Myocardial Dysfunction: Causes & Reasons

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Possible Causes for Myocardial Dysfunction

Atrial Standstill

Diuresis with oral furosemide was initiated and combined with verapamil, the latter to treat possible myocardial ischemia and diastolic dysfunction. [nejm.org]

It is possible, however, that atrial systolic failure due to contractile dysfunction may occur in other myocardial infiltrative processes and may be detected in the future [nejm.org]

Low-Cardiac-Output Syndrome

Abstract Several cellular and molecular mechanisms have been implicated in the development of myocardial dysfunction and low cardiac output in pediatric patients undergoing [ncbi.nlm.nih.gov]

In the setting of transient postoperative myocardial dysfunction, even a moderate elevation of pulmonary pressure can result in heart dysfunction and circulatory collapse. [ncbi.nlm.nih.gov]

dysfunction. [unboundmedicine.com]

Apical Myocardial Infarction

J Am Coll Cardiol, 37(3): 705-10 [ 2 ][ GS ] Klocke, F.J., Sherman, A.J., Jain, A. (2000) Reversible myocardial dysfunction: Stunning, hibernation, or what?. [scindeks.ceon.rs]

Tako-tsubo-like left ventricular dysfunction with ST segment elevation: a novel cardiac syndrome mimicking acute myocardial infarction. [ncbi.nlm.nih.gov]

Myocardial viability: A clinical and scientific treatise, New York: Futura Publishing Company, str. 37-55 [ PM ] [ EČ ][ 1 ][ GS ] Kloner, R.A., Shook, T., Antman, E.M., Cannon [scindeks.ceon.rs]

Myocardial Fibrosis

Our case serves as a warning that primary myocardial fibrosis could be, in some cases, so extensive that it might lead to a rapidly aggravated myocardial dysfunction and eventual [ncbi.nlm.nih.gov]

According to the researchers, these results support the theory that progressive fibrofatty myocardial replacement is a substrate for myocardial dysfunction in DMD patients [musculardystrophynews.com]

Diastolic dysfunction is associated with microscopic myocardial fibrosis in SCA mice, but the cause of diastolic dysfunction in humans with SCA is unknown. [ncbi.nlm.nih.gov]

Takotsubo Cardiomyopathy

Takotsubo cardiomyopathy, apical ballooning syndrome or stress-induced cardiomyopathy is characterised by transient left ventricular dysfunction, mimicking myocardial infarction [ncbi.nlm.nih.gov]

Takotsubo cardiomyopathy (TTC), which is typically triggered by psychological or physical stress, is characterized by transient myocardial dysfunction affecting the left ventricular [ncbi.nlm.nih.gov]

Background: Catecholamine level surges may be associated with myocardial dysfunction, as observed in cases of septic shock, subarachnoid hemorrhage, respiratory failure, and [doi.org]

Papillary Muscle Dysfunction

Abstract Ischemic myocardial and papillary muscle dysfunction has considerable implication in newborn infants and children with normal or malformed hearts. [ncbi.nlm.nih.gov]

40 patients with prior myocardial infarction and no clinical evidence of papillary muscle dysfunction, and 20 normal subjects. [ncbi.nlm.nih.gov]

We hypothesized that papillary muscle perfusion pattern may explain the higher prevalence of posterior papillary muscle dysfunction after myocardial infarction. [ncbi.nlm.nih.gov]

Cardiogenic Shock

By definition, myocardial dysfunction from stunning eventually resolves completely. [www1.cgmh.org.tw]

dysfunction. [doi.org]

Myocardial pathology Cardiogenic shock is characterized by both systolic and diastolic dysfunction. [www1.cgmh.org.tw]

Postcardiac Injury Syndrome

Management of postcardiac arrest myocardial dysfunction. Curr Opin Crit Care. 2011 Jun;17(3):241-6. PMID: 21378558. [lifeinthefastlane.com]

The post-cardiac arrest syndrome includes systemic ischaemia/reperfusion response, post-cardiac arrest brain injury, postcardiac arrest myocardial dysfunction, and persistent [eurekaselect.com]

dysfunction Myocardial stunning – global hypokinesis Poor cardiac output Acute coronary syndromes Systemic ischaemia / reperfusion response Systemic inflammatory response [lifeinthefastlane.com]

Secondary Cardiomyopathy

dysfunction, and congestive heart failure. hypertrophic cardiomyopathy an increase in heart muscle weight, particularly of the left ventricle and often involving the interventricular [medical-dictionary.thefreedictionary.com]

