Nail Abnormality: Causes & Reasons

Possible Causes for Nail Abnormality

Ingrowing of the nail of the hallux has been ascribed to an abnormality of the shape of the nail; our prospective study was planned to test this association. [ncbi.nlm.nih.gov]

Simple cure for the ingrown toenailAust Fam Physician1998274299 ↵ PearsonHJBuryRNWapplesJWatkinDFIngrowing toenails: is there a nail abnormality? [cfp.ca]

Our results suggest that the ingrowth is not commonly associated with an abnormal shape of the nail. [ncbi.nlm.nih.gov]

Dyskeratosis Congenita

The most common nail abnormalities are longitudinal ridges, pterygium, or atrophic / absent nails. [visualdx.com]

The classic triad of dysplastic nails, abnormal skin pigmentation, and oral leukoplakia is diagnostic of DC, but substantial clinical heterogeneity exists; the clinically [ncbi.nlm.nih.gov]

It is characterized by reticulated hyperpigmentation of the neck, face, and trunk, palmar hyperkeratosis, premalignant leukoplakia, and nail abnormalities. [visualdx.com]

Hidrotic Ectodermal Dysplasia

Showing of 43 | 80%-99% of people have these symptoms Abnormality of nail color Abnormality of nail colour 0100643 Alopecia Hair loss 0001596 Fragile nails Brittle nails 0001808 [rarediseases.info.nih.gov]

The presence of nail abnormalities with hypotrichosis also separates our case from various forms of atrichia congenita or congenital hypotrichosis. [ijpd.in]

Symptoms to look for in individuals include abnormal nails and sparse hair. [nfed.org]

Nail-Patella Syndrome

[…] syndrome Features: Nails: 80-90% of patients have nail abnormalities, with absent or dysplastic nails. [pedsradiology.com]

Description Nail-patella syndrome is characterized by abnormalities of the nails, knees, elbows, and pelvis. [medlineplus.gov]

All patients had nail abnormalities (100%), the most frequent finding being hyponychia. Triangular lunulae were observed in four patients. [ncbi.nlm.nih.gov]

Onychomycosis

It is the most common disease of the nails and constitutes about half of all nail abnormalities. [imedpub.com]

What Does a Fungal Nail Infection Look Like? Onychomycosis presents as nail abnormality or a progressive degeneration of the nail tissue (dystrophy). [probitymedical.com]

[…] bed Onychomycosis accounts for up to 30% of all superficial infections of skin and constitutes about a half of all nail abnormalities; affecting approximately 5% of population [clinicaltrials.gov]

Pachyonychia Congenita

Pachyonychia congenita type I is an autosomal dominant disorder where nail abnormalities are a constant feature and develop during childhood. [ncbi.nlm.nih.gov]

Pachyonychia congenita (PC) is a rare genodermatosis with characteristic nail abnormalities and occasional palmoplantar keratoderma and leukokeratosis oris; alopecia may occur [ncbi.nlm.nih.gov]

The abnormal appearance of the nails can also cause social and psychological problems. [socialstyrelsen.se]

Pachyonychia Congenita Type 1

No nail abnormalities were observed even one year after stopping treatment. Two major subtypes of pachyonychia congenita are recognized. [ijdvl.com]

[…] thickening * Abnormal nails * Thick skin on palms * Thick skin on soles * Painful blistered calluses on soles of feet * Painful blistered calluses on palms of hands * Premature [checkorphan.org]

The abnormal appearance of the nails can also cause social and psychological problems. [socialstyrelsen.se]

Paronychia

Nail abnormalities were rated as cured (regrowth of cuticle with normal proximal nail fold), improved (proximal nail fold not inflamed, absence of cuticle, nail plate growing [mdedge.com]

References https://medlineplus.gov/ency/article/001444.htm http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884921/ http://www.nhs.uk/conditions/nail-abnormalities/Pages/Introduction.aspx [news-medical.net]

Nail plate abnormalities also improved in six patients. [ncbi.nlm.nih.gov]

Hereditary Koilonychia

(Medical Encyclopedia) Nail abnormalities (Medical Encyclopedia) Nail injuries (Medical Encyclopedia) Paronychia (Medical Encyclopedia) Splinter hemorrhages (Medical Encyclopedia [icdlist.com]

"Nail Abnormalities: Clues to Systemic Disease." Am Family Physician 69.6 Mar. 15, 2004: 1417-1424. Medically Reviewed by a Doctor on 3/30/2017 Next Article [medicinenet.com]

An initial impression should be made of the nail unit, which may be either normal or abnormal looking (overall). Matrix or nail bed abnormalities are most common. [sites.google.com]

Congenital Onychodysplasia

By and large, either matrix or nail bed abnormalities are most common. [scinapse.io]

abnormalities has expanded to include malalignment and deformities of nails other than the nails of the index fingers. [dermaamin.com]

An initial impression should be made of the nail unit, which may be either normal or abnormal looking (overall). Matrix or nail bed abnormalities are most common. [sites.google.com]

