Myelopathy: Causes & Reasons

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Possible Causes for myelopathy

Herpes Zoster

Myelitis is often characterized by myelopathy at a level consistent with the spinal segment affected by herpes zoster. [intechopen.com]

However, MRI can be carried out in cases when there is development of encephalopathy and myelopathy. [symptoma.com]

• The absence of a rash or history of shingles does not exclude the possibility of varicella-zoster virus meningoencephalitis, myelopathy, or vasculopathy ( Gilden et al [medlink.com]

Toxoplasmosis

We report a case of intrauterine infection by Toxoplasma gondii, Chikungunya and Zika viruses in a Colombian woman from the southern part of the country. The patient attended prenatal care in the second trimester of her pregnancy and she informed that in the first trimester she had presented with clinical[…] [ncbi.nlm.nih.gov]

Infectious Mononucleosis

The objective is to report a case of atypical acute infectious mononucleosis in a juvenile ankylosing spondylitis patient who was treated with infliximab. A 20-year-old man was hospitalized for the evaluation of lymphadenopathy and systemic symptoms. His symptoms developed at the eighth week of the infliximab[…] [ncbi.nlm.nih.gov]

Myelitis

Spondylotic myelopathy is the commonest cause of nontraumatic myelopathy. [ncbi.nlm.nih.gov]

[…] and systemic autoimmune disorders with myelopathy, as well as post-infectious and paraneoplastic myelopathies. [doi.org]

Abstract BACKGROUND: Inflammatory myelopathy is an inflammatory neurological disorder of the spinal cord (myelopathy). [ncbi.nlm.nih.gov]

Narrow Cervical Spinal Canal

BACKGROUND CONTEXT: A narrow cervical spinal canal (CSC) is a well-known risk factor for cervical myelopathy (CM). [ncbi.nlm.nih.gov]

[…] is often referred to more generally as cervical spondylosis with myelopathy or cervical spondylotic myelopathy. [spine-health.com]

Nonsurgical Treatment of Cervical Stenosis with Myelopathy Interventional treatments for cervical stenosis with myelopathy may include: Observation. [emoryhealthcare.org]

Spinal Stenosis

The authors report two cases of thoracic spinal canal stenosis (SCS) and myelopathy. [ncbi.nlm.nih.gov]

With myelopathy, surgery is often necessary at the beginning. [dukemedicine.org]

Results: Cervical myelopathy is a clinical syndrome due to dysfunction of the spinal cord. [doi.org]

Cervical Osteoarthritis

We present a case of upper cervical myelopathy secondary to atlantoaxial instability and atlantodental osteoarthritis. [ncbi.nlm.nih.gov]

Some patients will exhibit signs and symptoms of radiculopathy and myelopathy. [aafp.org]

Cervical spondylosis with cervical myelopathy, commonly referred to as cervical spondylotic myelopathy (CSM), refers to impaired function of the spinal cord caused by degenerative [spine-health.com]

Vitamin B12 Deficiency

His serum vitamin B12 levels were low and neuroimaging revealed myelopathy. [ncbi.nlm.nih.gov]

In this case report, we describe a 43 year old woman with pernicious anemia and myelopathy with atypical clinical features. [ncbi.nlm.nih.gov]

The patient was diagnosed as a case of non-compressive cervical myelopathy predominantly involving the posterior column due to vitamin B12 deficiency. [ncbi.nlm.nih.gov]

Radiculomyelopathy

(CSM), because the most significant risk factor for the development of myelopathy was preexisting spinal stenosis. [musculoskeletalkey.com]

We report two cases of disabling myelopathy in association with pulmonary infection byMycobacterium kansasii andMycobacterium malmoense; the myelopathy is presumed to be a [thorax.bmj.com]

We report two cases of disabling myelopathy in association with pulmonary infection by Mycobacterium kansasii and Mycobacterium malmoense; the myelopathy is presumed to be [research.ed.ac.uk]

Cervical Spondylosis

This type of myelopathy hand they have termed "amyotrophic type of myelopathy hand." [ncbi.nlm.nih.gov]

When presenting conjointly, degenerative cervical spondylosis and copper deficiency myelopathy may be difficult to differentiate providing the potential for mismanagement [ncbi.nlm.nih.gov]

Radiculopathy

[…] and symptoms of radiculopathy and myelopathy. [dynamicchiropractic.com]

Cervical myelopathy can involve your arms, hands, legs, and bowel and bladder function. [spinecenter.nm.org]

Overview Cervical myelopathy is a loss of function in your upper and lower extremities because of compression of the spinal cord within your neck. [nm.org]

Mucopolysaccharidosis

Significant inverse correlation was found between cervical myelopathy scores and neurological strength scores. [ncbi.nlm.nih.gov]

