Neonatal Hemorrhage: Causes & Reasons

Possible Causes for Neonatal Hemorrhage

It is emphasized that intracranial hemorrhage due to hemophilia may occur in neonates even without a family history. [ncbi.nlm.nih.gov]

Approximately 1-2% of neonates have intracranial hemorrhage. [emedicine.medscape.com]

After neonatal period, bleeding is uncommon in infants until they become toddlers. In toddlers, trauma-related soft-tissue hemorrhage occurs. [medcaretips.com]

Hemophilia

Rescue of fatal neonatal hemorrhage in factor V deficient mice by low level transgene expression. Thromb Haemost 2000; 83 (1) 70-77 41 Mann KG. [doi.org]

Singleton TC, Keane M; Diagnostic and therapeutic challenges of intracranial hemorrhage in neonates with congenital hemophilia: a case report and review. [patient.info]

Chalmers EA; Neonatal coagulation problems. Arch Dis Child Fetal Neonatal Ed. 2004 Nov89(6):F475-8. [patient.info]

Hemophilia A

Singleton TC, Keane M ; Diagnostic and therapeutic challenges of intracranial hemorrhage in neonates with congenital hemophilia: a case report and review. [patient.info]

Approximately 1-2% of neonates have intracranial hemorrhage. Other neonates may present with severe hematoma and prolonged bleeding from the cord or umbilical area. [emedicine.medscape.com]

Chalmers EA ; Neonatal coagulation problems. Arch Dis Child Fetal Neonatal Ed. 2004 Nov89(6):F475-8. [patient.info]

Hereditary Factor XIIIA Deficiency

Umbilical cord bleeding in neonates often points to Factor XIII deficiency, while brain hemorrhages are the most common overall cause of death in this blood disorder. [ncbi.nlm.nih.gov]

The hallmark of FXIII deficiency is umbilical cord bleeding and delayed separation of the umbilical cord, which are often diagnosed in the neonatal period 12. [ejo.eg.net]

Other clinical features include delayed bleeding after trauma, cutaneous bruising and hematomas, intramuscular and joint hemorrhage, postoperative hemorrhage, impaired wound [ejo.eg.net]

Factor VII Deficiency

Clinically, the disease has been divided in four forms: (1) severe life-threatening form (15% of patients) manifesting with neonatal intracranial bleeding and often lethal [accessanesthesiology.mhmedical.com]

Early diagnosis of these hemorrhages can avoid significant long- term sequelae. [ijn.mums.ac.ir]

Intracranial hemorrhage has been reported, especially in neonates after vaginal delivery. [emedicine.medscape.com]

Ventricular Hemorrhage

Neonatal intraventricular hemorrhage Stephen L Nelson Jr MD PhD ( Dr. [medlink.com]

hemorrhage Fetal or neonatal non-traumatic intraventricular hemorrhage Intraventricular hemorrhage, grade 3, of fetus and newborn Non-traumatic intracerebral ventricular [icdlist.com]

Isolated subarachnoid bleed is more common in term infants than neonates. [sonoworld.com]

Adrenal Hemorrhage

The causes of the neonatal adrenal hemorrhages were a difficult vaginal delivery in macrosomic infant and a neonatal infection. [ncbi.nlm.nih.gov]

Neonatal adrenal hemorrhage presenting as late onset neonatal jaundice. [jiaps.com]

Neonatal adrenal hemorrhage presenting as an abdominal mass in the newborn is not uncommon. [ncbi.nlm.nih.gov]

Neonatal Intracranial Hemorrhage

Reference : Neonatal intracranial hemorrhage and phenobarbital Document type : Scientific journals : Article Discipline(s) : Human health sciences : Pediatrics To cite this [orbi.ulg.ac.be]

Intracranial hemorrhage in asymptomatic neonates: prevalence on MR images and relationship to obstetric and neonatal risk factors. Radiology. 2007;242(2):535-541. [neurologyadvisor.com]

