No Family History: Causes & Reasons

Possible Causes for No Family History

Partial Acquired Lipodystrophy Associated with C3 Nephritic Factor

There is usually no family history of lipodystrophy. Clinical description Onset occurs during childhood or adolescence. [orpha.net]

If there is a family history of similar disease then genetic studies of the complement regulating genes (including CFH, CFI, C3, CFB and the CFH-Related genes) are indicated [rarerenal.org]

Where there is no family history, genetic studies are usually performed on a research basis at present, although in some cases testing may help influence management decisions [rarerenal.org]

Atopic Dermatitis

Genealogy typically includes very little of the medical history of the family, but the medical history could be considered a specific subset of the total history of a family [en.wikipedia.org]

history. [ncbi.nlm.nih.gov]

history of atopy and 2 (2.02%) had both personal and family history of atopy. [doi.org]

Polyps

OBJECTIVE: Prevention of colorectal cancer (CRC) by colonoscopy is recommended according to age and personal/familial history. [ncbi.nlm.nih.gov]

If you have a family history of colon polyps, consider having genetic counseling. [mayoclinic.org]

Polyps prevention If you have a family history of polyps, you have a higher than normal chance of getting polyps too. [healthdirect.gov.au]

Dermatitis

There is often a family history of allergies such as asthma, hay fever, or eczema. People with atopic dermatitis often test positive to allergy skin tests. [nlm.nih.gov]

history of eczema Possible Complications Complications of atopic dermatitis include: Infections of the skin caused by bacteria, fungi, or viruses Permanent scars Side effects [ufhealth.org]

Diagnosis is based on: How your skin looks Your personal and family history Allergy skin testing may be helpful for people with: Hard-to-treat atopic dermatitis Other allergy [nlm.nih.gov]

Osteoporosis

GETTY Osteoporosis: Smoking can increase the risk of developing the condition Family history A family history of the condition - can increase the likelihood of developing [express.co.uk]

Read More >> Osteoporosis Diagnosis Diagnosing osteoporosis is based on a physical examination, diagnostic tests and information about personal and family medical history, [arthritis.org]

This fracture prediction is based on your bone density and other risk factors for fracture, such as family history and smoking. [hopkinsmedicine.org]

Hypercholesterolemia

history of myocardial infarction in relatives c or c Family history of plasma total cholesterol >290 mg/dL in any first- or second-degree relative c or >260 mg/dL in child [jaoa.org]

Cholesterol screening should be considered beginning at age two for children with a family history of premature cardiovascular disease or elevated cholesterol. [beta.labcorp.com]

history of clinical stigmata of FH OR Personal or family history of premature CVD OR Family history of significant hypercholesterolemia, often requiring treatment Individuals [geneticseducation.ca]

Lynch Syndrome Type 1

This study was a case report based on family history examining three patients with a new diagnosis of colorectal adenocarcinoma with ovarian cancer. [ncbi.nlm.nih.gov]

Discussion We present a patient with a family history of multiple cancers. [internationalsurgery.org]

METHODS: Self-reported family cancer history was available for 1353 EC patients and 628 controls. [ncbi.nlm.nih.gov]

Heterozygous Familial Hypercholesterolemia

Autosomal dominant disorders, like FH, tend to appear in each generation in a family. Because of this, people with FH have a family history of heart disease or stroke. [thefhfoundation.org]

Although medical history, family history, and cholesterol levels are important information for diagnosing FH, a healthcare provider may also recommend a genetic test. [ahajournals.org]

Familial Hypercholesterolemia Type 1

Having a family health history of heart disease makes you more likely to develop heart disease yourself. [cdc.gov]

history of myocardial infarction in relatives c or c Family history of plasma total cholesterol >290 mg/dL in any first- or second-degree relative c or >260 mg/dL in child [doi.org]

Take time to collect your family health history of heart disease and share this information with your doctor and other family members. [cdc.gov]

Cardiomyopathy

The family history plays an important role in the cardiomyopathy setting. [moh-it.pure.elsevier.com]

[…] affected without a positive family history 2, 3. [centogene.com]

A 75-year-old patient with a family history of TCM was admitted with suspected ST-segment elevation myocardial infarction. [ncbi.nlm.nih.gov]

Familial Adenomatous Polyposis

history of colon cancer can have pediatric implications when it is part of familial adenomatous polyposis syndrome. [ncbi.nlm.nih.gov]

