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108 Possible Causes for Mutation in the TTLL5 Gene, Onset in 2nd Decade of Life

  • Cone Rod Dystrophy
  • Diabetic Autonomic Neuropathy

    Clinical description Disease onset varies between the 2nd and 5th decade of life.[orpha.net]

    Missing: Mutation in the TTLL5 Gene
  • May-Thurner Syndrome

    Patients typically present with May-Thurner syndrome in their 2nd to 4th decades of life.[ncbi.nlm.nih.gov] The resultant endothelial damage and intraluminal spur formation can lead to iliac deep vein thrombosis and sudden-onset left-lower-extremity edema and pain.[ncbi.nlm.nih.gov]

    Missing: Mutation in the TTLL5 Gene
  • Dilated Cardiomyopathy

    , often in the 2nd and 3rd decades of life.[nature.com] Despite this, we have also more recently documented disease in a 70-year-old woman with onset at the age of 69 years, who was found to have a TNNT2 mutation shown to be likely[nature.com] […] progressing to LV dysfunction. 69 We 25, 29, 108 and others 30, 26, 27, 31 have also observed that TNNT2 mutations are commonly associated with DCM of early and aggressive onset[nature.com]

    Missing: Mutation in the TTLL5 Gene
  • Cavernous Hemangioma

    History The classic history for cavernous hemangioma is an adult, more often a women, in the 2nd to 6th decade of life with slowly progressive, painless proptosis.[eyewiki.aao.org] Patients usually report a gradual onset of symptoms over a period of 6 months to 2 years.[eyewiki.aao.org]

    Missing: Mutation in the TTLL5 Gene
  • Lupus Erythematosus

    The peak age at onset is the 2nd to 4th decades of life, but individuals of all ages can be affected (, 2 ).[pubs.rsna.org]

    Missing: Mutation in the TTLL5 Gene
  • Hereditary Angioedema Type 1

    (typically in the 2nd decade of life), predominance of facial swelling as compared to swellings of the extremities and sex bias.[genedx.com] […] or during the first pregnancy :Features that distinguish HAE type III from types I and II include: presence of normal C1 inhibitor activity levels, average later age of onset[genedx.com]

    Missing: Mutation in the TTLL5 Gene
  • Maturity-Onset Diabetes of the Young

    […] of diabetes in the 2nd–5th decades of life Insulin independence (although insulin may be required for optimal control) Frequent strong family history of diabetes (of any[diapedia.org] HNF4A,, IPF1, HNF1B, NEUROD1, CEL, ABCC8, KCNJ11, INS, PAX4, KLF11, BLK. [1] [2] [3] [4] [5] [6] [7] [8] [9] Clinical features shared by the different MODY subgroups are: Onset[diapedia.org]

    Missing: Mutation in the TTLL5 Gene
  • Acroosteolysis

    […] in the 2nd decade of life is associated with recurrent ulcers of the fingers and soles in the absence of neurological abnormalities.[rrnursingschool.biz] […] from Resnick and Niwayama 1995) the autosomal dominant acro-osteolysis of Schinz (OMIM 102400), slowly progressive osteolysis of the phalanges of the hands and feet with onset[rrnursingschool.biz]

    Missing: Mutation in the TTLL5 Gene
  • Lupus Cerebritis

    The peak age at onset is the 2nd to 4th decades of life, but individuals of all ages can be affected ( , 2 ).[pubs.rsna.org]

    Missing: Mutation in the TTLL5 Gene

Further symptoms