Possible Causes for neonatal hyperbilirubinemia Hereditary Spherocytosis neonatal hyperbilirubinemia. [ncbi.nlm.nih.gov] The absence of a positive family history does not preclude hereditary spherocytosis as a differential for pathologic neonatal hyperbilirubinemia. [ncbi.nlm.nih.gov] HS is thought to be under diagnosed as a cause for neonatal hyperbilirubinemia. [pedclerk.bsd.uchicago.edu] Neonatal Jaundice Some of the most common causes of neonatal jaundice include Physiologic hyperbilirubinemia Breastfeeding jaundice Breast milk jaundice Pathologic hyperbilirubinemia due to [merckmanuals.com] Keywords: Fenofibrate, hyperbilirubinemia, neonatal jaundice How to cite this article: Al-Asy HM, El-Sharkawy HM, Mabrouk MM, Hamad MR. [jcnonweb.com] […] of neonatal jaundice. [aetna.com] Cholestasis The risk of developing neonatal jaundice is the same as for other babies. It is thought that there is no major damage caused to the liver of either mother or baby. [britishlivertrust.org.uk] For instance, hepatic siderosis has been documented in cases of neonatal acute liver failure. 14 Our patient’s history of coagulopathy, transaminitis, and direct hyperbilirubinemia [pediatrics.aappublications.org] Fetal Erythroblastosis Fetal and neonatal edition, 2018 May 25 [PubMed] Bilirubin Albumin Binding and Unbound Unconjugated Hyperbilirubinemia in Premature Infants., Amin SB,Wang H,, The Journal [knowledge.statpearls.com] Phototherapy for neonatal jaundice. Clin Perinatol. 1991 ; 18 : 423 – 439 10. Eggert P, Stick C, Schroder H. [pediatrics.aappublications.org] […] of pediatrics, 2018 Jan [PubMed] The Importance of Hemolysis and Its Clinical Detection in Neonates with Hyperbilirubinemia., Wong RJ,Bhutani VK,Stevenson DK,, Current pediatric [knowledge.statpearls.com] Cystic Fibrosis jaundice, average FEV1 (CF-specific percentile score ( 29 )), average BMI Z-score, age at diagnosis of CF, lung transplantation, number of pulmonary exacerbations in the [ncbi.nlm.nih.gov] […] cholelithiasis, cholecystectomy, gastroesophageal reflux, Nissen fundoplication, gastrostomy tube placement, rectal prolapse, appendiceal disease, failure to thrive, steatorrhea, neonatal [ncbi.nlm.nih.gov] Crigler-Najjar Syndrome Type 1 A neonatal hyperbilirubinemia resolved spontaneously. [ncbi.nlm.nih.gov] We have shown, for the first time, the full recovery of the lethal effects of neonatal hyperbilirubinemia. [ncbi.nlm.nih.gov] His sister, a 3-year-old girl, had a history of neonatal jaundice. [bmcpediatr.biomedcentral.com] Maternal Diabetes Syndrome High bilirubin level (hyperbilirubinemia). Immature lungs. Neonatal polycythemia (more red blood cells than normal). [medlineplus.gov] and neonatal hypoglycemia. [pharmacytimes.com] […] and maternal blood glucose levels on the OGTT, 10 but the risk of severe hyperbilirubinemia, such as seen in hemolysis, is low. 23 Neonatal respiratory distress There is [dovepress.com] Giant Cell Hepatitis Neonatal jaundice first becomes visible in the face and forehead. Blanching reveals the underlying colour. [patient.info] Idiopathic neonatal hepatitis (INH) remains a diagnosis of exclusion in the neonate with conjugated hyperbilirubinemia. [ncbi.nlm.nih.gov] A previous sibling with neonatal jaundice requiring phototherapy. Visible jaundice in the first 24 hours. Infants of mothers who have diabetes. Male infants. [patient.info] Gilbert Syndrome Sukru Aynacioglu, Reinhold Kerb, Murat Yurdakok and Atila Bozkurt, Neonatal Jaundice and Bilirubin UDP‐Glucuronosyl Transferase 1A1 Gene Polymorphism in Turkish Patients, [doi.org] Genetic interactions in the pathogenesis of neonatal hyperbilirubinemia: Gilbert's Syndrome and glucose-6-phosphate dehydrogenase deficiency. [gpnotebook.co.uk] Jaundice Detection System, Journal of Medical Systems, 40, 7, (2016). [doi.org] Rotor Syndrome A biliblanket is a portable phototherapy device for the treatment of neonatal jaundice ( hyperbilirubinemia ). [diki.pl] hyperbilirubinemia and molecular mechanisms of jaundice]. 61 Jirsa M...Sticova E 23909260 2013 24 Hereditary conjugated hyperbilirubinaemia: 37 years later. 