Myalgia: Causes & Reasons

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Possible Causes for Myalgia

Viral Upper Respiratory Infection

Accompanying symptoms such as headache, myalgia and nasal obstruction also showed a tendency to decrease. [ncbi.nlm.nih.gov]

More severe viral upper respiratory infections also cause vomiting, nausea, diarrhea and abdominal pain, as well as myalgia, fatigue or malaise- more frequent in influenza [symptoma.com]

[…] secretions and stridor should raise suspicion for epiglottitis or pharyngeal abscess; influenza presents as a sudden illness characterized by high fever, severe headache, myalgia [medical-dictionary.thefreedictionary.com]

Polymyalgia Rheumatica

The headache and myalgia were improving with corticosteroid treatment; however, a trans-sphenoidal surgery was performed due to visual field loss. [ncbi.nlm.nih.gov]

Results: ESR, CRP, α2 globulin, pain, PGA, MST, myalgia, MT, and EUL showed significant improvement (p<0.0001) at week 24 compared with week 0. [ncbi.nlm.nih.gov]

Patients with undifferentiated ocular inflammatory syndromes should be questioned regarding arthralgias, myalgias and stiffness. [ncbi.nlm.nih.gov]

Rhabdomyolysis

Weakness, myalgia and tea-colored urine are the main clinical manifestations. [ncbi.nlm.nih.gov]

A previously healthy 37-year-old man presented with severe myalgia and dark urine after performing high-intensity exercise. [ncbi.nlm.nih.gov]

Eosinophilic Fasciitis

Eosinophilic fasciitis is a rare disease, but it must be considered in patients with adult myalgia. [ncbi.nlm.nih.gov]

It is characterized by painful swelling of the extremities, accompanied by rapid weight gain, fever and myalgia. [ncbi.nlm.nih.gov]

The illness was characterised by swelling of the extremities, skin changes, myalgia, and elevation of the peripheral blood eosinophils count and hypergammaglobulinemia. [ncbi.nlm.nih.gov]

Cryopyrin-Associated Periodic Syndrome

Nine patients (69%) reported myalgia. Six patients (46%) had papilledema and a further 2 (15%) had optic disc pallor. MRI brain scan was normal in all patients. [ncbi.nlm.nih.gov]

Conclusion: CAPS is a rare but treatable condition that may be encountered by neurologists in adult clinical practice since it can present with headache, myalgia, papilledema [n.neurology.org]

To identify the cause of disease in an adult patient presenting with recent-onset fevers, chills, urticaria, fatigue, and profound myalgia, who was found to be negative for [ncbi.nlm.nih.gov]

Acute Exertional Rhabdomyolysis

The myalgia improved progressively until it disappeared. [revistanefrologia.com]

Results: Among 43 players, 22 (51%) experienced rhabdomyolysis (peak creatine kinase range, 2434-42 000 U/L): 22 patients had upper arm myalgia; 12 were hospitalized; 3 experienced [stacks.cdc.gov]

A 62-year-old man was brought to the hospital with back pain and muscle weakness accompanied by myalgia. [blog.goo.ne.jp]

Microscopic Polyangiitis

We report a case of a 76-year-old woman, presenting with a persistent dry cough, subfebrility, arthralgia and myalgia, weight loss and a breast lesion. [ncbi.nlm.nih.gov]

The early clinical manifestations are indicative of systemic inflammation: fever, arthralgias, myalgias, fatigue, and/or loss of appetite. [orpha.net]

We describe the case of a 76-year-old man with microscopic polyangiitis (MPA) presenting with myalgia, abnormal muscle MRI findings and pulmonary fibrosis. [tandfonline.com]

Chronic Fatigue Syndrome

(Eosinophilia Myalgia Syndrome-EMS). [ncbi.nlm.nih.gov]

Individuals with fibromyalgia (FM) and/or chronic fatigue syndrome (CFS) report arthralgias and myalgias. [ncbi.nlm.nih.gov]

[…] debilitating fatigue appeared after therapeutic ingestion of products containing L-tryptophan and subsequent to the development of a transient rise in eosinophil count and severe myalgia [ncbi.nlm.nih.gov]

