Myokymia: Causes & Reasons

Possible Causes for Myokymia

In addition, myokymia (rippling of muscles, diagnosable by electromyography) is evident during and between attacks. [ncbi.nlm.nih.gov]

All of the affected family members had episodes typically lasting for several hours, and none of them had muscle abnormalities including myokymia. [ncbi.nlm.nih.gov]

One type of EA is characterized by brief episodes of ataxia with myokymia (rippling of muscles) evident between attacks. [ncbi.nlm.nih.gov]

Facial Spasm

One type is superior oblique myokymia. [en.wikipedia.org]

[Nom commun] Myokymia, Hemifacial [Nom commun] Myokymie hémifaciale [Nom commun] Hémispasme facial [Nom commun] Spasme facial unilatéral [Nom commun] Informations Note publique [idref.fr]

Facial myokymia - Myokymia is the spontaneous, fine fascicular contractions of muscle without muscular atrophy or weakness. [blepharospasm.org]

Myotonic Syndrome

Neuromyotonia and myokymia Robert Layzer MD (Dr. Layzer of the University of California, San Francisco, has no relevant financial relationships to disclose.) [medlink.com]

Facial myokymia in multiple sclerosis. Brain. 1961. 84:31-44. Blunt SB, Khalil NM, Perkin GD. Facial myokymia in multiple system atrophy. [emedicine.medscape.com]

Fibrillations and myokymia may also occur. Neuromyotonia NMT a.k.a. [learningneurology.com]

Paramyoclonus Multiplex

Facial myokymia in multiple sclerosis. Brain. 1961. 84:31-44. Blunt SB, Khalil NM, Perkin GD. Facial myokymia in multiple system atrophy. [emedicine.medscape.com]

Most patients with facial or focal limb myokymia are not particularly disturbed by the myokymia itself. [emedicine.medscape.com]

Drug-induced myoclonus Palatal myoclonus Use Additional Code code for adverse effect, if applicable, to identify drug ( T36 - T50 with fifth or sixth character 5) Excludes1 facial myokymia [icd10coded.com]

Drug-Induced Myopathy

A 26-year-old man, who had started treatment for pulmonary tuberculosis, developed polyarthralgia, generalised myalgia, weakness, and elevated uric acid and creatine kinase levels. His polyarthralgia improved on cessation of pyrazinamide, but the improvement in his myalgia and creatine kinase was delayed. Drug-induced[…] [ncbi.nlm.nih.gov]

Autosomal Recessive Spinocerebellar Ataxia 18

1 MYOKYMIA 1 WITH HYPOMAGNESEMIA Kv1.5 (K7/45) ATRIAL FIBRILLATION, FAMILIAL, TYPE 7 Laforin (N84/1) PROGRESSIVE MYOCLONIC EPILEPSY, TYPE 2A MMACHC (N230/21) METHYLMALONIC [neuromab.ucdavis.edu]

EPISODIC ATAXIA, TYPE 1; EA1 PAROXYSMAL ATAXIA WITH NEUROMYOTONIA, HEREDITARY EPISODIC ATAXIA WITH MYOKYMIA; EAM ATAXIA, EPISODIC, WITH MYOKYMIA; AEM; AEMK MYOKYMIA WITH PERIODIC [slideshare.net]

[…] homolog of potassium channel, voltage-gated, shaker-related subfamily, member 1 potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia [ukgtn.nhs.uk]

Autosomal Dominant Spastic Ataxia Type 1

EA Episodic ataxia with myokymia Eam ataxia, episodic, with myokymia AEM Aemk paroxysmal ataxia with neuromyotonia, hereditary myokymia with periodic ataxia Episodic ataxia [diseaseinfosearch.org]

Autosomal Recessive Spinocerebellar Ataxia 8

1 MYOKYMIA 1 WITH HYPOMAGNESEMIA Kv1.5 (K7/45) ATRIAL FIBRILLATION, FAMILIAL, TYPE 7 Laforin (N84/1) PROGRESSIVE MYOCLONIC EPILEPSY, TYPE 2A MMACHC (N230/21) METHYLMALONIC [neuromab.ucdavis.edu]

EA1 may begin in early childhood with attacks of ataxia lasting minutes and with interictal myokymia. [tchain.com]

Autosomal Recessive Spinocerebellar Ataxia Type 17

myokymia; thus, the denomination of FDFM was misleading. [movementdisorders.org]

