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11 Possible Causes for Nausea, Skeletal Dysplasia, Wide Space Between the First and Second Toe

  • Down Syndrome

    Dysplasia Society, Southeastern Regional Genetics Group Disclosure: Nothing to disclose.[emedicine.medscape.com] A 35-year-old female patient had visited another hospital for 1 month for abdominal discomfort, nausea, constipation, and palpable mass.[ncbi.nlm.nih.gov] A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org]

  • Russell-Silver Syndrome

    A new skeletal dysplasia syndrome with rhizomelia of the humeri and other malformations. Clin Genet. 1986 Jan; 29 (1):83–87. [ PubMed ] [ Google Scholar ] Adeyokunnu AA.[ncbi.nlm.nih.gov] These infrequent/rare side effects include the following: mild transient hypoglycemia; injection site reactions such as rashes; transient headaches, nausea and/or vomiting[magicfoundation.org] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Dubowitz Syndrome

    22q11.2 deletion syndrome Thanatophoric dysplasia type 2 Familial partial lipodystrophy Renal dysplasia, retinal pigmentary dystrophy, cerebellar ataxia and skeletal dysplasia[checkrare.com] Likewise, the diarrhea and nausea can be treated with over-the-counter medications, and the hyperactivity may be treated with prescription drugs, in some cases.[wisegeek.net] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Kleiner Holmes Syndrome

    Skeletal dysplasias. In: McAteer M, editor. Taybi and Lachman's radiology of syndromes, metabolic disorders, and skeletal dysplasias. 5 th ed.[ijri.org] THE ESOPHAGUS Is also known as escc; esophageal epidermoid carcinoma; esophageal squamous cell carcinoma Related symptoms: Feeding difficulties in infancy Lymphadenopathy Nausea[mendelian.co] […] gap between first and second toes Wide space between 1st, 2nd toes Wide space between first and second toes Widely spaced 1st-2nd toes Widely spaced first and second toes[rarediseases.info.nih.gov]

  • Cutis Laxa

    In the neonatal period, brachydactyly and facial dysmorphism are two early distinctive signs, later followed by intellectual disability and hyperostotic skeletal dysplasia[ncbi.nlm.nih.gov] CASE PRESENTATION A 50-year-old female with history of CL diagnosed in 1991, presented to emergency room with complaints of nausea, vomiting and abdominal distension.[academic.oup.com] Other reported osteoarticular features are: a wide space between the first and second toes; talipes equinovarus; metatarsus adductus; genu recurvatum or genu valgum; flat[scielo.br]

  • Familial Congenital Nasolacrimal Duct Obstruction

    MICROPHTHALMIA/COLOBOMA AND SKELETAL DYSPLASIA SYNDROME; MCSKS Is also known as microphthalmia or coloboma with or without rhizomelic skeletal dysplasia, microphthalmia, syndromic[mendelian.co] […] bleeding (1) Hepatitis (4) Hepatitis A (2) Hepatitis B (2) Hepatitis C (7) Hepatotoxicity (1) Intestinal obstruction (1) Irritable bowel syndrome (1) Lactose intolerance (1) Nausea[innovations.ahrq.gov] space between first and second toes (sandal toes) clinodactyly of the fifth finger All of these are found in individuals without DS.[medicalhomeportal.org]

  • Weaver Syndrome

    Key words Weaver Syndrome Accelerated skeletal maturation Bone dysplasia Congenital malformation This is a preview of subscription content, log in to check access.[link.springer.com] Any-grade AEs reported in more than 5% of patients included nausea (20%), thrombocytopenia (19%), cough (14%), diarrhea (11%), fatigue (12%), and asthenia (10%).[targetedonc.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Tricho-Oculo-Dermo-Vertebral Syndrome

    Very Small Stature, Not Skeletal Dysplasia Brachmann?[callisto.ro] Headache, blurring or dimness of vision, and sometimes dizziness or nausea may also occur. Anatomic features of the eye.[medical-dictionary.thefreedictionary.com] space between the first and second toes, and fusion of carpal and tarsal bones.[findzebra.com]

  • MORM Syndrome

    MPS IVB is characterized by skeletal changes, including short stature and skeletal dysplasia.[centogene.com] Pregnant women developing HELLP syndrome have reported experiencing one or more of these symptoms: Headache Nausea/vomiting/indigestion with pain after eating Abdominal or[preeclampsia.org] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Mild Dysmorphic Features

    This skeletal dysplasia was associated with an abnormal craniofacial development ( hypertelorism , severe microretrognathia, cleft palate , absent epiglottis , reduced number[wikigenes.org] […] reassurance Social withdrawal and increased time spent alone Symptoms of social phobia, or social anxiety, including severe blushing, sweating, shuddering, shyness, trembling or nausea[draxe.com] , fourth, and fifth fingers; feet held in eversion, prominent heels; wide space between the first and second toes; proximally placed fifth toes; hypotonia; increased skin[ssmc-tl.com]

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