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35 Possible Causes for Neuronal Loss and Gliosis in the Inferior Olives

  • Olivopontocerebellar Atrophy

    There is neuronal loss and gliosis in the inferior olives, pons, cerebellum, substantia nigra, locus ceruleus, striatum and the intermediolateral column of the spinal cord[dizziness-and-balance.com] Microscopic examination of these structures reveals neuronal loss, axon and myelin degeneration, and gliosis.[neuropathology-web.org] Neuropathological examination reveals loss of normal pigmentation in the substantia nigra, OPCA (atrophy of the cerebellum, basis pontis, and inferior olives), and atrophy[neuropathology-web.org]

  • Striatonigral Degeneration

    There is neuronal loss and gliosis in the inferior olives, pons, cerebellum, substantia nigra, locus ceruleus, striatum and the intermediolateral column of the spinal cord[dizziness-and-balance.com] Inferior olives and dentate nucleus were well outlined.[dokumen.tips] Microscopic examination revealed rarefied structure of both putamina, marked loss of large and small neurons, fibrillar gliosis, and proliferation of capillaries (Fig. 1 A[dokumen.tips]

  • Shy Drager Syndrome

    loss, gliosis, and microvacuolation in the involved neuronal systems.[emedicine.medscape.com] Patients with MSA-C primarily have shrinkage of the cerebellum, middle cerebellar peduncles, inferior olives, and basis pontis. [14] Histopathologic findings include neuronal[emedicine.medscape.com]

  • Ataxia

    Microscopic examination of these structures reveals neuronal loss, axon and myelin degeneration, and gliosis.[neuropathology-web.org] In addition, mild secondary neuronal cell loss with gliosis was noted in the dentate nucleus and inferior olive.[doi.org] Neuropathological examination reveals loss of normal pigmentation in the substantia nigra, OPCA (atrophy of the cerebellum, basis pontis, and inferior olives), and atrophy[neuropathology-web.org]

  • Disorder of Fructose Metabolism

    There was marked depletion of cerebellar Purkinje cells, with sparing of the granular layer and neuronal loss in the dentate nuclei and inferior olives.[clinicalgate.com] In both cases, there was diffuse white matter gliosis, with focal areas of infarction.[clinicalgate.com]

  • Spinocerebellar Ataxia Type 13

    loss and gliosis.[link.springer.com] Pronounced neuronal loss was identified in the Purkinje cell layer of the rostal vermis, the dentate nuclei and inferior olives; the surrounding white matter showed myelin[link.springer.com] No clear loss of motor neurons was observed in the spinal cord.[link.springer.com]

  • Generalized Myotonia of Thomsen

    Microscopic examination of these structures reveals neuronal loss, axon and myelin degeneration, and gliosis.[neuropathology-web.org] Neuropathological examination reveals loss of normal pigmentation in the substantia nigra, OPCA (atrophy of the cerebellum, basis pontis, and inferior olives), and atrophy[neuropathology-web.org]

  • Dentatorubral-Pallidoluysian Atrophy

    Neuropathological examination showed severe neuronal loss associated with gliosis in the inferior olive and cerebellar Purkinje cell layer.[doi.org] Moderate neuronal loss and gliosis were also found in the inferior olive and Purkinje cell layer, whereas pathological changes in the cerebral cortex and basal ganglia were[doi.org] Neuropathologically, severe neuronal loss and gliosis were seen in the dentate nucleus.[doi.org]

  • Myopathic Carnitine Deficiency

    loss in the dentate, inferior olive Diffuse gliosis in cerebellar white matter and brain Differential Diagnosis of MERRF Unverricht-Lundborg disease (Baltic myoclonus): AR-chromosome[neurodiffdx.com] Ataxia Degeneration of posterior columns and cerebellum Exercise intolerance Lactic acidosis Large lipomas in patients and relatives Pes Cavus Impaired sensation Pathology: Neuronal[neurodiffdx.com]

  • Adult-Onset Autosomal Recessive Cerebellar Ataxia

    Microscopic examination of these structures reveals neuronal loss, axon and myelin degeneration, and gliosis.[neuropathology-web.org] Neuropathological examination reveals loss of normal pigmentation in the substantia nigra, OPCA (atrophy of the cerebellum, basis pontis, and inferior olives), and atrophy[neuropathology-web.org]

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