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590 Possible Causes for No Muscle Weakness, Pediatric Disorder, Wheelchair Bound

  • Duchenne Muscular Dystrophy

    Children suffering from this disease eventually become wheelchair bound and die in their late teens.[ncbi.nlm.nih.gov] BACKGROUND AND PURPOSE: Duchenne muscular dystrophy (DMD) is a lethal progressive pediatric muscle disorder and genetically inherited as an X-linked disease that caused by[ncbi.nlm.nih.gov] Occasionally, however, females who carry a DMD gene mutation may have muscle weakness and cramping.[ghr.nlm.nih.gov]

  • Becker Muscular Dystrophy

    Two patients became wheelchair bound in their 40s or beyond, while the other 2 (aged 73 and 69, respectively) were still able to walk at the time of examination.[ncbi.nlm.nih.gov] Little is known about parental motivations and expectations for clinical trials for rare pediatric disorders.[ncbi.nlm.nih.gov] Later symptoms Muscle weakness: Affects the proximal muscles of the limbs mainly.[patient.info]

  • Facioscapulohumeral Muscular Dystrophy

    However, the clinical spectrum of facioscapulohumeral muscular dystrophy (FSHD) ranges from asymptomatic individuals with minimal clinical signs to patients who are wheelchair-bound[ncbi.nlm.nih.gov] Complications of Neuromuscular Disorders. In Epp, Jr., CH & Bowen Jr., Complications in Pediatric Orthopaedic Surgery, 627-630,1995 Tachdjian M.O.[gait.aidi.udel.edu] BACKGROUND: Although muscle weakness is a hallmark of facioscapulohumeral muscular dystrophy (FSHD), the molecular mechanisms that lead to weakness in FSHD remain largely[ncbi.nlm.nih.gov]

  • Friedreich Ataxia

    Trinucleotide expansion length was determined and lymphocyte frataxin levels measured. p.R165P mutation carriers became wheelchair bound early, but had retained reflexes,[ncbi.nlm.nih.gov] Leigh syndrome (subacute necrotizing encephalomyopathy) is a rare, highly morbid and fatal pediatric disorder that results in severe neurological and neuromuscular dysfunction[bioelectron.com] In addition to neuropathological disabilities such as ataxia, sensory loss, and muscle weakness, common signs are scoliosis, foot deformity, and hypertrophic cardiomyopathy[ncbi.nlm.nih.gov]

  • Erb Muscular Dystrophy

    Once wheelchair-bound, patients with MDs tend to develop worsening contractures, osteopenia (initially, followed by osteoporosis), and rapidly progressive scoliosis.[emedicine.medscape.com] Weakness is generally asymmetric and may spare the deltoid, supraspinatus, and infraspinatus muscles.[checkorphan.org] Muscle weakness may spread from the proximal muscles to affect distal muscles.[rarediseases.org]

  • Spinal Muscular Atrophy Type 1

    They typically have a normal lifespan; however, as with all forms of SMA, weakness gets progressively worse and they usually will be wheelchair bound.[smasupport.com] However, you may want to consider: A physical therapist who is experienced in pediatrics and developmental disorders.[moveforwardpt.com] AIM: This study described end-of-life care for children affected by spinal muscular atrophy type 1 (SMA1), which is characterised by progressive muscle weakness and develops[ncbi.nlm.nih.gov]

  • Glycogen Storage Disease Type 2

    Within the follow-up period, one patient became wheelchair bound, mechanical ventilation was initiated in four patients, and eight patients needed to increase their number[ojrd.com] Nomenclature for Conditions based upon “Naming and Counting Disorders (Conditions) Included in Newborn Screening Panels.” Pediatrics. 2006; 117 (5) Suppl: S308-S314.[hrsa.gov] Dyspnea secondary to diaphragm or respiratory muscle weakness may also be observed.[symptoma.com]

  • Spinal Muscular Atrophy

    They typically have a normal lifespan; however, as with all forms of SMA, weakness gets progressively worse and they usually will be wheelchair bound.[smasupport.com] The Pediatric SMA Clinical Research Center, which operates conjointly with the Pediatric Neuromuscular Clinic at Columbia University, is organized according to a team model[columbiasma.org] We report the case of a male who presented in infancy with motor delay and muscle weakness.[ncbi.nlm.nih.gov]

  • Camurati-Engelmann Syndrome

    The severity of limb pain varied from being transient and subsiding without any intervention (patient 2) to making the subject wheelchair-bound (patient 4).[synapse.koreamed.org] Pediatrics 1984 ; 74 : 399 –405. 3 Crisp AJ, Brenton DP. Engelmann's disease of bone—a systemic disorder?[academic.oup.com] Patients generally present with pain in the extremities, waddling gait, easy fatigability, and muscle weakness.[orpha.net]

  • Osteogenesis Imperfecta

    We are reporting the use of combined spinal-epidural anesthesia for a prolonged surgery (multiple osteotomies) of lower limbs in a 10-year-old wheelchair-bound child with[ncbi.nlm.nih.gov] Neurology and Musculoskeletal disorders and Home care, Astrid Lindgren Children's Hospital at Karolinska University Hospital, Stockholm, Sweden.[ncbi.nlm.nih.gov] In OI Type IV muscle weakness has important functional consequences.[iofbonehealth.org]

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