Myalgia: Causes & Reasons

Warning: Do not use in emergencies, if pregnant, if under 18, or as a substitute for a doctor’s advice or diagnosis. Learn more

Possible Causes for Myalgia

Viral Upper Respiratory Infection

Accompanying symptoms such as headache, myalgia and nasal obstruction also showed a tendency to decrease. [ncbi.nlm.nih.gov]

More severe viral upper respiratory infections also cause vomiting, nausea, diarrhea and abdominal pain, as well as myalgia, fatigue or malaise- more frequent in influenza [symptoma.com]

[…] secretions and stridor should raise suspicion for epiglottitis or pharyngeal abscess; influenza presents as a sudden illness characterized by high fever, severe headache, myalgia [medical-dictionary.thefreedictionary.com]

Polymyalgia Rheumatica

The headache and myalgia were improving with corticosteroid treatment; however, a trans-sphenoidal surgery was performed due to visual field loss. [ncbi.nlm.nih.gov]

Results: ESR, CRP, α2 globulin, pain, PGA, MST, myalgia, MT, and EUL showed significant improvement (p<0.0001) at week 24 compared with week 0. [ncbi.nlm.nih.gov]

Patients with undifferentiated ocular inflammatory syndromes should be questioned regarding arthralgias, myalgias and stiffness. [ncbi.nlm.nih.gov]

Rhabdomyolysis

Weakness, myalgia and tea-colored urine are the main clinical manifestations. [ncbi.nlm.nih.gov]

A previously healthy 37-year-old man presented with severe myalgia and dark urine after performing high-intensity exercise. [ncbi.nlm.nih.gov]

Eosinophilic Fasciitis

In addition to systemic sclerosis, the prototype idiopathic fibrosing disorder, these conditions include the eosinophilia-myalgia syndrome, epidemic toxic oil syndrome, eosinophilic [ncbi.nlm.nih.gov]

Treating Eosinophilia-Myalgia Syndrome There is no cure for EMS, so treatment focuses on relieving symptoms. [verywell.com]

Eosinophilia-myalgia syndrome (EMS) is a rare disorder that causes inflammation in different parts of the body including muscles, skin, and lungs. [verywell.com]

Acute Exertional Rhabdomyolysis

The myalgia improved progressively until it disappeared. [revistanefrologia.com]

Results: Among 43 players, 22 (51%) experienced rhabdomyolysis (peak creatine kinase range, 2434-42 000 U/L): 22 patients had upper arm myalgia; 12 were hospitalized; 3 experienced [stacks.cdc.gov]

A 62-year-old man was brought to the hospital with back pain and muscle weakness accompanied by myalgia. [blog.goo.ne.jp]

Cryopyrin-Associated Periodic Syndrome

Nine patients (69%) reported myalgia. Six patients (46%) had papilledema and a further 2 (15%) had optic disc pallor. MRI brain scan was normal in all patients. [ncbi.nlm.nih.gov]

Conclusion: CAPS is a rare but treatable condition that may be encountered by neurologists in adult clinical practice since it can present with headache, myalgia, papilledema [n.neurology.org]

To identify the cause of disease in an adult patient presenting with recent-onset fevers, chills, urticaria, fatigue, and profound myalgia, who was found to be negative for [ncbi.nlm.nih.gov]

Eosinophilia Myalgia Syndrome

English eosinophilia-myalgia syndrome Human disease Eosinophilia myalgia syndrome EMS L-tryptophan induced EMS Severe muscle pain and abnormally high eosinophils Syndrome [wikidata.org]

Myalgia, muscle weakness, neuropathy, bladder dysfunction, myopathy, and fatigue frequently occur as well. [symptoma.com]

The term eosinophilia myalgia syndrome (EMS) was coined in 1989 after a cluster of cases with symptoms of incapacitating myalgias and eosinophilia were reported. [ncbi.nlm.nih.gov]

Muckle-Wells Syndrome

Myalgia, arthralgias and distal edema are very common. With age, patients develop eythematous band over the hands as well as digital clubbing. [orpha.net]

