Myopathy: Causes & Reasons

Possible Causes for Myopathy

Nemaline myopathy Nemaline myopathy. Clusters of rod bodies. Gomori trichrome. Nemaline myopathy Nemaline myopathy. EM. [neuropathology-web.org]

In this study we describe a boy with HMGCR-positive necrotizing myopathy and highlight the clinical features of the patient. [ncbi.nlm.nih.gov]

Differential diagnosis Differential diagnoses include milder congenital myopathies (central core disease and centronuclear myopathy) and distal myopathies (Udd distal myopathy [orpha.net]

Duchenne Muscular Dystrophy

Exemple avec la myopathie de Duchenne dont Simon est atteint depuis l'âge de 2 ans. [youtube.com]

Because of the infiltration of degenerating muscles with… Read More myopathy In myopathy …most common muscular dystrophy is Duchenne’s, an X-chromosome-linked disorder involving [britannica.com]

Some muscle disorders, such as the mitochondrial and lipid storage myopathies, result from a genetic defect in an enzyme necessary in metabolism. [britannica.com]

Rhabdomyolysis

How common is statin induced myopathy? [doi.org]

[…] myositis Sarcocystis myositis Immune-mediated myopathy Nutritional myopathy Vitamin E and selenium deficiency Toxic myopathy Ionophore toxicity Pasture myopathies Rayless [web.archive.org]

[…] for patients with mitochondrial myopathies. 5 Conclusion Mitochondrial myopathies should be considered in patients presenting with recurrent muscle pain and elevation of [jaoa.org]

Acute Exertional Rhabdomyolysis

These include metabolic myopathies, disorders of calcium homoeostasis and other structural myopathies, and the sickle cell trait ( table 1 ). [bmjopensem.bmj.com]

Minicore (multicore) myopathy Minicore (multicore) myopathy Minicore myopathy, also called, multicore myopathy and multiminicore myopathy, falls under the umbrella of congenital [docplayer.net]

Apoptosis and apoptosis-related proteins in thyroid myopathies. Muscle Nerve 26: 383, 2002. [link.springer.com]

Paroxysmal Rhabdomyolysis

Type 2 muscle atrophy - Alcoholic myopathy, Thomas Klopstock, M.D.,1994, last updated 2011 PATHOGENESIS Acute Alcoholic Myopathy Acute alcoholic myopathy develops suddenly [flipper.diff.org]

Recessive mutations in ANO5 (OMIM#608662) cause a wide spectrum of myopathies including LGMD2L, distal myopathy and isolated hyperCKemia. [ojrd.biomedcentral.com]

[…] addresses the complete range of specific neuromuscular diseases: neuronopathies, peripheral neuropathies, neuromuscular junction disorders, muscle ion channel disorders, myopathies [books.google.com]

Secondary Myopathy

Acquired myopathies can be subclassified as inflammatory myopathies, toxic myopathies, and myopathies associated with systemic conditions. [clevelandclinicmeded.com]

[…] of myopathies has dramatically increased. [link.springer.com]

[…] and diagnose myopathy. [patient.info]

Traumatic Rhabdomyolysis

) muscular dystrophies and myopathies ( G71 - G72 ) myopathy in amyloidosis ( E85.- ) myopathy in polyarteritis nodosa ( M30.0 ) myopathy in rheumatoid arthritis ( M05.32 [icd10data.com]

It can be induced by numerous factors, including a crush injury to a limb, overuse of skeletal muscle, heat, alcoholism, viral infections, metabolic disorders, myopathies, [nejm.org]

myopathy in scleroderma ( M34.- ) myopathy in Sjögren's syndrome ( M35.03 ) myopathy in systemic lupus erythematosus ( M32.- ) Disorders of muscles M62 ICD-10-CM Diagnosis [icd10data.com]

Becker Muscular Dystrophy

In a boy with myopathy and an increase of muscle fibres with central nuclei we detected a heterozygous 387G-->T nucleotide transversion in the MYF6 gene (MIM*159991). [ncbi.nlm.nih.gov]

We describe two families which were initially classified as metabolic myopathies, until the diagnosis of atypical BMD was established after dystrophin analysis at the protein [ncbi.nlm.nih.gov]

X-linked recessive inherited disorder characterized by slowly progressive muscle weakness of the legs and pelvis Benign pseudohypertrophic muscular dystrophy benign congenital myopathy [wikidata.org]

Late-Onset Pompe Disease

(5), active myopathy (4), chronic and active myopathy (2), and myopathy with denervation features (3) (Table). [scielo.br]

myofibrillar myopathies, metabolic myopathies and others [42]. [ncbi.nlm.nih.gov]

Although myotonic discharges are nonspecific and can be seen in many disorders, including myotonic dystrophy, inflammatory myopathies, and some inherited myopathies, the presence [ncbi.nlm.nih.gov]

MELAS Syndrome

Familial poliodystrophy, mitochondrial myopathy, and lactate acidemia. [scielo.br]

