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11 Possible Causes for Neuronal Loss and Gliosis in the Inferior Olives, Numbness of the Hand

  • Olivopontocerebellar Atrophy

    There is neuronal loss and gliosis in the inferior olives, pons, cerebellum, substantia nigra, locus ceruleus, striatum and the intermediolateral column of the spinal cord[dizziness-and-balance.com] Other symptoms may include muscle spasms or weakness and stiffness of the muscles; numbness or tingling of the hands or feet; tremor (shaking) of the hand or arm; reduction[alyshia.com] Microscopic examination of these structures reveals neuronal loss, axon and myelin degeneration, and gliosis.[neuropathology-web.org]

  • Cerebellar Ataxia with Peripheral Neuropathy Type 2

    Microscopic examination of these structures reveals neuronal loss, axon and myelin degeneration, and gliosis.[neuropathology-web.org] The numbness is noted in the 4th and 5th digit of the hand.[webmd.com] […] in the hands or feet Open sores and unintentional self-injury Loss of taste Trouble breathing, digesting, or swallowing Blotching of the skin Bone erosions The signs and[dovemed.com]

  • Ataxia

    Microscopic examination of these structures reveals neuronal loss, axon and myelin degeneration, and gliosis.[neuropathology-web.org] Patients suffering from peripheral neuropathy also experience numbness and tingling in their hands and feet.[en.wikipedia.org] Some of the SCAs (SCA1, 2, 3, 4, 7 and 8) also cause peripheral neuropathy (damage to the peripheral nerves which causes the patient to have numbness or tingling in the hands[bcm.edu]

  • Hereditary Cerebellar Degeneration

    Microscopic examination of these structures reveals neuronal loss, axon and myelin degeneration, and gliosis.[neuropathology-web.org] Some of the SCAs (SCA1, 2, 3, 4, 7 and 8) also cause peripheral neuropathy (damage to the peripheral nerves which causes the patient to have numbness or tingling in the hands[bcm.edu] ,lack of balance and coordination, numbness in right leg after standing for more than 20 minutes, and a tendency to drag my right toes.[medhelp.org]

  • Paraneoplastic Neurologic Syndrome

    In addition, mild secondary neuronal cell loss with gliosis was noted in the dentate nucleus and inferior olive.[jneuroinflammation.com] […] feeling of burning in hands and feet.[rarediseases.org] Histopathology revealed only sporadic T cells and macrophages but a total loss of PCs accompanied by mild Bergmann gliosis.[jneuroinflammation.com]

  • Generalized Myotonia of Thomsen

    Microscopic examination of these structures reveals neuronal loss, axon and myelin degeneration, and gliosis.[neuropathology-web.org] Other symptoms may include muscle spasms or weakness and stiffness of the muscles; numbness or tingling of the hands or feet; tremor (shaking) of the hand or arm; reduction[puneataxiasupport.wordpress.com] Neuropathological examination reveals loss of normal pigmentation in the substantia nigra, OPCA (atrophy of the cerebellum, basis pontis, and inferior olives), and atrophy[neuropathology-web.org]

  • Autosomal Recessive Spinocerebellar Ataxia 8

    Microscopic examination of these structures reveals neuronal loss, axon and myelin degeneration, and gliosis.[neuropathology-web.org] Some of the SCAs (SCA1, 2, 3, 4, 7 and 8) also cause peripheral neuropathy (damage to the peripheral nerves which causes the patient to have numbness or tingling in the hands[bcm.edu] Neuropathological examination reveals loss of normal pigmentation in the substantia nigra, OPCA (atrophy of the cerebellum, basis pontis, and inferior olives), and atrophy[neuropathology-web.org]

  • Spinocerebellar Ataxia Type 5

    loss and gliosis.[link.springer.com] […] sensation in the extremities of limbs and hands), optic neuropathy, and deafness.[encyclopedia.com] Pronounced neuronal loss was identified in the Purkinje cell layer of the rostal vermis, the dentate nuclei and inferior olives; the surrounding white matter showed myelin[link.springer.com]

  • Cognitive Impairment with or without Cerebellar Ataxia

    Microscopic examination of these structures reveals neuronal loss, axon and myelin degeneration, and gliosis.[neuropathology-web.org] Some of the SCAs (SCA1, 2, 3, 4, 7 and 8) also cause peripheral neuropathy (damage to the peripheral nerves which causes the patient to have numbness or tingling in the hands[bcm.edu] Neuropathological examination reveals loss of normal pigmentation in the substantia nigra, OPCA (atrophy of the cerebellum, basis pontis, and inferior olives), and atrophy[neuropathology-web.org]

  • Autosomal Dominant Sensory Ataxia

    Microscopic examination of these structures reveals neuronal loss, axon and myelin degeneration, and gliosis.[neuropathology-web.org] Some of the SCAs (SCA1, 2, 3, 4, 7 and 8) also cause peripheral neuropathy (damage to the peripheral nerves which causes the patient to have numbness or tingling in the hands[bcm.edu] […] sensation in the extremities of limbs and hands), optic neuropathy, and deafness.[encyclopedia.com]

Further symptoms