Neonatal Jaundice: Causes & Reasons

Possible Causes for Neonatal Jaundice

[…] understood, development of a genetic test panel for risk of severe and/or prolonged neonatal jaundice may become feasible. [7] Once excreted into bile and transferred to [emedicine.medscape.com]

Treatment of neonatal jaundice was the focus of the second study. [acutecaretesting.org]

[…] for neonatal jaundice. [emedicine.medscape.com]

Hereditary Spherocytosis

In this article the authors present a case of pathological neonatal jaundice resistant to phototherapy in a baby with a family history of Gilbert's syndrome and hereditary [ncbi.nlm.nih.gov]

We evaluated a neonate with severe jaundice but a negative family history. [ncbi.nlm.nih.gov]

ICD-10-CM Diagnosis Code P59.9 Neonatal jaundice, unspecified 2016 2017 2018 2019 Billable/Specific Code Code on Newborn Record Applicable To Neonatal physiological jaundice [icd10data.com]

Giant Cell Hepatitis

P59.29 P58.41 Neonatal jaundice due to drugs or toxins transmitted from mother P58.42 Neonatal jaundice due to drugs or toxins given to newborn P58.5 Neonatal jaundice due [icd10data.com]

Neonatal jaundice first becomes visible in the face and forehead. Blanching reveals the underlying colour. [patient.info]

jaundice from other and unspecified causes P59.0 Neonatal jaundice associated with preterm delivery P59.1 Inspissated bile syndrome P59.2 Neonatal jaundice from other and [icd10data.com]

Polycythemia Neonatorum

Gallery images and information: Diagnosis Polycythemia Neonatorum pic source Neonatal Jaundice 1 638 x 479 jpeg 79kB pic source Neonatal Jaundice 1 638 x 479 jpeg 54kB pic [mnogolok.info]

[…] damage P59.3 Neonatal jaundice from breast milk inhibitor P59.8 Neonatal jaundice from other specified causes P59.9 Neonatal jaundice, unspecified P60 Disseminated intravascular [icd10data.com]

Jaundice charts - Neon... 1242 x 864 jpeg 252kB pic source Neonatal Jaundice 1 638 x 479 jpeg 87kB pic source Candidiasis symptoms m... 236 x 177 jpeg 10kB pic source Hepatosplenomegaly [mnogolok.info]

Fetal Erythroblastosis

The newborn can present with a number of features including: clinical evidence of a fetal anemia neonatal jaundice neonatal hepatosplenomegaly generalized body edema The condition [radiopaedia.org]

After birth, however, the immature neonatal liver is not capable of handling a high bilirubin load and this can result in severe neonatal jaundice. [patient.info]

Epidemiology of neonatal jaundice in the Jerusalem population. [doi.org]

Kernicterus

Clinical experience with Sephadex gel filtration for evaluation of the bilirubin binding affinity of serum in neonatal jaundice is reported. [ncbi.nlm.nih.gov]

[…] return to top Physiological Jaundice Most of the cases of neonatal jaundice is physiological in nature and is not worrisome. [sharinginhealth.ca]

Indirect hyperbilirubinemia in the neonate. In: Maisels MJ, Watchko JF, editors. Neonatal Jaundice. [dovepress.com]

Biliary Atresia

Choledochal cyst and biliary atresia are rare but important causes of neonatal jaundice. Both present with jaundice and acholic stool in neonatal period. [ncbi.nlm.nih.gov]

METHODS: Twenty children with neonatal jaundice and no drainage as shown on the HIDA scan underwent a diagnostic laparoscopy through an umbilical 5 mm port. [ncbi.nlm.nih.gov]

Issues that should raise your concern: Prolonged neonatal jaundice Physiologic jaundice in healthy, full-term newborns typically resolves by the 5th or 6th day. [pedemmorsels.com]

Congenital Hemolytic Anemia

He required phototherapy for neonatal jaundice. [casesjournal.biomedcentral.com]

Clinical description Clinically, PK-deficient patients suffer from a highly variable degree of chronic hemolysis, ranging from severe neonatal jaundice and fatal anemia at [orpha.net]

The clinical picture of PK deficiency is variable, from hydrops fetalis to neonatal jaundice and anemia. 3 In our patient jaundice and anemia was present. [medcraveonline.com]

Niemann-Pick Disease Type C

[…] type C (NP-C) is a lysosomal lipid storage disease (see this term) characterized by variable clinical signs, depending on the age of onset, such as prolonged unexplained neonatal [orpha.net]

We report the case of a Russian newborn with early-infantile onset Niemann-Pick disease type C who displayed prolonged neonatal jaundice and hepatosplenomegaly. [ncbi.nlm.nih.gov]

jaundice or cholestasis, isolated unexplained splenomegaly, and progressive, often severe neurological symptoms such as cognitive decline, cerebellar ataxia, vertical supranuclear [orpha.net]

Neonatal Sepsis

The distribution of 70 respondents obtained as much 15 neonates have history neonatal sepsis of which 12 neonatal jaundice and 3 not became neonatal jaundice. [eprints.ums.ac.id]