Familial Dyskinesia and Facial Myokymia

MalaCards based summary : Dyskinesia, Familial, with Facial Myokymia, also known as fdfm, is related to isolated facial myokymia and myokymia with neonatal epilepsy, and has [malacards.org]

用myokymia造句, 用myokymia造句, 用myokymia造句, myokymia meaning, definition, pronunciation, synonyms and example sentences are provided by ichacha.net. [eng.ichacha.net]

Symptoms of Dyskinesia, familial, with facial myokymia Clinical features : Imported from Human Phenotype Ontology (HPO) Abnormality of head or neck Facial myokymia Abnormality [familydiagnosis.com]

Blepharospasm

If your eyelid is twitching a lot, you might have blepharospasm, hemifacial spasm. or eyelid myokymia. [my.clevelandclinic.org]

[…] of the lid or eye (e.g. blepharitis, dry eyes, corneal foreign body) Differential diagnosis: hemifascial spasms — idiopathic or a brainstem lesion; may need an MRI eyelid myokymia [litfl.com]

Blepharospasm may be differentiated from conditions like: Ocular myokymia: Ocular myokymia is characterised by spontaneous, fine fascicular contractions of orbicularis oculi [aimu.us]

Spinocerebellar Ataxia Type 5

[…] mutation (transition C>T at nucleotide position 1438), the proband having a much more severe phenotype with global developmental delay, hypotonia, tremor, nystagmus, and facial myokymia [ncbi.nlm.nih.gov]

Facial myokymia is a prominent feature among the French kindred. Nystagmus is less prominent than in SCA6 or SCA8. [ataxia.uchicago.edu]

Hemifacial Spasm

RESULTS: Facial myokymia was associated with a clinical or radiologic relapse in 11 of 28 patients. [ncbi.nlm.nih.gov]

[Nom commun] Myokymia, Hemifacial [Nom commun] Myokymie hémifaciale [Nom commun] Hémispasme facial [Nom commun] Spasme facial unilatéral [Nom commun] Informations Note publique [idref.fr]

It is important to distinguish this from other causes of facial spasms, such as psychogenic facial spasm, facial tic, facial myokymia, blepharospasm, and tardive dyskinesia [ncbi.nlm.nih.gov]

X-Linked Spinocerebellar Ataxia Type 5

Acetazolamide-Responsive Myotonia

[…] syndrome - (AD) 7.12 Potassium voltage-gated channel, shaker-related subfamily, member 1 * Episodic ataxia with myokymia - EA1 Thyrotoxic hypokalemic periodic paralysis 7.13 [musclegenetable.fr]

August 2008 The episodic ataxias are a group of autosomal-dominant diseases characterized by episodic attacks of ataxia with or without interictal neurologic symptoms (e.g., myokymia [humpath.com]

& Benign Neonatal Epilepsy (BFNS1) 13 ● KCNQ2 ; Chromosome 20q13.33; Dominant Global Developmental delay, Myokymia & Peripheral Nerve Hyperexcitability 62 ● Leucine-rich [neuromuscular.wustl.edu]

Infantile-Onset Autosomal Recessive Non-Progressive Cerebellar Ataxia

Myokymia, vertigo, or hearing loss may occur in some of the subtypes. [blueprintgenetics.com]

Purkinje cells, dorsal root sensory ganglion neurons, and ascending posterior columns Spinocerebellar ataxia 5 See the list below: Clinical features Cerebellar ataxia, facial myokymia [emedicine.medscape.com]

Lumbosacral Plexus Disorder

Latin: Myokymia facialis G51.8 Other disorders of facial nerve Latin: Disordines nervi facialis alii G51.9 Disorder of facial nerve, unspecified Latin: Disordo nervi facialis [mkb-dijagnoza.blogspot.com]

Radiation-induced lumbosacral plexopathy is typically less painful than infiltrative plexopathy and may be associated with myokymia on EMG. [neupsykey.com]

6 Facial nerve disorders( G51 ) 7 Bell's palsy( G51.0 ) 8 Geniculate ganglionitis( G51.1 ) 9 Melkersson's syndrome( G51.2 ) 10 Clonic hemifacial spasm( G51.3 ) 11 Facial myokymia [coder.aapc.com]

Spinocerebellar Ataxia with Axonal Neuropathy

[…] syndrome KCNC1 Epilepsy, progressive myoclonic KCNQ2 Benign familial neonatal seizures, Epileptic encephalopathy, early infantile, Myokymia KCNQ3 Seizures, benign neonatal [genda.com.ar]