[…] recurrent fever (with malaise and chills), recurrent urticaria-like skin rash, sensorineural deafness, general signs of inflammation (eye redness, headaches, arthralgia/myalgia [orpha.net]

Polymyositis

We expose the case of a young woman (47 years old) who presented to the Pulmonology Clinic with fever, cough, purulent sputum, discrete myalgia, being diagnosed at that moment [ncbi.nlm.nih.gov]

This report highlights the case of a 30-year-old male who had severe myalgia and proximal muscle weakness. [ncbi.nlm.nih.gov]

Polymyositis is an inflammatory myopathy which, like SCD, may present with myalgia but is usually associated with proximal muscle weakness. [ncbi.nlm.nih.gov]

Tumor Necrosis Factor Receptor 1-associated Periodic Syndrome

A characteristic feature of the myalgias is its pattern of centrifugal spread throughout the body. [ncbi.nlm.nih.gov]

The most distinctive features of an attack are fever and migratory myalgia and swelling in the extremities. The overlying skin is red and tender. [msdmanuals.com]

Notably, the patient's 26-year-old nephew had experienced similar symptoms since childhood, including migratory myalgias, cyclical chills, and night sweats. [ncbi.nlm.nih.gov]

Microscopic Polyangiitis

We report a case of a 76-year-old woman, presenting with a persistent dry cough, subfebrility, arthralgia and myalgia, weight loss and a breast lesion. [ncbi.nlm.nih.gov]

The early clinical manifestations are indicative of systemic inflammation: fever, arthralgias, myalgias, fatigue, and/or loss of appetite. [orpha.net]

We describe the case of a 76-year-old man with microscopic polyangiitis (MPA) presenting with myalgia, abnormal muscle MRI findings and pulmonary fibrosis. [tandfonline.com]

Polyarteritis Nodosa

It is limited to the skin and has a recurrent and chronic course, possibly associated with fever, arthralgia, myalgia and neuropathy, but without visceral involvement. [ncbi.nlm.nih.gov]

[…] polyarteritis nodosa (CPAN) is characterized by a necrotizing vasculitis of small and medium-sized arteries in the skin, which can be associated with fever, arthralgia, myalgia [ncbi.nlm.nih.gov]

Myalgias. Mononeuropathy or polyneuropathy. New-onset diastolic blood pressure greater than 90 mm Hg. [patient.info]

Tropical Myositis

The most common presentation was localised myalgia (100%), fever (96.7%) generalized myalgia (56.7%), arthralgia (40%), pain in abdomen (33.3%) and breathlessness (30%). [ncbi.nlm.nih.gov]

DD DVT Cellulitis Haematoma Rupture of Muscle/Tendon Polymyositis Leptospirosis(Diffuse myalgia wit severe LFT disturbances) 23. [slideshare.net]

Calcification and ossification of muscle, unspecified M62 Other disorders of muscle [See site code at the beginning of this chapter ] Excludes: cramp and spasm ( R25.2 ) myalgia [apps.who.int]

Ehrlichiosis

Infections often cause fever, myalgia, and hematological abnormalities, and sometimes mild elevation in transaminases, creatinine, and urinary protein. [ncbi.nlm.nih.gov]

[…] review emphasizes the need for a thorough history and physical examination in all patients who present with relatively non-specific complaints such as headaches, chills, myalgias [ncbi.nlm.nih.gov]

A 56-year-old man with a history of Wegener granulomatosis presented with 6 days of sinus congestion, fever, malaise, myalgias, episcleritis, and a morbilliform rash. [ncbi.nlm.nih.gov]

Hantavirus Pulmonary Syndrome

The confirmed case involved a previously healthy young woman who died with signs and symptoms of acute respiratory insufficiency 5 days after presenting fever, myalgia and [ncbi.nlm.nih.gov]

This infection struck relatively young, healthy individuals, was characterized by fever, myalgias, respiratory failure, and a high mortality rate. [ncbi.nlm.nih.gov]