61 Dhumeaux D [malacards.org] Keywords: Laundice, Zinc, Neonate, Hyperbilirubinemia. [ijp.mums.ac.ir] Neonatal Sepsis Late diagnosis of neonatal jaundice both increases the severity and complication. [ijp.mums.ac.ir] The distribution of 70 respondents obtained as much 15 neonates have history neonatal sepsis of which 12 neonatal jaundice and 3 not became neonatal jaundice. [eprints.ums.ac.id] Pathological neonatal jaundice can be caused by a number of factors, including: blood group incompatibility;... [evidence.nhs.uk] Thalassemia Minor Abstract Infants on this island are known to have higher incidences of neonatal hyperbilirubinemia and alpha-thalassemia minor than Caucasians. [ncbi.nlm.nih.gov] Haemolytic disease and other neonatal jaundice 196·6 (0·04%) 373·9 (0·05%) 105·6 (0·76%) 201·6 (1·00%) .. .. 373·9 (0·05%) .. [ncbi.nlm.nih.gov] jaundice, mesothelioma, unintentional suffocation, pulmonary aspiration and foreign body in trachea or lung, and foreign body in other part of body. [ncbi.nlm.nih.gov] Polycythemia Neonatorum jaundice. [pathophys.org] […] source Hyperbilirubinemia Car... 252 x 182 png 63kB pic source Kern Medical Third Yea... 762 x 529 jpeg 133kB pic source Neonatal Jaundice 1 638 x 479 jpeg 75kB pic source [mnogolok.info] […] damage P59.3 Neonatal jaundice from breast milk inhibitor P59.8 Neonatal jaundice from other specified causes P59.9 Neonatal jaundice, unspecified P60 Disseminated intravascular [icd10data.com] Cephalhematoma 抄録 So many factors as for etiology of neonatal hyperbilirubinemia have been reported by many workers. [jstage.jst.go.jp] Signs and symptoms of Neonatal Jaundice – 1. Itchy skin 2. Pale stools 3. Poor sucking / feeding 4. [indiastudychannel.com] Neonatal Jaundice Treatment & Management: Approach Considerations, Medical Care, Diet. (2018, July 25). Retrieved August 31, 2018, from 5. Shorofsky, M. [abclawcenters.com] Exchange Transfusion BACKGROUND: Exchange transfusion (ET) for severe neonatal hyperbilirubinemia (SNH) is frequently undertaken in low- and middle-income countries (LMIC), in sharp contrast to [ncbi.nlm.nih.gov] The search terms were: ‘neonatal hyperbilirubinemia', ‘neonatal jaundice', ‘exchange transfusion', ‘bilirubin encephalopathy', and/or ‘kernicterus'. [karger.com] Gartner L (1980) Chapter 6: neonatal jaundice A selected retrospective. [link.springer.com] Dubin-Johnson Syndrome We suggest ursodeoxycholic acid in treatment for Dubin-Johnson Syndrome with severe direct hyperbilirubinemia presenting in the neonatal age. [ncbi.nlm.nih.gov] Dubin-Johnson syndrome (DJS) is an autosomal recessive inherited disorder characterized by conjugated hyperbilirubinemia. Neonatal-onset DJS is rare. [ncbi.nlm.nih.gov] We suggest ursodeoxycholic acid in treatment for Dubin- Johnson Syndrome with severe direct hyperbilirubinemia presenting in the neonatal age. [degruyter.com] Congenital Hemolytic Anemia He required phototherapy for neonatal jaundice. [casesjournal.biomedcentral.com] The clinical picture of PK deficiency is variable, from hydrops fetalis to neonatal jaundice and anemia. 3 In our patient jaundice and anemia was present. [medcraveonline.com] Hemolysis Splenomegaly Neonatal jaundice [cram.com] Sickle Cell Anemia jaundice, mesothelioma, unintentional suffocation, pulmonary aspiration and foreign body in trachea or lung, and foreign body in other part of body. [ncbi.nlm.nih.gov] jaundice 64·8 (39·5 to 96·3) 19·6 (13·0 to 29·7) 70·0 ( 79·78 to 50·43) 0·9 (0·5 to 1·3) 0·3 (0·2 to 0·4) 70·6 ( 80·17 to 51·17) Other neonatal disorders 577·6 (457·5 to [ncbi.nlm.nih.gov] […] newly estimated causes with the same overall assignment of rank causes as GBD 2010: typhoid and paratyphoid separately, haemolytic disease in fetus and newborn and other neonatal [ncbi.nlm.nih.gov] Red Blood Cell Disorder Clinical description Clinically, PK-deficient patients suffer from a highly variable degree of chronic hemolysis, ranging from severe neonatal jaundice and fatal anemia at [orpha.net] Prolonged Neonatal jaundice 8. Hepatosplenomegaly 9. Hepatosplenomegaly 10. Delayed mile stones organomegaly 11. PigmentedGall stones in young Persons 12. [slideshare.net] Neonatal Meningitis Early neonatal meningitis with non-fermenting Gram negative bacilli (NFGNB) is rare, and whenever it occurrs, inanimate environment is usually implicated as the