Enlarged perivascular spaces, white matter lesions, hydrocephalus, brain atrophy, cervical spinal canal stenosis with or without spinal cord compression and myelopathy, and [ncbi.nlm.nih.gov]

[…] younger sibling resulted in increased growth, an improved 6-minute walk test, less coarse face, slower progression of cardiac valve disease, and the absence of compressive myelopathy [ncbi.nlm.nih.gov]

Spinal Cord Infarction

BACKGROUND: Surfer’s myelopathy is a rare, acute, atraumatic myelopathy that occurs in novice surfers. [neurosurgerycns.wordpress.com]

Spondylosis, a normal aging process, is the most common cause of a cervical myelopathy ( Figs. 45-9 and 45-10 ; Box 45-2 ). [aibolita.com]

In this case report, we discuss the probable relationship between surfing and ischemic myelopathy. [ncbi.nlm.nih.gov]

Primary Lateral Sclerosis

SNOMEDCT: 81211007 – Primary lateral sclerosis Differential Diagnosis & Pitfalls Amyotrophic lateral sclerosis Spinal muscular atrophy Hereditary spastic paraplegia Cervical myelopathy [visualdx.com]

[…] has arisen from the observation that many patients with PLS seemed ultimately to have different diseases such as ALS, spinal multiple sclerosis, or cervical spondylotic myelopathy [oxfordmedicine.com]

[…] many reported patients seemed ultimately to have different diseases—for example, amyotrophic lateral sclerosis (ALS), spinal multiple sclerosis, or cervical spondylotic myelopathy [jnnp.bmj.com]

Lumbar Spondylosis

This condition can cause secondary myelopathy if the spondylosis results in cauda equina compression. Etiology The exact cause of lumbar spondylosis is unknown. [ehr.wrshealth.com]

Lumbar spondylosis without myelopathy. 09/20/2013. Author Disclosure Ameet Nagpal, MD Nothing to Disclose Alan Swearingen, MD Nothing to Disclose [now.aapmr.org]

[…] site, without myelopathy 721.91 Spondylosis of unspecified site, with myelopathy M47.16 Other spondylosis with myelopathy, lumbar region M47.817 Spondylosis without myelopathy [accessphysiotherapy.mhmedical.com]

Anterior Spinal Artery Syndrome

WHY IS IT CALLED ANTERIOR MYELOPATHY? [medfriendly.com]

@article{3a364de4fe59438f9a76527b4dd2966b, title "Anterior spinal artery syndrome presenting as cervical myelopathy in a patient with subclavian steal syndrome", author "Payam [jhu.pure.elsevier.com]

The presentation is usually with an acute and painful myelopathy with impaired bladder and bowel control. [ncbi.nlm.nih.gov]

Systemic Lupus Erythematosus

We evaluated ambispectively those patients with SLE presenting with clinical myelopathy and corroborated with spinal MRI. [ncbi.nlm.nih.gov]

Myelopathy associated with systemic lupus erythematosus in 6 cases. Chin J Neuroimmunol Neurol (Chinese), 2006, 13(5):294–298 Google Scholar 18. [doi.org]

Spinal Cord Compression

The ideal treatment, therefore, depends on the situation, and the most acute treatment possible is necessary in patients presenting with myelopathy. [ncbi.nlm.nih.gov]

It is well known that nerve root tumors developing in the spinal canal can be responsible for spinal cord compression leading to myelopathy and neurological deficits. [ncbi.nlm.nih.gov]

Symptoms Some of the symptoms of a myelopathy mimic other spinal problems. [spineuniverse.com]

Spinal Cord Injury

Subacute posttraumatic ascending myelopathy (SPAM) is a rare event that occurs after spinal cord trauma or ischemia. [ncbi.nlm.nih.gov]

We reported a patient with C5 [S(C5/C6)] ASIA Impairment Scale C SCI due to cervical myelopathy who presented CO2 retention when taking a therapeutic dosage of pregabalin. [ncbi.nlm.nih.gov]

To date, no traumatic myelopathy has ever been described in patients with HCU. [ncbi.nlm.nih.gov]

Multiple Sclerosis

Sexual dysfunction in selected neurologic disorders: hypothalamopituitary disorders, epilepsy, myelopathies, polyneuropathies, and sacral nerve lesions. [ncbi.nlm.nih.gov]

[…] with gadolinium of brain and spinal cord findings multiple focal demyelination scattered in brain and spinal cord asymmetric periventricular plaques Differential Cervical myelopathy [orthobullets.com]

Cavo-spinal phlebography in myelopathies. Stenoses of internal jugular and azygos veins, venous compressions and thromboses. [ncbi.nlm.nih.gov]

