Possible Causes for Necrolytic Migratory Erythema Glucagonoma It is marked by tumoral autonomous production of glucagon and characterized, among other symptoms, by necrolytic migratory erythema, an erythematous circinate lesion with [ncbi.nlm.nih.gov] We suggest that, in addition to the diseases listed, myelodysplastic syndrome might be able to cause necrolytic migratory erythema. [ncbi.nlm.nih.gov] Necrolytic migratory erythema is a rare skin condition that consists of migrating areas of erythema with blisters that heal with hyperpigmentation. [ncbi.nlm.nih.gov] Islet Cell Tumor These include insulinoma presenting with hyperinsulinemic hypoglycemia; glucagonoma with necrolytic migratory erythema, diabetes mellitus, and thomboembolisms; VIPoma with [orpha.net] If a glucagonoma, then necrolytic migratory erythema (classic skin condition involving face, extremities and perineum that evolves as coalescing patches of erythematous papules [cancertherapyadvisor.com] migratory erythema Diabetes mellitus Diarrhea Deep vein thrombosis Relative incidence is given as percentage of all functional pancreatic neuroendocrine tumors. [en.wikipedia.org] Zinc-Responsive Necrolytic Acral Erythema Some authors believe that NAE is a distinct entity and others consider it as a variant of necrolytic migratory erythema (NME). [ncbi.nlm.nih.gov] VARIANTS WITHOUT GLUCAGONOMA Necrolytic migratory erythema without glucagonoma. [thedoctorsdoctor.com] Necrolytic migratory erythema histopathologicalfindings. [documents.tips] Paraneoplastic Syndrome These syndromes include dermatomyositis (causing skin rash and muscle weakness), necrolytic migratory erythema (causing a red, blistering rash that spreads across the skin [moffitt.org] migratory erythema, Sweet's syndrome, Florid cutaneous papillomatosis, pyoderma gangrenosum, and acquired generalized hypertrichosis. [en.wikipedia.org] migratory erythema Glucagonoma Sweet's syndrome Florid cutaneous papillomatosis Pyoderma gangrenosum Acquired generalized hypertrichosis Hematological[20] Granulocytosis [en.wikipedia.org] Pancreatic Polypeptide Tumor Patient often present with elevated glucose and a characteristic rash called necrolytic migratory erythema seen in the face, lower abdomen, perineum, and lower extremities [uwhealth.org] erythema). [ronnyallan.com] Glucagon is measured for preoperative diagnosis of a glucagon-producing tumour of the pancreas in patients with diabetes and a characteristic skin rash (necrolytic migratory [ronnyallan.com] Erythema Elevatum Diutinum Erythema gyratum repens Necrolytic migratory erythema papulosquamous Acanthosis nigricans Ichthyosis acquisita Acrokeratosis paraneoplastica of Bazex Extramammary Paget's [en.wikipedia.org] […] marginatum · Necrolytic migratory erythema · Erythema toxicum Radiation -related disorders Sunburn · actinic rays ( Actinic keratosis, Actinic cheilitis ) · Polymorphous light [wikidoc.org] […] acral erythema 552 167 Necrolytic migratory erythema 554 168 Nephrogenic systemic fibrosis 557 169 Neurofibromatosis type 1 559 170 Nevoid basal cell carcinoma syndrome 562 [books.google.de] Malignant Neoplasm of the Pancreas migratory erythema), and anemia. [pancreaticcancer.net.au] Uomo, G. (1995) Rare presentation of endocrine pancreatic tumour: A case of glucagonoma without necrolytic migratory erythema?. [scindeks.ceon.rs] Glucagonomas produce the hormone glucagon which can result in a very striking skin rash (necrolytic migratory erythema.) [pathology.jhu.edu] Multiple Endocrine Neoplasia Type 1 Few patients show the typical skin lesions, known as necrolytic migratory erythema. [emedicine.com] migratory erythema, and weight loss. [en.wikipedia.org] A rash (necrolytic migratory erythema) that itches. [medic8.com] Celiac Disease with Diffuse Intestinal Ulceration Necrolytic migratory erythema Necrolytic migratory erythema presents as annular (ring-shaped) patches of erythema that blister, erode, and crust over. [emedicine.medscape.com] Necrolytic migratory erythema usually resolves with treatment of the underlying disease. [emedicine.medscape.com] The glucagonoma syndrome and necrolytic migratory erythema: a clinical review. Eur J Endocrinol. 2004 Nov. 151(5):531-7. [Medline]. el Darouti M, Abu el Ela M. [emedicine.medscape.com] Erythema Annulare Centrifugum […] marginatum Transient, rapidly spreading annular erythema ; specific for rheumatic fever. 