Patients with MPS1S may have little or no neurological involvement, normal stature and life span, but present development of joints stiffness, mild hepatosplenomegaly, aortic
[uniprot.org]
Thus, brain and spinal MR imaging are valuable tools for the assessment of neurologic involvement, and there is evidence that they might be reliable markers demonstrating
[ajnr.org]
involvement. [1], [2] All these syndromes are autosomal recessive, with the exception of the X-linked recessive Hunter syndrome.
[jcor.in]