Diagnosis of CMV warrants ruling out of underlying FAP, irrespective of family history or gastrointestinal symptoms. [ncbi.nlm.nih.gov]

Clinicians should take note of the family history and be prepared to consider much earlier intervention if symptoms occur in a child with a family history of FAP. [ncbi.nlm.nih.gov]

Lower Extremity Arteriosclerosis

“Family history is a major determinant of subclinical peripheral arterial disease in young adults”. [ko.wikipedia.org]

Risk factors for atherosclerosis include: Smoking, or a history of smoking High cholesterol levels in the blood High blood pressure Obesity Family history of heart or vascular [hopkinsmedicine.org]

history of CVD your blood pressure and cholesterol levels if you have certain long-term conditions Depending on your result, you may be advised to make lifestyle changes, [nhs.uk]

Malignant Neoplasm of the Colon

history of colon or rectal cancer, or polyps Family history of hereditary colon or rectal cancer syndromes History of colon or rectal cancer, or adenomatous polyps History [cancer.uvahealth.com]

The age at which such screening tests begin depends upon your risk factors, especially a family history of colon and rectal cancers. [my.clevelandclinic.org]

But people with an increased risk, such as those with a family history of colon cancer, should consider screening sooner. [mayoclinic.org]

Hypertrophic Cardiomyopathy

A family history of early unexplained sudden death, unexplained fainting, unexplained accidents, early heart failure, or early arrhythmia may suggest HCM or another inherited [stanfordhealthcare.org]

The diagnosis of HCM is based on family history, medical history, physical exam,and cardiac testing. [cincinnatichildrens.org]

If you have a diagnosis of HCM or have signs of a heart condition in your family history, you can meet with a genetic counselor to talk about whether genetic testing is right [stanfordhealthcare.org]

Malignant Neoplasm of the Prostate

This information helps us to estimate an individual's risk in a family with a history of prostate cancer. [medschool.lsuhsc.edu]

It has long been known that men with a family history of prostate cancer are at higher risk of getting it themselves. [cancer.org]

Komen®'s My Family Health History Tool My Family Health History tool is a web-based tool that makes it easy for you to record and organize your family health history. [ww5.komen.org]

Lipedema

history of lipedema likely Family history not likely unless primary lymphedema Family history likely Very likely family history Lipedema stages[edit] Lipedema is classified [en.wikipedia.org]

[…] of cellulitis Likely history of cellulitis Possible history of cellulitis Often itching +/- discoloration mistaken for cellulitis Family history: Family history likely Family [en.wikipedia.org]

[…] estimate is 11% adult women (study done in Germany) Unknown; best estimate is a few percent of adult women Low ≥30% of US adults >30% of US adults Presence of cellulitis: No history [en.wikipedia.org]

Acanthosis Nigricans

history of AN or genetic syndrome family history of diabetes mellitus malignancy medication Diagnostic investigations Treatment algorithm Contributors Authors David S. [bestpractice.bmj.com]

In patients with rapid onset and a negative family history, malignancy must be considered as a cause. [mayoclinicproceedings.org]

[…] children with a family history of diabetes (21.2%). [journals.lww.com]

Arteriosclerosis

[…] improve it: do you have a family history of heart disease OR a shared family history of not exercising, smoking, ignoring your diabetes, eating poorly, sleeping too little [verywellhealth.com]

history of CVD your blood pressure and cholesterol levels if you have certain long-term conditions Depending on your result, you may be advised to make lifestyle changes, [nhs.uk]

If you have a family history of severe coronary artery disease and think there is nothing you can do to change that, ask yourself this question before you decide you can't [verywellhealth.com]

Nontoxic Multinodular Goiter

[…] malignancy compared to those without any family history. [kjronline.org]

[…] chest), family history of goiter, hoarseness, and symptoms of hyperthyroidism. [columbiasurgery.org]

In our study, despite significant differences in the frequency of family history between patients with benign and malignant thyroid nodules, family history was not a significant [kjronline.org]

Glaucoma

Glaucoma is the leading cause of blindness for African Americans and Hispanics. 6 Family history: Having a family history of glaucoma increases the risk of developing the [alcon.com]

Family History. Having a family history of glaucoma increases your risk of developing glaucoma. Medical Conditions. [visionsource.com]

