Possible Causes for neurophysiologic abnormalities Congenital Neuronal Ceroid Lipofuscinosis Cathepsin D (Ctsd) is a ubiquitously expressed aspartic protease functioning primarily in the acidic endosomal/lysosomal cell compartment. At an age of 26 1 days, mice with constitutive Ctsd deficiency (Ctsd(-/-)) die from a neurodegenerative lysosomal storage disease equivalent to the congenital neuronal ceroid[…] [ncbi.nlm.nih.gov] Insomnia It is possible that abnormal limb movements during sleep may be associated with an unidentified neurophysiological alteration in micro-structure of the EEG sleep pattern. [web.archive.org] Alcohol Abuse Clinical Neurophysiology. 2007; 118 :2128–2148. [ PMC free article ] [ PubMed ] [ Google Scholar ] Polich J, Pollock V, Bloom FE. [ncbi.nlm.nih.gov] Journal of Abnormal Psychology. 1974; 83 :418–425. [ PubMed ] [ Google Scholar ] Polich J. Updating P300: An integrative theory of P3a and P3b. [ncbi.nlm.nih.gov] Polyneuropathy Persistent neuromuscular and neurophysiologic abnormalities in long-term survivors of prolonged critical illness. Crit Care Med 2003, 31: 1012–1016. [link.springer.com] Persistent neuromuscular and neurophysiologic abnormalities in long-term survivors of prolonged critical illness. Crit Care Med 2003; 31: 1012-6. [medigraphic.com] Persistent neuromuscular and neurophysiologic abnormalities in long-term survivors of prolonged critical illness. Crit Care Med. 2003;31(4):1012-6. 30. [revistas.fucsalud.edu.co] Neuropathy The neurophysiological evaluation shows abnormal vibratory thresholds, and quantitative sensory testing may also reveal elevated thermal thresholds at the hands and feet [ [ncbi.nlm.nih.gov] […] approach with quantitative sensory testing in patients receiving bortezomib reveals increased touch thresholds, increased slotted pegboard time, abnormal cold pain thresholds [bloodjournal.org] […] potentials and increased size and complexity of motor unit potentials may also be evident in electromyographic testing with concentric needle electrodes. 5 Finally, the neurophysiologic [bloodjournal.org] Restless Legs Syndrome Our neurophysiological results imply that the abnormal activities in the frontal region results in a cognitive deficit in RLS patients, which should be compared with neuropsychological [ncbi.nlm.nih.gov] Dysthymic Disorder […] uncovered with TRH-TSH tests, among others, indicate that many people with dysthymic disorders exhibit, at baseline, the neurophysiological patterns found with acute MDD, [scielo.br] Dysthymic patients and those with MDD also sought few treatment environments for their conditions.38 According to Akiskal,5 data from sleeping electroencephalogram (EEG) and abnormalities [scielo.br] Osteoporosis Eichler, Natural history of neurological abnormalities in cerebrotendinous xanthomatosis, Journal of Inherited Metabolic Disease, 41, 4, (647-656), (2018). Bianca M. L. [doi.org] Debs, Foudil Lamari, Vincent Perlbarg, Emmanuel Roze, Bertrand Degos and Fanny Mochel, Treatment with chenodeoxycholic acid in cerebrotendinous xanthomatosis: clinical, neurophysiological [doi.org] Presbycusis The majority of older people had presbycusis and someone had auditory perceptual abnormalities specially in noise. [hindawi.com] Neurophysiological evidence of delayed neural timing and decreased temporal processing ability with age may be consequent to decreased levels of inhibitory neurotransmitters [hindawi.com] Polycystic Ovary Syndrome What follows is an integrated picture relating normal and abnormal structure, function and clinical manifestations. [dartmouth.edu] The specific neuromuscular diagnosis is made by history, examination and supported by laboratory studies, neurophysiology and, in selected cases, muscle and nerve biopsies [dartmouth.edu] Diabetes Mellitus Abnormal results of nerve-conduction studies were defined as abnormal results of neurophysiologic tests in at least two peripheral nerves. [doi.org] The analysis included all patients from either cohort who did not have the abnormality in question at base line. [doi.org] Prevalence of Abnormal Clinical Neurologic Examinations, Abnormal Results of Nerve-Conduction Studies, and Abnormal Autonomic-Nerve Studies at Five Years in Patients Receiving [doi.org] Anxiety Disorder Neurophysiology Abnormalities – hippocampus in contextual fear conditioning Conditioned Leaning: Behaviorist believes that people learn fear from his environment. [psychologyclinix.com] Cardiac Arrhythmia […] in electrolytes, such as hypokalemia and hypomagnesemia, often due to diuretics; changes in pH or P o 2 ; the influence of central and peripheral neurophysiological actions [doi.org] This probably relates, at least in part, to the transient nature of many risk factors, such as myocardial ischemia and reperfusion; hemodynamic dysfunction; abnormalities [doi.org] and the transient effects of toxins such as drugs 28 or alcohol. 