Neonatal Jaundice: Causes & Reasons

Warning: Do not use in emergencies, if pregnant, if under 18, or as a substitute for a doctor’s advice or diagnosis. Learn more

Possible Causes for Neonatal Jaundice

Neonatal Jaundice

BACKGROUND: Neonatal jaundice affects one in two infants globally. [ncbi.nlm.nih.gov]

Background: Neonatal jaundice is a common problem in newborns. Inadequate breastfeeding jaundice is an important consideration for the neonatal jaundice. [ncbi.nlm.nih.gov]

Abstract Phototherapy has been widely used in treating neonatal jaundice, but detailed metabonomic profiles of neonatal jaundice patients and response to phototherapy have [ncbi.nlm.nih.gov]

Hereditary Spherocytosis

In this article the authors present a case of pathological neonatal jaundice resistant to phototherapy in a baby with a family history of Gilbert's syndrome and hereditary [ncbi.nlm.nih.gov]

ICD-10-CM Diagnosis Code P59.9 Neonatal jaundice, unspecified 2016 2017 2018 2019 Billable/Specific Code Code on Newborn Record Applicable To Neonatal physiological jaundice [icd10data.com]

(yellow) R17 ICD-10-CM Diagnosis Code R17 Unspecified jaundice 2016 2017 2018 2019 Billable/Specific Code Type 1 Excludes neonatal jaundice ( P55, P57 - P59 ) newborn P59.9 [icd10data.com]

Fetal Erythroblastosis

The newborn can present with a number of features including: clinical evidence of a fetal anemia neonatal jaundice neonatal hepatosplenomegaly generalized body edema The condition [radiopaedia.org]

After birth, however, the immature neonatal liver is not capable of handling a high bilirubin load and this can result in severe neonatal jaundice. [patient.info]

Other causes of neonatal jaundice Intrauterine congenital infections (syphilis, cytomegalovirus, parvovirus). Erythrocyte membrane defects. [patient.info]

Giant Cell Hepatitis

Infants with this condition are usually jaundiced. Jaundice that is caused by neonatal hepatitis is not the same as physiologic neonatal jaundice. [en.wikipedia.org]

Abstract It is important to distinguish neonatal hepatitis (NH) from extra hepatic biliary atresia (EHBA) in a neonate presented with jaundice as the former is purely medical [ncbi.nlm.nih.gov]

P59.29 P58.41 Neonatal jaundice due to drugs or toxins transmitted from mother P58.42 Neonatal jaundice due to drugs or toxins given to newborn P58.5 Neonatal jaundice due [icd10data.com]

Polycythemia Neonatorum

[…] damage P59.3 Neonatal jaundice from breast milk inhibitor P59.8 Neonatal jaundice from other specified causes P59.9 Neonatal jaundice, unspecified P60 Disseminated intravascular [icd10data.com]

Gallery images and information: Diagnosis Polycythemia Neonatorum pic source Neonatal Jaundice 1 638 x 479 jpeg 79kB pic source Neonatal Jaundice 1 638 x 479 jpeg 54kB pic [mnogolok.info]

P39.4 Neonatal skin infection Inclusion: Neonatal pyoderma| excludes: pemphigus neonatorum (L00)| staphylococcal scalded skin syndrome (L00)| P58.3 Neonatal jaundice due [codelay.com]

Biliary Atresia

Choledochal cyst and biliary atresia are rare but important causes of neonatal jaundice. Both present with jaundice and acholic stool in neonatal period. [ncbi.nlm.nih.gov]

METHODS: Twenty children with neonatal jaundice and no drainage as shown on the HIDA scan underwent a diagnostic laparoscopy through an umbilical 5 mm port. [ncbi.nlm.nih.gov]

Issues that should raise your concern: Prolonged neonatal jaundice Physiologic jaundice in healthy, full-term newborns typically resolves by the 5th or 6th day. [pedemmorsels.com]

Kernicterus

jaundice due to other excessive hemolysis P58.0 Neonatal jaundice due to bruising P58.1 Neonatal jaundice due to bleeding P58.2 Neonatal jaundice due to infection P58.3 Neonatal [icd10data.com]

Clinical experience with Sephadex gel filtration for evaluation of the bilirubin binding affinity of serum in neonatal jaundice is reported. [ncbi.nlm.nih.gov]

Osborn LM, Reiff MI, Bolus R: Jaundice in the full-term neonate. Pediatrics 1984;73:520–525. [karger.com]

Congenital Hemolytic Anemia

He required phototherapy for neonatal jaundice. [casesjournal.biomedcentral.com]

Clinical description Clinically, PK-deficient patients suffer from a highly variable degree of chronic hemolysis, ranging from severe neonatal jaundice and fatal anemia at [orpha.net]

The clinical picture of PK deficiency is variable, from hydrops fetalis to neonatal jaundice and anemia. 3 In our patient jaundice and anemia was present. [medcraveonline.com]

Neonatal Sepsis

The distribution of 70 respondents obtained as much 15 neonates have history neonatal sepsis of which 12 neonatal jaundice and 3 not became neonatal jaundice. [eprints.ums.ac.id]

