROK2 gene cause IHH and Kallmann syndrome [ 8 ].[omicsonline.org]

  • Klinefelter Syndrome

    gain, especially on the stomach or trunk tiredness and fatigue small penis disproportionately long arms and legs compared to the length of the body taller than average height[betterhealth.vic.gov.au] They concluded that the decline in serum testosterone may be related to the small testicular volume and Leydig cell loss near the scars after the procedures.[web.archive.org] The treatment of men with Klinefelter syndrome has been thought to be limited by the small testicular volume, extensive tubular sclerosis, and high FSH typically found for[dx.doi.org]

    Missing: Mutation in the PROK2 Gene
  • Overeating

    Weight Gain Unhealthy weight gain is one of the biggest dangers associated with eating too much.[healthyeating.sfgate.com] Overeating is the excess food consumed in relation to the energy that an organism expends (or expels via excretion), leading to weight gaining and often obesity.[en.wikipedia.org] Why that was so wasn’t clear, but Somers theorizes that it was because the participants were gaining weight, and therefore fat, during the study.[healthland.time.com]

    Missing: Mutation in the PROK2 Gene Small Testicular Volume
  • Sarcoidosis

    For individual end-points, weight gain (HR 2.04) and new hypertension (HR 3.36) were associated with any use of GC.[ncbi.nlm.nih.gov] Computed tomography detected a nodule in the middle lobe of the right lung, multiple small volume nodes in the retrocaval and left para-aortic regions, and enlarged bilateral[ncbi.nlm.nih.gov] gain Surgery In the rare situation when sarcoidosis has severely damaged your lungs, organ transplantation may be necessary.[brighamandwomens.org]

    Missing: Mutation in the PROK2 Gene
  • Kallmann Syndrome Type 3

    Rapid weight gain continues into adulthood; stature remains short and may be caused by growth hormone deficiency.[msdmanuals.com] Mean testicular volumes of HH patients were measured at the time of the diagnosis (solid circles) and at participation in the current study (small line).[journals.plos.org] Homozygous loss-of function mutation in the PROK2 gene cause IHH and Kallmann syndrome [ 8 ].[omicsonline.org]

  • Hypogonadotropic Hypogonadism Type 18

    gain or weight loss) Chronic medical diseases, including chronic inflammation or infections Certain medical conditions, such as iron overload[jeanbrownresearch.com] The clinical phenotype of our patients mirrored the severity of their hormonal deficiency with small prepubertal testicular volume and underdeveloped external genitalia.[journals.plos.org] Homozygous loss-of function mutation in the PROK2 gene cause IHH and Kallmann syndrome [ 8 ].[omicsonline.org]

  • Hypogonadotropic Hypogonadism Type 8

    The first patient (A) suffered from significant secondary symptoms, i.e. weight gain and skeletal pain, which had caused him to seek medical assistance.[thieme-connect.com] When the deficit is more severe and testicular volume is very small, FSH must be added [ 1 ].[em-consulte.com] Homozygous loss-of function mutation in the PROK2 gene cause IHH and Kallmann syndrome [ 8 ].[omicsonline.org]

  • Menopause

    Other physical changes Many women report some degree of weight gain along with menopause.[medicinenet.com] Fried foods and transfats are also tied to heart problems, weight gain, diabetes and cognitive impairments.[draxe.com] Menopause Can Hormone Therapy for Menopause Prevent Weight Gain?[everydayhealth.com]

    Missing: Mutation in the PROK2 Gene Small Testicular Volume
  • Ovarian Cyst

    If you have polycystic ovarian syndrome (multiple cysts in the ovaries) you may also experience weight gain and acne. For more information, see Useful links.[web.archive.org] An increase in the need to urinate Excessive bleeding during menstruation Irregular periods Unexplained weight gain Increase in the rate of hair growth Absence of menstrual[beatsofhealth.com] Other less frequent symptoms include: Pelvic pain Pain during sex Frequent need to urinate Unexplained weight gain Pain during your period Unusual vaginal bleeding Breast[yanhee.net]

    Missing: Mutation in the PROK2 Gene Small Testicular Volume

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