Neurologic-involvement: Causes & Reasons

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Possible Causes for neurologic involvement

Gaucher Disease

We report a case of recurrent cholelithiasis and liver failure in a patient with type 2 Gaucher disease who showed severe progressive neurological involvement. [ncbi.nlm.nih.gov]

Type A is a lethal infantile form with marked progressive neurologic involvement. [accessmedicine.mhmedical.com]

Three distinct GD subtypes have been described with varying clinical features based on the presence or absence of neurologic involvement. [ncbi.nlm.nih.gov]

Gaucher Disease Type 2

These types are determined by the absence or presence and severity of neurological involvement. [themedicalbiochemistrypage.org]

lungs and kidneys may also be involved, but the CNS is spared type II (acute neuropathic form or infantile form): severe progressive neurological involvement with death [radiopaedia.org]

Type 3 Gaucher disease also has neurological involvement but not as severe as Type 2 Gaucher. [huffingtonpost.co.uk]

Niemann-Pick Disease Type B

Survival into adulthood and absence of gross neurological involvement suggests Niemann-Pick disease type B. [ncbi.nlm.nih.gov]

NPD type B is a rare inborn error of metabolism, with a benign course and prognosis, while types A and C are always associated with severe neurological involvement. [ncbi.nlm.nih.gov]

It appears that the lack of neurological involvement in type B patients cannot be due to an obvious presence of significant lysosomal sphingomyelinase activity in brain. [ncbi.nlm.nih.gov]

Niemann-Pick Disease

Type B Niemann-Pick disease is a less severe form with milder neurological involvement, characterized by hepatosplenomegaly, hyperlipidemia, and pulmonary involvement; most [ncbi.nlm.nih.gov]

Survival into adulthood and absence of gross neurological involvement suggests Niemann-Pick disease type B. [ncbi.nlm.nih.gov]

This non-fatal missense mutation leads to –20% residual lysosomal acid sphingomyelinase activity in vitro and only results in hepatosplenomegaly without neurologic involvement [ncbi.nlm.nih.gov]

Behçet Disease

Neurological manifestations are present in 5-10%, and gastrointestinal tract involvement in 10-15% of cases. [ncbi.nlm.nih.gov]

It is not known whether this is the consequence of mucosal involvement or neurologic involvement. [ncbi.nlm.nih.gov]

Our study included 14 individuals with BD with neurological involvement (neuroBehçet syndrome - NBS), 16 individuals with BD without neurological involvement and 18 healthy [ncbi.nlm.nih.gov]

Vitamin B12 Deficiency

There are inadequate data at the present time to support the use of oral cyanocobalamin replacement in patients with severe neurologic involvement. [ncbi.nlm.nih.gov]

involvement. [bloodjournal.org]

Standard initial treatment for patients without neurological involvement is 1000 µg intramuscularly three times a week for two weeks. [doi.org]

Common Cold

Signs of increased intracranial pressure (eg, papilledema, altered mental status, neurologic findings) may suggest intracranial involvement. [emedicine.com]

Acute Sarcoidosis

Given the wide a range of neurologic involvement, patients may present with virtually any neurologic complaint. [emedicine.medscape.com]

[…] findings Neurologic manifestations include cranial nerve VII involvement (unilaterally or bilaterally), Bell palsy, basal granulomatous meningitis (ie, aseptic meningitis [emedicine.medscape.com]

Systemic immunosuppressive agents are indicated in patients who are dependent on or intolerant of corticosteroids. [4] Neurologic care Patients who have CNS involvement may [emedicine.medscape.com]

Spondyloenchondrodysplasia

Manifestation of the disorder may include neurological involvement (spasticity, intracranial calcifications and mental retardation) and immune dysfunction. [ncbi.nlm.nih.gov]

The clinical spectrum of SPENCD includes neurological involvement and immune dysfunction, such as systemic lupus erythematosus (SLE). [ncbi.nlm.nih.gov]

[…] or immunologic involvement. [ncbi.nlm.nih.gov]

