Possible Causes for neurologic manifestation Stroke Other manifestations, rather than neurologic deficits, often suggest the type of stroke. For example, Sudden, severe headache suggests subarachnoid hemorrhage. [msdmanuals.com] While spasms of this muscle constitute the hallmark of disease, other motor manifestations include increased spontaneous blinking and apraxia of eyelid opening. [ncbi.nlm.nih.gov] Less commonly, HBOT may be associated with acute neurological toxicity manifesting as seizure. [doi.org] Primary Progressive Multiple Sclerosis Neurofibromatosis 1 (NF1) is a common autosomal disorder with a wide range of neurological manifestations. [ncbi.nlm.nih.gov] Abstract Primary progressive multiple sclerosis (PP-MS) is a less common progressive form of MS in approximately 10% of patients that manifest increasingly neurological disability [ncbi.nlm.nih.gov] Author information 1 Department of Neurology, Tokushima Hospital, National Hospital Organization, Tokushima, Japan. Electronic address: inuito@tokusima.hosp.go.jp. [ncbi.nlm.nih.gov] Rolandic Epilepsy Helen Cross, Gerhard Kluger and Lieven Lagae, Advancing the management of childhood epilepsies, European Journal of Paediatric Neurology, 17, 4, (334), (2013). [doi.org] Kothare, Electrical Status Epilepticus in Sleep: Clinical Presentation and Pathophysiology, Pediatric Neurology, 47, 6, (390), (2012). [doi.org] Ferreira, Origin and dynamics of epileptic activity in a symptomatic case of Panayiotopoulos syndrome: Correlation with clinical manifestations, Clinical Neurophysiology, [doi.org] Guillain-Barré Syndrome Guillain-Barré syndrome (GBS), transverse myelitis, meningoencephalitis, ophthalmological manifestations, and other neurological complications have been recently associated [ncbi.nlm.nih.gov] The time between ZIKV acute symptoms and the development of neurological manifestations varied from 3 to 13 days and ZIKV was detected between 15 and 34 days after the initial [ncbi.nlm.nih.gov] Abstract Various forms of neurological manifestations are reported in dengue fever. [ncbi.nlm.nih.gov] Multiple Sclerosis Our case adds to previous reports in this field and calls for awareness of this exceptional extra-neurological manifestation of MS. [ncbi.nlm.nih.gov] Particular attention has focused on the hypothesis that cryptic gluten sensitivity may play a role in the neurological manifestations of MS ( Ghezzi 2001 ). [dx.doi.org] Vitamin B Deficiency Median duration to onset of neurologic manifestation following surgery was 12 months (IQR, 5-32). [ncbi.nlm.nih.gov] Vitamin B 12 deficiency is associated with various symptoms, of which the haematological and neurological manifestations are the most prominent. [nature.com] The neurological manifestations include myelopathy (disease of the spinal cord), neuropathy (disease of the nerves), sensory disturbances, gait abnormalities, and weakness [brainblogger.com] Vitamin B12 Deficiency manifestations. [ncbi.nlm.nih.gov] Vitamin B12 (B12) deficiency is known to be associated with various neurological manifestations. [ncbi.nlm.nih.gov] Patients with vitamin B12 deficiency have protean neurological manifestations that are often insidious. [ncbi.nlm.nih.gov] Variegate Porphyria Though variegate prophyria with neurologic manifestations is not uncommon syringomyelic type of sensory loss is most unusual. [ncbi.nlm.nih.gov] manifestations. [ncbi.nlm.nih.gov] It is characterized by cutaneous photosensitivity and/or various neurological manifestations. [ncbi.nlm.nih.gov] Cerebral Thrombotic Thrombocytopenic Purpura manifestations of stroke disorder. [books.google.it] It is estimated that 50% of patients with TTP present with neurologic manifestations that include seizures and fluctuating neurologic deficits from small vessel infarctions [shmabstracts.com] manifestations of stroke * A guide to highly studied topics, including stroke complications, syndromes, and stroke related psychiatric disorders * A better understanding [books.google.it] Rett Syndrome Neuroimaging may be used to exclude other causes of the neurological manifestations. [patient.info] (from menkes, textbook of child neurology, 5th ed, p199) Progressive disorder affecting the cerebral cortex of females; present from birth; manifested