Late diagnosis of neonatal jaundice both increases the severity and complication. [ijp.mums.ac.ir]

Jaundice in the newborn breastfed babies. Pathological neonatal jaundice can be caused by a number of factors, including: blood group incompatibility;... [evidence.nhs.uk]

Congenital Hypothyroidism

CASE DESCRIPTION: A female infant presenting with prolonged neonatal jaundice was found to have isolated CCH, with TSH of 2.2 mU/L (Reference range, 0.4-3.5) and free T4 of [ncbi.nlm.nih.gov]

ICD-10-CM Diagnosis Code P59.9 Neonatal jaundice, unspecified 2016 2017 2018 2019 Billable/Specific Code Code on Newborn Record Applicable To Neonatal physiological jaundice [icd10data.com]

(yellow) R17 ICD-10-CM Diagnosis Code R17 Unspecified jaundice 2016 2017 2018 2019 Billable/Specific Code Type 1 Excludes neonatal jaundice ( P55, P57 - P59 ) newborn P59.9 [icd10data.com]

Biliary Tree Disease

[…] obstructive Neonatal cholestasis North American Indian intrahepatic cholestasis Obstructive hyperbilirubinemia Obstructive jaundice Papillary mass of biliary tract Postpartum [icd9data.com]

(inflammatio of wall of bile ducts with entry of neutrophils into lumen). - sepsis dominates clinical picture. 1/3 of neonatal cholestasis. complete or partial obstruction [quizlet.com]

[…] extrahepatic and intrahepatic o Multiple cystic dilatations only of intrahepatic bile ducts (corresponds to Caroli disease, see Digestive Pathology lecture #6) - May cause: o Neonatal [medschool.lsuhsc.edu]

Mucopolysaccharidosis Type 7

Neonatal jaundice or the yellowing of the skin may occur. Children with more mild cases of MPS VII begin to show symptoms in early childhood. [rarediseases.org]

We report a neonate with MPS type VII who presented with significant cholestatic jaundice and hepatosplenomegaly and provide a review of the literature. [journals.lww.com]

The clinical jaundice described in only five of the reported cases of MPS type VII is not well defined. [journals.lww.com]

Congenital Liver Cirrhosis

Explain why fractionation of serum bilirubin is necessary in infants who remain jaundiced after 2 weeks of age. [pedsinreview.aappublications.org]

Keywords: Autopsy; Cholestatic Jaundice; Neonate. [indianpediatrics.net]

Characterize the syndrome of “neonatal hepatitis” and explain how it differs from viral hepatitis. [pedsinreview.aappublications.org]

TORCH Syndrome

IUGR), jaundice, hepatosplenomegaly, elevated transaminase concentrations, and thrombocytopenia. [pedsinreview.aappublications.org]

[…] system [CNS] manifestations, early jaundice, and low platelets), hence the usefulness of the TORCH concept. [accesspediatrics.mhmedical.com]

They include hepatosplenomegaly (enlargement of the liver and spleen), fever, lethargy, difficulty feeding, anemia, petechiae, purpurae, jaundice, and chorioretinitis. [en.wikipedia.org]

Alpha-1 Antitrypsin Deficiency

"An osteopathic approach to reduction of readmissions for neonatal jaundice". [en.wikipedia.org]

Neonates with A1AT deficiency may present with neonatal jaundice and hepatitis; older children may develop hepatitis, cirrhosis and liver failure due to A1AT deficiency. [patient.info]

Severe (ZZ) AATD can also lead to neonatal jaundice and hepatitis in infancy and childhood that typically resolves before returning in a subset of individuals in the fourth [aacc.org]

Gaucher Disease Type 2

NP-C can present in the neonatal period with fetal hydrops and cholestatic jaundice. [ncbi.nlm.nih.gov]

Zellweger Syndrome

Neonatal seizures are frequent. Liver dysfunction may be evident as neonatal jaundice and elevation in liver function tests. [path.upmc.edu]

neonatal jaundice Prolonged yellowing of skin in newborn 0006579 Protruding tongue Prominent tongue Tongue sticking out of mouth [ more ] 0010808 Pulmonary hypoplasia Small [rarediseases.info.nih.gov]

[…] stroma 0007759 Optic disc pallor 0000543 Patent ductus arteriosus 0001643 Pigmentary retinopathy 0000580 Posteriorly rotated ears Ears rotated toward back of head 0000358 Prolonged [rarediseases.info.nih.gov]

Hereditary North American Indian Childhood Cirrhosis

Manifesting first as transient neonatal jaundice, the disease evolves into periportal fibrosis and cirrhosis during a period ranging from childhood to adolescence. [orpha.net]

jaundice advances over time to biliary cirrhosis with severe liver fibrosis.[1] Eventually, liver failure occurs, and requires liver transplantation.[1] References[edit] [en.wikipedia.org]

[…] codes for cirhin.[2] NAIC is a ribosomopathy.[3][4] An R565W mutation of CIRH1A[2][5] leads to partial impairment of cirhin interaction with NOL11.[5] Initial transient neonatal [en.wikipedia.org]

