Nerve Conduction Velocity Decreased: Causes & Reasons

Possible Causes for Nerve Conduction Velocity Decreased

Nerve conduction velocities were decreased. Sural nerve biopsy showed inclusions typical of MLD. Arylsulfatase A was less than 5% of normal. [ncbi.nlm.nih.gov]

Serial neurophysiologic studies demonstrated a marked decrease of nerve conduction velocities, both motor and sensory, as well as prolongation or disappearance of brainstem [ncbi.nlm.nih.gov]

Diagnosis of metachromatic leukodystrophy is suggested clinically and by findings of decreased nerve conduction velocity; it is confirmed by DNA analysis and/or detecting [merckmanuals.com]

Charcot-Marie-Tooth Disease Type 4B3

Decreased nerve conduction velocity MedGen UID: 347509 •Concept ID: C1857640 • Finding A reduction in the speed at which electrical signals propagate along the axon of a neuron [ncbi.nlm.nih.gov]

nerve conduction velocity Distal sensory impairment Gait disturbance Intellectual disability Onion bulb formation Constitutional symptom Urinary incontinence [ncbi.nlm.nih.gov]

This finding affects peripheral nerves. [ncbi.nlm.nih.gov]

Xeroderma Pigmentosum Complementation Group B

Some XP-B patients present features of Cockayne syndrome, including cachectic dwarfism, pigmentary retinopathy, ataxia, decreased nerve conduction velocities. [uniprot.org]

nerve conduction velocities. [medical-dictionary.thefreedictionary.com]

Some XP-D patients have features of Cockayne syndrome, i.e., dwarfism, sensorineural deafness, microcephaly, mental retardation, pigmentary retinopathy, ataxia and decreased [medical-dictionary.thefreedictionary.com]

Fetal Akinesia - Cerebral and Retinal Hemorrhage Syndrome

nerve conduction velocity 32 HP:0000762 5 thin ribs 32 HP:0000883 6 polyhydramnios 32 HP:0001561 7 areflexia 32 HP:0001284 8 decreased fetal movement 32 HP:0001558 9 retinal [malacards.org]

Decreased nerve conduction velocity MedGen UID: 347509 • Concept ID: C1857640 • Finding A reduction in the speed at which electrical signals propagate along the axon of a [ncbi.nlm.nih.gov]

Some XP-G patients present features of Cockayne syndrome, cachectic dwarfism, pigmentary retinopathy, ataxia, decreased nerve conduction velocities. [molsoft.com]

Cockayne Syndrome

nerve conduction velocity, (4) sensorineural hearing loss, (5) sclerotic epiphyses, vertebral and pelvic abnormalities, thickening of the calvarium, (6) thin skin and brittle [accessanesthesiology.mhmedical.com]

[…] in size of the outer layer of the brain due to loss of brain cells 0002120 Decreased nerve conduction velocity 0000762 EEG abnormality 0002353 Erythema 0010783 Fine hair [rarediseases.info.nih.gov]

METHODS: Clinical and nerve conduction studies (NCS) in 25 CS patients with CSA (n=13) CSB (n=12) mutations. [ncbi.nlm.nih.gov]

Krabbe Disease

nerve conduction velocity 0000762 Developmental regression Loss of developmental milestones Mental deterioration in childhood [ more ] 0002376 Diffuse cerebral atrophy 0002506 [rarediseases.info.nih.gov]

[…] evoked potentials 0007928 Autoimmune thrombocytopenia 0001973 Autosomal recessive inheritance 0000007 Blindness 0000618 CNS demyelination 0007305 Decerebrate rigidity 0025013 Decreased [rarediseases.info.nih.gov]

Hereditary Areflexic Dystasia

[…] motor nerve conduction velocity ; Decreased number of peripheral myelinated nerve fibers ; Distal amyotrophy ; Distal muscle weakness ; Distal sensory impairment ; Gait ataxia [mousephenotype.org]

Nerve conduction velocities are decreased and sural nerve biopsy shows loss of myelinated fibers. [mendelian.co]

Nerve conduction studies (tests to assess nerve function) demonstrate decreased nerve conduction velocity (the nerves don't send nerve impulses as well as they should). [footdoc.ca]

Sphingolipid Activator Protein 1 Deficiency

Review Sphingolipid activator protein deficiency in a 16-week-old atypical Gaucher disease patient and his fetal sibling: biochemical signs of combined sphingolipidoses K Harzer et al. Eur J Pediatr. 1989 Oct. Abstract We describe a patient who presented shortly after birth with hyperkinetic behaviour, myoclonia,[…] [pubmed.ncbi.nlm.nih.gov]