Google Scholar Sakuta R., Nonaka I. : Vascular involvement in mitochondrial myopathy. Ann Neurol 1989 ;25: 594 - 601. [doi.org]

Mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes (MELAS): current concepts. [scielo.br]

Polymyositis

Furthermore, glucocorticosteroid (GC) toxicity leads to a significant disability known as steroid myopathy, particularly in elderly patients. [ncbi.nlm.nih.gov]

In some patients, however, manifestations of CTD overlap with inflammatory myopathy. [neuropathology-web.org]

myopathies. [ncbi.nlm.nih.gov]

Limb-Girdle Muscular Dystrophy

For this reason our finding extends the histological spectrum of myopathies due to ANO5 mutations as well as the possible differential diagnoses for necrotizing myopathy. [ncbi.nlm.nih.gov]

In this report, a French family with an autosomal-dominant late-onset distal myopathy of the tibial muscular dystrophy phenotype segregating in several members of the family [ncbi.nlm.nih.gov]

Arahata K, Engel AG (1984) Monoclonal antibody analysis of mononuclear cells in myopathies. I. [link.springer.com]

Oculopharyngeal Muscular Dystrophy

[…] some ultrastructural characteristics with distal myopathy with rimmed vacuoles and hereditary inclusion body myopathy. [ncbi.nlm.nih.gov]

Inclusion body myopathy with joint contractures & ophthalmoplegia Missense mutation in PABPN1 Oculopharyngodistal myopathy ● Autosomal Dominant or Recessive Epidemiology [neuromuscular.wustl.edu]

Ultrastructural studies in groups of autosomal recessive oculopharyngodistal myopathy and distal myopathy with rimmed vacuoles disclosed a collection of cytoplasmic filaments [ncbi.nlm.nih.gov]

Erb Muscular Dystrophy

Observations on myopathy. Proc R Soc Med. 1922. 16:1. [emedicine.medscape.com]

ocular Mitochondrial ocular myopathy Muscular dystrophy Muscular dystrophy, distal Muscular dystrophy, Duchenne Muscular dystrophy, Emery Dreifuss Muscular dystrophy, Erbs [icd9data.com]

Families have been reported in which some members develop LGMD2B and others Miyoshi myopathy. [rarediseases.org]

Facioscapulohumeral Muscular Dystrophy

OBJECTIVES: To report cases of chronic autoimmune necrotizing myopathy with anti-signal recognition particle antibodies (anti-SRP myopathy) initially misdiagnosed as muscular [ncbi.nlm.nih.gov]

Most genetically confirmed FSHD patients exhibit unspecific morphological signs of a degenerative myopathy. [ncbi.nlm.nih.gov]

It is the 3rd most common form of hereditary myopathy. Clinical description Onset occurs between 3 and 60 years of age. [orpha.net]

Tropical Myositis

HTLV-1 associated inflammatory myopathies (HAIM) present similarities with idiopathic inflammatory myopathies (IIM) and with tropical spastic paraparesis or HTLV-1 associated [theses.fr]

) muscular dystrophies and myopathies ( G71 - G72 ) myopathy in amyloidosis ( E85.- ) myopathy in polyarteritis nodosa ( M30.0 ) myopathy in rheumatoid arthritis ( M05.32 [icd10data.com]

) muscular dystrophies and myopathies ( G71-G72 ) myopathy in: · amyloidosis ( E85.- ) · polyarteritis nodosa ( M30.0 ) · rheumatoid arthritis ( M05.3 ) · scleroderma [apps.who.int]

Dermatomyositis

Necrotising myopathy, an unusual presentation of a steroid-responsive myopathy. [doi.org]

Idiopathic inflammatory myopathies are commonly a part of overlap myopathy (OM) and/or antisynthetase syndrome. [doi.org]

Classification of the Autoimmune Myopathies. View Table | Favorite Table | Download (.pdf) Table 27–1. Classification of the Autoimmune Myopathies. [accessmedicine.mhmedical.com]

Non-Dystrophic Myotonia

Mitochondrial Myopathies. [practicalneurology.com]

With IMNM, the EMG may show an irritable myopathy pattern as with other inflammatory myopathies. [understandingmyositis.org]

They suggested that this may represent a new disorder and referred to the condition as proximal myotonic myopathy (PROMM). [jnnp.bmj.com]

Chronic Progressive External Ophthalmoplegia

Here, we report a patient with chronic progressive external ophthalmoplegia complicated with inflammatory myopathy and after treated with prednisone as myositis, he had a [ncbi.nlm.nih.gov]

In conclusion, mitochondrial myopathy was definitely diagnosed. [ncbi.nlm.nih.gov]

How is mitochondrial myopathy diagnosed? [mda.org.au]

Pompe Disease

Glycogen storage disease type III: modified Atkins diet improves myopathy. [ojrd.biomedcentral.com]

The myopathy may also cause respiratory distress, and Pompe disease often presents as exercise intolerance. [youtube.com]