by autistic behavior [icd10data.com] Wilson Disease Manifestations are primarily hepatic and/or neuropsychiatric, with a variety of neurological phenotypes. [ncbi.nlm.nih.gov] Although liver transplant for decompensated cirrhosis secondary to Wilson disease is well accepted, the use of transplant for patients with severe neurologic manifestations [ncbi.nlm.nih.gov] METHODS: 34 WD patients with neurological manifestation with a median age of 14 years were included. [ncbi.nlm.nih.gov] Dementia with Lewy Bodies LBD is a degenerative neurological disease manifested by cognitive impairment, variable Parkinsonism, and marked psychosis exhibiting both auditory and visual hallucinations [pmj.bmj.com] Psychotic symptoms and cognitive fluctuation are common manifestations of dementia with Lewy bodies (DLB). [ncbi.nlm.nih.gov] Prodromal clinical manifestations of neuropathologically confirmed Lewy body disease. Neurobiology of Aging 31, 1805 – 1813. [doi.org] Syndrome of Inappropriate Antidiuretic Hormone Secretion Neurologic manifestations Neurologic complications in SIADH occur as a result of the brain's response to changes in osmolality. [emedicine.medscape.com] Machado-Joseph Disease Machado-Joseph disease is a form of progressive spino-cerebellar ataxia with both bulbar and peripheral neurological manifestations. [ncbi.nlm.nih.gov] Manifestations Genetic Diseases, Inborn [clinicaltrials.gov] It has extensive polymorphic features, described through a spectrum of neurological, and especially, ophthalmological manifestations. [ncbi.nlm.nih.gov] Uveomeningoencephalitic Syndrome manifestations can include cerebral ischemia in the adult and pediatric population. [medlink.com] Patients must have either the neurologic manifestations or dermatological signs. c. [rarediseases.org] manifestation, 054078, 症状, ｼｮｳｼﾞｮｳ, symptom, 040039 [togodb.biosciencedbc.jp] Erythropoietic Coproporphyria In the few reported cases, clinical manifestations were primarily neurologic, without cutaneous photosensitivity. [ommbid.mhmedical.com] (b) Porphyria variegata: (i) Increased excretion of porphobilinogen in the urine during acute neurological manifestations and turns to normal in remission. [biologydiscussion.com] manifestation and is the most common type or form (estimated incidence of 1:10000 or 2-5:1000000 in the United Kingdom). [medcraveonline.com] Ataxia Telangiectasia Ataxia telangiectasia is a rare genetic disease characterized by neurological manifestations, infections, and cancers. [ncbi.nlm.nih.gov] Not infrequently, other neurological manifestations can be present. [statpearls.com] This is the first large-scale clinical trial of any drug to treat the neurologic manifestations of AT. [innogest.it] Crigler-Najjar Syndrome Type 1 Before the age of 15, the patient did not manifest any neurological or behavioural dysfunction despite increased bilirubin in serum. [ncbi.nlm.nih.gov] Bilirubin encephalopathy (kernicterus manifesting as hypotonia, deafness, oculomotor palsy and lethargy) due to hyperbilirubinemia is a permanent risk. [orpha.net] Clinical description First clinical manifestations usually appear soon after birth. [orpha.net] Thalassemia Hemoglobin. 2016;40(2):127-9. doi: 10.3109/03630269.2015.1136935. Epub 2016 Feb 6. Abstract A female proband homozygous for both Hb Luton [α89(FG1)His Leu (CAC CTC), HBA2: c.269A T (or HBA1)], a high oxygen affinity hemoglobin (Hb), and for α( )-thalassemia (α-thal), (-α(4.2), leftward deletion) was first described in[…] [ncbi.nlm.nih.gov] Krabbe Disease Type 2 (acute neuronopathic) GD patients have hepatosplenomegaly similar to type 1, but develop also neurological manifestations (stridor, strabismus and other oculomotor [neuropathology-web.org] In recent years there have been reports of neurological variants, where age of onset and manifestations differed from the classical form. [ncbi.nlm.nih.gov] Clinical manifestations are exclusively neurologic with prominent white-matter signs. [ncbi.nlm.nih.gov] Kawasaki Disease PubMed Abstract Steinlin M, Blaser S, Gilday D: Neurological manifestations of paediatric systemic lupus erythematous. Pediatric Neurology 1995, 13 : 191-7. [web.archive.org] View Article PubMed Google Scholar Steinlin M, Blaser S, Gilday D: Neurological manifestations of paediatric systemic lupus erythematous. [doi.org] Pediatric Neurology. 