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231 Possible Causes for Neuronal Loss and Gliosis in the Inferior Olives, Onset in Adolescence or Young Adulthood

  • Adult-Onset Autosomal Recessive Cerebellar Ataxia

    Microscopic examination of these structures reveals neuronal loss, axon and myelin degeneration, and gliosis.[neuropathology-web.org] Neuropathological examination reveals loss of normal pigmentation in the substantia nigra, OPCA (atrophy of the cerebellum, basis pontis, and inferior olives), and atrophy[neuropathology-web.org]

  • Ataxia

    Microscopic examination of these structures reveals neuronal loss, axon and myelin degeneration, and gliosis.[neuropathology-web.org] SCA11 progresses slowly over decades, with onset between adolescence and young adulthood.[encyclopedia.com] In addition, mild secondary neuronal cell loss with gliosis was noted in the dentate nucleus and inferior olive.[doi.org]

  • Hereditary Cerebellar Degeneration

    Microscopic examination of these structures reveals neuronal loss, axon and myelin degeneration, and gliosis.[neuropathology-web.org] SCA11 progresses slowly over decades, with onset between adolescence and young adulthood.[encyclopedia.com] Neuropathological examination reveals loss of normal pigmentation in the substantia nigra, OPCA (atrophy of the cerebellum, basis pontis, and inferior olives), and atrophy[neuropathology-web.org]

  • Spinocerebellar Ataxia Type 5

    loss and gliosis.[link.springer.com] SCA11 progresses slowly over decades, with onset between adolescence and young adulthood.[encyclopedia.com] Pronounced neuronal loss was identified in the Purkinje cell layer of the rostal vermis, the dentate nuclei and inferior olives; the surrounding white matter showed myelin[link.springer.com]

  • Cerebellar Ataxia with Peripheral Neuropathy Type 2

    Microscopic examination of these structures reveals neuronal loss, axon and myelin degeneration, and gliosis.[neuropathology-web.org] SCA11 progresses slowly over decades, with onset between adolescence and young adulthood.[encyclopedia.com] Neuropathological examination reveals loss of normal pigmentation in the substantia nigra, OPCA (atrophy of the cerebellum, basis pontis, and inferior olives), and atrophy[neuropathology-web.org]

  • Alcohol Abuse

    […] of puberty, it is now known that the brain continues to develop throughout adolescence and into young adulthood. 6 Longitudinal research demonstrates that higher-order association[dx.doi.org] […] designated a period of “emerging adulthood.” 5 Biological Development Brain Development Although it was once thought that human brain development was largely complete by the onset[dx.doi.org]

    Missing: Neuronal Loss and Gliosis in the Inferior Olives
  • Iron Deficiency Anemia

    In young pregnant women, the onset of pica frequently occurs during their first pregnancy in late adolescence or early adulthood.[emedicine.com] Adolescents and adults most often ingest clay or soil.[emedicine.com]

    Missing: Neuronal Loss and Gliosis in the Inferior Olives
  • Diabetes Mellitus

    […] early-onset diabetes (usually in adolescence or early adulthood) from a single gene mutation.[stanfordchildrens.org] The most common types of monogenic diabetes are neonatal diabetes and maturity-onset diabetes of the young (MODY).[niddk.nih.gov] Although often misdiagnosed initially as the more common type 1 or type 2 diabetes, maturity-onset diabetes of the young (MODY) is a group of diseases characterized by inherited[stanfordchildrens.org]

    Missing: Neuronal Loss and Gliosis in the Inferior Olives
  • Young Adult-Onset Distal Hereditary Motor Neuropathy

    Both CMT2D and dSMA-V (dHMN5A) are usually characterized by disease onset in adolescence or young adulthood and initial manifestations of weakness and atrophy of the hand[journals.plos.org] […] prenatal-onset to late adulthood) distal SMALED1, CMT2O FBXO38 adolescence or adulthood distal HMN2D GARS adolescence or early adulthood distal HMN5, CMT2D HINT1 childhood[invitae.com] […] typically occurs during adolescence or young adulthood, initially manifesting as weakness and atrophy of the hand muscles.[journals.plos.org]

    Missing: Neuronal Loss and Gliosis in the Inferior Olives
  • Infectious Mononucleosis

    ., childhood versus adolescence/early adulthood when infection is more likely to manifest as infectious mononucleosis (IM).[ncbi.nlm.nih.gov] We sought to determine the influence of young adult-onset IM on the prostate by measuring prostate-specific antigen (PSA) as a marker of prostate inflammation/damage among[ncbi.nlm.nih.gov]

    Missing: Neuronal Loss and Gliosis in the Inferior Olives

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