Hallervorden-Spatz Syndrome
(disorder) Pigmentary pallidal degeneration Neurodegeneration With Brain Iron Accumulation type 1 Pantothenate Kinase-Associated Neurodegeneration NEURODEGENERATION WITH[wikidata.org]
neurodegeneration; PKAN pantothenate kinase-associated neurodegeneration; XL X-linked 1.[ncbi.nlm.nih.gov]
BRAIN IRON ACCUMULATION 1; NBIA1 PKAN Pkan Neuroaxonal Dystrophy, Juvenile-Onset edit English pantothenate kinase-associated neurodegeneration A neurodegeneration with brain[wikidata.org]
Wolfram Syndrome
This work is necessary to position the field for future clinical trials to test interventions for WFS neurodegeneration.[clinicaltrials.gov]
In patients with Wolfram syndrome, these mechanisms underlie progressive neurodegeneration and endocrine dysfunction.[care.diabetesjournals.org]
Ultimately, a better understanding of the trajectory of neurodegeneration in WFS and the development of effective interventions may be relevant to other more common neurodegenerative[clinicaltrials.gov]
Alzheimer Disease
Serum NfL may thus be a feasible biomarker of early AD-related neurodegeneration. Copyright 2017 The Author(s).[ncbi.nlm.nih.gov]
Furthermore, in DLB, Aβ 1–42 may promote α-synuclein accumulation and neurodegeneration.[doi.org]
A. (2003) Alpha-synuclein overexpression protects against paraquat-induced neurodegeneration. J. Neurosci. 23, 3095–3099.[doi.org]
Spinocerebellar Ataxia Type 1
The objective of this study is to evaluate neurochemical changes associated with neurodegeneration in cerebral tissue in SCA1 patients compared to age- and gender-matched[ncbi.nlm.nih.gov]
Keywords Neurodegeneration Polyglutamine Therapeutic approaches References 1.[doi.org]
These data demonstrate that presymptomatic and progressive neurodegeneration in SCA1 can be noninvasively monitored using MRS.[ncbi.nlm.nih.gov]
Neurodegenerative Disorder
In addition, it is the progressive neurodegeneration which determines the amount of accumulating clinical disability.[ncbi.nlm.nih.gov]
[…] and Repair: The interdepartmental program in Cellular Neuroscience, Neurodegeneration and Repair (CNNR) will accelerate the pace of Yale's research on neurodegeneration diseases[medicine.yale.edu]
All of these conditions lead to progressive brain damage and neurodegeneration.[news-medical.net]
Parkinson's Disease
In this review, we address the current concept of neuroinflammation and its involvement in PD-associated neurodegeneration.[ncbi.nlm.nih.gov]
However, 5-10% of PD cases are inherited as monogenic diseases, which provides a chance to understand the molecular mechanisms underlying neurodegeneration.[ncbi.nlm.nih.gov]
Open Access Review 1 Department of Biological Sciences, The University of Alabama, Tuscaloosa, AL 35487, USA 2 Departments of Neurology and Neurobiology, Center for Neurodegeneration[doi.org]
Lafora Disease
These animals did not show the increase in markers of neurodegeneration, the impairments in electrophysiological properties of hippocampal synapses, nor the susceptibility[ncbi.nlm.nih.gov]
Lafora disease is a metabolic disorder resulting in accumulation of water-insoluble glucan in the cytoplasm, and manifests as a debilitating neurodegeneration that ends with[ncbi.nlm.nih.gov]
Our results emphasize the relevance of the laforin-malin complex in the control of glycogen metabolism and highlight altered glycogen accumulation as a key contributor to neurodegeneration[ncbi.nlm.nih.gov]
REM Sleep Behavior Disorder
So far, the number of studies assessing predictive markers of neurodegeneration in RBD is limited.[n.neurology.org]
[…] treatment consequences of RBD in the context of neurodegeneration. 2018 S. Karger AG, Basel.[ncbi.nlm.nih.gov]
"Rapid-eye movement sleep behavior disorder is not just a precursor but also a critical warning sign of neurodegeneration that can lead to brain disease," John Peever, associate[universityherald.com]
Neurodegeneration with Brain Iron Accumulation
In addition to pantothenate kinase-associated neurodegeneration (PKAN) and phospholipase A2-associated neurodegeneration (PLAN), fatty acid hydroxylase-associated neurodegeneration[ncbi.nlm.nih.gov]
[…] acid hydroxylase-associated neurodegeneration, respectively).[ncbi.nlm.nih.gov]
"Neurodegeneration with Brain Iron Accumulation Information Page". National Institute of Neurological Disorders and Stroke.[en.wikipedia.org]
Beta-Propeller Protein-Associated Neurodegeneration
Neurodegeneration with brain iron accumulation (NBIA) is a heterogeneous group of inherited neurologic disorders with iron accumulation in the basal ganglia, which share magnetic[ncbi.nlm.nih.gov]
Beta-propeller protein-associated neurodegeneration is a newly described X-linked dominant condition due to heterozygous mutations in WDR45.[ncbi.nlm.nih.gov]
Static encephalopathy of childhood with neurodegeneration in adulthood is a phenotypically distinctive, X-linked dominant subtype of neurodegeneration with brain iron accumulation[ncbi.nlm.nih.gov]