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114 Possible Causes for Nitrofurantoin Toxicity

  • Nitrofurantoin Toxicity

    Abstract The toxicity of nitrofurantoin was studied on human WI-38 fibroblasts: this chemical was lethal when added at concentrations higher than 5.10(-5) M in the culture[ncbi.nlm.nih.gov] TY - JOUR T1 - Mechanism of nitrofurantoin toxicity and oxidative stress in mitochondria.[unboundmedicine.com] Register Effect of Selenium and Vitamin E Deficiency on Nitrofurantoin Toxicity in the Chick - 24 Hours access EUR 36.00 GBP 28.00 USD 45.00 Rental This article is also available[jn.nutrition.org]

  • Urinary Tract Disease

    Nitrofurantoin The mechanism is not fully understood, but it directly causes selective damage to microbial DNA, which metabolises the toxic intermediates of nitrofurantoin[pathophys.org]

  • Urinary Tract Infection

    Rare cases of severe idiosyncratic liver injury and acute pulmonary toxicity to nitrofurantoin were reported in the literature ( Boelsterli 2006 ; Williams 2006 ).[doi.org] , although its activity is limited to the lower urinary tract, has broad activity against Gram positive and Gram negative pathogens and an acceptable toxicity profile and[doi.org] […] current patterns of antimicrobial resistance in uropathogens clearly argue against the promotion of the use of both trimethoprim/ sulfamethoxazole and ciprofloxacin. 34 35 36 Nitrofurantoin[doi.org]

  • Acute Cystitis

    Rare cases of severe idiosyncratic liver injury and acute pulmonary toxicity to nitrofurantoin were reported in the literature ( Boelsterli 2006 ; Williams 2006 ).[doi.org] , although its activity is limited to the lower urinary tract, has broad activity against Gram positive and Gram negative pathogens and an acceptable toxicity profile and[doi.org] […] current patterns of antimicrobial resistance in uropathogens clearly argue against the promotion of the use of both trimethoprim/ sulfamethoxazole and ciprofloxacin. 34 35 36 Nitrofurantoin[doi.org]

  • Peripheral Neuropathy

    […] end products (AGEs) [10] [31] [32] Metabolic and endocrine diseases: diabetes mellitus, [29] chronic kidney failure, porphyria, amyloidosis, liver failure, hypothyroidism Toxic[en.wikipedia.org] […] causes: drugs ( vincristine, metronidazole, phenytoin, nitrofurantoin, isoniazid, ethyl alcohol, statins ), [ medical citation needed ] organic herbicides TCDD dioxin, organic[en.wikipedia.org]

  • Polyneuropathy

    , organophosphates, PCBs, PNU, podophyllin, saxitoxin, Spanish toxic oil, taxol, tetrodotoxin, thallium, trichloroethylene, TOCP, vinca alkaloids Axonal sensory Almitrine[msdmanuals.com] […] chloride, arsenic, cadmium, carbon disulfide, chlorphenoxy compounds, ciguatoxin, colchicine , cyanide, dapsone , disulfiram , DMAPN, ethylene oxide, lithium , methyl bromide, nitrofurantoin[msdmanuals.com]

  • Chlamydia Infection

    The degradation of these drugs within the microbial cell forms highly toxic electrophilic radicals. Best known are Metronidazol (Flagyl) and Nitrofurantoin (Macrobid).[fertilitysolution.com]

  • Pulmonary Fibrosis

    Chronic pulmonary nitrofurantoin toxicity is uncommon and may develop after 1 month to 6 years of nitrofurantoin treatment [ 1, 2 ].[jmedicalcasereports.com] Nitrofurantoin is a commonly used drug in the treatment and prevention of urinary tract infections.[ncbi.nlm.nih.gov] The acute form of nitrofurantoin toxicity is characterized by fever, cough and rapid onset of dyspnea [ 2 ].[jmedicalcasereports.com]

  • Entrapment Neuropathy

    […] end products (AGEs) [10] [31] [32] Metabolic and endocrine diseases: diabetes mellitus, [29] chronic kidney failure, porphyria, amyloidosis, liver failure, hypothyroidism Toxic[en.wikipedia.org] […] causes: drugs ( vincristine, metronidazole, phenytoin, nitrofurantoin, isoniazid, ethyl alcohol, statins ), [ medical citation needed ] organic herbicides TCDD dioxin, organic[en.wikipedia.org]

  • Lower Urinary Tract Infection

    Nitrofurantoin The mechanism is not fully understood, but it directly causes selective damage to microbial DNA, which metabolises the toxic intermediates of nitrofurantoin[pathophys.org]

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