Myocardial perfusion and fatty acid metabolism in patients with tako-tsubo-like left ventricular dysfunction. J Am Coll Cardiol. 2003;41:743-8. Medline 6. [revespcardiol.org]

Thus, myocardial dysfunction can cause a vicious cycle leading to more myocardial dysfunction in a process termed adverse ventricular remodeling, which is an important therapeutic [clevelandclinicmeded.com]

Primary Cardiomyopathy

dysfunction is part of a systemic disorder. [link.springer.com]

The same kind of reversible myocardial dysfunction is occasionally encountered in patients with intracranial haemorrhage or other acute cerebral accidents (neurogenic myocardial [academic.oup.com]

Myocardial Tumor

Abstract Myocardial tumor necrosis factor-alpha (TNF-alpha), a proinflammatory cytokine, is a critical inducer of myocardial dysfunction in sepsis. [ncbi.nlm.nih.gov]

Conclusions: These data suggest that Losartan may mitigate tumor-induced myocardial dysfunction and inflammation. [epublications.marquette.edu]

dysfunction 41. [slideshare.net]

Cardiac Dilatation

As a primary myocardial disorder, the myocardial dysfunction of dilated cardiomyopathy occurs in the absence of other disorders that can cause dilated myocardium, such as [merckmanuals.com]

dysfunction (ejection fraction < 40%). [lifeinthefastlane.com]

Drug-Induced Cardiomyopathy

Introduction Prolonged use of hydroxychloroquine (HCQ) has been implicated in the development of conduction disturbances and myocardial dysfunction. 1 We report a case of [circheartfailure.ahajournals.org]

The reduction of the contractile support of myocardial cells can explain the possible myocardial dysfunction. [romj.org]

Dilated Cardiomyopathy

BACKGROUND: To investigate the association between diabetic retinopathy (DR) and myocardial dysfunction in patients with type 2 diabetes and dilated cardiomyopathy (dCMP). [ncbi.nlm.nih.gov]

As a primary myocardial disorder, the myocardial dysfunction of dilated cardiomyopathy occurs in the absence of other disorders that can cause dilated myocardium, such as [merckmanuals.com]

Dilated Cardiomyopathy Type 1R

dysfunction (ejection fraction < 40%). [lifeinthefastlane.com]

The cardiomyopathies represent a diverse group of conditions whose final common pathway is myocardial dysfunction. [clevelandclinicmeded.com]

Aortic Valve Insufficiency

Echocardiographic predictors of early postsurgical myocardial dysfunction in pediatric patients with aortic valve insufficiency. Pediatric Cardiology, 34 (6), 1335–1343. [medical-dictionary.thefreedictionary.com]

More objective markers of impending myocardial dysfunction are needed, but these remain elusive. [content.onlinejacc.org]

Most findings in patients with aortic valve insufficiency are related to LV volume overload and eventual myocardial dysfunction. [emedicine.com]

Acute Myocarditis

We report a case where strain Doppler echocardiography was able to identify longitudinal segmental myocardial dysfunction derived from edema in acute phase of myocarditis. [ncbi.nlm.nih.gov]

RECENT FINDINGS: Newer methods such as strain and strain rate imaging using speckle tracking have emerged as an adjunctive echocardiographic parameter of myocardial dysfunction [ncbi.nlm.nih.gov]

-27.4 ± 3.4%, RS: 28.9 ± 8.5% vs. 32.4 ± 7.4%; P CONCLUSIONS: FT CMR myocardial strain analysis might serve as a new tool for assessment of myocardial dysfunction in the [ncbi.nlm.nih.gov]

Left Ventricular Dilatation

OBJECTIVE: Whether cardiac ventricles can acutely dilate during septic myocardial dysfunction. [ncbi.nlm.nih.gov]

dysfunction (ejection fraction < 40%). [lifeinthefastlane.com]

Ischemic Cardiomyopathy

[…] infarctions, leading to improved patient survival, however often leading to increased morbidity due to left ventricular (LV) remodelling and chronic myocardial dysfunction [heart.bmj.com]

CAD, myocardial ischemia, scarring, and ventricular dysfunction are the main features of ICM. [symptoma.com]

Dilated Cardiomyopathy Type 2B

Dilated Cardiomyopathy Overview Dilated cardiomyopathy (DCM) is a myocardial disease characterised by ventricular dilatation and global myocardial dysfunction (ejection fraction [litfl.com]

The cardiomyopathies represent a diverse group of conditions whose final common pathway is myocardial dysfunction. [clevelandclinicmeded.com]