Jaundice in the newborn breastfed babies. Pathological neonatal jaundice can be caused by a number of factors, including: blood group incompatibility;... [evidence.nhs.uk]

Late diagnosis of neonatal jaundice both increases the severity and complication. [ijp.mums.ac.ir]

Niemann-Pick Disease Type C

[…] type C (NP-C) is a lysosomal lipid storage disease (see this term) characterized by variable clinical signs, depending on the age of onset, such as prolonged unexplained neonatal [orpha.net]

We report the case of a Russian newborn with early-infantile onset Niemann-Pick disease type C who displayed prolonged neonatal jaundice and hepatosplenomegaly. [ncbi.nlm.nih.gov]

jaundice or cholestasis, isolated unexplained splenomegaly, and progressive, often severe neurological symptoms such as cognitive decline, cerebellar ataxia, vertical supranuclear [orpha.net]

Congenital Hypothyroidism

CASE DESCRIPTION: A female infant presenting with prolonged neonatal jaundice was found to have isolated CCH, with TSH of 2.2 mU/L (Reference range, 0.4-3.5) and free T4 of [ncbi.nlm.nih.gov]

ICD-10-CM Diagnosis Code P59.9 Neonatal jaundice, unspecified 2016 2017 2018 2019 Billable/Specific Code Code on Newborn Record Applicable To Neonatal physiological jaundice [icd10data.com]

(yellow) R17 ICD-10-CM Diagnosis Code R17 Unspecified jaundice 2016 2017 2018 2019 Billable/Specific Code Type 1 Excludes neonatal jaundice ( P55, P57 - P59 ) newborn P59.9 [icd10data.com]

Biliary Tree Disease

[…] obstructive Neonatal cholestasis North American Indian intrahepatic cholestasis Obstructive hyperbilirubinemia Obstructive jaundice Papillary mass of biliary tract Postpartum [icd9data.com]

(inflammatio of wall of bile ducts with entry of neutrophils into lumen). - sepsis dominates clinical picture. 1/3 of neonatal cholestasis. complete or partial obstruction [quizlet.com]

[…] extrahepatic and intrahepatic o Multiple cystic dilatations only of intrahepatic bile ducts (corresponds to Caroli disease, see Digestive Pathology lecture #6) - May cause: o Neonatal [medschool.lsuhsc.edu]

Congenital Liver Cirrhosis

Explain why fractionation of serum bilirubin is necessary in infants who remain jaundiced after 2 weeks of age. [pedsinreview.aappublications.org]

Keywords: Autopsy; Cholestatic Jaundice; Neonate. [indianpediatrics.net]

Characterize the syndrome of “neonatal hepatitis” and explain how it differs from viral hepatitis. [pedsinreview.aappublications.org]

TORCH Syndrome

IUGR), jaundice, hepatosplenomegaly, elevated transaminase concentrations, and thrombocytopenia. [pedsinreview.aappublications.org]

They include hepatosplenomegaly (enlargement of the liver and spleen), fever, lethargy, difficulty feeding, anemia, petechiae, purpurae, jaundice, and chorioretinitis. [en.wikipedia.org]

[…] system [CNS] manifestations, early jaundice, and low platelets), hence the usefulness of the TORCH concept. [accesspediatrics.mhmedical.com]

Acute Hepatic Porphyria

Its clinical presentation is distinct from that of classic HCP and includes neonatal hemolytic anemia, neonatal jaundice, and mild chronic anemia during childhood and adulthood [scielo.br]

Gaucher Disease Type 2

NP-C can present in the neonatal period with fetal hydrops and cholestatic jaundice. [ncbi.nlm.nih.gov]

Hereditary North American Indian Childhood Cirrhosis

Manifesting first as transient neonatal jaundice, the disease evolves into periportal fibrosis and cirrhosis during a period ranging from childhood to adolescence. [orpha.net]

jaundice advances over time to biliary cirrhosis with severe liver fibrosis.[1] Eventually, liver failure occurs, and requires liver transplantation.[1] References[edit] [en.wikipedia.org]

The disease typically presents, in a child who is otherwise well, with transient neonatal jaundice that progresses to biliary cirrhosis requiring hepatic transplantation in [humpath.com]

Exchange Transfusion

Neonatal hemolytic diseases. Journal of Organization of Blood Transfusion 2000; 19: 1-3. 14. Lucus GN. Neonatal Jaundice due to ABO-in compatibility in Sirilanka. [jpma.org.pk]

Gartner L (1980) Chapter 6: neonatal jaundice A selected retrospective. [link.springer.com]

[…] for neonatal jaundice do not exist in the vast majority of LMIC. [karger.com]

Mucopolysaccharidosis

Abstract Mucopolysaccharidosis Type II (Hunter syndrome) is a rare X-linked recessive storage disorder caused by deficiency of lysosomal enzyme iduronate-2-sulfatase, causing excess accumulation of glycosaminoglycans in the lysosomes resulting in cellular damage, organ failure and death. Severe subtype develops[…] [ncbi.nlm.nih.gov]