Yellow Nail Syndrome

Nail abnormalities are problems with the color, shape, texture, or thickness of the fingernails or toenails. [nlm.nih.gov]

The patient reported that her grandmother had similar nail abnormality and lower extremity edema. Other family members and patient's grandchildren were healthy. [ncbi.nlm.nih.gov]

Nail abnormalities associated with systemic pathologies. Clin Dermatol. 2013;31(5):627-649. PMID: 24079592 www.ncbi.nlm.nih.gov/pubmed/24079592. [nlm.nih.gov]

Hypohidrotic Ectodermal Dysplasia

abnormalities and reduced sweating ability. [checkorphan.org]

Tricho-dento-osseous syndrome is characterized by abnormalities of the hair, teeth, bones, and/or nails. [rarediseases.org]

Adult Syndrome This is another rare condition characterized by abnormal teeth development, tear duct obstruction, nail abnormalities, pigmentation anomalies, plus hand and [hxbenefit.com]

Ellis-Van Creveld Syndrome

We report a family with complex septal cardiac defects, rhizomelic limb shortening, and polydactyly, without the typical lip, dental, and nail abnormalities of EvC. [ncbi.nlm.nih.gov]

Our patient had all the major characteristic features consistent with Ellis-van Creveld syndrome including post-axial polydactyly, teeth and nail abnormalities, congenital [ncbi.nlm.nih.gov]

Like Ellis-van Creveld syndrome, Weyers acrofacial dysostosis involves tooth and nail abnormalities, although affected individuals have less pronounced short stature and typically [ghr.nlm.nih.gov]

Curry-Hall Syndrome

Overview Curry-Hall syndrome (medical condition): A rare disorder characterized by facial abnormalities and extra digits, nail abnormalities and short limbs. [checkorphan.org]

In addition to tooth and nail abnormalities, people with Ellis-van Creveld syndrome have very short stature and are often born with heart defects. [medifind.com]

Autosomal dominant postaxial polydactyly, nail dystrophy, and dental abnormalities map to chromosome 4p16, in the region containing the Ellis-van Creveld syndrome locus. [medlineplus.gov]

Tricho-Dento-Osseous Syndrome

Symptoms to look for in children: Abnormal teeth Abnormal nails Abnormal hair Skeletal manifestations Causes of TDO Syndrome TDO is caused by as mutation in the DLX3 gene [nfed.org]

Tooth abnormalities are the only clinical features seen in individuals with AI4, while individuals with TDO also have hair, nail, and bone abnormalities. read more [ctgt.net]

In some cases, affected individuals also exhibit abnormally thin, brittle nails or premature closure (fusion) of the fibrous joints between certain bones in the skull (craniosynostosis [hekim.org]

Onychia

External links[edit] Fungal Nail Infections - explanation covering causes, treatment, and prevention Links to pictures of Nail Diseases (Hardin MD/Univ of Iowa) Nail Abnormalities [en.wikipedia.org]

Drug-induced nail changes are caused by drug usage which may result in various abnormalities.[6]: 665–6 Treatment[edit] In approximately half of suspected nail fungus cases [en.wikipedia.org]

Splinter hemorrhages (or haemorrhages) are tiny blood clots that tend to run vertically under the nails. [en.wikipedia.org]

Junctional Epidermolysis Bullosa

abnormalities. [ncbi.nlm.nih.gov]

[…] or teeth abnormalities. [ncbi.nlm.nih.gov]

He also presented nail dystrophy and tooth abnormalities. Mucosal involvement was limited to gingival erosion. [ncbi.nlm.nih.gov]

Pallister-Hall Syndrome

pachyonychia abnormal thickening of the nails or claws. [medical-dictionary.thefreedictionary.com]

Some features include extra fingers and/or toes (polydactyly), fusion of fingers and/or toes (syndactyly), abnormal nails, an abnormal growth in the brain called a hypothalamic [thinkgenetic.com]

[…] or toenails. pach·y·o·nych·i·a ( pak'ē-ō-nik'ē-ă ) Abnormal thickness of the fingernails or toenails. [ pachy- + G. onyx, nail] pachyonychia Abnormal thickness of the nails [medical-dictionary.thefreedictionary.com]

Incontinentia Pigmenti Achromians

Hair, tooth, and nail abnormalities can also be seen. [10] Thorough dermatologic, neurologic, and ophthalmologic examinations are extremely important given the heterogeneity [ijpd.in]

Hair, tooth, and nail abnormalities can also be seen.[10] Thorough dermatologic, neurologic, and ophthalmologic examinations are extremely important given the heterogeneity [journals.lww.com]

Papillon Lefevre Disease

abnormalities PROGNOSIS Individuals with the disorder lose their primary teeth by age 5 and lose their permanent teeth during adolescence. [evolvegene.com]

Nail abnormalities. Decreased sweating. [firstskinfoundation.org]