Combined Oxidative Phosphorylation Defect Type 13

Completely updated, the new edition of this easy-to-reference text examines the physiological, biochemical, and genetic aspects of pediatric endocrine disorders. Leaders in the field discuss the hottest topics-including genetics, diabetes and obesity-impacting today s endocrine practice, keeping you up to date. A[…] [books.google.com]

Charcot-Marie-Tooth Disease Type 2A1

Decreased motor nerve conduction velocity MedGen UID: 388130 •Concept ID: C1858729 • Finding A type of decreased nerve conduction velocity that affects the motor neuron. [ncbi.nlm.nih.gov]

nerve conduction velocities (NCVs). [ncbi.nlm.nih.gov]

[…] motor nerve conduction velocity Decreased number of peripheral myelinated nerve fibers Distal sensory impairment Hyporeflexia Onion bulb formation Peripheral axonal atrophy [ncbi.nlm.nih.gov]

Charcot-Marie-Tooth Disease Type 4G

Decreased nerve conduction velocity Decreased NCV, Reduced nerve conduction velocities, Delayed nerve conduction velocity, Slow nerve conduction velocity, Slowed nerve conduction [rarediseases.oscar.ncsu.edu]

velocities, Decreased nerve conduction velocities [more] A reduction in the speed at which electrical signals propagate along the axon of a neuron. [rarediseases.oscar.ncsu.edu]

Charcot-Marie-Tooth Disease Type 2B1

[…] motor nerve conduction velocity Decreased number of peripheral myelinated nerve fibers Distal sensory impairment Onion bulb formation Peripheral axonal atrophy Steppage gait [ncbi.nlm.nih.gov]

Foot dorsiflexor weakness Kyphoscoliosis Proximal muscle weakness Upper limb muscle weakness Abnormality of the nervous system Areflexia Axonal degeneration/regeneration Decreased [ncbi.nlm.nih.gov]

Charcot-Marie-Tooth Disease Type 2B2

[…] motor nerve conduction velocity Distal sensory impairment IMPORTANT NOTE: NIH does not independently verify information submitted to the GTR; it relies on submitters to provide [ncbi.nlm.nih.gov]

Abnormality of the musculoskeletal system Distal amyotrophy Distal muscle weakness Abnormality of the nervous system Areflexia Decreased motor nerve conduction velocity Distal [ncbi.nlm.nih.gov]

Peripheral Demyelinating Neuropathy - Central Dysmyelination - Waardenburg Syndrome - Hirschsprung Disease

Charcot-Marie-Tooth Disease Type 4B2

[…] motor nerve conduction velocity Decreased number of peripheral myelinated nerve fibers Distal sensory impairment Hyporeflexia Onion bulb formation Segmental peripheral demyelination [ncbi.nlm.nih.gov]

velocities, Decreased nerve conduction velocities [more] A reduction in the speed at which electrical signals propagate along the axon of a neuron. [rarediseases.oscar.ncsu.edu]

Charcot-Marie-Tooth Disease Type 2T

[…] motor nerve conduction velocity 0003431 Distal amyotrophy Distal muscle wasting 0003693 Distal muscle weakness Weakness of outermost muscles 0002460 EMG: chronic denervation [rarediseases.info.nih.gov]

[…] signs 0003444 Hammertoe Hammer toe Hammertoes [ more ] 0001765 Hyporeflexia Decreased reflex response Decreased reflexes [ more ] 0001265 Impaired distal tactile sensation [rarediseases.info.nih.gov]

[…] symptoms is not available through HPO Areflexia Absent tendon reflexes 0001284 Autosomal dominant inheritance 0000006 Cardiomyopathy Disease of the heart muscle 0001638 Decreased [rarediseases.info.nih.gov]

Charcot-Marie-Tooth Disease Type 1F

[…] motor nerve conduction velocity Decreased number of peripheral myelinated nerve fibers Distal sensory impairment Global developmental delay Hyporeflexia Motor delay Myelin [ncbi.nlm.nih.gov]

CMT1 is the most common form of CMT and is characterized by abnormalities in nerve myelin that leads to decreased nerve conduction velocities. [rarediseases.org]

Dysphagia Abnormality of the musculoskeletal system Distal amyotrophy Distal muscle weakness Abnormality of the nervous system Areflexia Clusters of axonal regeneration Decreased [ncbi.nlm.nih.gov]

Charcot-Marie-Tooth Disease Type 4D

nerve conduction velocity Distal sensory impairment Gait disturbance Hyporeflexia Onion bulb formation Segmental peripheral demyelination/remyelination Ear malformation Hearing [ncbi.nlm.nih.gov]

Abnormality of the musculoskeletal system Distal amyotrophy Distal muscle weakness Abnormality of the nervous system Abnormal auditory evoked potentials Areflexia Axonal loss Decreased [ncbi.nlm.nih.gov]