Myotonia permanens

Myokymia is seen electrically. This motor activity persists during sleep. Serum CK levels may be increased. [neuroweb.us]

[…] characterized by intermittent or continuous widespread involuntary muscle contractions; fasciculation; hyporeflexia; muscle cramp; muscle weakness; hyperhidrosis; tachycardia; and myokymia [icd10data.com]

Syringobulbia

A patient with a 2-year history of progressive ataxia and tingling in the right hand had prominent facial myokymia. [ncbi.nlm.nih.gov]

Facial myokymia in syringobulbia. Arch Neurol. 1990; 47 (4):472-4. 10. Carroll AM, Brackenridge P. [beat-journal.com]

[…] appraisal. ( 1479391 ) Morgan D....Williams B. 1992 35 Risk of sudden death during sleep in syringomyelia and syringobulbia. ( 1640236 ) NoguAcs M.A....Encabo H. 1992 36 Facial myokymia [malacards.org]

Cerebellar Ataxia with Peripheral Neuropathy Type 2

There is no interictal myokymia but gaze-evoked nystagmus is seen. [jpgmonline.com]

Horizontal Gaze Palsy with Progressive Scoliosis

Associated with pendular nystagmus, progressive scoliosis, and facial contraction with myokymia. Neurology 1975;25:1035-1040. 10. [repository.countway.harvard.edu]

Associated with pendular nystagmus, progressive scoliosis, and facial contraction with myokymia. Neurology 25, 1035-40. (1975). Granat, M., Friedman, Z. & Aloni, T. [childrenshospital.org]

Familial paralysis of horizontal gaze: associated with pendular nystagmus, progressive scoliosis, and facial contraction with myokymia. [ajnr.org]

Neuromuscular Junction Disorder

Manifestations include muscle weakness; fasciculation; muscle atrophy; spasm; myokymia; muscle hypertonia, myalgias, and muscle hypotonia. [icd10data.com]

[…] presynaptic membrane  Inhibition of VGKC prolongs depolarization, thereby increasing AcH release  Increased AcH hyperexcites postsynaptic membrane, resulting in twitching or myokymia [slideshare.net]

[…] association with thymoma, MG, and CNS symptoms, such as limbic encephalitis, personality changes, hallucinations, and sleep disturbances.74 Patients with neuromyoto-nia have myokymia [what-when-how.com]

Ataxia-Telangiectasia-Like Disorder Type 1

There is no interictal myokymia but gaze-evoked nystagmus is seen. [jpgmonline.com]

Autosomal Recessive Spinocerebellar Ataxia

Myokymia, vertigo, or hearing loss may occur in some of the subtypes. [blueprintgenetics.com]

Myokymia with Neonatal Epilepsy

It was analysed, why this particular mutation caused not only benign familial neonatal convulsions in the patients but myokymia as well. [oops.uni-oldenburg.de]

Their enrichment at the axonal surface is impaired by mutations in KCNQ2 carboxy-terminal tail that cause benign familial neonatal convulsion (BFNC) and myokymia, suggesting [aesnet.org]

Myokymia and neonatal epilepsy caused by a mutation in the voltage sensor of the KCNQ2 K+ channel. [modeldb.science]

Ataxia with Fasciculations

Rev-Neurol. 2000 Dec 16-31; 31(12): 1225-8 Gutmann,-L; Libell,-D; Gutmann,-L When is myokymia neuromyotonia? [malattierare.regione.veneto.it]

Ocular Neuromyotonia

Myokymia and neuromyotonia are almost always found together in peripheral nerve disorders, yet in the extraocular muscles we encounter two rather distinct syndromes: myokymia [journals.lww.com]

Superior oblique myokymia. Ann Neurol. 1983 Jun;13(6):667–669. [PubMed] [Google Scholar] Lee JP. Superior oblique myokymia. A possible etiologic factor. [ncbi.nlm.nih.gov]

Two cases had previous cranial radiation, two had thyroid eye disease and one had superior oblique myokymia that progressed to ONM. [eyenews.uk.com]

Hereditary Continuous Muscle Fiber Activity

Rev-Neurol. 2000 Dec 16-31; 31(12): 1225-8 Gutmann,-L; Libell,-D; Gutmann,-L When is myokymia neuromyotonia? [malattierare.regione.veneto.it]

Asymmetric Motor Neuropathy

Motor neuropathy with proximal multifocal persistent conduction block, fasciculations and myokymia. Evolution to tetraplegia. Eur Neurol 1986;25(6):416–423. [springermedizin.de]