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6 Possible Causes for Naive CD4+ and CD8+ T Cells Decreased

  • Lymphocytopenia

    In HIV, increased activation and turnover, loss of naive cells, and decreased CD127 expression occur in both CD4 and CD8 T cells. 15 Untreated HIV-positive patients have progressive[bloodjournal.org]

  • Postpartum Psychosis

    Peripheral blood showed decreased naive CD4 and CD8 T cells, while activated CD8 and memory regulatory T cells (Tregs) were increased in women with PP as against healthy controls[ncbi.nlm.nih.gov]

  • Immunologic Deficiency Syndromes

    […] were decreased in patients with OIs; within the T cell population, the total CD4 T cell and the CD4 CD45RA CCR7 T cell naive subsets were severely decreased, whereas the[academic.oup.com] […] and natural killer populations were decreased in patients with OIs; within the T cell population, the total CD4 T cell and the CD4 CD45RA CCR7 T cell naive subsets were severely[academic.oup.com] decreased, whereas the total CD8 T cell subset was almost not modified; the B cell count was markedly decreased in patients with OIs.[academic.oup.com]

  • Amelogenesis Imperfecta Hypomaturation Type IIA5

    T cells - increased FACS central memory CD8 T cells in CD8 T cells - increased FACS effector memory CD4 T cells in CD4 T cells - increased FACS naive CD4 T cells in CD4 T[mutagenetix.utsouthwestern.edu] […] in B1 cells - decreased FACS B2 cells - decreased FACS CD4:CD8 - decreased FACS IgM MFI - increased FACS naive CD8 T cells in CD8 T cells - decreased T-dependent humoral[mutagenetix.utsouthwestern.edu] T cells - increased FACS effector memory CD4 T cells in CD4 T cells - increased FACS effector memory CD8 T cells in CD8 T cells - increased FACS naive CD8 T cells in CD8[mutagenetix.utsouthwestern.edu]

  • Premature Aging

    - and late-differentiated CD8 T cells and a decreased CD31 median florescence intensity on naive CD4 T cells of recent thymic origin.[ncbi.nlm.nih.gov] RESULTS: We found that HIV-1 disease progression is associated with a decreased CD28 median florescence intensity on CD4 and CD8 T cells; an increased proportion of intermediate[ncbi.nlm.nih.gov]

  • Immunosuppressive Drug

    Decreased CN phosphatase activity in naive CD4 T cells of dnCN Tg mice.[pubmedcentral.nih.gov] Consistent with these results, a slight but significant decrease in the TCR-induced proliferation and IL-2 production of the dnCN Tg naive T cells was noted (data not shown[pubmedcentral.nih.gov] (A) Representative CD4/CD8 profiles of thymocytes and splenocytes from 6-wk-old control littermate (LM) and heterozygous dnCN Tg / mice are shown.[pubmedcentral.nih.gov]

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