161 Necrolytic migratory erythema Marker for glucagonoma ; erosive perioral and acral [dermaamin.com] Erythema migrans (marker of Lyme disease ) Erythema marginatum (rheumatic fever) Erythema gyratum repens (faster moving) Necrolytic migratory erythema (associated with glucagonomas [visualdx.com] […] acral erythema 552 167 Necrolytic migratory erythema 554 168 Nephrogenic systemic fibrosis 557 169 Neurofibromatosis type 1 559 170 Nevoid basal cell carcinoma syndrome 562 [books.google.de] Zinc Deficiency Necrolytic migratory erythema was first described in 1942 in a patient with pancreatic islet cell carcinoma. [ncbi.nlm.nih.gov] Acquired acrodermatitis enteropathica is due to zinc deficiency associated with one the following: Necrolytic migratory erythema (glucagonoma) Inadequate zinc in the diet [dermnetnz.org] migratory erythema (glucagonoma) Other websites Acrodermatitis enteropathica – Medscape Reference Books about the skin See the DermNet NZ bookstore . [dermnetnz.org] Brandt Syndrome Acquired acrodermatitis enteropathica is due to zinc deficiency associated with one the following: Necrolytic migratory erythema (glucagonoma) Inadequate zinc in the diet [dermnetnz.org] migratory erythema (glucagonoma) [13]. [dermnetnz.org] […] include necrolytic migratory erythema, necrolytic acral erythema, pellagra and essential fatty acid deficiencies. [racgp.org.au] Malnutrition A similar clinical picture to necrolytic migratory erythema can be seen with zinc deficiency or protein malnutrition, often in patients with alcoholic liver disease, in the [ncbi.nlm.nih.gov] Malnutrition-associated dermatoses including necrolytic migratory erythema (NME) and pellagra share common clinicopathological features; in particular, necrolytic changes [ncbi.nlm.nih.gov] We present a patient with a desquamating predominantly flexural erythema and glossitis due to a combination of alcoholism, zinc deficiency and amino acid deficiency. [ncbi.nlm.nih.gov] Intertrigo Perform an appropriate workup if systemic disease is suspected along with the intertrigo (eg, diabetes, acrodermatitis enteropathica, necrolytic migratory erythema secondary [emedicine.medscape.com] Linear granuloma annulare Liver palms Localized desquamation Localized granuloma annulare Micropapular weal Necrolytic migratory erythema Peeling of skin Perforating granuloma [icd9data.com] […] desquamation Infantile erythroderma, failure to thrive and diarrhea syndrome Intertrigo Intertrigo (inflammation in body folds) Intertrigo of abdominal skin fold Keratolytic winter erythema [icd9data.com] Erythema Chronicum Migrans […] systemic signs. necrolytic migratory erythema in humans, a skin disease associated with glucagon-secreting tumors of the pancreas. [medical-dictionary.thefreedictionary.com] See: illustration necrolytic migratory erythema Abbreviation: NME Red, blistering or crusting patches that appear on the skin of the buttocks, groin, lower extremities, or [medical-dictionary.thefreedictionary.com] There may also be fever, depression and anorexia. erythema multiforme major a rapidly fulminating, ulcerative form of erythema multiforme with involvement of oral mucosa and [medical-dictionary.thefreedictionary.com] Subcorneal Pustular Dermatosis migratory erythema 497 160 Nephrogenic systemic fibrosis 499 161 Neurofibromatosis type 1 501 162 Nevoid basal cell carcinoma syndrome 504 163 Nevus sebaceus 509 164 Notalgia [books.google.com] migratory erythema · Acute generalized exanthematous pustulosis PROGNOSIS AND CLINICAL COURSE SPD is a benign condition. [dermaamin.com] migratory erythema. [archives-inflammation.imedpub.com] Bazex Syndrome […] gyratum, necrolytic migratory erythema, and hypertrichosis lanuginosa acquisita. 7 The cutaneous manifestations of Bazex syndrome are paraneoplastic in that the developing [mdedge.com] Erythema gyratum repens 4. Acquired hypertrichosis 5. Ectopic ACTH 6. Necrolytic migratory erythema 7. Paget's diseases of breast 8. Paraneoplastic pemphigus 9. [studyblue.com] Cutaneous lesions, typically associated with other neoplasms than ovarian carcinoma, are amongst the ones described above: Necrolytic migratory erythema (most commonly associated [bmccancer.biomedcentral.com] GCGR-Related Hyperglucagonemia Glucagon cell adenomatosis: A new entity associated with necrolytic migratory erythema and glucagonoma syndrome. J Am Acad Dermatol. 2011 ; 65 ( 2 ): 458 – 459. 5.. [doi.org] Close clinical review revealed no evidence of necrolytic migratory erythema or hyperglycemia. 