Myelopathy: Causes & Reasons

Warning: Do not use in emergencies, if pregnant, if under 18, or as a substitute for a doctor’s advice or diagnosis. Learn more

Possible Causes for Myelopathy

Myelitis

Spondylotic myelopathy is the commonest cause of nontraumatic myelopathy. [ncbi.nlm.nih.gov]

[…] and systemic autoimmune disorders with myelopathy, as well as post-infectious and paraneoplastic myelopathies. [doi.org]

Inflammatory — Inflammatory Myelopathies — Inflammatory Myelopathy — Myelopathies, Inflammatory — Subacute Necrotising Myelitis — Myelitis, Subacute Necrotising — Necrotising [mesh.kib.ki.se]

Spinal Cord Infarction

BACKGROUND: Surfer’s myelopathy is a rare, acute, atraumatic myelopathy that occurs in novice surfers. [neurosurgerycns.wordpress.com]

Spondylosis, a normal aging process, is the most common cause of a cervical myelopathy ( Figs. 45-9 and 45-10 ; Box 45-2 ). [aibolita.com]

"Vascular myelopathies-vascular malformations of the spinal cord: presentation and endovascular surgical management". [en.wikipedia.org]

Spinal Cord Compression

The ideal treatment, therefore, depends on the situation, and the most acute treatment possible is necessary in patients presenting with myelopathy. [ncbi.nlm.nih.gov]

Symptoms Some of the symptoms of a myelopathy mimic other spinal problems. [spineuniverse.com]

We compared the neurological outcomes between radiotherapy and surgery in patients with metastatic spinal cord compression presenting with myelopathy. [ncbi.nlm.nih.gov]

Cerebral Angiitis

Most commonly seen are headache, stroke and encephalopathy but myelopathies, cranial nerve palsies, dementia and seizures are also recognized. 1, 2 Methods used in diagnosis [academic.oup.com]

Hermisson M, Klein R, Schmidt F, Weller M, Kuker W (2002) Myelopathy in primary Sjogren’s syndrome: diagnostic and therapeutic aspects. [link.springer.com]

[…] percent  Headache — 56 percent  Seizure — 30 percent  Stroke — 14 percent  Cerebral hemorrhage — 12 percent  Angiitis affecting the spinal cord usually presents as a myelopathy [slideshare.net]

Mucopolysaccharidosis Type 1

[…] the most serious skeletal finding because, in combination with ligamentous laxity and mucopolysaccharide deposition, it may result in atlantoaxial subluxation, cervical myelopathy [genedx.com]

Patients may develop myelopathy, but this condition does generally not manifest before puberty. [symptoma.com]

Atlantoaxial subluxation and stenosis of the spinal canal are observed in about a third of MPS-IH patients and results in spinal cord compression and early cervical myelopathy [symptoma.com]

Lathyrism

Ingestion of large amounts of poorly processed cassava roots is associated with the occurrence of an epidemic form of a noncompressive myelopathy (konzo) in African countries [medlink.com]

McCandless’s body was autopsied or whether spinal cord sections were included that might corroborate the presence of a toxic myelopathy. [ghostofcharcot.net]

[…] to muscular spasticity and paraplegia of lower extremities (Karmakar, 2007) accompanied by muscular atrophy (Park, 2009), making it one of the most dreadful toxic spastic myelopathies [isebindia.com]

Mucopolysaccharidosis

Significant inverse correlation was found between cervical myelopathy scores and neurological strength scores. [ncbi.nlm.nih.gov]

Enlarged perivascular spaces, white matter lesions, hydrocephalus, brain atrophy, cervical spinal canal stenosis with or without spinal cord compression and myelopathy, and [ncbi.nlm.nih.gov]

[…] younger sibling resulted in increased growth, an improved 6-minute walk test, less coarse face, slower progression of cardiac valve disease, and the absence of compressive myelopathy [ncbi.nlm.nih.gov]

Spinal Cord Injury

Subacute posttraumatic ascending myelopathy (SPAM) is a rare event that occurs after spinal cord trauma or ischemia. [ncbi.nlm.nih.gov]

We reported a patient with C5 [S(C5/C6)] ASIA Impairment Scale C SCI due to cervical myelopathy who presented CO2 retention when taking a therapeutic dosage of pregabalin. [ncbi.nlm.nih.gov]

To date, no traumatic myelopathy has ever been described in patients with HCU. [ncbi.nlm.nih.gov]