＋) 부갑상선기능저하증에서의 근병증(Myopathy in hypoparathyroidism)(E20.-＋) 갑상선중독증성 근병증(Thyrotoxic myopathy)(E05.-＋) G73.6*대사성 질환에서의 근병증(Myopathy in metabolic diseases) 당원축적 질환에서의 근병증(Myopathy [dic.impact.pe.kr]

McArdle Disease

Haller, Metabolic and Mitochondrial Myopathies, Neurologic Clinics, 32, 3, (777), (2014). [doi.org]

Turnbull, Investigation of metabolic myopathies, Myopathies, 10.1016/S0072-9752(07)86009-X, (193-204), (2007). G. Nogales-Gadea, J. Arenas and A. L. [doi.org]

Michael Benatar, Metabolic Myopathy, Neuromuscular Disease, 10.1007/978-1-59745-106-2_22, (397-419), (2006). [doi.org]

Glycogen Storage Disease Type 7

McArdle: Myopathy due to a defect in muscle glycogen breakdown. Clinical Science, London, 1951, 10: 13-33. S. Tarui, G. Okuno, Y. [whonamedit.com]

Turnbull, Investigation of metabolic myopathies, Myopathies, 10.1016/S0072-9752(07)86009-X, (193-204), (2007). Zuhair N. [doi.org]

In the late-onset form of GSDVII, myopathy is typically the only feature. [ghr.nlm.nih.gov]

Schwartz-Jampel Syndrome

Structural and functional mutations of the perlecan gene cause Schwartz-Jampel syndrome, with myotonic myopathy and chondrodysplasia. [jhu.pure.elsevier.com]

[…] autosomal recessive disease characterized by neuromyotonia and chondrodysplasia that has material basis in hypomorphic mutations in the HSPG2 gene on chromosome 1p36 myotonic myopathy [wikidata.org]

E-mail: [email protected] Abstract: Schwartz-Jampel syndrome, also known as chondrodystrophica myotonia or myotonic myopathy is a rare, autosomal recessive disorder resulting [content.iospress.com]

Paramyotonia Congenita

[…] a myopathy. [web.archive.org]

myopathy. [mayoclinic.org]

Paramyotonia congenita is an inherited myopathy, a disease that causes problems with the tone and contraction of skeletal muscles. [mda.org]

Myotonia Congenita

myopathy. [mayoclinic.org]

myopathy, fiber-type disproportion myopathy, and myosin storage myopathy [1]. 2.1. [intechopen.com]

Mitochondrial Myopathies. [practicalneurology.com]

Myotonic Dystrophy

Nemaline myopathy Nemaline myopathy. Clusters of rod bodies. Gomori trichrome. Nemaline myopathy Nemaline myopathy. EM. [neuropathology-web.org]

[…] management of patients with myopathies is challenging. [deepdyve.com]

G71.3 Mitochondrial myopathy, not elsewhere classified G71.8 Other primary disorders of muscles G71.9 Primary disorder of muscle, unspecified G72 Other and unspecified myopathies [icd10data.com]

Inclusion Body Myositis

Therefore, these are better termed as ‘myopathies’ [ 5 ]. [ageing.oxfordjournals.org]

The comorbidity of inclusion body myositis and sarcoid myopathy is rare. [ncbi.nlm.nih.gov]

Sporadic inclusion body myositis (sIBM) is an insidious late-onset progressive myopathy that typically affects patients over the age of 50. [ncbi.nlm.nih.gov]

Childhood Dermatomyositis

Juvenile dermatomyositis, the most common inflammatory myopathy of childhood, is a rare systemic autoimmune vasculopathy that is characterised by weakness in proximal muscles [ncbi.nlm.nih.gov]

Juvenile dermatomyositis with respiratory involvement Juvenile dermatopolymyositis Juvenile dermatopolymyositis w lung involvement Juvenile dermatopolymyositis w myopathy [icd9data.com]

Inflammatory myopathies: Polymyositis, dermatomyositis, and related conditions. [link.springer.com]

Carnitine Transporter Deficiency

There is lipid myopathy with microvesicular lipid accumulation found in the muscle and liver as well as elevated liver transaminases and hyperammonemia. [orpha.net]

Analysis of lipid profile in lipid storage myopathy Aguennouz M, Beccaria M, Purcaro G, et al. Journal of chromatography. [myobase.org]

[…] consumed (resulting in hypoglycemia) and the fat released from adipose tissue accumulates in the liver, heart and skeletal muscle (leading to hepatic steatosis and lipid myopathy [orpha.net]

Neuromuscular Junction Disorder

In rare myopathies (with involvement of the levator muscle of upper eyelid), ptosis is usually an isolated ocular sign, and bilateral in congenital myopathies, glycogen storage [atlasofscience.org]

Hyperthyroid myopathy Myotonia congenita Myotubular myopathy Nemaline myopathy Paramyotonia congenita Periodic paralysis-hypokalemic-hyperkalemic [hopkinsmedicine.org]

Conditions and symptoms Amyotrophic lateral sclerosis (ALS) Botulism Congenital myasthenic syndromes Congenital myopathies Cramp-fasciculation syndrome Elevated creatine kinase [mayoclinic.org]