Tropical Myositis

The most common presentation was localised myalgia (100%), fever (96.7%) generalized myalgia (56.7%), arthralgia (40%), pain in abdomen (33.3%) and breathlessness (30%). [ncbi.nlm.nih.gov]

DD DVT Cellulitis Haematoma Rupture of Muscle/Tendon Polymyositis Leptospirosis(Diffuse myalgia wit severe LFT disturbances) 23. [slideshare.net]

Calcification and ossification of muscle, unspecified M62 Other disorders of muscle [See site code at the beginning of this chapter ] Excludes: cramp and spasm ( R25.2 ) myalgia [apps.who.int]

Polymyositis

We expose the case of a young woman (47 years old) who presented to the Pulmonology Clinic with fever, cough, purulent sputum, discrete myalgia, being diagnosed at that moment [ncbi.nlm.nih.gov]

This report highlights the case of a 30-year-old male who had severe myalgia and proximal muscle weakness. [ncbi.nlm.nih.gov]

Polymyositis is an inflammatory myopathy which, like SCD, may present with myalgia but is usually associated with proximal muscle weakness. [ncbi.nlm.nih.gov]

Upper Respiratory Infection

1, 2, 3, 4 Myalgia and fatigue Respiratory syncytial virus 1 (possibly 2) Human metapneumovirus 1 Coronaviruses 1 Picornaviruses Rhinoviruses (most common cause) > 100 types [atsu.edu]

[…] infection occurs producing a thickened yellow nasal discharge, watering eyes, mild fever, sore throat, headache, malaise (discomfort and uneasiness caused by an illness), myalgia [time-to-run.com]

A 44-year-old man with no significant medical history presents to his local urgent care center after 3 days of fevers, sore throat, rhinitis, coughing, and myalgia. [pulmonologyadvisor.com]

Eosinophilia Myalgia Syndrome

We describe a patient with eosinophilia-myalgia syndrome who developed incapacitating myalgias and peripheral eosinophilia responsive only to high dose corticosteroids. [ncbi.nlm.nih.gov]

Int J Occup Med Toxicol (in press) Google Scholar Centers for Disease Control (1989a) Eosinophilia-myalgia syndrome—New Mexico. [doi.org]

Eosinophilia-myalgia syndrome is an idiopathic disorder characterized by myalgia, especially of the extremities and peripheral eosinophilia. [ncbi.nlm.nih.gov]

Influenza

It is marked by inflammation of the nasal mucosa; the pharynx; and conjunctiva, and by headache and severe, often generalized, myalgia. [icd9data.com]

The influenza A virus has accounted for the majority of influenza infections in the 2017 to 2018 flu season, with the typical clinical presentation including fever, myalgias [ncbi.nlm.nih.gov]

It is marked by inflammation of the NASAL MUCOSA; the PHARYNX; and conjunctiva, and by headache and severe, often generalized, myalgia. [fpnotebook.com]

Systemic Juvenile Idiopathic Arthritis

Classical Presentation: Fever, salmon-colored rash, lymphadenopathy, myalgias, FERRITIN... ev negative ---------------- Juvenile idiopathic Arthritis, which has 3 forms 1) [usmleforum.com]

[…] lasting weeks to years in between Chronic: persistent and active, this type of ASD is most destructive to joints Other less common, but more serious symptoms can include myalgia [hss.edu]

Other characteristic manifestations include a prodromal sore throat, arthralgias, myalgias, weight loss, serositis, hepatomegaly (often with elevated hepatic enzymes), splenomegaly [rheumnow.com]

Muckle-Wells Syndrome

Myalgia, arthralgias and distal edema are very common. With age, patients develop eythematous band over the hands as well as digital clubbing. [orpha.net]

[…] recurrent fever (with malaise and chills), recurrent urticaria-like skin rash, sensorineural deafness, general signs of inflammation (eye redness, headaches, arthralgia/myalgia [orpha.net]

