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145 Possible Causes for Nikolsky's Sign

  • Staphylococcal Scalded Skin Syndrome

    […] acute illness in which the Nikolsky's sign can be easily elicited.[ijpd.in] The erythema is followed by cleavage of the upper epidermis in a large sheets mainly in the head, neck and the flexures, with formation of bullae (Nikolsky sign).[ncbi.nlm.nih.gov] After transfer to the intensive care unit because of deteriorating renal function, a sudden onset of widespread flaccid blistering (Nikolsky sign positive) and superficial[ncbi.nlm.nih.gov]

  • Toxic Epidermal Necrolysis

    sign.[ncbi.nlm.nih.gov] Nikolsky's sign is positive in perilesional skin.[ncbi.nlm.nih.gov] Facts : Generally seen in adults History / PE : Erythematous morbilliform eruption Exfoliation of skin Positive Nikolsky's sign (skin falls off with slightest touch/pressure[medlibes.com]

  • Pemphigus

    […] and symptoms Flaccid blisters on face, scalp, upper body, and intertriginous areas Nikolsky sign – applying pressure on blister periphery extends lesion laterally Mucosal[arupconsult.com] Nikolsky's sign can appear on perilesional skin or, in some cases, even on healthy skin.[orpha.net] […] including fogo selvagem – small superficial blisters typically on neck and upper trunk; "cornflake" scale, as in seborrheic distribution No mucosal involvement Positive Nikolsky[arupconsult.com]

  • Erythema Multiforme

    […] involvement, Nikolsky sign) Urticaria (annular lesions) Erythema nodosum Viral exanthems Treatment Supportive care Corticosteroids if severe Treat underlying cause if identified[medbullets.com] sign (as opposed to SJS/TEN) generally mild burning or itchiness; nontender most commonly involves palms/soles backs of hands and feet extensor aspects of forearms and legs[medbullets.com] sign (as opposed to SJS/TEN) Generally mild burning or itchiness; nontender Most commonly involves palms/soles backs of hands and feet extensor aspects of forearms and legs[smartypance.com]

  • Epidermolysis Bullosa Acquisita

    Nikolsky's sign and bulla spreading sign were positive. Minimal atrophy and pigmentary disturbances were evident on healing. Milia were absent.[ijdvl.com] Nikolsky’s sign was positive. In addition, mucosal lesions appeared on the tongue and lips.[omicsonline.org] The Nikolsky and Asboe-Hansen signs (see above) are positive. The crusted lesions may follow an arcuate pattern. Healing occurs without scarring.[plasticsurgerykey.com]

  • Pemphigus Foliaceus

    Nikolsky's sign was positive.[e-ijd.org] Blisters tend to form when the skin is rubbed ( Nikolsky sign ).[dermnetnz.org] Nikolsky's sign was negative. Oral mucosa and genitalia were normal. On the basis of these clinical findings, a diagnosis of IgA pemphigus was considered.[e-ijd.org]

  • Brazilian Pemphigus Foliaceus

    sign).[medical-dictionary.thefreedictionary.com] The regression phase is characterized by these hyperpigmented macules, progressive clearing, and absence of Nikolsky’s sign.[kundoc.com] […] goo sel-va'zhem) [Portuguese, literally “wild fire”], FS An autoimmune disease that causes blistering of the skin of the head, neck or trunk, esp. when the skin is rubbed (Nikolsky's[medical-dictionary.thefreedictionary.com]

  • Bullous Pemphigoid

    The Nikolsky sign, where upper layers of epidermis move laterally with slight pressure or rubbing of skin adjacent to a blister, is negative.[merckmanuals.com] Blister formation occurs between the stratum spinosum and stratum basale, creating thin, easily ruptured lesions with a positive Nikolsky sign.[consultant360.com] Nikolsky’s sign will be present in pemphigus vulgaris and generally absent in bullous pemphigoid. E. What diagnostic tests should be performed?[cancertherapyadvisor.com]

  • Pemphigus Vegetans

    Lesions heal without scarring The Nikolsky sign is positive - this is where firm sliding pressure with a finger will cause an erosion Flexural involvement readily forms vegetating[pcds.org.uk] […] and symptoms Flaccid blisters on face, scalp, upper body, and intertriginous areas Nikolsky sign – applying pressure on blister periphery extends lesion laterally Mucosal[arupconsult.com] Patients with widespread disease may demonstrate the Nikolsky sign, where blisters can be extended into normal-appearing skin by fingertip pressure lateral to the edge of[dermatologyadvisor.com]

  • Pemphigus Vulgaris

    sign .[en.wikipedia.org] The blisters were suspected to represent the Nikolsky's sign.[ncbi.nlm.nih.gov] Extraoral examination of the skin of hand revealed multiple bullae ( Figure 1B , black arrows) with positive Nikolsky sign 1 and Asboe—Hansen sign or Nikolsky sign 2.[academic.oup.com]

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