source. The authors report a case of neonatal meningitis and sepsis with Chryseobacterium indologenes, a rare non fermenting Gram negative bacterium with[…] [ncbi.nlm.nih.gov] Beta Thalassaemia Major Abstract Deferoxamine is the currently available agent for the iron-chelation therapy required by Cooley's anemia patients. The difficulties associated with parenteral administration have mandated a search for alternative therapies, especially orally active iron chelators, to remove excess iron that results in damage[…] [ncbi.nlm.nih.gov] Biliary Atresia Issues that should raise your concern: Prolonged neonatal jaundice Physiologic jaundice in healthy, full-term newborns typically resolves by the 5th or 6th day. [pedemmorsels.com] Choledochal cyst and biliary atresia are rare but important causes of neonatal jaundice. Both present with jaundice and acholic stool in neonatal period. [ncbi.nlm.nih.gov] Conjugated Hyperbilirubinemia There are other causes (ex, neonatal hepatitis), but Biliary Atresia needs to be high on your list of concerns!! [pedemmorsels.com] Congenital Pyloric Stenosis BACKGROUND: Since 1970, bupivacaine 0.25% in a dose of 4 mg x kg-1 (1.6 ml x kg-1) has been used at the Hospital Infantil de México for caudal block in children undergoing surgical correction of congenital pyloric stenosis (CPS). Although this dose is considered unsafe, in our experience, it has been associated with a[…] [ncbi.nlm.nih.gov] Pyruvate Kinase Deficiency We report an infant with neonatal hyperbilirubinemia due to pyruvate kinase deficiency. [ncbi.nlm.nih.gov] This emphasizes the need for screening neonatal hyperbilirubinemia cases in India for PK deficiency. [ncbi.nlm.nih.gov] The study detected 10 neonates with G6PD deficiency, which means that the prevalence of G6PD deficiency among Egyptian neonates with hyperbilirubinemia is 14.4% (21.2% of [ncbi.nlm.nih.gov] Kernicterus Sgro M, Campbell D, Barozzino T, Shah V: Acute neurological findings in a national cohort of neonates with severe neonatal hyperbilirubinemia. [karger.com] In 2008, national guidelines for neonatal hyperbilirubinemia were issued in Sweden. [jamanetwork.com] Chemoprevention of severe neonatal hyperbilirubinemia. Semin Perinatol. 2004 Oct. 28(5):365-8. [Medline]. Gartner LM. Neonatal jaundice. [emedicine.medscape.com] Microangiopathic Hemolytic Anemia In the neonatal period, severe hemolysis and hyperbilirubinemia can leave permanent neurological sequelae. [bioline.org.br] Congenital Hypothyroidism CASE DESCRIPTION: A female infant presenting with prolonged neonatal jaundice was found to have isolated CCH, with TSH of 2.2 mU/L (Reference range, 0.4-3.5) and free T4 of [ncbi.nlm.nih.gov] jaundice ( P55, P57 - P59 ) newborn P59.9 ICD-10-CM Diagnosis Code P59.9 Neonatal jaundice, unspecified 2016 2017 2018 2019 Billable/Specific Code Code on Newborn Record [icd10data.com] Applicable To Myxedema NOS congenital E03.1 Jaundice (yellow) R17 ICD-10-CM Diagnosis Code R17 Unspecified jaundice 2016 2017 2018 2019 Billable/Specific Code Type 1 Excludes neonatal [icd10data.com] Neonatal Intracranial Hemorrhage This added burden of bilirubin may cause sufficient neonatal hyperbilirubinemia to require phototherapy and, rarely, exchange transfusion. No other treatment is needed. [merckmanuals.com] Fetal/neonatal injuries include scalp lacerations and bruising, SGH, cephalohematoma, intracranial hemorrhage, neonatal jaundice, subconjunctival and retinal hemorrhage, shoulder [ispub.com] Congenital Toxoplasmosis Mediators Inflamm. 2014;2014:910621. doi: 10.1155/2014/910621. Epub 2014 Sep 18. Machado AS 1, Carneiro AC 1, Béla SR 2, Andrade GM 3, Vasconcelos-Santos DV 4, Januário JN 5, Coelho-dos-Reis JG 2, Ferro EA 6, Teixeira-Carvalho A 2, Vitor RW 1, Martins-Filho OA 2 ; Ufmg Congenital Toxoplasmosis Brazilian Group -UFMG-CTBG 5.[…] [ncbi.nlm.nih.gov] Glycogen Storage Disease Type 1 Glycogen storage disease type 1 (GSD1) is an inborn error of metabolism caused by deficiency of glucose-6-phosphatase, the enzyme catalysing the conversion of glucose-6-phosphate (G6P) to glucose. GSD1 is associated with severe hyperlipidaemia and hepatic steatosis. The underlying mechanisms responsible for these[…] [ncbi.nlm.nih.gov]