Adult-Onset Still Disease

Five weeks earlier, sore throat, fever, malaise, and myalgias had developed. Broad-spectrum antibiotic therapy was administered, without improvement. [blogs.nejm.org]

Since March 2017, he has had progressive fatigue, myalgias, rash, weight loss, diarrhea, and recurrent low-grade fever. [ncbi.nlm.nih.gov]

A 43-year-old man presented with a 3-week history of daily high-spiking fever, diffuse arthralgia and myalgia, sore throat, and a transient nonpruritic maculopapular rash. [ncbi.nlm.nih.gov]

Hantavirus Pulmonary Syndrome

The confirmed case involved a previously healthy young woman who died with signs and symptoms of acute respiratory insufficiency 5 days after presenting fever, myalgia and [ncbi.nlm.nih.gov]

This infection struck relatively young, healthy individuals, was characterized by fever, myalgias, respiratory failure, and a high mortality rate. [ncbi.nlm.nih.gov]

The typical prodrome consists of fever, chills, myalgia, headaches, and gastrointestinal symptoms, and can become complicated by acute respiratory distress syndrome (ARDS) [dph.georgia.gov]

Tumor Necrosis Factor Receptor 1-associated Periodic Syndrome

A characteristic feature of the myalgias is its pattern of centrifugal spread throughout the body. [ncbi.nlm.nih.gov]

The most distinctive features of an attack are fever and migratory myalgia and swelling in the extremities. The overlying skin is red and tender. [msdmanuals.com]

Notably, the patient's 26-year-old nephew had experienced similar symptoms since childhood, including migratory myalgias, cyclical chills, and night sweats. [ncbi.nlm.nih.gov]

Polyarteritis Nodosa

It is limited to the skin and has a recurrent and chronic course, possibly associated with fever, arthralgia, myalgia and neuropathy, but without visceral involvement. [ncbi.nlm.nih.gov]

[…] polyarteritis nodosa (CPAN) is characterized by a necrotizing vasculitis of small and medium-sized arteries in the skin, which can be associated with fever, arthralgia, myalgia [ncbi.nlm.nih.gov]

Myalgias. Mononeuropathy or polyneuropathy. New-onset diastolic blood pressure greater than 90 mm Hg. [patient.info]

McArdle Disease

He had no history of exercise-induced cramps, myalgias, or myoglobinuria. [ncbi.nlm.nih.gov]

He had no history of exercise‐induced cramps, myalgias, or myoglobinuria. [doi.org]

McArdle disease is a common metabolic disorder characterized by marked exercise intolerance, premature fatigue during exertion, myalgia, and cramps. [ncbi.nlm.nih.gov]

Ehrlichiosis

Infections often cause fever, myalgia, and hematological abnormalities, and sometimes mild elevation in transaminases, creatinine, and urinary protein. [ncbi.nlm.nih.gov]

[…] review emphasizes the need for a thorough history and physical examination in all patients who present with relatively non-specific complaints such as headaches, chills, myalgias [ncbi.nlm.nih.gov]

A 56-year-old man with a history of Wegener granulomatosis presented with 6 days of sinus congestion, fever, malaise, myalgias, episcleritis, and a morbilliform rash. [ncbi.nlm.nih.gov]

Familial Cold Autoinflammatory Syndrome Type 1

Definition A rare autosomal dominant systemic inflammatory disease characterized by recurrent episodes of maculopapular rash associated with arthralgias, myalgias, fever and [uniprot.org]

It is characterized by recurrent episodes of skin rash with arthralgias, myalgias, fever and chills. Typically those attacks occur after exposure to cold. [moldiag.com]

FCAS causes hives, fever, chills, myalgias, headache, stiffness and swelling, among other symptoms. “It's like you're freezing from the inside out,” says Rachel Doherty. [news-medical.net]

Relapsing Fever

The first episode is often accompanied by headaches, myalgias, arthralgias, neck stiffness, and nausea. [symptoma.com]

He complained of myalgia and secondarily presented fever. Blood smears revealed spirochetes later identified as Borrelia recurrentis. [ncbi.nlm.nih.gov]

