Alzheimer Disease
To determine the relation of neuritic plaques (NPs) and neurofibrillary tangles (NFTs) to the development and evolution of Alzheimer disease (AD).[ncbi.nlm.nih.gov]
The observation of Lewy bodies in familial AD cases suggests that like neurofibrillary tangles, the formation of Lewy bodies can be induced by the pathological state caused[ncbi.nlm.nih.gov]
Neurofibrillary tangles and beta-amyloid plaques have been observed in the amygdala in Alzheimer disease.[ncbi.nlm.nih.gov]
Progressive Supranuclear Palsy
Its pathology reveals that Alzheimer's neurofibrillary tangles (NFTs) are situated especially in the nuclei of basal ganglia and brainstem.[ncbi.nlm.nih.gov]
PSP is defined neuropathologically by the accumulation of neurofibrillary tangles in the subthalamic nucleus, pallidum, red nucleus, substantia nigra, striatum, pontine tegmentum[ncbi.nlm.nih.gov]
Alzheimer's disease pathology was advanced with PSP-like neurofibrillary tangles distribution, and Lewy bodies were abundant in limbic lobe, while scarce in lower brainstem[ncbi.nlm.nih.gov]
Classic Progressive Supranuclear Palsy Syndrome
tangles and neuropil threads to a lesser extent.[33, 39] Much like Alzheimer disease, PSP is characterized by neurofibrillary tangles causing nerve cell loss, gliosis, and[eyewiki.aao.org]
Pathological examination disclosed histopathological features of PSP, including argyrophilic and tau-positive tufted astrocytes, neurofibrillary tangles, coiled bodies, and[okayama.pure.elsevier.com]
The neurofibrillary tangles deposited in PSP can be distinguished from those seen in Alzheimer's disease in a number of ways.[pmj.bmj.com]
Early-Onset Autosomal Dominant Alzheimer Disease
These mutations result in an incompletely understood cascade of events resulting in neuronal death, synapse loss, and the formation of neurofibrillary tangles and senile plaques[orpha.net]
tangles.[disabled-world.com]
A post-mortem diagnosis can be achieved through an examination that reveals intraneuronal neurofibrillary tangles and beta-amyloid neuritic plaques.[disabled-world.com]
Boxer's Dementia
Dale GE, Leigh PN, Luthert P, Anderton BH, Roberts GW (1991) Neurofibrillary tangles in dementia pugilistica are ubiquitinated.[link.springer.com]
Neurofibrillary tangles have been found in the brains of dementia pugilistica patients, but not in the same distribution as is usually found in people with Alzheimer's.[diki.pl]
Differential distribution of neurofibrillary tangles in the cerebral cortex of dementia pugilistica and Alzheimer's disease cases.[doi.org]
Posterior Cortical Atrophy
Determining the relative contribution of amyloid plaques and neurofibrillary tangles to brain dysfunction in Alzheimer disease is critical for therapeutic approaches, but[ncbi.nlm.nih.gov]
Posterior cortical atrophy is a dementia syndrome with symptoms of cortical visual dysfunction, associated with amyloid plaques and neurofibrillary tangles predominantly affecting[ncbi.nlm.nih.gov]
Both cases displayed very high densities of neurofibrillary tangles and senile plaques in the primary visual cortex, secondary visual cortex, visual association areas of the[ncbi.nlm.nih.gov]
Hallervorden-Spatz Syndrome
Numerous neurofibrillary tangles (NFTs) were found within the hippocampal cortex, neocortex and brain stem.[ncbi.nlm.nih.gov]
tangles due to hyperphosphorilated tau aggregation.[ncbi.nlm.nih.gov]
In addition, there was diffuse sponginess in the atrophic cortex as well as widespread Alzheimer's neurofibrillary tangles (NFTs) and Lewy bodies (LBs) in the cortical and[ncbi.nlm.nih.gov]
ADan Amyloidosis
These findings support the notion that parenchymal amyloid fibril formation is not a prerequisite for the development of neurofibrillary tangles.[indiana.pure.elsevier.com]
tangles.[ri.conicet.gov.ar]
FDD is a novel form of CNS amyloidosis with extensive neurofibrillary degeneration occurring with parenchymal, predominantly pre-amyloid rather than amyloid, deposition.[indiana.pure.elsevier.com]
Cerebral Cortical Atrophy
الصفحة 506 - GW, 1991, The topographical and neuroanatomical distribution of neurofibrillary tangles and neuritic plaques in the cerebral cortex of patients with Alzheimer's[books.google.com]
Significantly higher neurofibrillary tangle and senile plaque densities were found in the more atrophic side in most of the areas studied.[link.springer.com]
In many people with posterior cortical atrophy, the affected part of the brain shows amyloid plaques and neurofibrillary tangles, similar to the changes that occur in Alzheimer[alz.org]
Dementia with Lewy Bodies
tangle burden.[ncbi.nlm.nih.gov]
Neurofibrillary tangles (NFT) were almost restricted to the entorhinal cortex, while senile plaques were absent.[ncbi.nlm.nih.gov]
The association between ante mortem [(11)C]-Pittsburgh Compound B (PiB) retention and β-amyloid (Aβ) load, Lewy body (LB) and neurofibrillary tangle (NFT) densities were investigated[ncbi.nlm.nih.gov]