Nail Abnormality: Causes & Reasons

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Possible Causes for Nail Abnormality

Onychocryptosis

Simple cure for the ingrown toenailAust Fam Physician1998274299 ↵ PearsonHJBuryRNWapplesJWatkinDFIngrowing toenails: is there a nail abnormality? [cfp.ca]

Ingrowing toenails: is there a nail abnormality? A prospective study. J Bone Joint Surg Br 1987;69(5):840–2. [web.archive.org]

[…] to demonstrate any abnormality of the nail … suggest[ing] that treatment should not be based on the correction of a nonexistent nail deformity.” 4 The Vandenbos procedure [cfp.ca]

Dyskeratosis Congenita

The most common nail abnormalities are longitudinal ridges, pterygium, or atrophic / absent nails. [visualdx.com]

The classic triad of dysplastic nails, abnormal skin pigmentation, and oral leukoplakia is diagnostic of DC, but substantial clinical heterogeneity exists; the clinically [ncbi.nlm.nih.gov]

It is characterized by reticulated hyperpigmentation of the neck, face, and trunk, palmar hyperkeratosis, premalignant leukoplakia, and nail abnormalities. [visualdx.com]

Hidrotic Ectodermal Dysplasia

Showing of 43 | 80%-99% of people have these symptoms Abnormality of nail color Abnormality of nail colour 0100643 Alopecia Hair loss 0001596 Fragile nails Brittle nails 0001808 [rarediseases.info.nih.gov]

The presence of nail abnormalities with hypotrichosis also separates our case from various forms of atrichia congenita or congenital hypotrichosis. [ijpd.in]

Symptoms to look for in individuals include abnormal nails and sparse hair. [nfed.org]

Nail-Patella Syndrome

All patients had nail abnormalities (100%), the most frequent finding being hyponychia. Triangular lunulae were observed in four patients. [ncbi.nlm.nih.gov]

Iliac horns are considered pathognomonic, and the presence of hypoplastic or aplastic patellae in conjunction with nail abnormalities is a cardinal feature of diagnosis. [tandfonline.com]

[…] syndrome Features: Nails: 80-90% of patients have nail abnormalities, with absent or dysplastic nails. [pedsradiology.com]

Pachyonychia Congenita Type 1

No nail abnormalities were observed even one year after stopping treatment. Two major subtypes of pachyonychia congenita are recognized. [ijdvl.com]

[…] thickening * Abnormal nails * Thick skin on palms * Thick skin on soles * Painful blistered calluses on soles of feet * Painful blistered calluses on palms of hands * Premature [checkorphan.org]

The abnormal appearance of the nails can also cause social and psychological problems. [socialstyrelsen.se]

Onychomycosis

It is the most common disease of the nails and constitutes about half of all nail abnormalities. [imedpub.com]

What Does a Fungal Nail Infection Look Like? Onychomycosis presents as nail abnormality or a progressive degeneration of the nail tissue (dystrophy). [probitymedical.com]

Even in cases where treatment has been effective, the nails may have persistent abnormal appearance. [probitymedical.com]

Pachyonychia Congenita

Pachyonychia congenita type I is an autosomal dominant disorder where nail abnormalities are a constant feature and develop during childhood. [ncbi.nlm.nih.gov]

Pachyonychia congenita (PC) is a rare genodermatosis with characteristic nail abnormalities and occasional palmoplantar keratoderma and leukokeratosis oris; alopecia may occur [ncbi.nlm.nih.gov]

The abnormal appearance of the nails can also cause social and psychological problems. [socialstyrelsen.se]

Hereditary Koilonychia

(Medical Encyclopedia) Nail abnormalities (Medical Encyclopedia) Nail injuries (Medical Encyclopedia) Paronychia (Medical Encyclopedia) Splinter hemorrhages (Medical Encyclopedia [icdlist.com]

"Nail Abnormalities: Clues to Systemic Disease." Am Family Physician 69.6 Mar. 15, 2004: 1417-1424. Medically Reviewed by a Doctor on 3/30/2017 Next Article [medicinenet.com]

An initial impression should be made of the nail unit, which may be either normal or abnormal looking (overall). Matrix or nail bed abnormalities are most common. [sites.google.com]

Congenital Onychodysplasia

By and large, either matrix or nail bed abnormalities are most common. [scinapse.io]

abnormalities has expanded to include malalignment and deformities of nails other than the nails of the index fingers. [dermaamin.com]

• 9 - Trachyonychia: Trachyonychia (or '20-nail dystrophy') describes a spectrum of nail-plate surface abnormalities that give the nail plate a rough appearance. [handresearch.com]

Yellow Nail Syndrome

Nail abnormalities are problems with the color, shape, texture, or thickness of the fingernails or toenails. [nlm.nih.gov]

The patient reported that her grandmother had similar nail abnormality and lower extremity edema. Other family members and patient's grandchildren were healthy. [ncbi.nlm.nih.gov]