Abstract Since the advent of modern methods of neonatal care, intracranial hemorrhage in premature infants, which is usually intraventricular, is probably not as uniformly [ncbi.nlm.nih.gov]

Other and unspecified adrenocortical insufficiency

Neonatal adrenal hemorrhage presenting as late onset neonatal jaundice. [jiaps.com]

Inguinoscrotal bruising: A sign of neonatal adrenal hemorrhage. Pediatr EmergCare2000;16:179. [sjkdt.org]

The sonographic diagnosis of neonatal adrenal hemorrhage. Radiology. 1979;131(2):453–7. PubMed Google Scholar 33. [link.springer.com]

Hemorrhagic Disease of the Newborn

hemorrhagic disease. [ncbi.nlm.nih.gov]

Neonatal adrenal hemorrhage P54.5 Neonatal cutaneous hemorrhage P54.6 Neonatal vaginal hemorrhage P54.8 Other specified neonatal hemorrhages P54.9 Neonatal hemorrhage, unspecified [icd10data.com]

[…] gastric perforation in a neonate Hemorrhagic disease of the newborn Introduction Vitamin K deficiency bleeding. [atlases.muni.cz]

Perinatal Atelectasis

Administration of vitamin K to prevent neonatal hemorrhagic disease, particularly when given in what we now know as excessive dosage, occasionally resulted in kernicterus. [books.google.com]

hemorrhage bleeding into ICD-9 Code 772.13 fetal neonatal intraventricular hemorrhage bleeding enlargement ICD-9 Code 772.14 fetal neonatal intraventricular hemorrhage bleeding [findacode.com]

P543Other neonatal gastrointestinal hemorrhage P544Neonatal adrenal hemorrhage P546Neonatal vaginal hemorrhage P548Other specified neonatal hemorrhages P549Neonatal hemorrhage [cms.gov]

Pulmonary Hemorrhage

[…] factor VII TIPP, Trial of Indomethacin Prophylaxis in Preterms Abstract Pulmonary hemorrhage in the newborn is an ominous condition that has a high neonatal mortality rate [neoreviews.aappublications.org]

The aim of this study is to evaluate the efficacy of our current management strategy for neonates with severe pulmonary hemorrhage. [ncbi.nlm.nih.gov]

Author information 1 Division of Neonatology, The University of Calgary, Calgary, AB, Canada. abhay.lodha@albertahealthservices.ca Abstract Pulmonary hemorrhage (PH) in neonates [ncbi.nlm.nih.gov]

Intracranial Hemorrhage

Abstract Intracranial hemorrhage (ICH) in neonates often results in devastating neurodevelopmental outcomes as the neonatal period is a critical window for brain development [ncbi.nlm.nih.gov]

The most feared bleeding complication in fetal and neonatal alloimmune thrombocytopenia (FNAIT) is an intracranial hemorrhage (ICH). [ncbi.nlm.nih.gov]

Six patients had grade I hemorrhage, and five of them had neonatal seizures; three had grade II hemorrhage, and all of them had neonatal seizures; one had grade II hemorrhage [scielo.br]

Subgaleal Hemorrhage

Neonatal subgaleal hemorrhage. Arch Pediatr Adolesc Med 1994;148:65-6. [ncbi.nlm.nih.gov]

[…] who require neonatal intensive care for this condition die.1 The prevalence at birth of moderate-to-severe subgaleal hemorrhages is approximately 1.5 per 10 000 births. [ncbi.nlm.nih.gov]

Birth by vacuum extraction: neonatal outcome. J Paediatr Child Health 1996;32:204-6. [PubMed] 7. Florentino-Pineda I, Ezhuthachan SG, Sineni LG, Kumar SP. [ncbi.nlm.nih.gov]

Intestinal Diverticular Hemorrhage

[…] of anus and rectum 2016 2017 2018 2019 Billable/Specific Code Type 1 Excludes gastrointestinal bleeding NOS ( K92.2 ) melena ( K92.1 ) neonatal rectal hemorrhage ( P54.2 [icd10data.com]