The typical prodrome consists of fever, chills, myalgia, headaches, and gastrointestinal symptoms, and can become complicated by acute respiratory distress syndrome (ARDS) [dph.georgia.gov]

Systemic Juvenile Idiopathic Arthritis

Classical Presentation: Fever, salmon-colored rash, lymphadenopathy, myalgias, FERRITIN... ev negative ---------------- Juvenile idiopathic Arthritis, which has 3 forms 1) [usmleforum.com]

[…] lasting weeks to years in between Chronic: persistent and active, this type of ASD is most destructive to joints Other less common, but more serious symptoms can include myalgia [hss.edu]

Other characteristic manifestations include a prodromal sore throat, arthralgias, myalgias, weight loss, serositis, hepatomegaly (often with elevated hepatic enzymes), splenomegaly [rheumnow.com]

McArdle Disease

He had no history of exercise-induced cramps, myalgias, or myoglobinuria. [ncbi.nlm.nih.gov]

He had no history of exercise‐induced cramps, myalgias, or myoglobinuria. [doi.org]

McArdle disease is a common metabolic disorder characterized by marked exercise intolerance, premature fatigue during exertion, myalgia, and cramps. [ncbi.nlm.nih.gov]

Adult-Onset Still Disease

Five weeks earlier, sore throat, fever, malaise, and myalgias had developed. Broad-spectrum antibiotic therapy was administered, without improvement. [blogs.nejm.org]

Since March 2017, he has had progressive fatigue, myalgias, rash, weight loss, diarrhea, and recurrent low-grade fever. [ncbi.nlm.nih.gov]

A 43-year-old man presented with a 3-week history of daily high-spiking fever, diffuse arthralgia and myalgia, sore throat, and a transient nonpruritic maculopapular rash. [ncbi.nlm.nih.gov]

Myoadenylate Deaminase Deficiency

CONCLUSION: MAD deficiency must be ruled out in every patient with exertional myalgia and increased CK which normalizes when asymptomatic. [pesquisa.bvsalud.org]

[…] to increase again with myalgias during exercise. [neurologia.com]

A diagnosis of tension myalgia or myofascial-type pain is often considered when no objective findings are seen in the evaluation. [ncbi.nlm.nih.gov]

Relapsing Fever

The first episode is often accompanied by headaches, myalgias, arthralgias, neck stiffness, and nausea. [symptoma.com]

He complained of myalgia and secondarily presented fever. Blood smears revealed spirochetes later identified as Borrelia recurrentis. [ncbi.nlm.nih.gov]

Infected persons present with recurring episodes of high spiking fevers with accompanying headache, myalgias, and emesis. [nejm.org]

Marburg Virus Disease

[…] with AIDS Parainfluenza Pichinde virus disease Tacaribe virus disease Vesicular stomatitis Alagoas virus disease Viral encephalomyelocarditis Applies To Epidemic cervical myalgia [icd9data.com]

Disease onset is sudden, with fever, chills, headache, and myalgia. [doi.org]

RESULTS: A MHF case definition comprising (1) an epidemiological link or (2) the combination of myalgia or arthralgia and any hemorrhage could potentially serve as an alternative [ncbi.nlm.nih.gov]

Nodular Nonsuppurative Panniculitis

Weber-Christian disease implies systemic involvement when the skin lesions are accompanied by arthralgia, myalgias, and abdominal pain. [accessanesthesiology.mhmedical.com]

Clinical findings Crops of subcutaneous nodules on the thighs, abdomen, arms and breasts, accompanied by fever, local inflammation, rheumatic complaints (arthritis, arthralgia, myalgia [medical-dictionary.thefreedictionary.com]

Inclusion term(s): Myofascial pain syndrome M79.10 Myalgia, unspecified site M79.11 Myalgia of mastication muscle M79.12 Myalgia of auxiliary muscles, head and neck M79.18 [icd10coded.com]

Chronic Fatigue Syndrome

(Eosinophilia Myalgia Syndrome-EMS). [ncbi.nlm.nih.gov]

Individuals with fibromyalgia (FM) and/or chronic fatigue syndrome (CFS) report arthralgias and myalgias. [ncbi.nlm.nih.gov]