Nail abnormalities associated with systemic pathologies. Clin Dermatol. 2013;31(5):627-649. PMID: 24079592 www.ncbi.nlm.nih.gov/pubmed/24079592. [nlm.nih.gov]

Ellis-Van Creveld Syndrome

We report a family with complex septal cardiac defects, rhizomelic limb shortening, and polydactyly, without the typical lip, dental, and nail abnormalities of EvC. [ncbi.nlm.nih.gov]

Our patient had all the major characteristic features consistent with Ellis-van Creveld syndrome including post-axial polydactyly, teeth and nail abnormalities, congenital [ncbi.nlm.nih.gov]

Weyers acrodental dysostosis (Weyers; OMIM 193530) is an allelic dominant disorder comprising polydactyly, nail dysplasia, and orofacial abnormalities. [ncbi.nlm.nih.gov]

Paronychia

Nail abnormalities were rated as cured (regrowth of cuticle with normal proximal nail fold), improved (proximal nail fold not inflamed, absence of cuticle, nail plate growing [mdedge.com]

References https://medlineplus.gov/ency/article/001444.htm http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3884921/ http://www.nhs.uk/conditions/nail-abnormalities/Pages/Introduction.aspx [news-medical.net]

Nail plate abnormalities also improved in six patients. [ncbi.nlm.nih.gov]

Hypohidrotic Ectodermal Dysplasia

abnormalities and reduced sweating ability. [checkorphan.org]

Tricho-dento-osseous syndrome is characterized by abnormalities of the hair, teeth, bones, and/or nails. [rarediseases.org]

Adult Syndrome This is another rare condition characterized by abnormal teeth development, tear duct obstruction, nail abnormalities, pigmentation anomalies, plus hand and [hxbenefit.com]

Tricho-Dento-Osseous Syndrome

Symptoms to look for in children: Abnormal teeth Abnormal nails Abnormal hair Skeletal manifestations Causes of TDO Syndrome TDO is caused by as mutation in the DLX3 gene [nfed.org]

In addition, nail abnormalities may be more striking that those associated with TDO-I, with the nails tending to be extremely thin and brittle, with upper layers that may [rarediseases.org]

Tooth abnormalities are the only clinical features seen in individuals with AI4, while individuals with TDO also have hair, nail, and bone abnormalities. read more [ctgt.net]

Curry-Hall Syndrome

Overview Curry-Hall syndrome (medical condition): A rare disorder characterized by facial abnormalities and extra digits, nail abnormalities and short limbs. [checkorphan.org]

Small nail MedGen UID: 537942 • Concept ID: C0263523 • Finding Nail dysplasia MedGen UID: 331737 • Concept ID: C1834405 • Congenital Abnormality The presence of developmental [ncbi.nlm.nih.gov]

Weyers acrofacial dysostosis is a disorder that affects the development of the teeth, nails, and bones. [medifind.com]

Onychia

Drug-induced nail changes are caused by drug usage which may result in various abnormalities.[6]:665–6 Treatment[edit] In approximately half of suspected nail fungus cases [en.wikipedia.org]

External links [ edit ] Fungal Nail Infections - explanation covering causes, treatment, and prevention Links to pictures of Nail Diseases (Hardin MD/Univ of Iowa) Nail Abnormalities [en.wikipedia.org]

Infections - explanation covering causes, treatment, and prevention Links to pictures of Nail Diseases (Hardin MD/Univ of Iowa) Nail Abnormalities: Clues to Systemic Disease [en.wikipedia.org]

Junctional Epidermolysis Bullosa

abnormalities. [ncbi.nlm.nih.gov]

[…] or teeth abnormalities. [ncbi.nlm.nih.gov]

He also presented nail dystrophy and tooth abnormalities. Mucosal involvement was limited to gingival erosion. [ncbi.nlm.nih.gov]

Pallister-Hall Syndrome

Some features include extra fingers and/or toes (polydactyly), fusion of fingers and/or toes (syndactyly), abnormal nails, an abnormal growth in the brain called a hypothalamic [thinkgenetic.com]

pachyonychia abnormal thickening of the nails or claws. [medical-dictionary.thefreedictionary.com]

generalised brachytelephalangism, and nail hypoplasia should allow the delineation of Pallister-Hall syndrome, even when a CNS tumour is absent. [ncbi.nlm.nih.gov]

Plummer-Vinson Syndrome

Symptoms Difficulty swallowing Weakness Signs and tests You may develop skin and nail abnormalities thatyour doctor can see during an exam. [indiatoday.in]

Exams and Tests Your health care provider will do an exam to look for abnormal areas on your skin and nails. [account.allinahealth.org]

Your health care provider will do an exam to look for abnormal areas on your skin and nails. [eclinicalworks.adam.com]

Raynaud Syndrome

Abnormal nail-fold capillary patterns can suggest the possibility of an associated rheumatic condition. [rxlist.com]

Furthermore, capillary nail-fold abnormalities can frequently be found as described above. What specialties of doctors treat Raynaud's phenomenon? [rxlist.com]

