SCN5A polymorphism restores trafficking of a Brugada syndrome mutation on a separate gene..
[revespcardiol.org]
More than 500 mutations distributed in 10 genes have been described in this condition: KCNQ1, HERG, SCN5A, KCNE1, KCNE2, ANKB, KCNJ2, CACNA1, CAV3, and SCN4B.
[revespcardiol.org]
Long QT syndrome patients with mutations of the SCN5A and HERG genes have differential responses to Na+ channel blockade and to increases in heart rate.
[revespcardiol.org]