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1,948 Possible Causes for Mutation in the Tumor Protein p63 Gene, Palmar Hyperlinearity, Xeroderma

  • Atopic Dermatitis

    Particularly, xeroderma pigmentosum patients are characterized by a 1,000-fold increased susceptibility to sunlight-induced skin cancer ( 4 ).[doi.org] Among patients, reduced level of monomeric filaggrin and NMF correlated with the presence of FLG mutations and clinical phenotypes such as xerosis, palmar hyperlinearity and[ncbi.nlm.nih.gov] […] children Flexure lichenification in older children and adults Minor features Eyes Cataracts (anterior subcapsular) Keratoconus Infraorbital folds affected Facial pallor Palmar[aafp.org]

    Missing: Mutation in the Tumor Protein p63 Gene
  • Ichthyosis Vulgaris

    The main characteristics of IV are fine-scale on the arms and legs, palmar hyperlinearity, and keratosis pilaris.[ncbi.nlm.nih.gov] Abstract Ichthyosis vulgaris (IV) is the most common hereditary disorder of cornification in humans, characterized by generalized fine scaling of the skin, palmar hyperlinearity[ncbi.nlm.nih.gov] hyperlinearity and keratosis pilaris.[ncbi.nlm.nih.gov]

    Missing: Mutation in the Tumor Protein p63 Gene
  • Ichthyosis

    Ichthyosis, also called fish-skin disease, or xeroderma, a hereditary condition involving dryness and scaliness of the skin brought about by excessive growth of the horny[britannica.com] Palms and soles show accentuated creases and when affecting the palms this sign is referred to as palmar hyperlinearity or as “ichthyosis palms”.[medizin.uni-muenster.de] Types: xeroderma, xerodermia a mild form of ichthyosis characterized by abnormal dryness and roughness of the skin xeroderma pigmentosum a rare genetic condition characterized[vocabulary.com]

    Missing: Mutation in the Tumor Protein p63 Gene
  • Rapp-Hodgkin Syndrome

    CAUSES General: Rapp-Hodgkin syndrome (RHS) is believed to be caused by a mutation or defect in the TP73L gene, which produces several variants of the p73-like tumor protein[health24.com] […] pigmentosum ERCC4 Fanconi anemia, Xeroderma pigmentosum ERCC5 Xeroderma pigmentosum, Xeroderma pigmentosum/Cockayne syndrome ERCC6 De Sanctis-Cacchione syndrome, Xeroderma[genda.com.ar] Increased numbers and depth of skin lines on the palms may also occur (hyperlinearity). Hyperkeratosis may also affect the knees and elbows.[rarediseases.org]

  • Menopause

    J Theor Biol. 2017 Oct 7;430:229-236. doi: 10.1016/j.jtbi.2017.07.019. Epub 2017 Jul 22. Author information 1 Institute of Evolutionary Sciences, CNRS, IRD, EPHE CC 065, University of Montpellier, Place Eugène Bataillon, 34095 Montpellier cédex 05, France; Eco-Anthropology and Ethnobiology Lab, UMR 7206, 57 rue Cuvier,[…][ncbi.nlm.nih.gov]

    Missing: Mutation in the Tumor Protein p63 Gene Palmar Hyperlinearity
  • Chronic Alcoholism

    The concept of "structural plasticity" has emerged as a potential mechanism in neurodegenerative and psychiatric diseases such as drug abuse, depression, and dementia. Chronic alcoholism is a progressive neurodegenerative disease while the person continues to abuse alcohol, though clinical and imaging studies show[…][ncbi.nlm.nih.gov]

    Missing: Mutation in the Tumor Protein p63 Gene Palmar Hyperlinearity
  • Diabetes Mellitus

    Also called: Diabetes mellitus, DM Summary Diabetes is a disease in which your blood glucose, or blood sugar, levels are too high. Glucose comes from the foods you eat. Insulin is a hormone that helps the glucose get into your cells to give them energy. With type 1 diabetes, your body does not make insulin. With type 2[…][nlm.nih.gov]

    Missing: Mutation in the Tumor Protein p63 Gene Palmar Hyperlinearity
  • Chronic Kidney Insufficiency

    Chronic kidney insufficiency affects a significant number of individuals in the developed countries, particularly the United States. The progressive nature of the disease and a substantial reduction in the quality of life over the period of time are the primary reasons why an early diagnosis is crucial. Anemia,[…][symptoma.com]

    Missing: Mutation in the Tumor Protein p63 Gene Palmar Hyperlinearity
  • Congenital Ankyloblepharon

    The official name of the gene mutated in AEC syndrome is tumor protein 63 ( TP63 ).[rarediseases.org] […] pigmentosum ERCC4 Fanconi anemia, Xeroderma pigmentosum ERCC5 Xeroderma pigmentosum, Xeroderma pigmentosum/Cockayne syndrome ERCC6 De Sanctis-Cacchione syndrome, Xeroderma[genda.com.ar] Increased numbers and depth of skin lines on the palms may also occur (hyperlinearity). Hyperkeratosis may also affect the knees and elbows.[rarediseases.org]

  • Malabsorption Syndrome

    […] cobalamin absorption with megaloblastic anemia ) Fat-soluble vitamin deficiencies Vitamins S ymp toms Causes Sources Vitamin A Night blindness Retinopathy Xerophthalmia Xeroderma[amboss.com]

    Missing: Mutation in the Tumor Protein p63 Gene Palmar Hyperlinearity

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