Acute Hepatic Porphyria

April 09, 2019; 92 (15 Supplement) May 7, 2019, Sean R. Rudnick, Madeline Merkel, John J. Ko, Barbara H. Johnson, Virginia Noxon, Ashley L. Cole, Sonalee Agarwal First published April 16, 2019, Abstract Objective: This study’s objective was to follow AHP/AIP patients’ healthcare journeys from first suspected symptom to[…] [n.neurology.org]

Mucopolysaccharidosis

Definition: Systemic lysosomal storage disease caused by a deficiency of alpha-L-iduronidase ( IDURONIDASE ) and characterized by progressive physical deterioration with urinary excretion of DERMATAN SULFATE and HEPARAN SULFATE. There are three recognized phenotypes representing a spectrum of clinical severity[…] [hon.ch]

Exchange Transfusion

[…] should not be discounted. [32] The purpose of treating neonatal jaundice is to avoid neurotoxicity. [emedicine.medscape.com]

Gartner L (1980) Chapter 6: neonatal jaundice A selected retrospective. [link.springer.com]

Guidelines for management of neonatal jaundice currently in use in all pediatric departments in Norway. [emedicine.medscape.com]

Gaucher Disease

Gaucher's disease Acid beta-glucosidase Specialty Endocrinology Gaucher's disease or Gaucher disease () (GD) is a genetic disorder in which glucocerebroside (a sphingolipid, also known as glucosylceramide) accumulates in cells and certain organs. The disorder is characterized by bruising, fatigue, anemia, low blood[…] [en.wikipedia.org]

Myxedema

Ureteral myxedema is exceptionally rare. We describe computed tomography and magnetic resonance imaging findings in a case of ureteral myxedema. The demonstration of water-like hyperintensity around the ureteral lumen on heavily T2-weighted sequences should be considered a strongly suggestive sign for ureteral[…] [ncbi.nlm.nih.gov]

Cholestatic Jaundice

Neonatal obstructive jaundice causedby a malpositioned gastrostomy tube. AJR 2005;184:S132–3. Konda J, Ruggle P. [tropicalgastro.com]

Surgical causes of jaundice in neonates are biliary atresia, inspissated bile syndrome, intrahepatic hypoplasia, choledochal cyst, Caroli's disease and spontaneous perforation [ncbi.nlm.nih.gov]

Research ArticlePractice Test at 2 weeks Canadian Family Physician December 2009, 55 (12) 1184-1192; Article Figures & Data Figure 1 Algorithm for investigation of the neonate [cfp.ca]

Crigler-Najjar Syndrome Type 1

Neonatal jaundice and Gilbert syndrome are common causes of unconjugated hyperbilirubinemia. [pubmed.ncbi.nlm.nih.gov]

jaundice, unspecified 2016 2017 2018 2019 Billable/Specific Code Code on Newborn Record Applicable To Neonatal physiological jaundice (intense)(prolonged) NOS due to or associated [icd10data.com]

Differential diagnosis Other causes of neonatal jaundice, including: Gilbert's syndrome. Haemolysis. Inconsequential neonatal jaundice. Breast-milk jaundice. [patient.info]

Gilbert Syndrome

The role of GS in neonatal jaundice is unknown. [ncbi.nlm.nih.gov]

Sukru Aynacioglu, Reinhold Kerb, Murat Yurdakok and Atila Bozkurt, Neonatal Jaundice and Bilirubin UDP‐Glucuronosyl Transferase 1A1 Gene Polymorphism in Turkish Patients, [doi.org]

Although peak jaundice levels did not differ among groups, newborn infants with the molecular marker for GS have an accelerated increase in neonatal jaundice during the first [ncbi.nlm.nih.gov]

Cerebrotendinous Xanthomatosis

Neonatal cholestatic jaundice and infantile-onset diarrhea with failure to thrive may be the earliest clinical manifestation (15-17). [ncbi.nlm.nih.gov]

The symptoms typically appear in infancy, including intractable diarrhea, neonatal jaundice, or cholestasis. [ncbi.nlm.nih.gov]

In childhood, the earliest manifestations may be infantile diarrhea and neonatal cholestatic jaundice. [ncbi.nlm.nih.gov]

Glucose-6-Phosphate Dehydrogenase Deficiency

In the case of neonatal jaundice, phototherapy should be initiated immediately and bilirubin levels should be monitored closely. [cancertherapyadvisor.com]

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the commonest enzyme disorder of human beings and a globally important cause of neonatal jaundice, which can lead to [ncbi.nlm.nih.gov]

G6PD deficiency is found to one important cause of neonatal jaundice developing on day 2 onwards. [ncbi.nlm.nih.gov]

Favism

Prolonged neonatal jaundice is serious and should be followed up promptly. [en.wikipedia.org]

There was no family history of favism or neonatal jaundice. The baby received transfusions and the parents were advised about the food and drugs to be avoided. [bloodjournal.org]

Neonatal jaundice Other names Neonatal hyperbilirubinemia, neonatal icterus, jaundice in newborns Jaundice in a newborn Specialty Pediatrics Symptoms Yellowish discoloration [en.wikipedia.org]