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14 Possible Causes for Neck Mass, Thyroxin Binding Globulin Increased, Vocal Cord Paralysis

  • De Quervain Thyroiditis

    A 65-year-old woman presented with a hoarse voice and an enlarging tender mass in the right side of the neck.[ncbi.nlm.nih.gov] The thyroid, parathyroid, and neck masses othe than lymph nodes. In: Koss L, Melamed L, editors. Koss′ Diagnostic Cytology and its Histopathologic Basis. 5 th ed.[cytojournal.com] cord paralysis, and hypercalcemia. ( 22138076 ) Huang C....Wang X. 2012 49 What might cause pain in the thyroid gland?[malacards.org]

  • Myxedema

    There was no history suggestive of hoarseness of voice, difficulty in swallowing, mass or swelling over the neck. History of snoring was present.[casereports.in] For managing dyspnea caused by bilateral vocal cord paralysis as a complication of thyroidectomy in the acute postoperative period, reversible vocal cord lateralisation is[ncbi.nlm.nih.gov] Between 01 Jan 1989 and 30 Nov 2008 the authors performed 161 reversible and 135 irreversible vocal cord lateralisations to manage dyspnea caused by bilateral vocal cord paralysis[ncbi.nlm.nih.gov]

  • Iodine Deficiency Goiter

    […] multinodular goiter Benign thyroid tumor(s) Nodular goiter Hyperthyroidism Goiter and thyroid nodules suspicious for malignancy Malignant thyroid tumors No symptoms Local neck[endocrine.surgery.ucsf.edu] […] urinary iodine excretion (nephrosis syndrome), high thyroxine binding globuline level (hyperestrogenism, oral contraceptives), lack of selenium, latent thyroid enzyme defects[intechopen.com] This vocal cord paralysis can lead to a range of voice changes, ranging from losing a high octave or two while singing to the inability to shout to a severely disabling whisper[endocrine.surgery.ucsf.edu]

  • Subtotal Thyroidectomy

    The operation may take from 2-4 hours depending on the extent of the thyroid mass to be removed. Patients are observed for one or two days post-op.[hmcisrael.com] Operative visualization of the recurrent laryngeal nerves throughout the entire operation was important in eliminating permanent vocal cord paralysis.[journals.lww.com] Normally, thyroid hormones circulate mostly bound to protein carriers: thyroxine-binding globulin (TBG), albumin, transthyretin (TTR).[tmj.ro]

  • Postpartum Thyroiditis

    cord paralysis Hospitalization and treatment with intravenous antibiotics (nafcillin plus gentamicin or a third-generation cephalosporin); abscess formation may necessitate[aafp.org] Abstract Thyroid function during pregnancy is characterized by changes in circulating thyroid hormone concentrations related to alterations in thyroxine binding globulin ([ncbi.nlm.nih.gov] Liver disease, androgens, and nephrotic syndrome decrease thyroxine binding globulin (TBG) decreasing total thyroid hormones.[clinicaladvisor.com]

  • Familial Papillary or Follicular Thyroid Carcinoma

    Clinical Palpable neck mass (0.14% of all palpable neck masses ultimately prove to be TC).[medical-dictionary.thefreedictionary.com] Complications due to surgery and radio iodine therapy  Hypothyroidism  Dysphagia  Vocal cord paralysis  Hypoparathyroidism  Sialoadenitis because radioiodine is taken[slideshare.net] TBG (thyroxin binding globulin) increases due to stimulation from placental E2 and E3 (oestradiol and oestriol) and to reduced hepatic clearance.[ncbi.nlm.nih.gov]

  • Familial Multinodular Goiter

    mass or increased size of the neck.[endocrinediseases.org] POST OP COMPLICATIONS • Bleeding • infection • Temporary permanent loss of voice • Temppermanent hypocalcemia • Vocal cord paralysis • Need for life long thyroid supplements[slideshare.net] T3 and T4 are largely protein bound in the plasma, mainly to thyroxine-binding globulin (TBG). Only the unbound, or 'free', portion (FT3, FT4) is active.[patient.info]

  • T3 Thyrotoxicosis

    This test should be performed in all female patients with thyrotoxicosis with ovarian masses or ascites and low thyroidal radioiodide uptake.[ocw.tufts.edu] The possible complications of thyroid surgery include vocal cord paralysis and accidental removal of the parathyroid glands (located behind the thyroid gland), resulting in[emedicinehealth.com] : Normal Range: 5.0-12.0 ug/dl Increased T4 : hyperthyroidism, acute thyroiditis, increased TBG (thyroid - thyroxine binding globulin), pregnancy, contrast media with iodine[med-ed.virginia.edu]

  • Thyrotoxicosis Factitia

    Present as a rapidly enlarging bulky neck mass [ Anaplastic carcinomas usually present as a rapidly enlarging bulky neck mass.[quizlet.com] : Normal Range: 5.0-12.0 ug/dl Increased T4 : hyperthyroidism, acute thyroiditis, increased TBG (thyroid - thyroxine binding globulin), pregnancy, contrast media with iodine[med-ed.virginia.edu] Due to the risk of iatrogenic injury to the recurrent laryngeal nerve, vocal cord paralysis is also a complication of subtotal thyroidectomy.[statpearls.com]

  • Hashitoxicosis

    Hashimoto thyroiditis manifesting as a solitary cold nodule in a 34-year-old woman who complained of a palpable right-sided neck mass of 5 months duration.[pubs.rsna.org] Rapidly enlarging thyroid gland compresses neck veins, causes vocal cord paralysis, pain due to hemorrhage, often leading to an acute airway obstruction.[hyperthyroidismsymptomsx.com] Takamatsu J , Kuma K, Mozai T Journal of Clinical Endocrinology and Metabolism 62(5):980-983,1986 6 Isoelectric focusing of variant thyroxine-binding globulin in American[takamatsu.gr.jp]

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