[…] debilitating fatigue appeared after therapeutic ingestion of products containing L-tryptophan and subsequent to the development of a transient rise in eosinophil count and severe myalgia [ncbi.nlm.nih.gov]

Influenza

Myalgia Other names Muscle pain Specialty Rheumatology Myalgia, or muscle pain, is a symptom that presents with a large array of diseases. [en.wikipedia.org]

It is marked by inflammation of the nasal mucosa; the pharynx; and conjunctiva, and by headache and severe, often generalized, myalgia. [icd9data.com]

The influenza A virus has accounted for the majority of influenza infections in the 2017 to 2018 flu season, with the typical clinical presentation including fever, myalgias [ncbi.nlm.nih.gov]

Leptospirosis

A 45-years-old male presented with 16 hours duration of myalgia, conjunctival suffusion, progressive flaccid quadriparesis, respiratory muscle weakness and dysphasia. [ncbi.nlm.nih.gov]

A 29-year-old male was transferred to our Renal Unit with fevers, myalgia and diarrhoeal illness. [ncbi.nlm.nih.gov]

All six patients were previously healthy paddy farmers presented with fever, myalgia and arthralgia. Four patients had abdominal pain, nausea and vomiting on admission. [ncbi.nlm.nih.gov]

Fibromyalgia

Lingual myositis Lumbar myofascial pain syndrome Maxillary myositis Muscle pain Muscle pain, abdominal Muscle tension pain Musculoskeletal pain Myalgia Myalgia (muscle pain [icd9data.com]

Myalgia and arthralgia was observed in chronic EMS in the same incidence as in patients with FMS (81%). [ncbi.nlm.nih.gov]

A 39-year-old woman with a 3-year history of a rounded face developed widespread myalgia. [ncbi.nlm.nih.gov]

Churg-Strauss Syndrome

Very few reports described myalgia or weakness as the chief complaint. [ncbi.nlm.nih.gov]

After a few days in the hospital, fever subsided spontaneously and myalgia improved slightly with rest. [bmcmusculoskeletdisord.biomedcentral.com]

Eosinophilia-myalgia syndrome. C. Strongyloidiasis. D. Wegener's granulomatosis. E. Wells' syndrome. Discussion The answer is A: Churg-Strauss syndrome. [aafp.org]

Upper Respiratory Infection

1, 2, 3, 4 Myalgia and fatigue Respiratory syncytial virus 1 (possibly 2) Human metapneumovirus 1 Coronaviruses 1 Picornaviruses Rhinoviruses (most common cause) > 100 types [atsu.edu]

[…] infection occurs producing a thickened yellow nasal discharge, watering eyes, mild fever, sore throat, headache, malaise (discomfort and uneasiness caused by an illness), myalgia [time-to-run.com]

A 44-year-old man with no significant medical history presents to his local urgent care center after 3 days of fevers, sore throat, rhinitis, coughing, and myalgia. [pulmonologyadvisor.com]

Haff Syndrome

The most common causes of myalgia are overuse, injury or stress [1]. [wikidoc.org]

In any subjects with unexplained myalgia and rhabdomyolysis, seafood consumption should be included in the history. [mdpi.com]

According to the publication, the cases are suspected of a possible variant of epidemic myalgia. [flutrackers.com]

Human Granulocytic Ehrlichiosis

Cf Human monocytic ehrlichiosis. hu·man gran·u·lo·cyt·ic ehr·lich·i·o·sis (HGE) ( hū'măn gran'yū-lō-sit'ik er-lik'ē-ō'sis ) A febrile disease causing headache and myalgia [medical-dictionary.thefreedictionary.com]

CONCLUSIONS: In a patient with febrile illness occurring after a tick bite, a clinical report of chills, myalgia and arthralgia, and laboratory findings of elevated values [ncbi.nlm.nih.gov]

A 22-year-old multigravid female presented to the emergency department with a painful skin rash, high fever, and severe myalgias. [ncbi.nlm.nih.gov]