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27 Possible Causes for Myocardial Iron Deposition

  • Hemochromatosis

    iron deposition.[jsum.or.jp] Right ventricular endomyocardial biopsy revealed multiple myocardial hemosiderin deposits, and he was diagnosed with cardiac hemochromatosis.[ncbi.nlm.nih.gov] Heart: enlarged with hemosiderin within myocardial fibers Joints: acute synovitis, calcium pyrophosphate deposition (pseudogout) Pancreas: intensely pigmented, diffuse interstitial[pathologyoutlines.com]

  • Carotid Sinus Syncope

    Hemochromatosis 548 Systemic iron deposition causing liver disease, skin pigmentation, diabetes mellitus, arthropathy, impotence, and dilated cardiomyopathy.[ahajournals.org] AV block is the likely cause, although VA may occur with myocardial involvement.[ahajournals.org] Myocardial involvement more common than sick sinus syndrome and AV conduction disease.[ahajournals.org]

  • Hereditary Spherocytosis

    Right ventricular endomyocardial biopsy revealed multiple myocardial hemosiderin deposits, and he was diagnosed with cardiac hemochromatosis.[ncbi.nlm.nih.gov] In addition to the iron deposition in the heart, the loss of myocyte and severe interstitial fibrosis were present.[ncbi.nlm.nih.gov]

  • Ventricular Arrhythmia

    BACKGROUND: Recent canines studies have shown that iron deposition within chronic myocardial infarction (CMI) influences the electric behavior of the heart.[ncbi.nlm.nih.gov] To date, the link between the iron deposition and malignant ventricular arrhythmias in humans with CMI is unknown.[ncbi.nlm.nih.gov]

  • Cooley's Anemia

    iron deposition can be quantified reproducibly with myocardial T2.[de.slideshare.net] Based on the first T2* MRI, the patients’ myocardial iron depositions were classified into three groups: T2* MRI 20 ms (low-risk group).[springermedizin.de] Iron overload causes iron deposition in tissues causing severe complications including liver cirrhosis, liver carcinoma, myocardial siderosis, testicular failure and failure[symptoma.com]

  • Primary Cardiomyopathy

    Non-invasive diagnosis of cardiac involvement is dependent on demonstration of myocardial iron deposit on cardiac MRI [ 75 ].[intechopen.com] In cases with established cardiac involvement, assessment of myocardial kinetics by Doppler and tissue strain may reveal functional impairment prior to development of overt[intechopen.com]

  • Thalassemia

    Myocardial iron deposition seems to be the trigger for the development of heart failure in thalassemia major.[circheartfailure.ahajournals.org] iron deposition in some patients with thalassemia major may not directly affect left ventricular contractility, but it may rather cause left ventricular myocardial restriction[circheartfailure.ahajournals.org] […] in 7 elderly patients (12%) with highly elevated serum ferritin levels. 21 These findings were confirmed later by separate investigators. 22 It has been postulated that myocardial[circheartfailure.ahajournals.org]

  • Neonatal Hemochromatosis
  • Hemochromatosis-related Cardiomyopathy

    These patients probably have myocardial iron deposition.[omicsonline.org] Apart from myocardial iron deposition, there have been 3 alternative proposed explanations.[jcmr-online.biomedcentral.com] BACKGROUND: Myocardial reflectivity is abnormally increased in patients with thalassemia major under transfusion treatment, probably due to myocardial iron deposits and/or[rwjms1.umdnj.edu]

  • Beta Thalassemia

    Myocardial iron deposition seems to be the trigger for the development of heart failure in thalassemia major.[circheartfailure.ahajournals.org] deposition; in individuals with TM who have low body iron, the GSTM1-null genotype is a predisposing factor for myocardial iron overload, possibly due to enhanced entry of[nature.com] iron deposition in some patients with thalassemia major may not directly affect left ventricular contractility, but it may rather cause left ventricular myocardial restriction[circheartfailure.ahajournals.org]

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