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12 Possible Causes for Nikolsky's Sign, Onset of Skin Lesions at Birth

  • Pemphigus

    Nikolsky’s sign Nikolsky s sign was first described by a Russian dermatologist Pyotr Vasilievich Nikolskiy.[lecturio.com] Epidermolysis bullosa : are often present at birth and the lesions when heal leave scarring of the skin and mucous membrane.[drmhijazy.com] sign .[en.wikipedia.org]

  • Bullous Impetigo

    sign (sheet-like removal of epidermis with sliding pressure) Highly contagious; may occur in outbreaks ( Antonie Van Leeuwenhoek 2009;95:387, Euro Surveill 2009;14:19372[pathologyoutlines.com] Epidermolysis bullosa : are often present at birth and the lesions when heal leave scarring of the skin and mucous membrane.[drmhijazy.com] sign Localization Face (most common), especially around the nose and mouth Extremities May be pruritic (especially pustules ) but is rarely painful Regional lymphadenopathy[amboss.com]

  • Epidermolysis Bullosa

    […] of blistering occurs at birth with a predominantly generalized skin distribution, and is associated with milia, atrophic scarring, and dystrophic or absent nails.[nature.com] The so-called “albopapuloid lesions”, a hallmark feature of Pasini DDEB, characterized by small hypopigmented or flesh-colored papules, are now found to be both an inconstant[nature.com] […] extracutaneous manifestations have been reported. 10 The previously Pasini and Cockayne-Touraine variants of DDEB have been combined under the more inclusive term DDEB. 2 The usual onset[nature.com]

  • Brazilian Pemphigus Foliaceus

    sign).[medical-dictionary.thefreedictionary.com] Epidermolysis bullosa : are often present at birth and the lesions when heal leave scarring of the skin and mucous membrane.[drmhijazy.com] […] goo sel-va'zhem) [Portuguese, literally “wild fire”], FS An autoimmune disease that causes blistering of the skin of the head, neck or trunk, esp. when the skin is rubbed (Nikolsky's[medical-dictionary.thefreedictionary.com]

  • Herlitz Disease

    The infantile form identified in the Holmes County Amish may have its onset before birth with blisters forming in utero and therefore lesions are often present at birth.[wohproject.org] Clinical Characteristics General description (for patients): EBL is one of several serious skin disorders with severe blistering of the skin.[wohproject.org]

  • Pemphigus Erythematosus

    The Nikolsky sign is not specific for pemphigus and may also be observed in staphylococcal scalded skin syndrome and toxic epidermal necrolysis.[clinicaladvisor.com] Epidermolysis bullosa : are often present at birth and the lesions when heal leave scarring of the skin and mucous membrane.[drmhijazy.com] Nikolsky’s sign appeared to be positive, albeit somewhat indistinct.[omicsonline.org]

  • Benign Familial Pemphigus

    sign may be positive 1/3 of cases are sporadic Healing accompanied by hyperpigmentation, but scarring is rare Longitudinal leukonychia (asymptomatic white longitudinal bands[pathologyoutlines.com] Epidermolysis bullosa : are often present at birth and the lesions when heal leave scarring of the skin and mucous membrane.[drmhijazy.com] Lesions are positive for Nikolsky’s sign (lateral pressure of unblistered skin at the periphery of active lesions causes the epidermis to shear off) and for Asboe Hansen’s[dermnet.com]

  • Evan's Syndrome

    ニコルスキー Nikolsky's sign ニコルスキー徴候 Nissl ニッスル Nissl degeneration ニッスル小体変性 Noonan ヌーナン Noonan syndrome ヌーナン症候群 JacquelineAnne Noonan (1021- ) Americanpedicatric cardiologist[jams.med.or.jp] It is the combination of family history of both tylosis and oesophageal cancer, late onset skin lesions (i.e. substantially after birth but before puberty) and, more recently[ojrd.biomedcentral.com] Niemann-Pick ニーマン・ピック Niemann-Pick disease ニーマン・ピック病 AlbertNiemann (1880-1921) German pediatrician and Ludwig Pick (1868-1944) Germanpathologist died in concentrate camp Nikolsky[jams.med.or.jp]

  • Linear Atrophoderma of Moulin

    Nikolsky sign.[quizlet.com] Most of them are nevoid skin lesionspresent at birth or having a later onset. 2,9,11 These includeepidermal nevi (naevus unius lateris, linear porokeratosis),adnexal nevi[docmh.net] (linear sebaceous nevus, linear basal cellnevus), pigmented lesions (systematized linear achromicnevus) and intricated nevi of the connective tissue (angio-lipomatous nevus[docmh.net]

  • Transient Bullous Dermolysis of the Newborn

    ’s sign.[clinicalgate.com] […] of blistering occurs at birth with a predominantly generalized skin distribution, and is associated with milia, atrophic scarring, and dystrophic or absent nails.[nature.com] […] bullosa simplex Lethal acantholytic EB (LAEB) is an extremely rare subtype of EB. 8 – 10 Affected infants present at birth with rapidly progressive erosions with a positive Nikolsky’s[clinicalgate.com]

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