Viral Lower Respiratory Infection

Outbreak of enterovirus 71 infection in Victoria, Australia, with a high incidence of neurologic involvement. Pediatr. Infect. Dis. J. 7 : 484 – 488. 54. Glezen, W. [asmscience.org]

Signs of increased intracranial pressure (eg, papilledema, altered mental status, neurologic findings) may suggest intracranial involvement. [emedicine.medscape.com]

Urinary Tract Disease

Urinary surgery or an exam of your urinary tract that involves medical instruments can both increase your risk of developing a urinary tract infection. [mayoclinic.org]

Uncomplicated UTI involves the urinary bladder in a host without underlying renal, metabolic, or neurologic diseases. [emedicine.medscape.com]

This may include people who are hospitalized, people with neurological problems that make it difficult to control their ability to urinate and people who are paralyzed. [mayoclinic.org]

Transcobalamin 2 Deficiency

A case of hereditary transcobalamin II deficiency with neurological involvement is described. [ncbi.nlm.nih.gov]

Neurological involvement in hereditary transcobalamin II deficiency. [jnnp.bmj.com]

Thomas PD, Hoffbrand AV, Smith IS (1982) Neurologic involvement in hereditary transcobalamin II deficiency. [link.springer.com]

Mucopolysaccharidosis Type 2

In patients with neurologic involvement, intelligence is impaired, and death usually occurs in the second decade of life, whereas those patients with minimal or no neurologic [pediatrics.aappublications.org]

involvement. [pediatrics.aappublications.org]

involvement may survive into adulthood with normal intellectual development. [pediatrics.aappublications.org]

Viral Upper Respiratory Tract Infection

Signs of increased intracranial pressure (eg, papilledema, altered mental status, neurologic findings) may suggest intracranial involvement. [emedicine.medscape.com]

[…] the bony areas adjacent to sinuses Peri-orbital involvement Visual or neurological disturbance Beta Lactam allergy 2, 3, 6 Pneumonia Relevant Co morbidities Immunocompromised [slideshare.net]

[…] or splenomegaly Asymmetrical pharyngeal swelling Peri-tonsillar abscess Epiglotitis Signs of meningitis Age 70 years Inability to swallow / dehydration Torticollis Oedema involving [slideshare.net]

Upper Respiratory Infection

Signs of increased intracranial pressure (eg, papilledema, altered mental status, neurologic findings) may suggest intracranial involvement. [emedicine.medscape.com]

Neurologic Manifestation of Whipple Disease

Although previously considered a late manifestation of Whipple disease, neurological involvement is now frequently the initial clinical manifestation and represents the greatest [ncbi.nlm.nih.gov]

It has been suggested that neurological involvement will eventually occur in all patients with Whipple disease. [radiopaedia.org]

[…] of intestinal involvement, and neurologic relapse of previously treated WD. [asmscience.org]

Vitamin D Deficiency

Dementia involves a decline in thinking, behavior, and memory that negatively affects daily life. [everydayhealth.com]

Dementia and Vitamin D Deficiency A study published in August 2014 in the journal Neurology found that moderate and severe vitamin D deficiency in older adults was associated [everydayhealth.com]

Omsk Hemorrhagic Fever

involvement. [en.wikipedia.org]

[…] uterus, and lungs, a papulovesicular rash on the soft palate, cervical lymphadenopathy (it occurs in the neck which that enlarges the lymph glandular tissue), and occasional neurological [en.wikipedia.org]

Acute Alcohol Intoxication

Clinical manifestations are heterogeneous and involve different organs and apparatuses, with behavioral, cardiac, gastrointestinal, pulmonary, neurological, and metabolic [ncbi.nlm.nih.gov]

While swallowing dysfunction is associated with aspiration pneumonia, dysphagia may not be sufficient unless other risk factors are present.[3] Neurologic conditions that [en.wikipedia.org]

[…] can directly impact the nerves involved in the swallow mechanism include stroke, Parkinson's disease, and multiple sclerosis.[1] Anatomical changes in the chest can also disrupt [en.wikipedia.org]

Farber Disease

Evaluation of neurological involvement is difficult as movement causes extreme pain in afflicted infants. [themedicalbiochemistrypage.org]