Cholestatic Jaundice

Risk of kernicterus in newborns with neonatal jaundice References:[1] We list the most important complications. The selection is not exhaustive. [amboss.com]

"An osteopathic approach to reduction of readmissions for neonatal jaundice". [en.m.wikipedia.org]

jaundice Liver disease: hepatitis (e.g., viral, autoimmune, toxic/alcoholic), cirrhosis, Wilson disease Hyperthyroidism Conjugated hyperbilirubinemia Decreased excretion/ [amboss.com]

Gaucher Disease

Summary Epidemiology The prevalence is approximately 1/100,000. The annual incidence of GD in the general population is about 1/60,000, but it can reach up to 1/1,000 in Ashkenazi Jewish populations. Clinical description The clinical manifestations of this disease are highly variable. GD type 1 (90% of cases) is the chronic[…] [orpha.net]

Myxedema

Myxedema coma occurs as a result of long-standing, undiagnosed, or undertreated hypothyroidism and is usually precipitated by a systemic illness. Myxedema coma can result from any of the causes of hypothyroidism, most commonly chronic autoimmune thyroiditis. It can also occur in patients who had thyroidectomy or[…] [emedicine.com]

Crigler-Najjar Syndrome Type 1

Physiological neonatal jaundice may peak at 85–170 µmol/l and decline to normal adult concentrations within two weeks. Prematurity results in higher levels. [en.wikipedia.org]

jaundice, unspecified 2016 2017 2018 2019 Billable/Specific Code Code on Newborn Record Applicable To Neonatal physiological jaundice (intense)(prolonged) NOS due to or associated [icd10data.com]

Differential diagnosis [ edit ] Neonatal jaundice may develop in the presence of sepsis, hypoxia, hypoglycemia, hypothyroidism, hypertrophic pyloric stenosis, galactosemia [en.wikipedia.org]

Gilbert Syndrome

The role of GS in neonatal jaundice is unknown. [ncbi.nlm.nih.gov]

Sukru Aynacioglu, Reinhold Kerb, Murat Yurdakok and Atila Bozkurt, Neonatal Jaundice and Bilirubin UDP‐Glucuronosyl Transferase 1A1 Gene Polymorphism in Turkish Patients, [doi.org]

Although peak jaundice levels did not differ among groups, newborn infants with the molecular marker for GS have an accelerated increase in neonatal jaundice during the first [ncbi.nlm.nih.gov]

Rotor Syndrome

A biliblanket is a portable phototherapy device for the treatment of neonatal jaundice ( hyperbilirubinemia ). [diki.pl]

Serum levels of zinc and bilirubin were compared for 114 neonates without jaundice jaundice(control group) and 149 neonates with jaundice (case group) using atomic absorption [ijp.mums.ac.ir]

Inheritance: autosomal recessive Clinical features Excessive, persistent neonatal jaundice Neurological symptoms caused by kernicterus Diagnosis ↑↑ Indirect bilirubin (20– [amboss.com]

AMACR Deficiency

Patients manifest neonatal jaundice, intrahepatic cholestasis and bile duct deficiency. [uniprot.org]

Clinical features include neonatal jaundice, intrahepatic cholestasis, bile duct deficiency and absence of cholic acid from bile. [labome.com]

Clinical features include neonatal jaundice, severe intrahepatic cholestasis, cirrhosis. [malacards.org]

Alagille Syndrome

Besides causing neonatal jaundice, it affects many body systems and is associated with pulmonary valvular stenosis, peripheral pulmonary stenosis, deep-set eyes with anterior [medical-dictionary.thefreedictionary.com]

Neonatal cholestatic jaundice was associated with poorer survival with native liver (p=0.0004). [gut.bmj.com]

Clinical findings Stunted growth, neonatal jaundice, hepatomegaly, fat deposits in skin, facial, heart, eye, vertebrae, kidney defects, characteristic faces, cardiac malformations [medical-dictionary.thefreedictionary.com]

Mucopolysaccharidosis Type 7

At Pappas Capital, we are dedicated to furthering life science discoveries and bringing groundbreaking solutions to market. 05.09.2019 Montreal and Charlotte, NC, May 8, 2019 — Milestone Pharmaceuticals ... Read More Pappas Capital is laser focused on the life science sector. For nearly 25 years we have been investing[…] [pappasventures.com]

Glucose-6-Phosphate Dehydrogenase Deficiency

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the commonest enzyme disorder of human beings and a globally important cause of neonatal jaundice, which can lead to [ncbi.nlm.nih.gov]

BACKGROUND: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-linked disorder which causes neonatal jaundice in most cases, and under certain conditions, can cause [ncbi.nlm.nih.gov]

Although most affected individuals are asymptomatic, there is a risk of neonatal jaundice and acute haemolytic anaemia, triggered by infection and the ingestion of certain [ncbi.nlm.nih.gov]

Favism

There was no family history of favism or neonatal jaundice. The baby received transfusions and the parents were advised about the food and drugs to be avoided. [imagebank.hematology.org]