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179 Possible Causes for Nikolsky's Sign

  • Staphylococcal Scalded Skin Syndrome

    […] acute illness in which the Nikolsky's sign can be easily elicited.[ijpd.in] The erythema is followed by cleavage of the upper epidermis in a large sheets mainly in the head, neck and the flexures, with formation of bullae (Nikolsky sign).[ncbi.nlm.nih.gov] After transfer to the intensive care unit because of deteriorating renal function, a sudden onset of widespread flaccid blistering (Nikolsky sign positive) and superficial[ncbi.nlm.nih.gov]

  • Pemphigus

    Although clinically rare, affected skin displays "Nikolsky's Sign" which means that bullae easily extend into adjacent skin when lateral pressure is placed.[pathwaymedicine.org] sign .[en.wikipedia.org] This is called a positive Nikolsky sign . A skin biopsy is often done to confirm the diagnosis.[nlm.nih.gov]

  • Pemphigus Vulgaris

    sign.[en.wikipedia.org] The blisters were suspected to represent the Nikolsky's sign.[ncbi.nlm.nih.gov] This is called a positive Nikolsky sign . A skin biopsy is often done to confirm the diagnosis.[nlm.nih.gov]

  • Toxic Epidermal Necrolysis

    sign.[ncbi.nlm.nih.gov] Nikolsky's sign is positive in perilesional skin.[ncbi.nlm.nih.gov] Facts : Generally seen in adults History / PE : Erythematous morbilliform eruption Exfoliation of skin Positive Nikolsky's sign (skin falls off with slightest touch/pressure[medlibes.com]

  • Pemphigus Foliaceus

    Piotr Nikolsky. Bullous pemphigoid forms blister between the epidermis and dermis which result in a thicker skin and are negative for Nikolsky sign.[symptoma.com] Nikolsky's sign was positive.[e-ijd.org] Blisters tend to form when the skin is rubbed ( Nikolsky sign ).[dermnetnz.org]

  • Brazilian Pemphigus Foliaceus

    sign).[medical-dictionary.thefreedictionary.com] They will look for an indicator of the condition called Nikolsky’s sign.[healthline.com] […] goo sel-va'zhem) [Portuguese, literally “wild fire”], FS An autoimmune disease that causes blistering of the skin of the head, neck or trunk, esp. when the skin is rubbed (Nikolsky's[medical-dictionary.thefreedictionary.com]

  • Bullous Pemphigoid

    Placing pressure on the bullae do not lead to their extension into underlying skin, and thus the bullae are negative for "Nikolsky Sign".[pathwaymedicine.org] The Nikolsky sign, where upper layers of epidermis move laterally with slight pressure or rubbing of skin adjacent to a blister, is negative.[msdmanuals.com] Skin biopsy and IgG titers Distinguishing Bullous Pemphigoid From Pemphigus Vulgaris Disorder Appearance of Lesion Oral Involvement Itching Nikolsky Sign Prognosis Bullous[msdmanuals.com]

  • Erythema Multiforme

    […] involvement, Nikolsky sign) Urticaria (annular lesions) Erythema nodosum Viral exanthems Treatment Supportive care Corticosteroids if severe Treat underlying cause if identified[medbullets.com] sign (as opposed to SJS/TEN) generally mild burning or itchiness; nontender most commonly involves palms/soles backs of hands and feet extensor aspects of forearms and legs[medbullets.com] sign (as opposed to SJS/TEN) Generally mild burning or itchiness; nontender Most commonly involves palms/soles backs of hands and feet extensor aspects of forearms and legs[smartypance.com]

  • Pemphigus Vegetans

    Lesions heal without scarring The Nikolsky sign is positive - this is where firm sliding pressure with a finger will cause an erosion Flexural involvement readily forms vegetating[pcds.org.uk] […] and symptoms Flaccid blisters on face, scalp, upper body, and intertriginous areas Nikolsky sign – applying pressure on blister periphery extends lesion laterally Mucosal[arupconsult.com] Nikolsky sign was negative.[njcponline.com]

  • Bullous Impetigo

    sign (sheet-like removal of epidermis with sliding pressure) Highly contagious; may occur in outbreaks ( Antonie Van Leeuwenhoek 2009;95:387, Euro Surveill 2009;14:19372[pathologyoutlines.com] sign Localization Face (most common), especially around the nose and mouth Extremities May be pruritic (especially pustules ) but is rarely painful Regional lymphadenopathy[amboss.com] Associated systemic involvement Staphylococcal scalded skin syndrome Cutaneous tenderness, positive Nikolsky sign, large areas of desquamation or exfoliation.[ncbi.nlm.nih.gov]

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