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246 Possible Causes for Myocardial Contractility Decreased

  • Asthma

    Increased heart rate and contractility result in increased myocardial oxygen consumption and, conversely, reductions in heart rate and contractility lead to a decrease in[] By decreasing heart rate, myocardial contractility and afterload, β-adrenoceptor antagonists reduce myocardial workload and oxygen consumption at rest as well as during periods[] Their anti-ischemic effects are due primarily to a reduction in heart rate and cardiac contractility during periods of exertion or stress, which decreases myocardial oxygen[]

  • Psychogenic Hyperventilation

    […] quite markedly with hypocapnia lightheadedness & confusion CVS cerebral vasoconstriction (causing decreased cerebral blood flow) cardiac arrhythmias decreased myocardial[] contractility shift of the haemoglobin oxygen dissociation curve to the left (impairing peripheral oxygen unloading) slight fall in plasma [K ] COMPENSATION Compensation in[] […] decreased intracranial pressure (secondary to cerebral vasoconstriction) inhibition of respiratory drive via the central & peripheral chemoreceptors cerebral blood flow (CBF) decreases[]

  • Hyperkalemia

    […] excitability and contractility.[] Cessation of exercise results in a rapid decrease in plasma [K ], often to 3 mEq/l or less with intense exercise, that may be maintained for prolonged periods.[] […] the uptake of K from the blood by non-contracting tissues may be important in preventing plasma [K ] from rising to excessive levels that will impair skeletal muscle and myocardial[]

  • Diabetes Mellitus

    Severe metabolic acidosis can lead to impaired myocardial contractility, cerebral vasodilatation and coma, and several gastrointestinal complications ( 63 ).[] Bicarbonate therapy The use of bicarbonate in DKA is controversial ( 62 ) because most experts believe that during the treatment, as ketone bodies decrease there will be adequate[]

  • Chronic Obstructive Pulmonary Disease

    contractility and by decreasing afterload by reducing systemic vascular resistance. 44 45 Anaemic hypoxia is sensed in the aortic body, presumably owing to lower perfusion[] Acutely, the cardiovascular effects of hypoxaemia will tend to counter the impact of lower Ca o 2 on D o 2 by increasing cardiac output through increased heart rate and myocardial[]

  • Pulmonary Edema

    LV systolic dysfunction Systolic dysfunction, a common cause of CPE, is defined as decreased myocardial contractility that reduces cardiac output.[] Other causes of CPE often accompany mitral stenosis in acute CPE; an example is decreased LV filling because of tachycardia in arrhythmia (eg, atrial fibrillation) or fever[] The fall in cardiac output stimulates sympathetic activity and blood volume expansion by activating the renin-angiotensin-aldosterone system, which causes deterioration by decreasing[]

  • Acute Coronary Syndrome

    […] in heart rate, blood pressure, and myocardial contractility, improved diastolic filling, and, thereby, a decrease in myocardial workload.[] […] and contractility, leading to a reduction in myocardi al oxygen consumption, myocardial ischaemia and reinfarction [8].[] […] infarct size with early intravenous usage and can prevent arrhythmias. β-Blockers reduce myocardial workload and oxygen demand by reducing contractility, heart rate, and[]

  • Hypertrophic Cardiomyopathy

    contractility, decreased ventricular volume or decreased afterload One third of patients have the non obstructive form of HCM Diastolic dysfunction in HCM occurs due to abnormal[] Use beta-blockers and/or rate-limiting calcium channel blockers (usually verapamil ) to decrease myocardial contractility and slow the heart rate and thus prolong diastolic[] […] hypertrophy of the papillary muscles or anomalous papillary muscle insertion into the anterior mitral leaflet In another third, obstruction is labile, attributable to increased myocardial[]

  • Angina Pectoris

    Beta-blockers reduce myocardial oxygen demand and decrease heart rate and myocardial contractility.[] Specify therapeutic objective Stop an attack as soon as possible Reduce myocardial oxygen need by decreasing preload, contractility, heart rate or afterload iii.[]

  • Heart Failure

    Treatment for heart failure commonly involves reduction of the heart's workload, administration of drugs such as beta-blockers, digitalis to increase myocardial contractility[] The increase in afterload and myocardial contractility (known as inotropy) and the impairment in myocardial lusitropy lead to an increase in myocardial energy expenditure[] […] and cardiac output, salt-restricted diet, diuretics, angiotensin-converting enzymes to decrease afterload, and surgical intervention.[]

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