1995, 13: 191-7. 10.1016/0887-8994(95)00110-2. [doi.org] Hereditary Areflexic Dystasia “R” — Roussy-Lévy syndrome to Rytand-Lipsitch syndrome Page 13 of 13 Roussy-Lévy syndrome - G60.0 Rubella (German measles) - B06.9 complication NEC - B06.09 neurological - [icd10coded.com] B06.00 congenital - P35.0 contact - Z20.4 exposure to - Z20.4 maternal manifest rubella in infant - P35.0 care for damage to fetus (suspected) - O35.3 suspected damage to [icd10coded.com] Diffuse Cerebral Sclerosis of Schilder manifestations. 15 Due to the adverse effects of Lorenzos oil, including thrombocytopenia and elevated liver enzymes, its use requires a careful laboratory monitoring. [scielo.mec.pt] manifestations. [doi.org] Although the variation in clinical phenotypes is great, neurologic manifestations are present in nearly all males by adulthood. [ncbi.nlm.nih.gov] Progressive Multifocal Leukoencephalopathy The rapid onset of his neurologic manifestations and the initial neuroimaging studies suggested acute disseminated encephalomyelitis (ADEM), and a brain biopsy was needed [pediatrics.aappublications.org] Neuro-ophthalmological disorders in HIV infected subjects with neurological manifestations 2004;88: 1455-1459. Tan CS, Koralnik IJ. [eyewiki.aao.org] Neurological manifestations of human immunodeficiency virus infection in adults. Neurology in Clinical Practice. 2004. 2: 1581-1602. [emedicine.com] Dentatorubral-Pallidoluysian Atrophy Dentatorubral-pallidoluysian atrophy (DRPLA) is an autosomal dominant spinocerebellar degeneration that exhibits a variety of neurologic manifestations. [ncbi.nlm.nih.gov] Background Dentatorubral-pallidoluysian atrophy (DRPLA) is an autosomal dominant spinocerebellar degeneration that exhibits a variety of neurologic manifestations. [doi.org] […] phenotype the observable actions or reactions of mammalian organisms that are manifested through development and lifespan Atn1 MGI:104725 MP:0005378 growth/size/body region [159.226.67.237] T-Cell Lymphoblastic Lymphoma Exp Mol Pathol. 2015 Oct;99(2):297-302. doi: 10.1016/j.yexmp.2015.07.012. Epub 2015 Jul 29. Author information 1 Department of Pathology, Shanxi Cancer Hospital and Shanxi Medical University, Taiyuan, Shanxi 030013, China. 2 Shanxi Medical University, Taiyuan, Shanxi, 030013, China. 3 Department of Pathology, Shanxi Cancer[…] [ncbi.nlm.nih.gov] Tetrahydrobiopterin Deficiency manifesting diurnal variation, that is, worst when patients become tired or when the dosage or interval for medications is inadequate. [thieme-connect.com] The outcome of patients with disorders of biopterin synthesis can be favorable, with either normal or near-normal cognition, and with some residual neurological symptoms usually [thieme-connect.com] Hartnup Disease Abstract A 14-year-old boy of Arabic origin presented with a pellagra-like rash and neurological manifestations including ataxia, dysarthria, nystagmus, and coma. [ncbi.nlm.nih.gov] Neurologic manifestations include cerebellar ataxia and mental abnormalities. Intellectual disability, short stature, headache, and collapsing or fainting are common. [merckmanuals.com] Cutaneous signs usually precede the neurological manifestations. [namrata.co] Thallium Poisoning Although thallium has a short half-life, these neurologic manifestations commonly progress, even as the blood concentration of thallium decreases. [ncbi.nlm.nih.gov] Acute poisoning tends to produce gastrointestinal (GI) effects, whilst chronic poisoning tends to produce neurological manifestations. [patient.info] The neurologic manifestations of thallium poisoning include a severely painful ascending peripheral neuropathy, autonomic dysfunction, cranial nerve abnormalities, and a toxic [ncbi.nlm.nih.gov] Cerebral Lipidosis […] demonstrated prevention of further neurological manifestations in a young child whose only initial manifestation was disturbed saccadic eye movements [16] Fabry disease Until [emedicine.medscape.com] A case study of combined ERT and SRT revealed improvement of neurological signs in symptomatic patients with Gaucher disease type 3 and, over a 3-year observation period, [emedicine.medscape.com]
