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556 Possible Causes for Myalgia, Proximal Muscle Weakness

  • Polymyositis

    From Wikidata Jump to navigation Jump to search rare idiopathic inflammatory myopathy characterized by symmetric proximal muscle weakness and elevated muscle enzymes edit[] We expose the case of a young woman (47 years old) who presented to the Pulmonology Clinic with fever, cough, purulent sputum, discrete myalgia, being diagnosed at that moment[] This report highlights the case of a 30-year-old male who had severe myalgia and proximal muscle weakness.[]

  • Childhood Dermatomyositis

    Abstract A 62-year-old woman presented to the emergency department with malaise, lethargy and proximal muscle weakness. She had a similar presentation in childhood.[] Dysphagia, myositis-specific or -related antibodies, factor VIII-related (von Willebrand) antigen, myalgia, muscle ultrasound and ulcerations had a median score of 4.[] Typical MRI and muscle biopsy changes were rated by all to be the most useful clinically relevant diagnostic criteria after proximal muscle weakness, characteristic skin rash[]

  • Dermatomyositis

    Later she developed progressive, symmetrical proximal muscle weakness.[] Within a month after the operation, myalgia and rash, including Gottron's papules, developed, and skeletal-muscle enzymes elevated, so she was diagnosed with probable DM according[] We diagnosed DM based on the presence of myalgia, Gottron's papules, and anti-aminoacyl-tRNA synthetase antibody positivity in the patient.[]

  • Polymyalgia Rheumatica

    Over time, disuse of muscle causes atrophy with proximal muscle weakness.[] The headache and myalgia were improving with corticosteroid treatment; however, a trans-sphenoidal surgery was performed due to visual field loss.[] It typically causes severe pain and stiffness in proximal muscles, without weakness or atrophy, and nonspecific systemic symptoms.[]

  • Glycogen Storage Disease Type 2

    Progressive proximal muscle weakness including major impairment of respiratory function dominates the picture.[] […] glycogen metabolism affecting muscle alone or together with other tissues, and they cause two main clinical syndromes: episodic, recurrent exercise intolerance with cramps, myalgia[] , myoglobinuria "Second wind" phenomenom rapid relief of fatigue and myalgia secondary to increase blood flow, improved free fatty acid delivery, and liver glucose utilization[]

  • Inclusion Body Myositis

    […] by proximal, upper-extremity weakness and later involvement of distal muscles groups.[] The unexpected appearance of myalgia during the course of painless inclusion body myositis must arouse the suspicion of an association of another inflammatory muscle disease[] Abstract We report a 17-year-old girl with an unusual neuromuscular disorder characterised by slowly progressive proximal muscle weakness whose muscle biopsy showed multiple[]

  • Hypokalemic Periodic Paralysis

    She developed significant proximal muscle weakness within 16 hours after the initial dose. Her serum potassium was 1.6 mEq/L.[] Postcritic myalgias were reported in 18 patients with Arg528His and one patient with Arg669His in whom the myalgias could last from several minutes to hours.[] Neurological examination revealed proximal muscle weakness and generalized hyporeflexia. There was no sensory abnormality and bowel or bladder involvement.[]

  • Vitamin D Deficiency

    Abstract A young woman with severe vitamin D deficiency presented with proximal muscle weakness, fragility fracture and pseudoarthrosis.[] Myalgias associated with statin therapy may also resolve with correction of vitamin D deficiency.[] Abstract We report a four-year-old African boy referred for proximal muscle weakness, fatigability and episodic limb pain.[]

  • Idiopathic Pulmonary Fibrosis

    To that end, the examiner should look for sclerodactily, scleroderma, proximal muscle weakness and telangiectasias. The history should exclude Raynaud's phenomenon.[] Constitutional symptoms, such as low-grade fever and myalgias, are uncommon. The classic sign of IPF is fine, dry, inspiratory crackles (Velcro crackles) at both bases.[] Some nonspecific, systemic symptoms like weight loss, fever, and myalgia also may be present.[]

  • Guillain-Barré Syndrome

    muscle weakness of the lower extremities.[] Suspected Zika virus disease was defined as a history of rash and 2 other Zika-related symptoms (fever, arthralgia, myalgia, or conjunctivitis).[] […] proportion of case-patients (83%) compared to controls (21%) reported an antecedent illness (OR 18.1, CI 6.9-47.5), most commonly characterized by rash, headache, fever, and myalgias[]

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