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3,199 Possible Causes for Neutrophil Count Decreased, Splenomegaly, UDP-GlcNAc Decreased

  • Immunodeficiency Type 23

    Impaired function of PGM3 is demonstrated by decreased enzyme activity, reduced UDP-GlcNAc and reduced N-linked glycosylation and O-linked glycosylation [4] PGM3 is composed[en.wikipedia.org] This disorder is characterized by yellowing of the skin and whites of the eyes (jaundice), an abnormally large spleen (splenomegaly), gallstones (cholelithiasis), premature[rarediseases.org] […] blood lymphocyte number Low lymphocyte number [ more ] 0001888 Neutropenia Low blood neutrophil count Low neutrophil count [ more ] 0001875 Recurrent respiratory infections[rarediseases.info.nih.gov]

  • Infectious Mononucleosis

    Clinical estimates of splenomegaly are fallible.[ncbi.nlm.nih.gov] In adolescent and adult patients presenting with sore throat, the presence of posterior cervical, inguinal or axillary adenopathy, palatine petechiae, splenomegaly, or atypical[ncbi.nlm.nih.gov] Abdominal ultrasound may be required to assess for splenomegaly.[patient.info]

    Missing: UDP-GlcNAc Decreased
  • Non-Hodgkin Lymphoma

    Computed tomography scan of the chest and abdomen showed paratracheal and subcarinal lymphadenopathy and splenomegaly, with the findings being compatible with lymphoma.[ncbi.nlm.nih.gov] The most common grade 3 adverse events (AEs) were anemia (43%), neutropenia (39%), decreased neutrophil count (32%), febrile neutropenia (31%), decreased white blood cell[onclive.com] Splenomegaly. Hepatomegaly. Intermediate- and high-grade lymphomas: Most patients present with rapidly growing and bulky lymphadenopathy.[patient.info]

    Missing: UDP-GlcNAc Decreased
  • Leukoerythroblastic Anemia

    Symptoms and Signs Myeloid metaplasia may result in splenomegaly, particularly in patients with storage diseases.[merckmanuals.com] THIS IS NOT A TRUE DECREASE BUT RESULTS FROM INCREASED MARGINATION BY NEUTROPHILS.[meddean.luc.edu] […] leukocytosis increased bone marrow production or release of neutrophils; decreased activation of neutrophil adhesion molecules Neutropenia absolute neutrophil count etiology[memorize.com]

    Missing: UDP-GlcNAc Decreased
  • Leukemia

    Five features were present in 50% of children: hepatomegaly (64%), splenomegaly (61%), pallor (54%), fever (53%) and bruising (52%).[ncbi.nlm.nih.gov] […] in the incidence of infection when the neutrophil count increases from less than 0.1 10 9 /L to greater than 0.5 10 9 /L. 11 Although documented infections in HCL patients[bloodjournal.hematologylibrary.org] Leukemia is usually associated with anemia, fever, hemorrhagic episodes, and splenomegaly.[icd9data.com]

    Missing: UDP-GlcNAc Decreased
  • Chronic Lymphocytic Leukemia

    One month later, he presented with progressive leukocytosis (mostly neutrophilia) and splenomegaly.[ncbi.nlm.nih.gov] : 1500/μL absolute neutrophil count, 100000/μL platelets, 11.0 g/dL hemoglobin or 50% improvement for either of these parameters without transfusions or growth factors.[clinicaltrials.gov] In the physical examination, generalized lymphadenopathy and hepato- and/or splenomegaly may be noted.[symptoma.com]

    Missing: UDP-GlcNAc Decreased
  • Rheumatoid Arthritis

    It is extremely rare for RA to present as FS or develop after initially presenting as neutropaenia and splenomegaly.[ncbi.nlm.nih.gov] Other: thyroid disorders, osteoporosis, depression, splenomegaly.[patient.info] We review the existing literature of such cases and emphasise the importance of serological testing for RA in patients presenting with neutropaenia and splenomegaly, even[ncbi.nlm.nih.gov]

    Missing: UDP-GlcNAc Decreased
  • Post-Polycythemia Vera Myelofibrosis

    Our present case suggests the potential risk of TLS development after ruxolitinib treatment, particularly in patients with massive splenomegaly.[ncbi.nlm.nih.gov] Neutrophils are immature and myeloblasts may be present even in the absence of acute leukemia. Platelets may be high, normal or decreased.[clinicaladvisor.com] No reduction in splenomegaly was seen [ 23 ].[jhoonline.biomedcentral.com]

    Missing: UDP-GlcNAc Decreased
  • Primary Myelofibrosis

    Significant thrombopenia ( KEYWORDS: Myelofibrosis; Palliation; Splenic irradiation; Splenomegaly[ncbi.nlm.nih.gov] We report a patient with very advanced myelofibrosis and huge splenomegaly who showed a complete hematological response to low dose thalidomide with reversal of splenomegaly[ncbi.nlm.nih.gov] Splenomegaly may result in left upper quadrant discomfort.[patient.info]

    Missing: UDP-GlcNAc Decreased
  • Systemic Lupus Erythematosus

    […] relapsing illness, with a variety of different presentations. [ 5 , 6 ] Symptoms and signs are often nonspecific - eg, fatigue (can be severe and debilitating), malaise, fever, splenomegaly[patient.info] Normal WBC counts Leukopenia is caused due to decrease in number of WBCs, particularly neutrophils.[news-medical.net] […] relapsing illness, with a variety of different presentations. [ 5, 6 ] Symptoms and signs are often nonspecific - eg, fatigue (can be severe and debilitating), malaise, fever, splenomegaly[patient.info]

    Missing: UDP-GlcNAc Decreased

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