Charcot-Marie-Tooth Disease Type 4J

[…] motor nerve conduction velocity Decreased nerve conduction velocity Distal sensory impairment Frequent falls Gait disturbance Motor delay Onion bulb formation Peripheral [ncbi.nlm.nih.gov]

Abnormality of the musculoskeletal system Ankle contracture Distal arthrogryposis Distal muscle weakness Frequent falls Abnormality of the nervous system Areflexia Axonal loss Decreased [ncbi.nlm.nih.gov]

Charcot-Marie-Tooth Disease Type 4H

[…] motor nerve conduction velocity Decreased number of peripheral myelinated nerve fibers Distal sensory impairment Hypoesthesia Hyporeflexia Motor delay Onion bulb formation [ncbi.nlm.nih.gov]

(in general, this finding can be observed on nerve biopsy). [ncbi.nlm.nih.gov]

Dominant Intermediate Charcot-Marie-Tooth Disease Type E

Congenital Hypomyelinating Neuropathy

Electromyography generally reveals decreased nerve conduction velocity. [anestesiarianimazione.com]

INTRODUCTION Hereditary motor-sensory neuropathies are abnormalities of axons or Schwann cells and their myelin sheaths, with peripheral nerve dysfunction. [anestesiarianimazione.com]

Charcot-Marie-Tooth Disease Type 2N

[…] motor nerve conduction velocity 0003431 Decreased number of peripheral myelinated nerve fibers 0003380 Distal amyotrophy Distal muscle wasting 0003693 Dystrophic toenail [rarediseases.info.nih.gov]

[…] available through HPO Areflexia Absent tendon reflexes 0001284 Autoamputation of foot 0001868 Autosomal dominant inheritance 0000006 Axonal degeneration/regeneration 0003378 Decreased [rarediseases.info.nih.gov]

Charcot-Marie-Tooth Disease Type 4A

[…] motor nerve conduction velocity Decreased number of peripheral myelinated nerve fibers Decreased sensory nerve conduction velocity Distal sensory impairment Hypertrophic [ncbi.nlm.nih.gov]

Motor nerve conduction velocities are decreased, and sural nerve biopsies show loss of myelinated fibers. [ncbi.nlm.nih.gov]

Charcot-Marie-Tooth Disease Type 1D

CMT1 is the most common form of CMT and is characterized by abnormalities in nerve myelin that leads to decreased nerve conduction velocities. [rarediseases.org]

[…] motor nerve conduction velocity Decreased number of peripheral myelinated nerve fibers Distal sensory impairment Hypertrophic nerve changes Hyporeflexia Myelin outfoldings [ncbi.nlm.nih.gov]

Diphtheritic Neuropathy

Nerve conduction studies show decreased conduction velocity. [tratamientoneuropatia.com]

The two key laboratory abnormalities in GBS are decreased nerve conduction velocity or conduction block and elevated CSF protein with relatively few cells (albuminocytologic [peripheralneuropathytreatments.com]

Nerve conduction studies show decreased conduction velocity, conduction block, and prolonged distal latencies and F waves. [tratamientoneuropatia.com]

Charcot-Marie-Tooth Disease Type 1C

This finding affects peripheral nerves. [ncbi.nlm.nih.gov]

Charcot-Marie-Tooth Disease Type 4C

[…] reduction is not directly proportional to the disease duration.3 The decrease in the motor nerve conduction velocity in both the upper and lower extremities at 11 ms to 18 [neupsykey.com]

Axonal degeneration Basal lamina 'onion bulb' formation Decreased motor nerve conduction velocity Decreased number of large peripheral myelinated nerve fibers Difficulty [ncbi.nlm.nih.gov]

Yuan-Harel-Lupski Syndrome

Poor speech MedGen UID: 341172 •Concept ID: C1848207 • Finding Decreased nerve conduction velocity MedGen UID: 347509 •Concept ID: C1857640 • Finding A reduction in the speed [ncbi.nlm.nih.gov]

Electrophysiologic studies, performed in only some patients, showed decreased nerve conduction velocities. [findzebra.com]

nerve conduction velocity Delayed ability to walk Demyelinating peripheral neuropathy Distal sensory impairment Gait ataxia Global developmental delay Intellectual disability [ncbi.nlm.nih.gov]

Déjerine-Sottas Disease

Nerve conduction velocities are severely decreased (sometimes less than 10 m/s), and sural nerve biopsy shows severe loss of myelinated fibers (summary by Baets et al., 2011 [ncbi.nlm.nih.gov]

Nerve conduction studies (tests to assess nerve function) demonstrate decreased nerve conduction velocity (the nerves don't send nerve impulses as well as they should). [footdoc.ca]

Electromyography generally reveals decreased nerve conduction velocity. [scielo.br]