Myocardial Contusion

Abstract Myocardial contusion, (traumatic myocardial dysfunction) is a relatively common complication of blunt trauma. The diagnosis is often elusive. [ncbi.nlm.nih.gov]

Abstract Because myocardial dysfunction may result from severe trauma, the author assessed, prospectively, left and right ventricular function in 25 patients who had sustained [ncbi.nlm.nih.gov]

TOE has proved sensitive in detecting ventricular dysfunction but this is not specific for myocardial injury. [emj.bmj.com]

Incessant Infant Ventricular Tachycardia

While indications for therapy cannot be determined from this study, lack of symptoms or myocardial dysfunction suggests that therapy may not be necessary. [unboundmedicine.com]

Although indications for therapy cannot be determined from this study, the lack of symptoms or myocardial dysfunction suggests that therapy may not be necessary in this narrowly [ncbi.nlm.nih.gov]

Tricuspid Valve Insufficiency

dysfunction, perhaps by affecting papillary muscle specifically. [pediatrics.aappublications.org]

Although dysfunction secondary to myocardial infarction is less common than occurs with the mitral valve, the underlying cause must be determined in order to plan treatment [emedicine.medscape.com]

[…] wave abnormalities on the ECG, and spontaneous resolution of the transient tricuspid insufficiency strongly suggest that this syndrome is secondary to a reversible form of myocardial [pediatrics.aappublications.org]

Cardiac Dyskinesia

If you think you have an arrhythmia, consult a physician. ...Read more 11 What is myocardial dysfunction? [healthtap.com]

Stunning is defined as postischemic myocardial dysfunction that persists despite restoration of normal blood flow. [radiologyassistant.nl]

The scar resulting from myocardial infarction may further contribute to left ventricular dysfunction by restricting filling or by creating an aneurysm (see definition myocardial [rjmatthewsmd.com]

Myocarditis due to Radiation

dysfunction Ischemic myocardial dysfunction Microcephalus cardiomyopathy syndrome Nonischemic congestive cardiomyopathy Nonsenile cataract Primary dilated cardiomyopathy [icdlist.com]

Functional Pattern LVEF * Mechanisms of Heart Failure Causes Indirect Myocardial Dysfunction (Not Cardiomyopathy) Dilated 42. [slideshare.net]

Dilated Cardiomyopathy Type 3B

Cardiac manifestations include pericarditis, supraventricular tachycardias, and heart block. [60] Myocardial involvement/systolic dysfunction has also been described, although [emedicine.medscape.com]

Pitt B, Remme W, Zannad F: Eplerenone, a Selective Aldosterone Blocker, in Patients with Left Ventricular Dysfunction after Myocardial Infarction. [ojrd.biomedcentral.com]

Libman-Sacks Disease

dysfunction See also systemic lupus erythematosus Promoted articles (advertising) [radiopaedia.org]

Myocardial catastrophe. A case of sudden, severe myocardial dysfunction. CIrculation 2014; 130:854-62. (15) Scoble T, Wijetilleka S, Khamashta M.A. [revistas.unc.edu.ar]

dysfunction Treatment Treatment is difficult - correction of the underlying cause is of paramount importance In patients with potentially curable cancer, coagulopathy should [pathologyoutlines.com]

Left Ventricular Noncompaction

The severity of LVNC by imaging criteria was not associated with positive genetic testing, co-occurring cardiac features, pathogenesis, family history, or myocardial dysfunction [ncbi.nlm.nih.gov]

[…] might be associated with this distinct cardiomyopathy and whether this might contribute to myocardial dysfunction. (16) Quantitative evaluation of regional myocardial perfusion [web.archive.org]

Conversely, the cohort of patients with a diagnosis of LVNC and no signs of functional cardiomyopathy (no myocardial dysfunction, cardiac dilation, or arrhythmias) are distinctive [dx.doi.org]

Hemochromatosis-Related Cardiomyopathy

Tissue Doppler echocardiography in patients with thalassaemia detects early myocardial dysfunction related to myocardial iron overload. [wikiecho.org]

Myocardial iron was normal in patients with other causes of LV dysfunction. [jcmr-online.biomedcentral.com]

Abnormal Origin of the Pulmonary Artery

Rüssel IK, Götte MJ, Bronzwaer JG, Knaapen P, Paulus WJ, van Rossum AC: Left ventricular torsion: an expanding role in the analysis of myocardial dysfunction. [karger.com]

dysfunction. [omicsonline.org]

LV scarring and diminished LV function Leads to: Myocardial ischemia Left ventricular dysfunction Mitral insufficiency Congestive heart failure Arrhythmias Sudden Death It [pedemmorsels.com]