Infected persons present with recurring episodes of high spiking fevers with accompanying headache, myalgias, and emesis. [nejm.org]

Nodular Nonsuppurative Panniculitis

Weber-Christian disease implies systemic involvement when the skin lesions are accompanied by arthralgia, myalgias, and abdominal pain. [accessanesthesiology.mhmedical.com]

Clinical findings Crops of subcutaneous nodules on the thighs, abdomen, arms and breasts, accompanied by fever, local inflammation, rheumatic complaints (arthritis, arthralgia, myalgia [medical-dictionary.thefreedictionary.com]

Inclusion term(s): Myofascial pain syndrome M79.10 Myalgia, unspecified site M79.11 Myalgia of mastication muscle M79.12 Myalgia of auxiliary muscles, head and neck M79.18 [icd10coded.com]

Marburg Virus Disease

[…] with AIDS Parainfluenza Pichinde virus disease Tacaribe virus disease Vesicular stomatitis Alagoas virus disease Viral encephalomyelocarditis Applies To Epidemic cervical myalgia [icd9data.com]

Disease onset is sudden, with fever, chills, headache, and myalgia. [doi.org]

RESULTS: A MHF case definition comprising (1) an epidemiological link or (2) the combination of myalgia or arthralgia and any hemorrhage could potentially serve as an alternative [ncbi.nlm.nih.gov]

Fibromyalgia

A 39-year-old woman with a 3-year history of a rounded face developed widespread myalgia. [ncbi.nlm.nih.gov]

Myalgia and arthralgia was observed in chronic EMS in the same incidence as in patients with FMS (81%). [ncbi.nlm.nih.gov]

Lingual myositis Lumbar myofascial pain syndrome Maxillary myositis Muscle pain Muscle pain, abdominal Muscle tension pain Musculoskeletal pain Myalgia Myalgia (muscle pain [icd9data.com]

Paroxysmal Rhabdomyolysis

Patients suffered generalized weakness, inability to walk, myalgia, muscle weakness, and dark urine. All patients appeared healthy in between episodes. [cags.org.ae]

RM and myalgia may be the dominating symptom in a few cases of LGMD2I [ 82 ]. [ojrd.biomedcentral.com]

Muscle aches and pain (myalgia), stiffness, and muscle weakness can occur with rhabdomyolysis, and is especially common with severe muscle damage. [whereincity.com]

Myoadenylate Deaminase Deficiency

Although most deficient subjects are asymptomatic, some suffer from exercise-induced myalgia suggesting a causal relationship between a lack of enzyme activity and muscle [ncbi.nlm.nih.gov]

CONCLUSION: MAD deficiency must be ruled out in every patient with exertional myalgia and increased CK which normalizes when asymptomatic. [pesquisa.bvsalud.org]

[…] to increase again with myalgias during exercise. [neurologia.com]

Typhus

KEYWORDS: Bhutan; Orientia tsutsugamushi eschar; chigger; conjunctival congestion; encephalitis/meningitis; eschar; larval mite; lymphadenitis; meningoencephalitis; myalgia [ncbi.nlm.nih.gov]

Abstract Scrub typhus is an acute infectious disease caused by Orienta tsutsugamushi, which is clinically manifested by fever, generalized lymphadenopathy, diffuse myalgia [ncbi.nlm.nih.gov]

High grade fever (90%), chills and rigors (68%), conjunctival suffusion (50%), body aches (43%), headache (41%), myalgias (37%), abdominal pain (21%), lymphadenopathy (17% [ncbi.nlm.nih.gov]

Leptospirosis

A 45-years-old male presented with 16 hours duration of myalgia, conjunctival suffusion, progressive flaccid quadriparesis, respiratory muscle weakness and dysphasia. [ncbi.nlm.nih.gov]

A 29-year-old male was transferred to our Renal Unit with fevers, myalgia and diarrhoeal illness. [ncbi.nlm.nih.gov]

All six patients were previously healthy paddy farmers presented with fever, myalgia and arthralgia. Four patients had abdominal pain, nausea and vomiting on admission. [ncbi.nlm.nih.gov]