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8,586 Possible Causes for Necrosis

  • Sinusitis

    Tumor necrosis factor alpha (TNF-α) inhibitors have revolutionized treatment of many inflammatory diseases.[] Tissue necrosis and ulceration related to intranasal drug use should be recognized as a potential risk factor for invasive fungal sinusitis.[] Endoscopy may show mucosal necrosis (indicative of mucormycosis). Mucormycosis grows rapidly and can invade vasculature causing ischemia.[]

  • Insect Bite

    Surgical exploration revealed segmental necrosis and contracture of the superficial and deep flexors of the fingers, requiring fasciotomy and tendon-lengthening procedures[] Immunodeficient individuals may present with tissue necrosis due to an insect bite.[] In contrast, tissue necrosis and systemic symptoms do require special treatment, possibly even surgery.[]

  • Upper Respiratory Infection

    Interleukin (IL)-1 beta, IL-8, IL-6, and tumor necrosis factor-alpha (TNF-alpha) were markedly elevated in nasal lavage fluid during acute URI compared to baseline, and all[] A subset of NPS samples (n 134) was analyzed for interleukin (IL)-1β, IL-6, and tumor necrosis factor (TNF)-α concentrations.[] In diphtheria, a potent bacterial exotoxin causes local inflammation and cell necrosis.[]

  • Influenza

    Endomyocardial biopsy results yielded myocardial necrosis through complement-mediated cellular injury without evidence of interstitial infiltrates.[] It is the action of these two moieties that result in the symptoms of influenza as well as necrosis of the superficial layers of the respiratory epithelium.[]

  • Pneumonia

    Multidrug-resistant Acinetobacter baumannii (MDRAB) pneumonia with severe sepsis in a patient with rheumatoid arthritis (RA), who is predisposed after treatment with tumor necrosis[] It is characterised by progressive necrosis of lung parenchyma with cavitating foci evident upon radiological investigation.[] It is seen in patients with a compromised immune system , either from chemotherapy for cancer , HIV/AIDS , and those treated with TNF (tumor necrosis factor), such as for[]

  • Acute Bronchitis

    After treatment, the serum levels of c-reactive protein (CRP), interleukin-6 (IL-6), interleukin-8 (IL-8), and tumor necrosis factor alpha (TNF-α) of the two groups obviously[]

  • Dementia

    More recently some observational studies have suggested a protective effect from conventional synthetic disease modifying anti-rheumatic drugs (csDMARDS) and tumour necrosis[] In Binswanger disease, vascular changes observed are fibrohyalinosis of the small arteries and fibrinoid necrosis of the larger vessels inside the brain.[]

  • Streptococcal Infection

    Both the intact tubular epithelial cells and oedematous interstitium had strong positive signals, whereas only interstitial inflammation was dominant without tubular necrosis[] There was extensive necrosis of the periorbital and forehead soft tissue, requiring extensive debridement to control the invasive process.[] Bilateral renal cortical necrosis was noted in three cases (including two with bacterial embolism).[]

  • Urinary Tract Infection

    […] diabetes include renal and perirenal abscess, emphysematous pyelonephritis, emphysematous cystitis, fungal infections, xanthogranulomatous pyelonephritis, and papillary necrosis[]

  • Sunburn

    Compared with placebo, participants receiving vitamin D3 (200,000 international units) demonstrated reduced expression of proinflammatory mediators tumor necrosis factor-α[] Within an hour of UVR exposure, mast cells release preformed mediators including histamine, serotonin, and tumor necrosis factor, leading to prostaglandin and leukotriene[] Ultraviolet B irradiation of skin induces mast cell degranulation and release of tumour necrosis factor-alpha. Immunol Cell Biol . 1995 Jun. 73(3):226-33. [Medline] .[]

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