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24 Possible Causes for Myalgia, Sensorineural Hearing Loss May Be Presenting Feature

  • Cryopyrin-Associated Periodic Syndrome

    Characteristically Muckle-Wells syndrome is associated with the early development of progressive sensorineural hearing loss.[dermnetnz.org] Nine patients (69%) reported myalgia. Six patients (46%) had papilledema and a further 2 (15%) had optic disc pallor. MRI brain scan was normal in all patients.[ncbi.nlm.nih.gov] To identify the cause of disease in an adult patient presenting with recent-onset fevers, chills, urticaria, fatigue, and profound myalgia, who was found to be negative for[ncbi.nlm.nih.gov]

  • Muckle-Wells Syndrome

    Characteristically Muckle-Wells syndrome is associated with the early development of progressive sensorineural hearing loss.[dermnetnz.org] Myalgia, arthralgias and distal edema are very common. With age, patients develop eythematous band over the hands as well as digital clubbing.[orpha.net] The clinical features of the acute attacks of Muckle-Wells syndrome may include: Fever – not present in all cases, but when present is usually higher than in FCAS (39-40C)[dermnetnz.org]

  • CINCA Syndrome

    The CNS manifestations include chronic aseptic meningitis leading to brain atrophy, mental delay and sensorineural hearing loss.[ncbi.nlm.nih.gov] Myalgia is another frequent finding in patients with FMF (reported in 20% of cases).[emedicine.medscape.com] These manifest themselves in three principal ways: chronic meningitis, involvement of both the optic tract and eye, and sensorineural hearing loss.[en.wikipedia.org]

  • Susac Syndrome

    […] to retinal branch occlusions, and sensorineural hearing loss.[ncbi.nlm.nih.gov] Myalgia and/or arthralgia and urinary dysfunction may occasionally be observed.[orpha.net] hearing loss at low and medium frequencies 1-8 branch retinal artery occlusions leading to scotomata and vision distortion 1-8 All clinical features may not be present at[radiopaedia.org]

  • Primary Optic Atrophy

    Twenty per cent develop sensorineural hearing loss; other features are less common. 22. Behr syndrome Inheritance is AR; heterozygotes may have mild features.[slideshare.net] […] ataxia or weakness suggest demyelination In an older patient, previous history of transient visual loss, diplopia, temporal pain, jaw claudication, fatigue, weight loss and myalgia[patient.info] PAN can present as a systemic vasculitis with symptoms including fever, weight loss, myalgias, and arthralgias.[frontiersin.org]

  • Optic Atrophy

    Twenty per cent develop sensorineural hearing loss; other features are less common. 22. Behr syndrome Inheritance is AR; heterozygotes may have mild features.[slideshare.net] […] ataxia or weakness suggest demyelination In an older patient, previous history of transient visual loss, diplopia, temporal pain, jaw claudication, fatigue, weight loss and myalgia[patient.info] Presentation is in early childhood with reduced vision. Optic atrophy is diffuse. Prognosis is variable, with moderate to severe visual loss and nystagmus.[slideshare.net]

  • Pure Autonomic Failure

    The CNS manifestations include chronic aseptic meningitis leading to brain atrophy, mental delay and sensorineural hearing loss.[ojrd.biomedcentral.com] (tachycardia), excessive sweating (hyperhidrosis), perspiration depletion (anhidrosis), nerve pain or numbness (paresthesia or neuropathy), and joint pain (arthralgia or myalgia[clinicalposters.com] Chronic polyarthritis and alteration of the growth cartilage also may be present.[ojrd.biomedcentral.com]

  • Behr Syndrome

    Twenty per cent develop sensorineural hearing loss; other features are less common. 22. Behr syndrome Inheritance is AR; heterozygotes may have mild features.[slideshare.net] […] vesicles Associated with: Tubular aggregates Different from: Concentric laminated bodies in D-2-hydroxyglutaric aciduria Disease associations: Not specific Myotonia, Cramps, Myalgias[neuromuscular.wustl.edu] Diagnosis Code A83.9 Mosquito-borne viral encephalitis, unspecified 2016 2017 2018 2019 Billable/Specific Code Bornholm disease B33.0 ICD-10-CM Diagnosis Code B33.0 Epidemic myalgia[icd10data.com]

  • Maternally-Inherited Diabetes and Deafness

    Conclusions: MIDD syndrome should be considered in patients presenting with a clinical syndrome of sensorineural hearing loss and diabetes mellitus.[neurology.org] […] muscle cramp疼痛性筋痙攣 muscle phosphofructokinase deficiency筋ホスホフルクトキナーゼ欠損症 muscle soreness筋痛 muscle strength training筋力トレーニング muscular activity factor筋活動因子 muscular atrophy筋萎縮 myalgia[jds.or.jp] Additional features of mitochondrial disorders, such as myopathy, neuropathy, and myoclonus may be present. Valproic acid may be an effective treatment of myoclonus.[neurology.org]

  • Disproportionate Short Stature - Ptosis - Valvular Heart Lesions

    Mild spondyloepiphyseal dysplasia may also be present, and the hearing loss may be conductive and sensorineural.[nature.com] […] hypersensitivity to somatropin or excipients. 33 The most frequently observed adverse reactions include injection site reactions/rashes and fluid retention (ie, edema, arthralgia, myalgia[cmecorner.com] , fatigue, pruritus, pain in extremity, hypertension, chest pain, throat tightness, abdominal pain, dizziness, tachycardia, nasal congestion, diarrhea, edema peripheral, myalgia[clinicaladvisor.com]

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