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12 Possible Causes for Neutrophil Count Decreased, Peripheral T Cells Decreased, Pertussis

  • Influenza

    OBJECTIVES: Influenza and pertussis vaccination programmes have been in place for pregnant women in the UK since 2009 and 2012, respectively.[ncbi.nlm.nih.gov] In contrast, IL-1R1 / mice showed a dramatic decrease in CD4 T-cell proliferation, suggesting that efficient T-helper cell priming in peripheral organs is dependent on a functional[doi.org] We describe diagnostic testing use among pertussis and influenza-related paediatric ICU admissions between 01 January 1997 and 31 December 2013. This work is copyright.[ncbi.nlm.nih.gov]

  • Graves Disease

    Berbers and Anne-Marie Buisman , Whole-cell or acellular pertussis vaccination in infancy determines IgG subclass profiles to DTaP booster vaccination , Vaccine , 36 , 2 ,[doi.org] Notably, HLA-DR14, a known risk factor for GD in Japanese individuals and the decreased regulatory T-cell numbers that were seen in the pediatric case, may affect the early[ncbi.nlm.nih.gov] Vaccination , The Pediatric Infectious Disease Journal , 36 , 9 , (e223) , (2017) .[doi.org]

  • Pancytopenia

    During the 2008–2012 pertussis epidemic in Australia, pertactin (Prn)–negative Bordetella pertussis emerged.[cdc.gov] Blood Film 1.RBC morphology ( size & shape) 2.WBC and RBC precursor 3.Platelets count & size 4.Abnormal increase or decrease granulation in Neutrophil 5.[slideshare.net] Immunophenotyping of peripheral white blood cells showed a marked decrease of CD4 T-lymphocytes (7%), B-lymphocytes (1%), and natural killer cells (2%), along with major increase[scielo.br]

  • Visceral Leishmaniasis

    […] by a bacterial molecule that stimulates interleukin 10 production by dendritic cells: a novel strategy for evasion of protective T helper type 1 responses by Bordetella pertussis[doi.org] However, the frequency of Teff cells at disease site (BMMNCs) is decreased as compared to peripheral compartment (PBMCs) (Mean SEM, p   0.023, paired t test ). ii) FACS plot[doi.org] Production of ROI and RNI required T cell IFN-γ production ( 18 ).[jimmunol.org]

  • Lymphocytopenia

    Witvliet MH, Vogel ML, Wiertz EJ, Poolman JT: Interaction of pertussis toxin with human T lymphocytes. Infect Immun 60:5085, 1992. 58.[medtextfree.wordpress.com] D72 Other disorders of white blood cells D72.0 Genetic anomalies of leukocytes D72.8 Other specified disorders of white blood cells D72.81 Decreased white blood cell count[icd10data.com] Flow cytometry immunophenotyping of peripheral blood lymphocytes was investigated in order to analyze monoclonality of B or T cells and showed a decreased ratio of the CD4[pubs.sciepub.com]

  • Viral Meningitis

    It's given as a single injection to protect your baby against six serious childhood diseases: diphtheria tetanus whooping cough (pertussis) polio Hib (Haemophilus influenzae[nhsdirect.wales.nhs.uk] If the absolute neutrophil count falls below 500/mm3, decreasing the aciclovir dose or administering granulocyte colony stimulating factor (GCSF) should be considered.[ncbi.nlm.nih.gov] Moreover, negative PPD skin reaction and decreased peripheral lymphocyte and active T cell count were observed.[jstage.jst.go.jp]

  • Multiple Sclerosis

    Philpott, The Inflammasome Pyrin Contributes to Pertussis Toxin-Induced IL-1β Synthesis, Neutrophil Intravascular Crawling and Autoimmune Encephalomyelitis, PLoS Pathogens[doi.org] count decrease and infection occurrence was detected [ 71 ].[dx.doi.org] Immunologic changes included a marked decrease in proliferation of interferon γ–producing myelin-reactive CD4 T cells in peripheral blood and decreased titers of myelin-specific[oadoi.org]

  • Lymphopenic Agammaglobulinemia - Short-Limbed Dwarfism Syndrome

    Bordetella pertussis plays an important role in respiratory infections. G lamblia and Campylobacter species are involved in GI manifestations.[emedicine.medscape.com] For patients made severely neutropenic by cancer chemotherapy, the risk is greater when the neutrophils are decreasing than with similar counts when neutrophils are increasing[oncohemakey.com] Decreased AIRE function allows autoreactive T cells to escape the thymus in to the periphery.[aacijournal.biomedcentral.com]

  • Subacute Sclerosing Panencephalitis

    During the 2008–2012 pertussis epidemic in Australia, pertactin (Prn)–negative Bordetella pertussis emerged.[doi.org] The CBC revealed slightly decreased hemoglobin and increased neutrophils on the differential count.[cureus.com] (Th2) cytokines by peripheral blood mononuclear cells in response to live measles, mumps or varicella virus.[actamedicaphilippina.com.ph]

  • Hematopoietic Stem Cell Transplantation

    6 mo Influenza vaccination each autumn ... 12 mo Commence if no evidence of active or chronic GVHD observed 3 doses at intervals of 1-2 mo: diphtheria/tetanus/acellular pertussis[emedicine.medscape.com] Immunological Recovery Analysis of leukocyte and neutrophil counts in peripheral blood obtained before and after treatment showed a decrease in leukocytes at 12 months after[diabetes.diabetesjournals.org] Ten patients with symptomatic SCD underwent CD34 cell-selected, T-cell–depleted peripheral blood stem cell transplantation from a mismatched family member or unrelated donor[bloodadvances.org]

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