If you are over 60 years old, you should have regular eye exams regardless of family history. [singhealth.com.sg]

Aneurysm

[…] anyone, those with a family history of a brain aneurysm should take extra precautionary steps. [centracare.com]

Your doctor will assess the size, location and appearance of your aneurysm, and your medical and family history, to clarify the risk of rupture. [mayoclinic.org]

Smith seeking medical attention because of their family history, their lives were saved due to early detection. [northwell.edu]

Familial Papillary Thyroid Carcinoma with Papillary Renal Cell Carcinoma

If you are concerned about your family history and think your family may have HPRC, consider asking the following questions: Does my family history increase my risk of developing [cancer.net]

History, Physical Examination, and Initial Investigations He has no other symptoms, no weight changes, no history of radiation exposure to the neck, and no family history [jcomjournal.com]

Family history of kidney cancer People with a strong family history of renal cell cancer (without one of the known inherited conditions listed below) have a higher chance [cancer.org]

Syncope

[…] cardiac cause of syncope. 8 With no alarming event history, a negative family history, a normal physical examination, and normal ECG, most patients and families can be given [healio.com]

Family history is positive in 75% of cases. [pedclerk.bsd.uchicago.edu]

In young subjects, there is often a family history in first-degree relatives. [accessmedicine.mhmedical.com]

Cardiogenic Syncope

Symptoms Prior to episode - chest pain, palpitations, dyspnoea, visual disturbance Following episode - tongue biting, incontinence, post-ictal Duration Concomitant illnesses Family [casa.gov.au]

[…] sudden death event, family history of sudden death Normal resting ECG Coronary angiography; cardiac MRI Acquired coronary artery diseases Chest pain syndrome; family history [aafp.org]

Family history of children and adolescents with neurocardiogenic syncope. Pediatr Cardiol. 2008;29:227. doi: 10.1007/s00246-007-9099-6 [journals.uran.ua]

Malignant Neoplasm of the Ovary

If you have a family history of ovarian cancer or breast cancer, talk to your doctor about your risk of ovarian cancer. [mayoclinic.org]

If you have a family history of ovarian cancer, your GP may refer you to a genetics specialist to discuss the option of genetic testing to check your ovarian cancer risk. [nhs.uk]

For individuals who meet the family history criteria but have tested negative for a genetic mutation known to increase susceptibility to the disease, the risk of developing [mskcc.org]

Multiple Self-Healing Squamous Epithelioma

CDKN2A/B deletion and a significant family history }, author={Andrew K. [semanticscholar.org]

His mother is alive without a personal or significant family history of neoplasia. [ncbi.nlm.nih.gov]

@inproceedings{Chan2017FamilialMS, title={Familial melanoma-astrocytoma syndrome: synchronous diffuse astrocytoma and pleomorphic xanthoastrocytoma in a patient with germline [semanticscholar.org]

Colon Polyp

Those with a family history of colon cancer or colon polyps may need to be screened at an earlier age or more often. [medlineplus.gov]

Earlier screening may be recommended in some situations based on family history. [gastronorth.com.au]

You should have a repeat colonoscopy usually 1 to 10 years later, depending on: Your age and general health Number of polyps you had Size and type of the polyps Family history [medlineplus.gov]

Muscular Dystrophy

People with a family history of the disorder may want to seek genetic counseling. [web.archive.org]

The health care provider will ask a series of questions about the patient’s family history and medical history, including any problems affecting the muscles that the patient [web.archive.org]

Because this is an inherited disorder, risks include a family history of Duchenne muscular dystrophy. Symptoms most often appear before age 6. [web.archive.org]

Familial Papillary or Follicular Thyroid Carcinoma

[…] as opposed to patients with a negative family history. [omicsonline.org]

Obviously, a family history does not modify these managements. [scielo.br]

You or a family member has MEN 2, which causes benign and cancerous tumors of endocrine glands You have a family history of FNMTC, a condition in which two or more family [nsgc.org]

Aortic Aneurysm and Dissection

Family history. People who have a family history of aortic aneurysm are at increased risk of having one. [mayoclinic.org]

Risk of aortic aneurism is increased in the presence of risk factors such as family history of aneurysm disease; pre-existing aortic aneurysm and/or aortic dissection; Marfan [gov.uk]

Additional evaluations may be appropriate based on the individual’s history, family history, or specific gene associated with the diagnosis. [invitae.com]