Primary Lateral Sclerosis

SNOMEDCT: 81211007 – Primary lateral sclerosis Differential Diagnosis & Pitfalls Amyotrophic lateral sclerosis Spinal muscular atrophy Hereditary spastic paraplegia Cervical myelopathy [visualdx.com]

[…] has arisen from the observation that many patients with PLS seemed ultimately to have different diseases such as ALS, spinal multiple sclerosis, or cervical spondylotic myelopathy [oxfordmedicine.com]

Radiation-induced myelopathy Type 1 Excludes myelopathy NOS ( G95.9 ) paralysis G12.20 ICD-10-CM Diagnosis Code G12.20 Motor neuron disease, unspecified 2016 2017 2018 2019 [icd10data.com]

Neurosarcoidosis

Paraneoplastic isolated myelopathy: Clinical course and neuroimaging clues. Neurology 2011;76:2089-95. [Figure 1], [Figure 2] [annalsofian.org]

Herein we describe three unusual patient presentations of neurosarcoidosis, one with optic neuritis, a second with hydrocephalus and a third with cervical myelopathy. [ncbi.nlm.nih.gov]

Various neurological complications of sarcoidosis commonly reported are cranial nerve palsies, aseptic meningitis, myelopathy and intracranial masses. [ncbi.nlm.nih.gov]

Systemic Lupus Erythematosus

We evaluated ambispectively those patients with SLE presenting with clinical myelopathy and corroborated with spinal MRI. [ncbi.nlm.nih.gov]

Myelopathy associated with systemic lupus erythematosus in 6 cases. Chin J Neuroimmunol Neurol (Chinese), 2006, 13(5):294–298 Google Scholar 18. [doi.org]

Multiple Sclerosis

Sexual dysfunction in selected neurologic disorders: hypothalamopituitary disorders, epilepsy, myelopathies, polyneuropathies, and sacral nerve lesions. [ncbi.nlm.nih.gov]

[…] with gadolinium of brain and spinal cord findings multiple focal demyelination scattered in brain and spinal cord asymmetric periventricular plaques Differential Cervical myelopathy [orthobullets.com]

Cavo-spinal phlebography in myelopathies. Stenoses of internal jugular and azygos veins, venous compressions and thromboses. [ncbi.nlm.nih.gov]

Herpes Zoster

However, MRI can be carried out in cases when there is development of encephalopathy and myelopathy. [symptoma.com]

• The absence of a rash or history of shingles does not exclude the possibility of varicella-zoster virus meningoencephalitis, myelopathy, or vasculopathy ( Gilden et al [medlink.com]

Myelitis is often characterized by myelopathy at a level consistent with the spinal segment affected by herpes zoster. [intechopen.com]

Hereditary ATTR Amyloidosis

[…] vomiting, pyrexia, hypersensitivity, decreased platelet count, cachexia (in 2 patients), arthralgia, myalgia, chorea, dementia, embolic stroke, intracranial hemorrhage, myelopathy [nejm.org]

Toxoplasmosis

Toxoplasmosis is considered to be a leading cause of death attributed to foodborne illness in the United States. More than 40 million men, women, and children in the U.S. carry the Toxoplasma parasite, but very few have symptoms because the immune system usually keeps the parasite from causing illness. However,[…] [cdc.gov]

Infectious Mononucleosis

Infectious mononucleosis is usually a self-limiting illness, but can be rarely associated with complications. A 17-year-old boy with Epstein-Barr virus related infectious mononucleosis and cold antibody-mediated autoimmune hemolytic anemia with incidentally noted multiple pulmonary nodules. Nodules regressed over the next[…] [ncbi.nlm.nih.gov]

Spinal Stenosis

The authors report two cases of thoracic spinal canal stenosis (SCS) and myelopathy. [ncbi.nlm.nih.gov]

Nonsurgical Treatment of Cervical Stenosis with Myelopathy Interventional treatments for cervical stenosis with myelopathy may include: Observation. [emoryhealthcare.org]

With myelopathy, surgery is often necessary at the beginning. [dukemedicine.org]

Cervical Osteoarthritis

Cervical spondylosis with cervical myelopathy, commonly referred to as cervical spondylotic myelopathy (CSM), refers to impaired function of the spinal cord caused by degenerative [spine-health.com]

Some patients will exhibit signs and symptoms of radiculopathy and myelopathy. [aafp.org]

We present a case of upper cervical myelopathy secondary to atlantoaxial instability and atlantodental osteoarthritis. [ncbi.nlm.nih.gov]

Radiculomyelopathy

(CSM), because the most significant risk factor for the development of myelopathy was preexisting spinal stenosis. [musculoskeletalkey.com]