Hemorrhage without cc/mcc 793 Full term neonate with major problems Convert K92.2 to ICD-9-CM Code History 2016 (effective 10/1/2015) : New code (first year of non-draft ICD [icd10data.com]

Hemorrhage with mcc 378 G.i. Hemorrhage with cc 379 G.i. [icd10data.com]

Feto-Maternal Hemorrhage

To evaluate the fetal, neonatal, and long-term prognosis of massive fetomaternal hemorrhage (20 mL or more). [scienceopen.com]

When the transfused volume equals or exceeds 20 mL/kg, massive fetomaternal hemorrhage may lead to severe prenatal or neonatal complications. III. [scienceopen.com]

Fetomaternal hemorrhages of 20 mL/kg or more significantly increased the risk of fetal death, induced preterm delivery, transfer to NICU, and neonatal anemia requiring transfusion [scienceopen.com]

Intraventricular Hemorrhage of the Premature Infant

The combined exposure to intra-amniotic inflammation and neonatal respiratory distress syndrome increases the risk of intraventricular hemorrhage in preterm neonates. [scielo.org.pe]

Neurodevelopmental Outcomes of Extremely Low-Gestational-Age Neonates With Low- Grade Periventricular-Intraventricular Hemorrhage. [scielo.org.pe]

A Systematic Review and Meta-analysis of the Timing of Early Intraventricular Hemorrhage in Preterm Neonates: Clinical and Research Implications. [scielo.org.pe]

Intraventricular Hemorrhage of the Newborn Grade 1

Abstract Fetal and neonatal cerebral lesions due to hemorrhage in keeping with alloimmune thrombocytopenia require precise imaging assessment, to enable counseling and optimal [link.springer.com]

[…] cerebral hemorrhage [link.springer.com]

Elchalal U, Yagle S, Gomori JM, et al (2005) Fetal intacranial hemorrhage (fetal stroke): does grade mater? [link.springer.com]

Perinatal Intraventricular Hemorrhage

The combined exposure to intra-amniotic inflammation and neonatal respiratory distress syndrome increases the risk of intraventricular hemorrhage in preterm neonates. [scielo.org.pe]

Symptoms usually appear after the neonatal period. [analesdepediatria.org]

[…] in very preterm neonates when compared to placebo, no treatment, or heparin. [cochranelibrary.com]

Congenital Melanocytic Nevus

(hemorrhage, secondary infection, heart and renal toxicity due to the phenol, etc.). [scielo.br]

[…] literature attempting to relate the development of melanoma with these unorthodox methods of treatment,18 without counting the high risk of the procedure itself, mainly for neonates [scielo.br]

Anemia of Prematurity

Neonates with intracranial hemorrhage can lose sufficient blood into their intracranial vault to cause anemia and sometimes hemodynamic compromise (unlike older children who [msdmanuals.com]

Anemia may develop because of prenatal, perinatal (at delivery), or postpartum hemorrhage. [msdmanuals.com]

The late form occurs in exclusively breastfed neonates who do not receive vitamin K supplementation after birth. [msdmanuals.com]

Posthemorrhagic Anaemia of the Newborn

Successful resuscitation of unexpected neonatal hemorrhagic shock due to massive feto-maternal hemorrhage. Paediatr Anaesth 2008; 18 : 1004–1006. 11. [nature.com]

P541Neonatal melena P542Neonatal rectal hemorrhage P543Other neonatal gastrointestinal hemorrhage P544Neonatal adrenal hemorrhage P558Other hemolytic diseases of newborn [cms.gov]

A newborn male, born vaginally, has meconium aspiration syndrome, subarachnoid hemorrhage, and neonatal jaundice due to prematurity (delivered at 29 weeks, weighing 3 lbs, [codebusters.com]

Multifocal Dystonia

Some causes of acquired dystonia include birth injury (including hypoxia, a lack of oxygen to the brain, and neonatal brain hemorrhage), certain infections, reactions to certain [ninds.nih.gov]