However, allogeneic hematopoietic stem cell transplantation provides a promising approach for patients with limited neurological involvement. [orpha.net]

In addition the neurologic involvement is much more mild than in type 1. Type 4 is referred to as the "neonatal-visceral" form of the disease. [themedicalbiochemistrypage.org]

Sea-blue histiocytosis

It is characterized by childhood onset of hepatosplenomegaly, lack of neurological involvement and diminished sphingomyelinase activity. [ncbi.nlm.nih.gov]

It seems clear that chronic Niemann-Pick disease without neurological involvement is associated with sea blue histiocytosis. [ncbi.nlm.nih.gov]

NPD type B is a rare inborn error of metabolism, with a benign course and prognosis, while types A and C are always associated with severe neurological involvement. [ncbi.nlm.nih.gov]

Urinary Tract Infection

Uncomplicated UTI involves the urinary bladder in a host without underlying renal, metabolic, or neurologic diseases. [emedicine.medscape.com]

Urinary surgery or an exam of your urinary tract that involves medical instruments can both increase your risk of developing a urinary tract infection. [mayoclinic.org]

This may include people who are hospitalized, people with neurological problems that make it difficult to control their ability to urinate and people who are paralyzed. [mayoclinic.org]

Hemolytic Uremic Syndrome

Neurologic involvement is the most threatening complication of diarrhea-associated hemolytic uremic syndrome (D HUS). [ncbi.nlm.nih.gov]

Severe neurologic involvement is not rare in D HUS. [doi.org]

Neurologic involvement is frequent but often reversible. [ncbi.nlm.nih.gov]

Eales Disease

Eales disease is a disease of unknown aetiology characterised by ophthalmic changes and often neurological involvement as in multiple sclerosis. [ncbi.nlm.nih.gov]

Vaginal Candidiasis

Any child who is suspected of having congenital syphilis or who has neurologic involvement should be treated with aqueous penicillin G. [web.archive.org]

Therefore, unless clinical signs or symptoms of neurologic or ophthalmic involvement are present, CSF analysis is not recommended for routine evaluation of patients who have [web.archive.org]

A patient who has clinical evidence of neurologic involvement with syphilis (e.g., cognitive dysfunction, motor or sensory deficits, ophthalmic or auditory symptoms, cranial [web.archive.org]

Insect Bite

Treatment of West Nile virus is supportive involving monitoring, fluid replacement, analgesics and rest. [podiatrytoday.com]

Rarely, infected individuals develop neurologic disease, which can present as meningitis, encephalitis or paralysis. [podiatrytoday.com]

Cystitis

Uncomplicated UTI involves the urinary bladder in a host without underlying renal, metabolic, or neurologic diseases. [emedicine.medscape.com]

Often cystitis is not an isolated infection but is a result of some other physical condition, such as urinary retention, calculi in the bladder, tumors, or neurologic diseases [medical-dictionary.thefreedictionary.com]

Many patients present with pain symptoms suggesting involvement of multiple organ systems. [auanet.org]

Transient Sarcoidosis

Over time, skin, eye, and neurologic involvement seem more apparent. [what-when-how.com]

Neurosarcoidosis generally occurs only in cases of sarcoidosis with substantial systemic involvement, and signs of neurologic involvement usually are seen in patients known [emedicine.medscape.com]

Bell's palsy and lymphocytic meningitis are common manifestations of neurological involvement but diabetes insipidus is also seen. [patient.info]

Constipation

Neuroimaging shows cerebral edema of different patterns, classically involving the parieto-occipital white matter. [ncbi.nlm.nih.gov]

To compare alternative management strategies for faecal incontinence and constipation in people with neurological diseases involving the central nervous system. [dx.doi.org]

[…] encephalopathy syndrome (PRES) is a clinico-radiological entity characterized by variable associations of headaches, encephalopathy, seizures, vomiting, visual disturbance, and focal neurological [ncbi.nlm.nih.gov]

Acute Cystitis

Uncomplicated UTI involves the urinary bladder in a host without underlying renal, metabolic, or neurologic diseases. [emedicine.com]