Papillon Lefevre Disease

abnormalities PROGNOSIS Individuals with the disorder lose their primary teeth by age 5 and lose their permanent teeth during adolescence. [evolvegene.com]

Nail abnormalities. Decreased sweating. [firstskinfoundation.org]

[…] the Disorder Sparse hair Blisters on soles of feet/palms of hand (palmoplantar keratosis) Skin infections Premature tooth loss (periodontitis) Inflammation around teeth Nail [evolvegene.com]

Ichthyosis and Male Hypogonadism

abnormalities Small testes High blood sugar Diabetes mellitus Note that Ichthyosis and male hypogonadism symptoms usually refers to various symptoms known to a patient, but [checkorphan.org]

Flexures were affected, but the palms, soles, hairs and nails were spared. An X-linked ichthyosis (XLI) was suspected. [medicaljournals.se]

[…] fibrosis Telangiectasia Narrow chest Pes valgus Short foot Full cheeks Renal hypoplasia Stage 5 chronic kidney disease Limb undergrowth Rhizomelia Functional respiratory abnormality [mendelian.co]

Pretibial Dystrophic Epidermolysis Bullosa

nails due to abnormal type 7 collagen in anchoring fibrils May also get blistering of the oesophagus Generalised severe recessive (R) DEB Previously known as Hallopeau-Siemens [dermnetnz.org]

Lethal acantholytic EB• Mutation in gene for desmoplakin• AR• Present at birth, Generalized• Presence of oozing erosions than frank blisters• Abnormal nails, neonatal teeth [slideshare.net]

In most cases, nail dystrophy, especially of the toenails, is also present. [kclpure.kcl.ac.uk]

Epidermolysis Bullosa

In less severe forms of junctional EB, skin fragility is accompanied by dental enamel defects, nail abnormality and loss, and sometimes sparse hair. What are the causes? [cafamily.org.uk]

In the mildest cases, abnormal nails are the only sign of the condition. [debra.org]

Nail abnormalities along with multiple cutaneous bullae and erosions were a prominent early physical finding in this cohort, with 6 of 10 patients overall developing nail [jamanetwork.com]

Dystrophic Epidermolysis Bullosa

Abnormalities Keratosis Palmoplantaris With Arrhythmogenic Cardiomyopathy Mal De Naxos Palmoplantar Keratoderma With Arrhythmogenic Right Ventricular Cardiomyopathy And Woolly [ukgtn.nhs.uk]

abnormalities with dystrophy or loss at birth or infancy may be an isolated finding as reported in DDEB [ 26, 27 ]. [plasticsurgerykey.com]

In the mildest cases, abnormal nails are the only sign of the condition. [ghr.nlm.nih.gov]

Incontinentia Pigmenti Achromians

Hair, tooth, and nail abnormalities can also be seen. [10] Thorough dermatologic, neurologic, and ophthalmologic examinations are extremely important given the heterogeneity [ijpd.in]

Hair, tooth, and nail abnormalities can also be seen. [file.scirp.org]

Skin and nail involvements were present in the patient. (a) (b) Figure 2. Abnormally shaped and partially erupted maxillary permanent central incisors (a). [file.scirp.org]

Trichothiodystrophy Type C

abnormalities, among other symptoms. [orpha.net]

The spectrum of clinical manifestations is broad, with some patients presenting only mild hair and nail changes, but commonly consists of photosensitivity, ichtyosis, brittle [scielo.br]

The clinical appearance is always characterized by brittle and fragile hair, often combined with growth retardation and intellectual deficit, congenital ichthyosis and nail [orpha.net]

Mal de Meleda

Other features include perioral erythema, lichenoid plaques on the knees and the elbows, and nail abnormalities. [uniprot.org]

Brachydactyly with short cone-shaped fingers and nail abnormalities, such as koilonychia or pachyonychia, are frequently associated features. [jamanetwork.com]

Nail abnormalities were also observed in most of the patients and consisted of hyperconvexity and/or dystrophy, but in 5 of the patients only the toenails were affected. [jamanetwork.com]

Punctate Palmoplantar Keratoderma Type 1

abnormalities such as longitudinal fissures, onychogryphosis, and onychomadesis are frequently reported. 4,10 The course of the disease is long-term, and spontaneous resolution [mdedge.com]

Other clinical features include sclerodactyly and nail abnormalities (hypoplasia, fissuring, ridging, koilonychia). [emedicine.medscape.com]

Finally, there were no nail abnormalities. Figure 2 Clinical presentation of the PPK phenotype. [jmg.bmj.com]

Witkop Syndrome

Symptoms to look for in children: Abnormal nails Missing teeth Causes Witkop syndrome is caused by a change in the MSX1 gene located on chromosome 4p16. [nfed.org]

Witkop syndrome: A genetic disorder characterized by the absence of several teeth at birth and abnormalities of the nails. [medicinenet.com]

This is a rare syndrome among the ectodermal dysplasias in which there are abnormalities of teeth, nails, and hair with normal sweat gland function. [escholarship.org]