68 Ga-DOTATATE-PET showed intense diffusely increased tracer uptake throughout [doi.org] migratory erythema No No No No No Yes Diabetes No No Yes No No Yes Peripheral glucagon levels, pg/mL Elevated up to 136-fold (preoperatively) 25-fold (postoperatively) nd [doi.org] Calcinosis Circumscripta […] marginatum · Necrolytic migratory erythema · Erythema toxicum Radiation -related disorders Sunburn · actinic rays ( Actinic keratosis, Actinic cheilitis ) · Polymorphous light [wikidoc.org] […] acral erythema 552 167 Necrolytic migratory erythema 554 168 Nephrogenic systemic fibrosis 557 169 Neurofibromatosis type 1 559 170 Nevoid basal cell carcinoma syndrome 562 [books.google.it] Erythema multiforme / drug eruptions : Stevens-Johnson syndrome · Toxic epidermal necrolysis · Erythema nodosum Other erythema : Erythema annulare centrifugum · Erythema [wikidoc.org] Keratolytic Winter Erythema linear granuloma annulare, liver palms, localized desquamation, localized granuloma annulare, micropapular weal, necrolytic migratory erythema, peeling of skin, perforating [healthresearchfunding.org] Linear granuloma annulare Liver palms Localized desquamation Localized granuloma annulare Micropapular weal Necrolytic migratory erythema Peeling of skin Perforating granuloma [icd9data.com] […] infantile erythroderma failure to thrive and diarrhea syndrome, intertrigo, intertrigo (inflammation in body folds), intertrigo of abdominal skin fold, keratolytic winter erythema [healthresearchfunding.org] Pellagra Recent studies have shown that numbers of epidermal Langerhans cells decreased in other diseases caused by nutritional deficiencies, including necrolytic migratory erythema [ncbi.nlm.nih.gov] Morgan, Necrolytic Migratory Erythema, Deadly Dermatologic Diseases, 10.1007/978-3-319-31566-9_23, (143-147), (2016). [doi.org] migratory erythema. [emedicine.medscape.com] Familial Reactive Perforating Collagenosis […] acral erythema 552 167 Necrolytic migratory erythema 554 168 Nephrogenic systemic fibrosis 557 169 Neurofibromatosis type 1 559 170 Nevoid basal cell carcinoma syndrome 562 [books.google.com] Mycobacterial atypical skin infections 526 161 Mycosis fungoides and Sézary syndrome 532 162 Myiasis 538 163 Myxoid cyst 541 164 Nail psoriasis 543 165 Necrobiosis lipoidica 548 166 Necrolytic [books.google.com] Papular Urticaria […] acral erythema 552 167 Necrolytic migratory erythema 554 168 Nephrogenic systemic fibrosis 557 169 Neurofibromatosis type 1 559 170 Nevoid basal cell carcinoma syndrome 562 [books.google.es] Mycobacterial atypical skin infections 526 161 Mycosis fungoides and Sézary syndrome 532 162 Myiasis 538 163 Myxoid cyst 541 164 Nail psoriasis 543 165 Necrobiosis lipoidica 548 166 Necrolytic [books.google.es] Endocrine Dysfunction Two thirds of cases present with necrolytic migratory erythema, which is characterised by erythema and blistering over pressure points; the condition is related to zinc and [diapedia.org] Fatty Liver migratory erythema. [ncbi.nlm.nih.gov] The rarity of pseudoglucagonoma syndrome, or necrolytic migratory erythema occurring in the absence of a glucagonoma, warranted the discussion of this case. [ncbi.nlm.nih.gov] […] a 1 week history of erosive annular plaques with associated atrophy and telangiectasias on her legs bilaterally, thighs and buttock, histopathologically consistent with necrolytic [ncbi.nlm.nih.gov] Neoplasm of the Pancreas Glucagonomas produce glucagon which can result in a very striking skin rash (necrolytic migratory erythema.) [web.archive.org] Glucagonomas produce the hormone glucagon which can result in a very striking skin rash (necrolytic migratory erythema.) [pathology.jhu.edu] About 75% of glucagonomas are malignant.[ 4 ] Necrolytic migratory erythema, hyperglycemia, and venous thrombosis comprise a virtually diagnostic triad. [web.archive.org] Short Bowel Syndrome Herein, we report a case of necrolytic migratory erythema associated with malabsorption 30 years after ileocolectomy. [ncbi.nlm.nih.gov] Necrolytic migratory erythema (NME) is an uncommon inflammatory dermatosis with a distinctive clinical and histological appearance. [ncbi.nlm.nih.gov] It shows irregular erythema, bullae, erosion, crusts and pigmentation. [ncbi.nlm.nih.gov] Erythema Nodosum · Necrolytic migratory erythema · Erythema toxicum Radiation-related disorders Sunburn · actinic rays (Actinic keratosis, Actinic cheilitis) · Polymorphous light eruption [wikidoc.org] […] systemic signs. necrolytic migratory erythema in humans, a skin disease associated with glucagon-secreting tumors of the pancreas. [medical-dictionary.thefreedictionary.com] Erythema multiforme/drug eruptions: Stevens-Johnson syndrome · Toxic epidermal necrolysis · Erythema nodosum Other erythema: Erythema annulare centrifugum · Erythema marginatum [wikidoc.org] Paget Disease of the Breast Other less common pathologies also exist in the differential, such as necrolytic migratory erythema and zinc deficiency, but these are usually present as part of a largely [dermatologyadvisor.com] Umbilical Cellulitis Migratory Erythema的翻译是: [翻译] New Subtype of Solar Urticaria? [woyaofanyi.com] Captopril-Induced Late Cutaneous Eruptions的翻译是:Captopril诱发的晚皮肤爆发的Immunohistological研究 [翻译] «Bowel Bypass Syndrome»的翻译是:«Bowel Bypass Syndrome» [翻译] Glucagonoma Syndrome with Necrolytic [woyaofanyi.com]
