Cronkhite-Canada Syndrome
, rapidly leading to complete hair loss), and hyperpigmentation (diffuse light-to-dark brownish macules and plaques, and patchy vitiligo) distributed on the palms and soles[orpha.net]
A 66-year-old male patient presented with nausea, abdominal pain, occasional rectal bleeding, progressive dysgeusia, onicodystrophy, and alopecia.[ncbi.nlm.nih.gov]
A 64-year-old woman presented with heavy diarrhoea, nausea and weight loss accompanied by alopecia and dystrophic fingernails and toenails.[ncbi.nlm.nih.gov]
Adrenal Insufficiency
Goitre and vitiligo may also be present. Eosinophilia may also occur.[en.wikipedia.org]
We describe the case of an 83-year-old woman admitted to the emergency department due to a month's history of asthenia, weight loss, anorexia and nausea.[ncbi.nlm.nih.gov]
He had a 3-month history of left flank pain, nausea and vomiting with weight loss.[ncbi.nlm.nih.gov]
Addison's Disease
Addison's disease can present with tanning of the skin that may be patchy or even all over the body.[en.wikipedia.org]
Hyperpigmentation was observed in 76%, nausea and vomiting occurred in more than 40%, and weight loss was noted in 25%.[ncbi.nlm.nih.gov]
Primary adrenal insufficiency or Addison's disease is a rare disorder often difficult to diagnose on presentation by the nature of its associated nonspecific symptoms, such as nausea[ncbi.nlm.nih.gov]
Autoimmune Hepatitis
Some patients have other autoimmune disorders such as thyroiditis, ulcerative colitis, diabetes mellitus, vitiligo (patchy loss of skin pigmentation), or Sjogren’s syndrome[hepatitiscentral.com]
We describe a case of 40-year-old woman who presented to our hospital with symptoms of non-radiating epigastric pain for 4-5 days associated with nausea and vomiting.[ncbi.nlm.nih.gov]
For example, patients with other autoimmune diseases — thyroiditis, ulcerative colitis, diabetes mellitus, vitiligo (a patchy loss of pigment in the skin), Sjogren’s syndrome[gicare.com]
Uveomeningoencephalitic Syndrome
It is characterized by bilateral uveitis and retinal detachment and is variably associated with patchy vitiligo, alopecia, hearing loss, tinnitus, headaches, and meningismus[ajnr.org]
There may be fever, headache, nausea, meningismus, dysacusia (discomfort caused by loud noises or a distortion in the quality of the sounds being heard), tinnitus, and/or[en.wikipedia.org]
There may also be neurological signs such as severe headache, vertigo, nausea, and drowsiness.[rarediseases.org]
Hyperornithinemia-Hyperammonemia-Homocitrullinuria Syndrome
She was also noted to have patchy, symmetrical vitiligo ( Fig. 1B ). In 1992 she was referred to a psychiatrist because of complaints of fatigue and memory loss.[academic.oup.com]
Affected individuals frequently suffer from headaches, loss of appetite, nausea, and vomiting.[symptoma.com]
She had episodes of nausea and dizziness.[onlinelibrary.wiley.com]
Adrenal Gland Disease
Addison's disease can present with tanning of the skin that may be patchy or even all over the body.[en.wikipedia.org]
Black freckles Bluish-black discoloration around the nipples, mouth, rectum, scrotum, or vagina Weight loss Dehydration Loss of appetite Intense salt craving Muscle aches Nausea[stanfordchildrens.org]
Dizziness Dark skin Black freckles Bluish-black discoloration around the nipples, mouth, rectum, scrotum, or vagina Weight loss Dehydration Lack of appetite Muscle aches Nausea[jerseyshoreuniversitymedicalcenter.com]
Autosomal Recessive Spastic Paraplegia Type 23
Nausea ) Face or Mouth Disorders : Disorders that alter the faces muscles or nerves, or otherwise produce a mouth that is weakened or lower on one side, can cause drooling[familydiagnosis.com]
Vitiligo
Vitiligo is an acquired condition where there is patchy loss of melanin from the epidermis, causing areas of pale skin.[patient.info]
Where NB-UVB was compared to PUVA, the NB-UVB group reported less observations of nausea in three studies (RR 0.13, 95% CI 0.02 to 0.69; I² 0% three studies, N 156) and erythema[ncbi.nlm.nih.gov]
Vitiligo may occur in the same areas on both sides of the face or it may be patchy.[mountsinai.org]
Autoimmune Adrenal Insufficiency
Addison's disease can present with tanning of the skin that may be patchy or even all over the body.[en.wikipedia.org]
[…] type II diabetes mellitus, and premature ovarian failure (POF) presented to the Emergency Department of an academic community hospital with the one day of diffuse myalgias, nausea[shmabstracts.com]
In one dramatic case seen by the author, a known 45 year old celiac with associated hypothyroidism developed unexplained and persistent nausea and vomiting.[pubs.sciepub.com]