TMS can aid physicians to:[9] Determine whether myelopathy exists Identify the level of the spinal cord where myelopathy is located. [en.wikipedia.org]

We report two cases of disabling myelopathy in association with pulmonary infection byMycobacterium kansasii andMycobacterium malmoense; the myelopathy is presumed to be a [thorax.bmj.com]

Cervical Spondylosis

This type of myelopathy hand they have termed "amyotrophic type of myelopathy hand." [ncbi.nlm.nih.gov]

[…] termed "Myelopathy hand," they have occasionally seen a different type of myelopathy hand characterized by muscle wasting and motor dysfunction in patients with cervical [ncbi.nlm.nih.gov]

Radiculopathy

[…] and symptoms of radiculopathy and myelopathy. [dynamicchiropractic.com]

Cervical myelopathy can involve your arms, hands, legs, and bowel and bladder function. [spinecenter.nm.org]

Myelopathy is the result of spinal cord compression. [orthogate.org]

Lumbar Spondylosis

Treatment of Lumbosacral Spondylosis without Myelopathy In majority of the cases of lumbosacral spondylosis without myelopathy, the treatment is non-operative. [epainassist.com]

[…] joint without myelopathy Spondylosis of lumbosacral joint WO myelopathy Applies To Lumbar or lumbosacral: arthritis osteoarthritis spondylarthritis ICD-9-CM Volume 2 Index [icd9data.com]

[…] site, without myelopathy 721.91 Spondylosis of unspecified site, with myelopathy M47.16 Other spondylosis with myelopathy, lumbar region M47.817 Spondylosis without myelopathy [accessphysiotherapy.mhmedical.com]

Anterior Spinal Artery Syndrome

WHY IS IT CALLED ANTERIOR MYELOPATHY? [medfriendly.com]

@article{3a364de4fe59438f9a76527b4dd2966b, title = "Anterior spinal artery syndrome presenting as cervical myelopathy in a patient with subclavian steal syndrome", author [jhu.pure.elsevier.com]

Spondylosis of cervical joint W myelopathy Spondylosis of cervical joint with myelopathy Stenosis of cervical (neck) spine with myelopathy Stenosis of cervical spine w myelopathy [icd9data.com]

Cervical Radiculitis

Cervical myelopathy can involve your arms, hands, legs, and bowel and bladder function. [nm.org]

If symptoms of cervical myelopathy are evident or progressing, you ought to be assessed by your NASS doctor. [spine.org]

Toe-heel walking is difficult in cervical myelopathy. [bjgp.org]

Spinal Demyelination

Izumo S (1989) The pathogenesis of HTLV-I associated myelopathy. Saishin Igaku 44:1603–1609 Google Scholar 10. [springerlink.com]

Some patients will exhibit signs and symptoms of radiculopathy and myelopathy. [aafp.org]

Another AVF with myelopathy and dilated vessels. [radiologyassistant.nl]

Paraparesis

Abstract: Human T lymphotropic virus type I (HTLV-I)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is chronic progressive myelopathy characterized by bilateral [eurekaselect.com]

HTLV-1-associated myelopathy/tropical spastic paraparesis) 1. [radiopaedia.org]

This study will use three different magnetic resonance imaging (MRI) techniques to study HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/STP)-a disease of slowly [clinicaltrials.gov]

Syringomyelia

Post-traumatic syringomyelia (cystic myelopathy): a prospective study of 449 patients with spinal cord injury. [jnnp.bmj.com]

Myelopathy

TMS can aid physicians to:[9] Determine whether myelopathy exists Identify the level of the spinal cord where myelopathy is located. [en.wikipedia.org]

Cause: Various factors give rise to myelopathy. [symptoma.com]

Cervical myelopathy is the most common type of myelopathy in adults above 55 years of age. [amboss.com]

Subacute Transverse Myelitis

Myelopathy work-up Acute intramedullary myelopathy Toxic myelopathy : Can occur hours after intranasal insufflation of heroin. [neuroweb.us]

[…] steroid nonresponsive myelopathy. [neurology.org]

Cervical spondylotic myelopathy is a common cause of myelopathy and may mimic transverse myelitis. [mayoclinic.pure.elsevier.com]

Transverse Myelitis

Cervical spondylotic myelopathy is a common cause of myelopathy and may mimic transverse myelitis. [ncbi.nlm.nih.gov]

Dennis A Nowak, Sebastian Mutzenbach and Hans-H Fuchs, Acute myelopathy. [doi.org]

The term of "acute myelopathy" is acute damage of spinal cord, without prejudging the nature of injury. [omicsonline.org]