1 2 Structural cardiac abnormalities of the myocardium, coronary arteries, or cardiac nerves provide the [doi.org] Tarsal Tunnel Syndrome Eight feet (7%) were without neurographic abnormalities. [ncbi.nlm.nih.gov] T1 and T5 SCV were abnormal in 82 and 73% of cases, respectively, and comparative tests were abnormal in a further 7% of cases. DML was abnormal in 82 feet (73.9%). [ncbi.nlm.nih.gov] The distribution of feet in neurophysiological classes was: stage 0, 7%; stage 1, 9%; stage 2, 10%; stage 3, 39%; stage 4, 32%; stage 5, 3%. [ncbi.nlm.nih.gov] Autonomic Neuropathy A neurophysiological abnormality involved an absence of sensory action potentials with relatively normal motor nerve conduction velocities. [ncbi.nlm.nih.gov] abnormalities. [emedicine.medscape.com] The autonomic nervous system modulates numerous body functions; therefore, autonomic dysfunction may manifest with numerous clinical phenotypes and various laboratory and neurophysiologic [emedicine.medscape.com] Median Neuropathy RESULTS: 132/158 hands (83.5%) had abnormal electrophysiological studies. [ncbi.nlm.nih.gov] Some studies have also reported abnormal neurophysiological findings in the median nerves of diabetic patients [14], [15]. [journals.plos.org] Routine tests were consistent with neurophysiological carpal tunnel syndrome in 66 (41.8%) hands and 63 of these 66 (95.5%) had prolonged 2L-INT latency difference. [ncbi.nlm.nih.gov] Entrapment Neuropathy […] scapular fracture.21 Neurophysiologic evaluation should be performed to confirm the diagnosis of entrapment neuropathy of the suprascapular nerve.19·22-3 Electromyography [healio.com] Radiographs can help rule out other causes of shoulder pain such as osteoarthrosis and may identify an abnormality of the scapula causing the nerve entrapment such as an old [healio.com] Migraine Frontiers in Pharmacology: "Treating chronic migraine with neuromodulation: The role of neurophysiological abnormalities and maladaptive plasticity." [onhealth.com] Marina de Tommaso, Effects of antiepileptic drugs on neurophysiologic abnormalities subtending migraine, Drug Development Research, 68, 6, (369-375), (2007). [doi.org] Lumbar Radiculopathy Neurophysiologic abnormalities had improved on reassessment. [ncbi.nlm.nih.gov] Patients were sorted into 5 groups based on the type and distribution of neurophysiologic abnormalities: from 0 (no abnormalities) to 4 (denervation signs in 2 lower limb [ncbi.nlm.nih.gov] SETTING: A referral center for neurophysiologic evaluation. [ncbi.nlm.nih.gov] Strabismus KEYWORDS: neurophysiology; pursuit; saccade; strabismus; vision [ncbi.nlm.nih.gov] These studies provide compelling evidence that a disturbance of binocular vision during a sensitive period early in life, whatever the cause, results in a cascade of abnormalities [ncbi.nlm.nih.gov] Whiplash Injury (or functional) deficits and must be correlated with the anatomical (or structural) abnormalities as well as the physical examination in patients with suspected cervical [practicalpainmanagement.com] […] requiring surgery.1 Electromyography (EMG) and nerve conduction velocity studies (including somatosensory evoked responses and quantitative sensory testing) can evaluate the neurophysiologic [practicalpainmanagement.com] Carpal Tunnel Syndrome Many clinical neurophysiology laboratories are now using ultrasonography as an adjunct to electrodiagnostic studies. [emedicine.com] Ultrasonography potentially can identify space-occupying lesions in and around the median nerve, confirm abnormalities in the median nerve (eg, increased cross-sectional area [emedicine.com] Fibromyalgia (CSS). [3, 4] Indeed, fibromyalgia can now be considered a neurosensory disorder characterized in part by abnormalities in pain processing by the central nervous system [emedicine.com] However, basic and clinical investigations have clarified the neurophysiologic bases for fibromyalgia and led to its current classification as a central sensitivity syndrome [emedicine.com] Transient Ischemic Attack for identifying abnormal aging or tracking the progression of a dementia) Relationship to clinical neurophysiology[edit] In some countries, e.g. [en.wikipedia.org] Ondine Syndrome 1965, Neurophysiological studies of abnormal night sleep and the Pickwickian syndrome. [link.springer.com] Chronic Fatigue Syndrome In line with the hyperarousal theory of primary insomnia, patients were found to have abnormally high regional brain activity during sleep compared to controls subjects. 94 [doi.org] including primary insomnia, 90 OSA, 91, 92 and depression. 93 Particularly in primary insomnia, functional neuroimaging studies during sleep have helped understand the neurophysiological [doi.org] Diabetic Polyneuropathy Normal deviate (from percentiles) composite scores of NC included: representative of neurophysiological abnormalities; sensitive and specific for diagnosis and useful for [ncbi.nlm.nih.gov] Diagnostic criteria for DPN were at least two abnormalities in clinical neurophysiological examinations and electrophysiological testing (H-reflex and nerve conduction velocity [ncbi.nlm.nih.gov] Discriminant analysis of various concentric needle-EMG and macro-EMG parameters in detecting myopathic abnormality. Clinical Neurophysiology 113:1423-8 13. [ispub.com] Congenital Malabsorption of Folic Acid Steinschneider M, Sherbany A, Pavlakis S, et al. (1990) Congenital folate malabsorption: reversible clinical and neurophysiologic abnormalities. Neurology 40: 1315. [els.net] Congenital folate malabsorption: reversible clinical and neurophysiologic abnormalities. Neurology. 1990; 40 :1315. [ PubMed : 2381546 ] Su PC. [ncbi.nlm.nih.gov] Neurogenic Bladder Neurophysiology of the Lower Urinary Tract [ajmc.com] […] techniques must be individualized in patients with spina bifida to preserve both renal function and quality of life.4,20 Diagnosis and Assessment of Neurogenic Bladder Normal and Abnormal [ajmc.com] Temporal Lobe Epilepsy Bumanglag, Robert Schwarcz and Michael Frotscher, Abnormal dentate gyrus network circuitry in temporal lobe epilepsy, Epilepsia, 51, s5, (41-41), (2010). [doi.org] Victor Nadler, High Ratio of Synaptic Excitation to Synaptic Inhibition in Hilar Ectopic Granule Cells of Pilocarpine-Treated Rats, Journal of Neurophysiology, 104, 6, (3293 [doi.org]