[…] the Disorder Sparse hair Blisters on soles of feet/palms of hand (palmoplantar keratosis) Skin infections Premature tooth loss (periodontitis) Inflammation around teeth Nail [evolvegene.com]

Ichthyosis and Male Hypogonadism

abnormalities Small testes High blood sugar Diabetes mellitus Note that Ichthyosis and male hypogonadism symptoms usually refers to various symptoms known to a patient, but [checkorphan.org]

Flexures were affected, but the palms, soles, hairs and nails were spared. An X-linked ichthyosis (XLI) was suspected. [medicaljournals.se]

[…] fibrosis Telangiectasia Narrow chest Pes valgus Short foot Full cheeks Renal hypoplasia Stage 5 chronic kidney disease Limb undergrowth Rhizomelia Functional respiratory abnormality [mendelian.co]

Plummer-Vinson Syndrome

Symptoms Difficulty swallowing Weakness Signs and tests You may develop skin and nail abnormalities thatyour doctor can see during an exam. [indiatoday.in]

Symptoms may include: Difficulty swallowing Weakness Your health care provider will do an exam to look for abnormal areas on your skin and nails. [medlineplus.gov]

Symptoms Symptoms may include: Difficulty swallowing Weakness Exams and Tests Your health care provider will do an exam to look for abnormal areas on your skin and nails. [ufhealth.org]

Raynaud Syndrome

Abnormal nail-fold capillary patterns can suggest the possibility of an associated rheumatic condition. [medicinenet.com]

Furthermore, capillary nail-fold abnormalities can frequently be found as described above. What specialties of doctors treat Raynaud's phenomenon? [medicinenet.com]

Pretibial Dystrophic Epidermolysis Bullosa

nails due to abnormal type 7 collagen in anchoring fibrils May also get blistering of the oesophagus Generalised severe recessive (R) DEB Previously known as Hallopeau-Siemens [dermnetnz.org]

Lethal acantholytic EB• Mutation in gene for desmoplakin• AR• Present at birth, Generalized• Presence of oozing erosions than frank blisters• Abnormal nails, neonatal teeth [slideshare.net]

In most cases, nail dystrophy, especially of the toenails, is also present. [kclpure.kcl.ac.uk]

Epidermolysis Bullosa

Patients with unexplained blistering, itchy skin, and nail abnormalities may have a diagnosis of EB confirmed through genetic testing. [fulgentgenetics.com]

In less severe forms of junctional EB, skin fragility is accompanied by dental enamel defects, nail abnormality and loss, and sometimes sparse hair. What are the causes? [cafamily.org.uk]

In the mildest cases, abnormal nails are the only sign of the condition. [debra.org]

Dystrophic Epidermolysis Bullosa

Abnormalities Keratosis Palmoplantaris With Arrhythmogenic Cardiomyopathy Mal De Naxos Palmoplantar Keratoderma With Arrhythmogenic Right Ventricular Cardiomyopathy And Woolly [ukgtn.nhs.uk]

abnormalities with dystrophy or loss at birth or infancy may be an isolated finding as reported in DDEB [ 26, 27 ]. [plasticsurgerykey.com]

In the mildest cases, abnormal nails are the only sign of the condition. [ghr.nlm.nih.gov]

Lamellar Ichthyosis

We present the case of a young woman with the following features: lamellar ichthyosis, dwarfism, mental retardation, nail and dental abnormalities, unusual facies, poor sexual [ncbi.nlm.nih.gov]

OBJECTIVES: (i) To ascertain whether TGM1 is important for CE formation in nail; (ii) to characterize CE abnormalities occurring in LI that may be distinguished from other [ncbi.nlm.nih.gov]

[…] hairs suggest other diagnoses nails: usually normal; may become dystrophic Associated findings: often no other findings; however, the CIE phenotype is seen in many well-defined [firstskinfoundation.org]

Limb-Mammary Syndrome

Tooth, nail and sweat gland abnormalities may also be present. [checkorphan.org]

Most affected individuals have nail dystrophy (abnormal nail plate texture) and hyperconvex nail plates. [ncbi.nlm.nih.gov]

There are more than 200 ectodermal dysplasias, and they are defined by abnormalities in two or more ectodermal derivatives, including the skin, hair, nails, and teeth. [clinicaladvisor.com]

Psoriasis

Other forms include nail psoriasis, which is identifiable by pitting in the nails or abnormal nail discoloration, and guttate psoriasis, which is similar to plaque psoriasis [phillyvoice.com]

Fawcett RS, Linford S, Stulberg DL (2004) Nail abnormalities: clues to systemic disease. Am Fam Physician 69(6):1417–1424 PubMed Google Scholar 7. [dx.doi.org]

Mal de Meleda

Other features include perioral erythema, lichenoid plaques on the knees and the elbows, and nail abnormalities. [uniprot.org]

It is associated with brachydactyly and nail abnormalities. Mental retardation may also occur. [genome.jp]