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19 Possible Causes for Neurologic Manifestation, Physiological Neonatal Jaundice, Yellow Discoloration of the Skin

  • Crigler-Najjar Syndrome Type 1

    Before the age of 15, the patient did not manifest any neurological or behavioural dysfunction despite increased bilirubin in serum.[ncbi.nlm.nih.gov] Physiological neonatal jaundice may peak at 85–170 µmol/l and decline to normal adult concentrations within two weeks. Prematurity results in higher levels.[en.wikipedia.org] This leads to jaundice, i.e. yellow discoloration of skin and eyes. Excess bilirubin can also damage the brain, muscles, and nerves.[medindia.net]

  • Neonatal Jaundice

    When to seek medical help “Very high levels of bilirubin can damage the brain (a condition known as kernicterus), which can cause irreversible neurological damage that can[lohud.com] Jaundice, Physiological NeonatalNeonatal Jaundice, Physiological — Severe Jaundice in Newborn — Severe Jaundice in Neonate — Icterus Gravis Neonatorum[mesh.kib.ki.se] Definition Neonatal jaundice is the yellowing discoloration of the skin and sclera of a neonate, which is caused by increased levels of bilirubin in the blood.[bestpractice.bmj.com]

  • Physiological Neonatal Jaundice

    Kernicterus, in both acute and chronic forms, is manifest by a variety of neurologic and cognitive deficits ranging from poor suckling and seizures to low IQ.[vivo.colostate.edu] Published on Jul 10, 2016 Physiological Neonatal Jaundice and Its causes. Physiological Neonatal Jaundice 1. PHYSIOLOGICAL NEONATAL JAUNDICE 10/07/2016 1 2.[slideshare.net] Definition (MSH) Yellow discoloration of the SKIN; MUCOUS MEMBRANE; and SCLERA in the NEWBORN. It is a sign of NEONATAL HYPERBILIRUBINEMIA.[fpnotebook.com]

  • Jaundice

    When to seek medical help “Very high levels of bilirubin can damage the brain (a condition known as kernicterus), which can cause irreversible neurological damage that can[lohud.com] This is called “physiologic” or normal neonatal jaundice. Most infants have this pattern so no testing is needed.[patients.gi.org] Jaundice is a yellow discoloration of the skin and mucous membranes caused by an excess accumulation of bilirubin in the blood.[medcomic.com]

  • Liver Cirrhosis

    Abstract Progressive encephalomyelopathy is a rare neurological complication of chronic liver disease, even manifesting progressive spastic paraparesis.[ncbi.nlm.nih.gov] […] history of alcohol excess, neonatal jaundice, hypertension, or hypercholesterolemia.[atsjournals.org] Yellow discoloration in the skin and eyes (jaundice) Fluid accumulation in your abdomen (ascites) Spiderlike blood vessels on your skin Redness in the palms of the hands[mayoclinic.org]

  • Transient Familial Neonatal Hyperbilirubinemia

    The ultimate goal is to prevent the development of kernicterus—the permanent neurologic consequence of bilirubin deposition in brain tissue; the acute neurologic manifestations[aneskey.com] Preferred Name Fetal and neonatal jaundice, NOS Synonyms Physiologic jaundice in newborn, NOS ID altLabel Physiologic jaundice in newborn, NOS Neonatal jaundice, NOS Foetal[purl.bioontology.org] Jaundice is a yellow discoloration of the skin and eyes caused by hyperbilirubinemia (elevated serum bilirubin concentration).[merckmanuals.com]

  • Rotor Syndrome

    Neurologic manifestations include alteration in mental status, seizures, hemiplegia, paresthesias, visual disturbance, and aphasia Fatigue may accompany the anemia Severe[emedicine.medscape.com] Neonatal jaundice and Breast-milk jaundice Conjugated hyperbilirubinaemia Hepatocellular – Diminished hepatocyte function.[lifeinthefastlane.com] Introduction Jaundice refers to yellow discoloration of the skin, sclera, mucous membranes, and body fluids.[pedsinreview.aappublications.org]

  • Kernicterus

    Background: Kernicterus is a neurologic manifestation of hyperbilirubinemia in the newborn, with premature neonates being more susceptible.[ajnr.org] Nielsen HE, Haase P, Blaabjerg J, Stryhn H, Hilden J: Risk factors and sib correlation in physiological neonatal jaundice. Acta Paediatr Scand 1987;76:504–511.[karger.com] Overview Infant jaundice is yellow discoloration of a newborn baby's skin and eyes.[mayoclinic.org]

  • Crigler-Najjar Syndrome Type 2

    The resulting functional defect has been well characterized with respect to biochemical and neurologic manifestations.[einstein.pure.elsevier.com] Physiological neonatal jaundice may peak at 85–170 µmol/l and decline to normal adult concentrations within two weeks. Prematurity results in higher levels.[en.wikipedia.org] This leads to jaundice, i.e. yellow discoloration of skin and eyes. Excess bilirubin can also damage the brain, muscles, and nerves.[medindia.net]

  • Neonatal Hypoglycemia

    All patients except two manifested parieto-occipital lesions on neuroradiologic images. Neurologic examination was normal in one patient.[ncbi.nlm.nih.gov] Jaundice, Physiological NeonatalNeonatal Jaundice, Physiological — Severe Jaundice in Newborn — Severe Jaundice in Neonate — Icterus Gravis Neonatorum[mesh.kib.ki.se] Six patients had microcephaly; eight manifested visual disturbances. Fourteen patients were mentally retarded. One had a pervasive developmental disorder.[ncbi.nlm.nih.gov]

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