Choroid Hemorrhage

Neonatal grade 1 hemorrhages have been studied extensively and have excellent prognosis [myminifellowship.com]

This study suggests that in very low-birth-weight premature neonates, the choroid plexus may be a more frequent site of intracranial hemorrhage than previously believed. [ncbi.nlm.nih.gov]

Isolated subarachnoid bleed is more common in term infants than neonates. [sonoworld.com]

Carbon Monoxide -- Teratogenic Agent

Aspirin-indomethacin Prostaglandin synthesis inhibitors Increase in gestation time prolong labor, neonatal bleeding Risk of postpartum hemorrhage CNS depressants e.g. diazepam [slideplayer.com]

morphine Interference with suckling Respiratory depression Reduced blood flow, fetal distress Sulfonamides Displacement of bilirubin from plasma protein (neonatal hyperbilirubinemia [slideplayer.com]

Neonatal Purpura Fulminans

Do new strate... 286.6 Defibrination syndrome 772.6 Cutaneous hemorrhage of fetus or newborn D65 Disseminated intravascular coagulation P54.5 Neonatal cutaneous hemorrhage [5minuteconsult.com]

In the first neonate, the acral bullous lesions turned necrotic and hemorrhagic within a day with evident gangrenous changes by day three. [ijdvl.com]

Purpura fulminans is characterized by microvascular thrombosis in the dermis followed by perivascular hemorrhage, necrosis, and minimal inflammation. [synapse.koreamed.org]

Edema of the Newborn

Inguinoscrotal bruising: a sign of neonatal adrenal hemorrhage. Pediatr Emerg Care 2000; 16 : 179. [nature.com]

[…] urticaria Sweet’s syndrome Child maltreatment Neonatal lupus Learning Point Acute hemorrhagic edema of infancy (AHEI, also called Seidlmayer or postinfectious cockade purpura [pediatriceducation.org]

Neonatal acute hemorrhagic edema of childhood: case report and review of the English-language literature. Pediatr Dermatol. 1996 Jan-Feb. 13(1):39-44. [Medline]. [emedicine.medscape.com]

Polycythemia Neonatorum

P543Other neonatal gastrointestinal hemorrhage P544Neonatal adrenal hemorrhage P546Neonatal vaginal hemorrhage P548Other specified neonatal hemorrhages P549Neonatal hemorrhage [cms.gov]

[…] specified neonatal hemorrhages P549Neonatal hemorrhage, unspecified P550Rh isoimmunization of newborn P551ABO isoimmunization of newborn P580Neonatal jaundice due to bruising [cms.gov]

Other neonatal gastrointestinal hemorrhage 其他新生兒胃腸出血 P544 Neonatal adrenal hemorrhage 新生兒腎上腺出血 P545 Neonatal cutaneous hemorrhage 新生兒皮膚出血 P546 Neonatal vaginal hemorrhage [csh.org.tw]

Neonatal Seizures

Fifteen patients with intracranial hemorrhage and neonatal seizures were identified. [ncbi.nlm.nih.gov]

Hypoxic ischemic encephalopathy is the leading cause of neonatal seizures, followed by intracranial hemorrhage, metabolic causes such as hypoglycemia and hypocalcemia, intracranial [ncbi.nlm.nih.gov]

[…] than hypocalcaemia, benign familial neonatal seizures, subarachnoid hemorrhage or stroke. [omicsonline.org]

Subperiosteal Hemorrhage

Neonatal subgaleal hemorrhage: clinical presentation, treatment, and predictors of poor prognosis. Pediatrics International, 49 (6), 903-907. Ferriero, D. M. (2004). [pedclerk.bsd.uchicago.edu]

[…] cutaneous hemorrhage 2016 2017 2018 2019 Billable/Specific Code Code on Newborn Record Applicable To Neonatal bruising Neonatal ecchymoses Neonatal petechiae Neonatal superficial [icd10data.com]

Neonatal subgaleal hemorrhage: diagnosis and management. Canadian Medical Association Journal 2001;164:1452–1453. Wolter JR. [healio.com]