Cerebral Angiitis

Most commonly seen are headache, stroke and encephalopathy but myelopathies, cranial nerve palsies, dementia and seizures are also recognized. 1, 2 Methods used in diagnosis [academic.oup.com]

Hermisson M, Klein R, Schmidt F, Weller M, Kuker W (2002) Myelopathy in primary Sjogren’s syndrome: diagnostic and therapeutic aspects. [link.springer.com]

CNS manifestations include headache, strokes, seizures, myelopathy, and encephalopathy. [ncbi.nlm.nih.gov]

Cervical Radiculitis

Cervical myelopathy can involve your arms, hands, legs, and bowel and bladder function. [nm.org]

If symptoms of cervical myelopathy are evident or progressing, you ought to be assessed by your NASS doctor. [spine.org]

Toe-heel walking is difficult in cervical myelopathy. [bjgp.org]

Paraparesis

Abstract: Human T lymphotropic virus type I (HTLV-I)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is chronic progressive myelopathy characterized by bilateral [eurekaselect.com]

This study will use three different magnetic resonance imaging (MRI) techniques to study HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/STP)-a disease of slowly [clinicaltrials.gov]

HTLV-I, tropische spastische Lähmung - Klinische (Problembeschreibung) Myelopathie mit HTLV-I verbunden erfolgt meist in Form von langsam fortschreitende Brust Myelopathie [lekarzkatowice.blogspot.com]

Spinal Demyelination

Izumo S (1989) The pathogenesis of HTLV-I associated myelopathy. Saishin Igaku 44:1603–1609 Google Scholar 10. [springerlink.com]

Some patients will exhibit signs and symptoms of radiculopathy and myelopathy. [aafp.org]

I read with interest the article by Katz and Ropper1 on progressive necrotic myelopathy (PNM). [jamanetwork.com]

Subacute Myelo-Optico-Neuropathy

Journal Spinal Cord 49:182-5 (2011) DOI: 10.1038/sc.2010.68 Reference PMID: 23222550 Authors Igata A Title Subacute myelooptic neuropathy, beriberi, and HTLVIassociated myelopathy [genome.jp]

178 IGATA Akihiko 2012 "Subacute myelo-optic neuropathy, beriberi, and HTLV-I-associated myelopathy: elucidation of some neurological diseases in Japan," POLSKIE ARCHIWUM [arsvi.com]

Journal Spinal Cord 49:182-5 (2011) DOI:10.1038/sc.2010.68 Reference PMID:23222550 Authors Igata A Title Subacute myelooptic neuropathy, beriberi, and HTLVIassociated myelopathy [genome.jp]

Syringomyelia

Post-traumatic syringomyelia (cystic myelopathy): a prospective study of 449 patients with spinal cord injury. [jnnp.bmj.com]

Lathyrism

McCandless’s body was autopsied or whether spinal cord sections were included that might corroborate the presence of a toxic myelopathy. [ghostofcharcot.net]

Ingestion of large amounts of poorly processed cassava roots is associated with the occurrence of an epidemic form of a noncompressive myelopathy (konzo) in African countries [medlink.com]

[…] to muscular spasticity and paraplegia of lower extremities (Karmakar, 2007) accompanied by muscular atrophy (Park, 2009), making it one of the most dreadful toxic spastic myelopathies [isebindia.com]

Myelopathy

[13] See also[edit] Surfer's myelopathy References[edit] "Myelopathy" at American Journal of Neuroradiology "The Science of CSM". [en.wikipedia.org]

But myelopathy is rare and not reported so far. We report a 17 year old healthy male who developed myelopathy following cypermethrin ingestion. [ncbi.nlm.nih.gov]

A clear aetiology for surfer's myelopathy has not previous been described. [ncbi.nlm.nih.gov]

Subacute Transverse Myelitis

Myelopathy work-up Acute intramedullary myelopathy Toxic myelopathy : Can occur hours after intranasal insufflation of heroin. [neuroweb.us]

[…] steroid nonresponsive myelopathy. [neurology.org]

Cervical spondylotic myelopathy is a common cause of myelopathy and may mimic transverse myelitis. [mayoclinic.pure.elsevier.com]

Mucopolysaccharidosis Type 1

[…] the most serious skeletal finding because, in combination with ligamentous laxity and mucopolysaccharide deposition, it may result in atlantoaxial subluxation, cervical myelopathy [genedx.com]

Patients may develop myelopathy, but this condition does generally not manifest before puberty. [symptoma.com]

Joint stiffness, corneal clouding, umbilical hernia, abnormal facies, hepatomegaly, joint contractures, and cervical myelopathy occur. Death tends to be in their 20s. [patient.info]