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15 Possible Causes for Neutrophil Count Decreased, Polychromasia in Peripheral Blood Smear

  • Secondary Myelofibrosis

    Platelet counts initially may be high, normal, or decreased; however, thrombocytopenia tends to supervene as the disorder progresses. 6. 6 MYELOFIBROSIS BY DR .MAGDI AWAD[slideshare.net] The peripheral smear of patients with primary myelofibrosis includes red blood cells of variable shape (including tear drop cells) and size and variable degrees of polychromasia[mpncanada.com] Neutrophils are immature and myeloblasts may be present even in the absence of acute leukemia. Platelets may be high, normal or decreased.[clinicaladvisor.com]

  • Autoimmune Hemolytic Anemia

    Peripheral blood smear showed polychromasia and spherocytosis. Haptoglobin level was 0.06 g/L ( N 0.16-2). Both hemoglobin electrophoresis and G6PD level were normal.[jahjournal.org] Red blood cell agglutination, polychromasia, target cells and spherocytes were seen on a peripheral smear.[doi.org]

  • Pancytopenia

    Blood Film 1.RBC morphology ( size & shape) 2.WBC and RBC precursor 3.Platelets count & size 4.Abnormal increase or decrease granulation in Neutrophil 5.[slideshare.net] blood smear examination for which Leishman stain was used.[mjdrdypu.org] The criteria for autoimmune neutropenia diagnosis are as follows: A decrease in the circulating absolute neutrophil count to 1 caused by serum anti-neutrophil antibodies.[smjonline.org]

  • Sideroblastic Anemia

    Blood Smear Peripheral blood smear images .[imagebank.hematology.org] Showing marked anisopoikilocytosis, basophilic stippling, polychromasia and nRBCs.[imagebank.hematology.org] […] ineffective erythropoiesis Hereditary and Acquired Sideroblastic Anemias Published Date: 02/25/2016 Download reference case 8 year old female with congenital sideroblastic anemia Peripheral[imagebank.hematology.org]

  • Congenital Dyserythropoietic Anemia

    The extent of the patient’s bone marrow hypocellularity, her haemoglobin concentration, and neutrophil and platelet counts place her disorder in the severe aplastic anemia[slideshare.net] Anisopoikilocytosis with tear-drop forms, polychromasia, basophilic stippling in peripheral blood smear, erythroid hyperplasia with megaloblastoid changes, binucleated cells[ncbi.nlm.nih.gov] […] category had a mild hypochromic (decreased mean cell hemoglobin concentration) and microcytic (decreased mean cell volume) anemia with target cells and basophilic stippling[slideshare.net]

  • Acquired Hemolytic Anemia

    D720Genetic anomalies of leukocytes D721Eosinophilia D72810Lymphocytopenia D72818Other decreased white blood cell count D72819Decreased white blood cell count, unspecified[cms.gov] blood smear : spherocytes, polychromasia Coombs test : positive Cold agglutinins titer C3 and C4 ; (due to complement activation) Prognosis: spontaneous remission within[amboss.com] […] drug-induced agranulocytosis D703Neutropenia due to infection D704Cyclic neutropenia D708Other neutropenia D709Neutropenia, unspecified D71Functional disorders of polymorphonuclear neutrophils[cms.gov]

  • Myelofibrosis

    Platelet counts initially may be high, normal, or decreased; however, thrombocytopenia tends to supervene as the disorder progresses. 6. 6 MYELOFIBROSIS BY DR .MAGDI AWAD[slideshare.net] The peripheral smear of patients with primary myelofibrosis includes red blood cells of variable shape (including tear drop cells) and size and variable degrees of polychromasia[mpncanada.com] Neutrophils are immature and myeloblasts may be present even in the absence of acute leukemia. Platelets may be high, normal or decreased.[clinicaladvisor.com]

  • Hemoglobin SC Disease

    During hydroxyurea treatment, the white-cell count, absolute neutrophil count, and absolute reticulocyte count significantly decreased, reflecting the intended mild bone marrow[doi.org] Sickle and target cells, polychromasia, and sometimes Howell–Jolly bodies are detected on peripheral blood smears. Results of sickle cell solubility tests are positive.[clinchem.aaccjnls.org] counts fell. 3, 4 In SCA, HbF levels are inversely related to mortality. 1 Decreased morbidity due to hydroxyurea could be associated with reduced mortality.[dx.doi.org]

  • Hereditary Sideroblastic Anemia

    D720Genetic anomalies of leukocytes D721Eosinophilia D72810Lymphocytopenia D72818Other decreased white blood cell count D72819Decreased white blood cell count, unspecified[cms.gov] Blood Smear Peripheral blood smear images .[imagebank.hematology.org] […] drug-induced agranulocytosis D703Neutropenia due to infection D704Cyclic neutropenia D708Other neutropenia D709Neutropenia, unspecified D71Functional disorders of polymorphonuclear neutrophils[cms.gov]

  • Hemolytic Anemia due to a Disorder of Glycolytic Enzymes

    D720Genetic anomalies of leukocytes D721Eosinophilia D72810Lymphocytopenia D72818Other decreased white blood cell count D72819Decreased white blood cell count, unspecified[cms.gov] blood smear : spherocytes, polychromasia Coombs test : positive Cold agglutinins titer C3 and C4 ; (due to complement activation) Prognosis: spontaneous remission within[amboss.com] The peripheral blood smear post-splenectomy often shows crenated or spiculated spherocytes and marked polychromasia.[clinicaladvisor.com]

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